1. Gene
  2. Csf1 - colony stimulating factor 1 Gene

Csf1 - colony stimulating factor 1 Gene

种属: Rattus norvegicus

基因 ID: 78965 | 基因类型: protein coding

关于 Csf1

功能概要

Enables identical protein binding activity. Involved in several processes, including myeloid leukocyte differentiation; odontogenesis; and ossification. Located in extracellular space. Used to study anti-basement membrane glomerulonephritis; high grade glioma; and osteopetrosis. Biomarker of systemic scleroderma. Human ortholog(s) of this gene implicated in interstitial cystitis. Orthologous to human CSF1 (colony stimulating factor 1). [provided by Alliance of Genome Resources, Apr 2022]

Csf1 基因产物(1)

mRNA Protein Name
NM_023981.4 NP_076471.3 macrophage colony-stimulating factor 1 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables identical protein binding IPI
IPI: 通过物理相互作用推断
8357831 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to parathyroid hormone stimulus IEP
IEP: 通过表达模式推断
8304053 RGD
involved in macrophage differentiation IDA
IDA: 通过直接分析推断
20628067 RGD
involved in macrophage differentiation IEP
IEP: 通过表达模式推断
12379742 RGD
involved in ossification IMP
IMP: 通过突变表型推断
12379742 RGD
involved in osteoclast differentiation IMP
IMP: 通过突变表型推断
12379742 RGD
involved in positive regulation of cell migration IMP
IMP: 通过突变表型推断
8304053 RGD
involved in positive regulation of macrophage proliferation IMP
IMP: 通过突变表型推断
8304053 RGD
involved in positive regulation of mononuclear cell migration IMP
IMP: 通过突变表型推断
11499013 RGD
involved in response to lipopolysaccharide IEP
IEP: 通过表达模式推断
24882100 RGD
involved in response to mechanical stimulus IEP
IEP: 通过表达模式推断
20833686 RGD
involved in response to organic cyclic compound IEP
IEP: 通过表达模式推断
19219684 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in extracellular region IDA
IDA: 通过直接分析推断
16673407 RGD
located in extracellular space IDA
IDA: 通过直接分析推断
22846308 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

macrophage colony-stimulating factor 1

CSF-1

MCSF

colony stimulating factor 1 (macrophage)

重组 Csf1 蛋白

目录号 产品名 蛋白编号 纯度
HY-P7247 M-CSF Protein, Rat (CHO) Q8JZQ0-1 (E33-P186) ≥95%
HY-P7386 M-CSF Protein, Rat Q8JZQ0-1 (E33-P186) ≥95%
HY-P70493 M-CSF Protein, Rat (HEK293) Q8JZQ0 (E33-R254) ≥95%

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Csf1 NCBI NCBI:1435
Macaca fascicularis Csf1 NCBI NCBI:102141631
Mus musculus Csf1 NCBI NCBI:12977
Macaca mulatta Csf1 NCBI NCBI:702532