PTPN9 - protein tyrosine phosphatase non-receptor type 9 Gene

中文名称：蛋白酪氨酸磷酸酶非受体 9 型

种属: Homo sapiens

同用名: MEG2; PTPMEG2

关于 PTPN9

功能概要

该基因编码的蛋白质是蛋白酪氨酸磷酸酶 (PTP) 家族的成员。已知 PTP 是调节多种细胞过程的信号分子，包括细胞生长、分化、有丝分裂周期和致癌转化。该 PTP 包含一个与酵母 SEC14 具有显着相似性的 N 末端结构域，后者是一种具有磷脂酰肌醇转移活性的蛋白质，是酵母中通过高尔基复合体分泌蛋白质所必需的。发现该 PTP 被多磷酸肌醇激活，并被认为参与调节吞噬作用的信号事件。[RefSeq 提供，2008 年 7 月]

The protein encoded by this gene is a member of the protein tyrosine Phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an N-terminal domain that shares a significant similarity with yeast SEC14, which is a protein that has phosphatidylinositol transfer activity and is required for protein secretion through the Golgi complex in yeast. This PTP was found to be activated by polyphosphoinositide, and is thought to be involved in signaling events regulating phagocytosis. [provided by RefSeq, Jul 2008]