2. Gene
  3. ARC - activity regulated cytoskeleton associated protein Gene

ARC - activity regulated cytoskeleton associated protein Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：活性调节细胞骨架相关蛋白

种属: Homo sapiens

同用名: hArc; Arg3.1

基因 ID: 23237 | 基因类型: protein coding

关于 ARC

Cytogenetic location: 8q24.3 Genomic coordinates (GRCh38): 8:142,611,049-142,614,479 (from NCBI)

This gene has 2 transcripts (splice variants) and 104 orthologues. Biased expression in adrenal (RPKM 5.5), brain (RPKM 5.4) and 9 other tissues.

功能概要

预测启用 mRNA 结合活性。参与细胞迁移；细胞骨架组织；和细胞形态发生的调节。位于细胞质和质膜中。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable mRNA binding activity. Involved in cell migration; Cytoskeleton organization; and regulation of cell morphogenesis. Located in cytoplasm and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

ARC 基因产物(2)

mRNA Protein Name
NM_001412852.1 NP_001399781.1 activity-regulated cytoskeleton-associated protein
NM_015193.5 NP_056008.1 activity-regulated cytoskeleton-associated protein
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables mRNA binding IDA
IDA: 通过直接分析推断
33175445 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
32296183 GOA
enables structural molecule activity IDA
IDA: 通过直接分析推断
33175445 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cell migration IMP
IMP: 通过突变表型推断
21834987 GOA
involved in cytoskeleton organization IMP
IMP: 通过突变表型推断
21834987 GOA
involved in regulation of cell morphogenesis IMP
IMP: 通过突变表型推断
21834987 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasm IDA
IDA: 通过直接分析推断
21834987 GOA
located in plasma membrane IDA
IDA: 通过直接分析推断
21834987 GOA
located in virus-like capsid IDA
IDA: 通过直接分析推断
33175445 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

