1. JAK/STAT Signaling Stem Cell/Wnt NF-κB
  2. STAT NF-κB
  3. Triacetylresveratrol

Triacetylresveratrol  (Synonyms: 三乙酰基白藜芦醇)

目录号: HY-N1410 纯度: 99.58%
COA 产品使用指南

Triacetylresveratrol 是 Resveratrol 的乙酰化类似物。Triacetylresveratrol 降低 STAT3NF-κB 磷酸化。具有抗癌作用。

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Triacetylresveratrol Chemical Structure

Triacetylresveratrol Chemical Structure

CAS No. : 42206-94-0

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10 mM * 1 mL in DMSO ¥169
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50 mg ¥154
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100 mg ¥200
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250 mg ¥380
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1 g ¥803
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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Triacetylresveratrol, an acetylated analog of Resveratrol. Triacetylresveratrol decreases the phosphorylation of STAT3 and NF-κB in a dose- and time- dependent manner in PANC-1 and BxPC-3 cells. Anticancer effects[1].

IC50 & Target[1]

NF-κB

 

STAT3

 

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
A549 IC50
3.4 μM
Compound: 92
Anticancer activity against human A549 cells assessed as cell growth inhibition measured after 72 hrs by MTT assay
Anticancer activity against human A549 cells assessed as cell growth inhibition measured after 72 hrs by MTT assay
[PMID: 32485531]
A549 IC50
9.43 μM
Compound: 92
Anticancer activity against human A549 cells assessed as cell growth inhibition measured after 72 hrs by MTT assay
Anticancer activity against human A549 cells assessed as cell growth inhibition measured after 72 hrs by MTT assay
[PMID: 32485531]
HeLa IC50
3.4 μM
Compound: 92
Anticancer activity against human HeLa cells assessed as cell growth inhibition measured after 72 hrs by MTT assay
Anticancer activity against human HeLa cells assessed as cell growth inhibition measured after 72 hrs by MTT assay
[PMID: 32485531]
体外研究
(In Vitro)

Triacetylresveratrol significantly down-regulates anti-apoptotic Bcl-2 family protein Mcl-1 and up-regulates pro-apoptotic Bcl-2 family proteins Bim and Puma. Triacetylresveratrol inhibits cell viability, and induces apoptosis of pancreatic cancer cells in a concentration and incubation time-dependent manner[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

354.35

Formula

C20H18O6

CAS 号
性状

固体

颜色

White to off-white

中文名称

三乙酰基白藜芦醇

结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 2 years
-20°C 1 year
溶解性数据
细胞实验: 

DMSO 中的溶解度 : 125 mg/mL (352.76 mM; 超声助溶; 吸湿的 DMSO 对产品的溶解度有显著影响,请使用新开封的 DMSO)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 2.8221 mL 14.1103 mL 28.2207 mL
5 mM 0.5644 mL 2.8221 mL 5.6441 mL
查看完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效
储备液的保存方式和期限:-80°C, 2 years; -20°C, 1 year。-80°C储存时,请在2年内使用, -20°C储存时,请在1年内使用。

  • 摩尔计算器

  • 稀释计算器

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量
=
浓度
×
体积
×
分子量 *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start)

C1

×
体积 (start)

V1

=
浓度 (final)

C2

×
体积 (final)

V2

动物溶解方案计算器
请输入动物实验的基本信息:

给药剂量

mg/kg

动物的平均体重

g

每只动物的给药体积

μL

动物数量

由于实验过程有损耗,建议您多配一只动物的量
计算结果
工作液所需浓度 : mg/mL
纯度 & 产品资料
参考文献

完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效
储备液的保存方式和期限:-80°C, 2 years; -20°C, 1 year。-80°C储存时,请在2年内使用, -20°C储存时,请在1年内使用。

可选溶剂 浓度 溶剂体积 质量 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.8221 mL 14.1103 mL 28.2207 mL 70.5517 mL
5 mM 0.5644 mL 2.8221 mL 5.6441 mL 14.1103 mL
10 mM 0.2822 mL 1.4110 mL 2.8221 mL 7.0552 mL
15 mM 0.1881 mL 0.9407 mL 1.8814 mL 4.7034 mL
20 mM 0.1411 mL 0.7055 mL 1.4110 mL 3.5276 mL
25 mM 0.1129 mL 0.5644 mL 1.1288 mL 2.8221 mL
30 mM 0.0941 mL 0.4703 mL 0.9407 mL 2.3517 mL
40 mM 0.0706 mL 0.3528 mL 0.7055 mL 1.7638 mL
50 mM 0.0564 mL 0.2822 mL 0.5644 mL 1.4110 mL
60 mM 0.0470 mL 0.2352 mL 0.4703 mL 1.1759 mL
80 mM 0.0353 mL 0.1764 mL 0.3528 mL 0.8819 mL
100 mM 0.0282 mL 0.1411 mL 0.2822 mL 0.7055 mL
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Triacetylresveratrol
目录号:
HY-N1410
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