2. Others Epigenetics Apoptosis
  3. Fluorescent Dye Histone Methyltransferase Apoptosis
  4. PRMT5-targeted fluorescent ligand-1

PRMT5-targeted fluorescent ligand-1 (Compound 7) 是一种 PRMT5 靶向荧光配体，可抑制 PRMT5，IC50 为 29.39 nM。PRMT5-targeted fluorescent ligand-1 表现出细胞成像活性，在 MCF-7 中表现出良好的荧光信号，IC50 为 29 nM。PRMT5-targeted fluorescent ligand-1 诱导细胞凋亡 (apoptosis)。PRMT5-targeted fluorescent ligand-1 的最大激发波长为 438 nm，最大发射波长为 550 nm。

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PRMT5-targeted fluorescent ligand-1 Chemical Structure

PRMT5-targeted fluorescent ligand-1 Chemical Structure

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PRMT5-targeted fluorescent ligand-1 相关抗体

Top Publications Citing Use of Products

查看 Histone Methyltransferase 亚型特异性产品:

查看所有亚型
EZH1 EZH2 DOT1L SMYD2 SMYD3 SUV39H2/KMT1B EHMT2/G9a/KMT1C EHMT1/GLP/KMT1D SETDB1/KMT2G SETD2/KMT3A NSD2/MMSET/WHSC1 SETD7/KMT7 SETD8/KMT5A PRMT1 PRMT3 PRMT4 PRMT5 PRMT6 PRMT7 PRMT8

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

PRMT5-targeted fluorescent ligand-1 (Compound 7) is a PRMT5-targeted fluorescent ligand, that inhibits PRMT5 with an IC50 of 29.39 nM. PRMT5-targeted fluorescent ligand-1 exhibits cell imaging activity, that exhibits good fluorescence signal in MCF-7 with an IC50 of 29 nM. PRMT5-targeted fluorescent ligand-1 induces apoptosis. PRMT5-targeted fluorescent ligand-1 exhibits a maximal excitation wavelength of 438 nm and a maximal emission wavelength of 550 nm[1].

分子量

741.88

Formula

C43H47N7O5
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

PRMT5-targeted fluorescent ligand-1 相关分类

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  • Do most proteins show cross-species activity?

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Keywords:

PRMT5-targeted fluorescent ligand-1Fluorescent DyeHistone MethyltransferaseApoptosisMCF-7Inhibitorinhibitorinhibit

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