2. Anti-infection Cell Cycle/DNA Damage Apoptosis
  3. Virus Protease Topoisomerase Apoptosis
  4. Anthraquinone

Anthraquinone  (Synonyms: 蒽醌)

目录号: HY-N0354 纯度: 99.12%
COA 产品使用指南 技术支持

Anthraquinone 被用作染料和农用化学品的前体，存在于不同的生物体中，如细菌、真菌、植物和一些动物。Anthraquinone 具有生物活性：抗癌、抗炎、利尿、抗关节炎、抗真菌、抗菌、抗疟疾和抗氧化。Anthraquinone 在植物的初级代谢中也起着重要作用，通过作用于电子传递链抑制光合作用过程中的能量转移。Anthraquinone 能够插入到 DNA 中，并抑制拓扑异构酶II (topo II) 酶，导致细胞通过凋亡 (Apoptosis) 死亡。

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Anthraquinone Chemical Structure

Anthraquinone Chemical Structure

CAS No. : 84-65-1

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25 g ￥100
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50 g ￥160
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Customer Review

Other Forms of Anthraquinone:

Anthraquinone 相关抗体

Top Publications Citing Use of Products

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Topoisomerase Topo I Topo II

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Anthraquinone is used as a precursor for dye formation and agrochemicals, existing in different organisms, such as bacteria, fungi, plants, and some animals. Anthraquinone has biological activities: anticancer, antiinflammatory, diuretic, antiarthritic, antifungal, antibacterial, antimalarial and antioxidant. Anthraquinone also plays an important role in the primary metabolism of plants by acting on the electron transport chain through the inhibition of energy transfer in the photosynthetic process. Anthraquinone can intercalates into DNA and inhibits the topoisomerase II (topo II) enzyme, resulting in cell death via Apoptosis[1][2][3][4].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
A2780 IC50
0.58 μM
Compound: 12
Antiproliferative activity against human A2780 cells after 2 days by alamar-blue assay
Antiproliferative activity against human A2780 cells after 2 days by alamar-blue assay
[PMID: 19028102]
AGS IC50
> 100 μM
Compound: 1B
Cytotoxicity against human AGS cells assessed as cell viability after 72 hrs by MTT assay
Cytotoxicity against human AGS cells assessed as cell viability after 72 hrs by MTT assay
[PMID: 23454511]
HL-60 IC50
> 100 μM
Compound: 1B
Cytotoxicity against human HL60 cells assessed as cell viability after 72 hrs by MTT assay
Cytotoxicity against human HL60 cells assessed as cell viability after 72 hrs by MTT assay
[PMID: 23454511]
J82 IC50
> 100 μM
Compound: 1B
Cytotoxicity against human J82 cells assessed as cell viability after 72 hrs by MTT assay
Cytotoxicity against human J82 cells assessed as cell viability after 72 hrs by MTT assay
[PMID: 23454511]
MRC5 IC50
> 100 μM
Compound: 1B
Cytotoxicity against human MRC5 cells assessed as cell viability after 72 hrs by MTT assay
Cytotoxicity against human MRC5 cells assessed as cell viability after 72 hrs by MTT assay
[PMID: 23454511]
SK-MES-1 IC50
> 100 μM
Compound: 1B
Cytotoxicity against human SKMES1 cells assessed as cell viability after 72 hrs by MTT assay
Cytotoxicity against human SKMES1 cells assessed as cell viability after 72 hrs by MTT assay
[PMID: 23454511]
体外研究
(In Vitro)

Anthraquinone (0.2 mg/mL，3 分钟) 在体外表现出强大的抗氧化活性[2]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Anthraquinone 相关抗体:
分子量

208.21

Formula

C14H8O2
CAS 号
性状

固体

颜色

Light yellow to yellow

中文名称

蒽醌
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
溶解性数据
细胞实验： 

DMSO 中的溶解度 : 2 mg/mL (9.61 mM; 超声助溶 (<60°C); 吸湿的 DMSO 对产品的溶解度有显著影响，请使用新开封的 DMSO)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 4.8028 mL 24.0142 mL 48.0284 mL
5 mM 0.9606 mL 4.8028 mL 9.6057 mL
查看完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month。-80°C储存时，请在6个月内使用，-20°C储存时，请在1个月内使用。

  • 摩尔计算器

  • 稀释计算器

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量
=
浓度
×
体积
×
分子量 *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start)

C1

×
体积 (start)

V1

=
浓度 (final)

C2

×
体积 (final)

V2

动物溶解方案计算器
请输入动物实验的基本信息：

给药剂量

mg/kg

动物的平均体重

g

每只动物的给药体积

μL

动物数量

只
由于实验过程有损耗，建议您多配一只动物的量
计算结果
工作液所需浓度 : mg/mL
纯度 & 产品资料

纯度: 99.12%

COA (291 KB) HNMR (126 KB) RP-HPLC (190 KB)

产品使用指南 (1538 KB)
参考文献

Anthraquinone 相关分类

完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month。-80°C储存时，请在6个月内使用，-20°C储存时，请在1个月内使用。

可选溶剂 浓度 溶剂体积 质量 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 4.8028 mL 24.0142 mL 48.0284 mL 120.0711 mL
5 mM 0.9606 mL 4.8028 mL 9.6057 mL 24.0142 mL
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Anthraquinone84-65-1蒽醌Virus ProteaseTopoisomeraseApoptosisdyeagrochemicalsanticancerantiinflammatorydiureticantiarthriticantifungalantibacterialantimalarialantioxidanttopoisomerase IIInhibitorinhibitorinhibit

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