2. Gene
  3. Hp - haptoglobin Gene

Hp - haptoglobin Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: Ba1-647

基因 ID: 24464 | 基因类型: protein coding

关于 Hp

功能概要

Enables hemoglobin binding activity and identical protein binding activity. Involved in several processes, including response to X-ray; response to growth hormone; and response to vitamin. Located in Golgi apparatus; blood microparticle; and endoplasmic reticulum. Used to study obesity and type 1 diabetes mellitus. Biomarker of several diseases, including artery disease (multiple); diabetes mellitus (multiple); hepatocellular adenoma; kidney failure (multiple); and middle cerebral artery infarction. Human ortholog(s) of this gene implicated in Plasmodium falciparum malaria; artery disease (multiple); gout; hemolytic anemia; and hyperglycemia. Orthologous to several human genes including HP (haptoglobin). [provided by Alliance of Genome Resources, Apr 2022]

Hp 基因产物(1)

mRNA Protein Name
NM_012582.2 NP_036714.2 haptoglobin precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables hemoglobin binding IDA
IDA: 通过直接分析推断
6279649 RGD
enables identical protein binding IPI
IPI: 通过物理相互作用推断
6863267 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in animal organ regeneration IEP
IEP: 通过表达模式推断
12379430 RGD
involved in liver development IDA
IDA: 通过直接分析推断
16172914 RGD
involved in response to L-ascorbic acid IEP
IEP: 通过表达模式推断
9566989 RGD
involved in response to X-ray IEP
IEP: 通过表达模式推断
12379430 RGD
involved in response to cobalamin IEP
IEP: 通过表达模式推断
12769818 RGD
involved in response to dimethyl sulfoxide IEP
IEP: 通过表达模式推断
14757319 RGD
involved in response to electrical stimulus IEP
IEP: 通过表达模式推断
9435654 RGD
involved in response to glucocorticoid IEP
IEP: 通过表达模式推断
9749840 RGD
involved in response to growth hormone IEP
IEP: 通过表达模式推断
16127721 RGD
involved in response to hypoxia IEP
IEP: 通过表达模式推断
3094379 RGD
involved in response to lead ion IEP
IEP: 通过表达模式推断
9082656 RGD
involved in response to lipopolysaccharide IEP
IEP: 通过表达模式推断
16968543 RGD
involved in response to magnesium ion IEP
IEP: 通过表达模式推断
11300617 RGD
involved in response to organic cyclic compound IEP
IEP: 通过表达模式推断
15856910 RGD
involved in response to starvation IEP
IEP: 通过表达模式推断
19053136 RGD
involved in response to xenobiotic stimulus IEP
IEP: 通过表达模式推断
15899029 RGD
involved in spermatogenesis IEP
IEP: 通过表达模式推断
9432136 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in blood microparticle IDA
IDA: 通过直接分析推断
22014850 RGD
located in extracellular space IDA
IDA: 通过直接分析推断
17161237 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

haptoglobin

liver regeneration-related protein LRRG173

zonulin

重组 Hp 蛋白

目录号 产品名 蛋白编号 纯度
HY-P73934 Haptoglobin Protein, Rat (HEK293, His) P06866 (M1-N347) ≥95%