activity-regulated cytoskeleton-associated protein

ARC/ARG3.1

关联疾病

疾病名称 别名
Hepatocellular Carcinoma

Liver Cancer

Primary Liver Cancer

HCC

Hepatoma

Malignant Neoplasm Of Liver

Liver Neoplasms

Cancer, Hepatocellular

Liver Cell Carcinoma

Lcc

Hepatoblastoma, Somatic

Hepatic Cancer

Primary Malignant Neoplasm Of Liver

Rare Tumor Of Liver And Intrahepatic Biliary Tract

Hepatocellular Carcinoma, Somatic

Hepatocellular Carcinoma, Childhood Type, Somatic

Hepatocellular Cancer, Somatic

Ca Liver - Primary

Hepatic Neoplasm

Malignant Hepato-Biliary Neoplasm

Malignant Neoplasm Of Liver, Not Specified As Primary Or Secondary

Malignant Neoplasm Of Liver, Primary

Malignant Tumor Of Liver

Neoplasm Of Liver

Non-Resectable Primary Hepatic Malignant Neoplasm

Resectable Malignant Neoplasm Of Liver

Resectable Malignant Neoplasm Of The Liver

Primary Liver Carcinoma

Primary Malignant Liver Neoplasm

Primary Cancer Of Liver

Primary Tumor Of The Liver

Rare Tumor Of Liver And Ibt

Hepatocellular Cancer

Neoplasm Of The Liver

Carcinoma, Hepatocellular

Hepatomas

Liver Neoplasm

Liver Carcinoma

Liver And Intrahepatic Biliary Tract Carcinoma

Malignant Hepatobiliary Neoplasm

Adult Primary Hepatocellular Carcinoma

Hepatoblastoma

Carcinoma Of Liver

Malignant Liver Tumour

Malignant Hepatic Tumour
Fragile X Syndrome

FXS

Martin-Bell Syndrome

Fraxa Syndrome

Marker X Syndrome

X-Linked Mental Retardation And Macroorchidism

Fragile X Mental Retardation Syndrome

Fra Syndrome

Mental Retardation, X-Linked, Associated With Marxq28

X-Linked Intellectual Disability And Macroorchidism

Frax Syndrome

Symptomatic Form Of Fragile X Syndrome In Female Carriers

Fragile-X Syndrome

Fraxe Syndrome
Retrograde Amnesia

Amnesia, Retrograde
Amphetamine Abuse
Anxiety

Anxiety Disorder

Anxiety Disorders

Anxiety State

Anxieties

Anxiety Neurosis
Autism Spectrum Disorder

Asd

Autism Spectrum Disorders

Autistic Continuum

Pervasive Developmental Disorder

Pervasive Development Disorder

Autistic Behavior

Autistic Disorder

Autistic

Autistic Disorder Of Childhood Onset

Infantile Autism

Childhood Autism

Kanner Syndrome

Pervasive Developmental Delay Nos

Pervasive Developmental Disorder, Not Otherwise Specified
Amnestic Disorder

Amnesia

Amnestic Syndrome

Korsakoff'S Psychosis Or Syndrome

Amnesic Syndrome

Amnestic Disorder In Conditions Classified Elsewhere

Korsakoff Psychosis Or Syndrome, Nonalcoholic

Nonalcoholic Organic Amnesic Syndrome

Organic Amnesic Syndrome
Autism

Autistic Disorder

Autism Susceptibility 1

Childhood Autism

Autistic Disorder Of Childhood Onset

Infantile Autism

Kanner'S Syndrome

Autistic
Schizophrenia

SCZD

Schizophrenia With Or Without An Affective Disorder

Schizophrenia 12

Schizophrenia, Susceptibility To

Schizophrenia-1

Dementia Praecox

Schizophrenia 1
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Approval
生物活性分子 (6)
目录号 产品名 作用方式
纯度 是否罕见病
HY-10064 Ticagrelor Antagonist 99.98% 是
HY-147080 Avacincaptad pegol sodium Inhibitor 98.53% 否
HY-B0678 Metaxalone 99.77% 否
HY-16216 Gabapentin enacarbil Inhibitor ≥95.0% 是
HY-19638 Cangrelor Antagonist / 否
HY-B0678R Metaxalone (Standard) / 否
Clinical Phase
生物活性分子 (3)
目录号 产品名 作用方式
纯度 Phase
HY-147079 Egaptivon pegol Inhibitor 92.75% Phase 2
HY-153480 ARC19499 Inhibitor 93.65% Phase 1
HY-19845 Ordopidine Antagonist / Phase 1
Pre-clinical Phase
生物活性分子 (33)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-13248 AR-C155858 Inhibitor 99.62% 否
HY-110126 AR-C118925XX Antagonist ≥99.0% 否
HY-126112 Mephenoxalone 98.57% 否
HY-12709A ARC 239 dihydrochloride Antagonist 99.57% 否
HY-12122A AR-C102222 hydrochloride Inhibitor 99.83% 否
HY-153785 NH2-C6-ARC186 sodium Inhibitor 92.50% 否
HY-153098 ARC186 Inhibitor 94.13% 否
HY-153098A ARC186 sodium Inhibitor 94.13% 否
HY-153480A ARC19499 sodium Inhibitor 93.65% 否
HY-N2673 5-Heptadecylresorcinol Activator 99.83% 否
HY-119996A AR-C141990 hydrochloride Inhibitor ≥98.0% 否
HY-12709 ARC 239 99.71% 否
HY-77734 AR-C133913XX ≥98.0% 否
HY-108633 BYK 49187 Inhibitor / 否
HY-108665 AR-C66096 tetrasodium / 否
HY-119996 AR-C141990 / 否
HY-124270 Sibenadet hydrochloride Agonist / 否
HY-146769 Antimalarial agent 11 Inhibitor / 否
HY-147079A Egaptivon pegol sodium Inhibitor 92.75% 否
HY-153492A Olpasiran sodium Inhibitor / 否
HY-153610 ARC7 99.57% 否
HY-153611 ARC12 ≥99.0% 否
HY-78542S Deshydroxyethoxy Ticagrelor-d7 / 否
HY-B0678S Metaxalone-d3 ≥98.0% 否
HY-B0678S1 Metaxalone-d6 / 否
HY-P4889 (Gly22)-amyloid beta-protein(1-40) / 否
HY-RS00890 ARC Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-W350004 (+)-Arabinogalactan,from larch wood, 80% / 否
HY-107567B Carcinine dihydrochloride Antagonist / 否
HY-118942 Topovale Inhibitor / 否
HY-12122 AR-C102222 Inhibitor / 否
HY-122048 AR-C67085 / 否
HY-148826 Rovunaptabin Inhibitor / 否

直系同源

种属 基因名 来源 基因 ID
Bos taurus ARC VGNC VGNC:26056
Macaca mulatta ARC VGNC VGNC:69998
Rattus norvegicus ARC RGD RGD:62037
Felis catus ARC VGNC VGNC:105871
Mus musculus ARC MGD MGI:88067
Macaca fascicularis ARC NCBI NCBI:102130416
Canis lupus familiaris ARC NCBI
Others ARC NCBI
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z