相关产品

Approval
生物活性分子 (6)
目录号 产品名 作用方式
纯度 是否罕见病
HY-101588 Gefapixant Antagonist 99.33% 是
HY-B0933 Gadoteridol 98.5% 否
HY-17410 Iloperidone Antagonist 99.97% 否
HY-101588A Gefapixant citrate Antagonist 99.23% 否
HY-B0933A Gadoteridol pentahydrate / 否
HY-17410A Iloperidone hydrochloride Antagonist / 否
Clinical Phase
生物活性分子 (5)
目录号 产品名 作用方式
纯度 Phase
HY-101103 HP-β-CD 99.74% Phase 3
HY-127165 Velnacrine Inhibitor / Phase 3
HY-123857 JNJ-55308942 Antagonist 99.92% Phase 2
HY-117508 JNJ-54175446 Antagonist 99.30% Phase 2
HY-113066C Guanosine 5'-diphosphate (sodium), 96% (HPLC) Activator 99.88% Phase 2
Pre-clinical Phase
生物活性分子 (54)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-114364 UDP-Galactose disodium Agonist 99.42% 否
HY-136026 Camlipixant Antagonist 99.94% 否
HY-15568 A-317491 Antagonist 98.77% 否
HY-A0104J HPMC (Type II,Viscosity:5mPa.s) / 否
HY-122578 P53R3 p53 Inhibitor 99.94% 否
HY-151480 HP590 98.59% 否
HY-110329 ML179 Agonist 99.83% 否
HY-15568A A-317491 sodium salt hydrate Antagonist 99.88% 否
HY-A0104D HPMC (Type I,Viscosity:4000mPa.s) / 否
HY-P1397A RVD-Hpα TFA Agonist 99.32% 否
HY-154840 4-Thiouridine 5′-triphosphate tetralithium Agonist / 否
HY-146564A HP210 Modulator 98.96% 否
HY-W011246 Velnacrine maleate Inhibitor ≥98.0% 否
HY-W050088 Isoxepac 99.92% 否
HY-146564 R-HP210 98.21% 否
HY-A0104C HPMC (Type I,Viscosity:400mPa.s) / 否
HY-E70058 α-1-3,4 Fucosyltransferase, helicobacter pylori 90.00% 否
HY-127165S2 Velnacrine-d4 hydrochloride 98.60% 否
HY-A0104K HPMC (Type II,Viscosity:3mPa.s) / 否
HY-127165S Velnacrine-d3 / 否
HY-17410S Iloperidone-d3 Antagonist / 否
HY-106508 Fendosal Inhibitor / 否
HY-127165S1 Velnacrine-d3 maleate / 否
HY-127165S3 Velnacrine-d4 / 否
HY-136092 Androsta-1,4,6-triene-3,17-dione Inhibitor / 否
HY-143576 P2X3 antagonist 37 Antagonist / 否
HY-145690 HP1328 Inhibitor / 否
HY-145691 HP1142 Inhibitor / 否
HY-146561 S-HP210 Modulator 98.12% 否
HY-150524 UDP-Galactose Agonist / 否
HY-153710 P2X3 antagonist 38 Antagonist / 否
HY-15376 Besipirdine Antagonist / 否
HY-154840A 4-Thiouridine 5′-triphosphate tetrasodium Agonist / 否
HY-159183 THP-NCS / 否
HY-159184 THP-Mal / 否
HY-167855 MRS4833 Antagonist / 否
HY-17410S1 Iloperidone-d3 hydrochloride Antagonist / 否
HY-A0104A HPMC (Type I,Viscosity:30mPa.s) / 否
HY-A0104B HPMC (Type I,Viscosity:100mPa.s) / 否
HY-A0104E HPMC (Type II,Viscosity:100mPa.s) / 否
HY-A0104F HPMC (Type II,Viscosity:400mPa.s) / 否
HY-A0104G HPMC (Type II,Viscosity:4000mPa.s) / 否
HY-A0104H HPMC (Type II,Viscosity:15000mPa.s) / 否
HY-A0104I HPMC (Type II,Viscosity:100000mPa.s) / 否
HY-P10539 Hp1404 Inhibitor / 否
HY-P1397 RVD-Hpα Agonist / 否
HY-RS06331 HP Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS06332 HP1BP3 Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-W050088S Isoxepac-d6 / 否
HY-105463 Saptomycin D Inhibitor / 否
HY-106016 HP 184 Activator / 否
HY-14607 Besipirdine hydrochloride Inhibitor / 否
HY-168117 HP-101 Inhibitor / 否
HY-108668 TC-P 262 Inhibitor / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Hp NCBI NCBI:3240
Canis familiaris Hp NCBI
Felis catus Hp NCBI NCBI:100144610
Macaca fascicularis Hp NCBI
Mus musculus Hp NCBI NCBI:15439
Susscrofa domestica Hp NCBI
Macaca mulatta Hp NCBI NCBI:706640
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