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Results for "

mitogen-activated protein kinase

" in MCE Product Catalog:

By Targets:	MAPKAPK2 (MK2) (3) MEK (5) Anaplastic lymphoma kinase (ALK) (1) Apoptosis (1) Autophagy (1) Bacterial (2) CaSR (2) COX (2) DNA/RNA Synthesis (1) ERK (10) Interleukin Related (1) JNK (2) MAP3K (2) MAP4K (2) MDM-2/p53 (1) Microtubule/Tubulin (1) NF-κB (7) p38 MAPK (13) PDGFR (1) Phosphatase (2) PKC (1) RANKL/RANK (1) Reactive Oxygen Species (1) TGF-beta/Smad (3) TGF-β Receptor (1) TNF Receptor (1)
By Research Areas:	Cancer (18) Cardiovascular Disease (2) Endocrinology (1) Infection (3) Inflammation/Immunology (21) Metabolic Disease (3) Neurological Disease (4)

By Targets:

MAPKAPK2 (MK2) (3)

MEK (5)

Anaplastic lymphoma kinase (ALK) (1)

Apoptosis (1)

Autophagy (1)

Bacterial (2)

CaSR (2)

COX (2)

DNA/RNA Synthesis (1)

ERK (10)

Interleukin Related (1)

JNK (2)

MAP3K (2)

MAP4K (2)

MDM-2/p53 (1)

Microtubule/Tubulin (1)

NF-κB (7)

p38 MAPK (13)

PDGFR (1)

Phosphatase (2)

PKC (1)

RANKL/RANK (1)

Reactive Oxygen Species (1)

TGF-beta/Smad (3)

TGF-β Receptor (1)

TNF Receptor (1)

By Research Areas:

Cancer (18)

Cardiovascular Disease (2)

Endocrinology (1)

Infection (3)

Inflammation/Immunology (21)

Metabolic Disease (3)

Neurological Disease (4)

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Targets Recommended: MEK MNK MAPKAPK2 (MK2) ASK1

Cat. No.	Product Name	Target	Research Area	Chemical Structure

HY-148552

Anti-inflammatory agent 35	p38 MAPK ERK NF-κB Interleukin Related TNF Receptor	Inflammation/Immunology
Anti-inflammatory agent 35 (化合物 5a27) 是一种口服有效的姜黄素类似物，具有抗炎活性。Anti-inflammatory agent 35 可阻断丝裂原活化蛋白激酶 (MAPK) 信号和 NF-kB 的核易位。Anti-inflammatory agent 35 还抑制黄中性粒细胞浸润和促炎细胞因子产生。Anti-inflammatory agent 35 在体内研究中显著减轻脂多糖 (LPS) 诱导的急性肺损伤 (ALI)。

HY-15300

Skepinone-L CBS3830	p38 MAPK Autophagy	Inflammation/Immunology
Skepinone-L (CBS3830) 是选择性p38 MAPK抑制剂。

HY-136409

N-Decanoyl-L-homoserine lactone C10-HSL	Bacterial Reactive Oxygen Species	Infection
N-decanoyl-L-homoserine lactone (C10-HSL) 是一种 N-acyl-homoserine lactone (AHL)。N-decanoyl-L-homoserine lactone 可抑制拟南芥的主根生长。N-decanoyl-L-homoserine lactone 处理可引起拟南芥根胞质游离 Ca²⁺ 和活性氧 (ROS) 浓度瞬间和立即升高，增加丝裂原激活蛋白激酶 6 (MPK6) 的活性，并诱导一氧化氮 (NO) 的产生。

HY-139553

Zunsemetinib ATI-450; CDD-450	MAPKAPK2 (MK2)	Inflammation/Immunology
Zunsemetinib (CDD-450) 是一种具有口服活性的 p38α 丝裂原激活蛋白激酶激活蛋白激酶2 (MK2)通路抑制剂。Zunsemetinib 可用于免疫炎症性疾病的研究。

HY-159846

Luvometinib	MEK	Cancer
Luvometinib 是一种具有抗肿瘤活性的丝裂原激活蛋白激酶 (MEK) 抑制剂。

HY-14974

R 1487	p38 MAPK	Inflammation/Immunology
R 1487 是一种有口服活性，高选择性的 p38α 丝裂原活化蛋白激酶抑制剂。R 1487 可用于类风湿关节炎的研究。

HY-N12898

(Z)-Tetradec-7-en-1-ol	p38 MAPK	Others
(Z)-Tetradec-7-en-1-ol 丝裂原活化蛋白激酶 (MAP Kinase) 的激活剂。

HY-161293

p38-α MAPK-IN-6	p38 MAPK	Cancer
p38-α MAPK-IN-6 (compound 3a) 是 p38α 丝裂原激活蛋白激酶抑制剂。

HY-132878

FgGpmk1-IN-1	Others	Infection
FgGpmk1-IN-1 是一种新型的 FgGpmk1 抑制剂，EC₅₀ 值为 3.46 μg/mL。

HY-10508

(R)-PD 0325901CL	MEK	Cancer
(R)-PD 0325901CL 是 PD 0325901CL 的异构体。PD 0325901CL 是参与癌症研究的有丝分裂原活化蛋白激酶 (MEK) 的选择性抑制剂。PD 0325901CL 在体外和体内抑制癌细胞的生长。

HY-P3894

P34cdc2 Kinase Fragment	Microtubule/Tubulin	Others
P34cdc2 Kinase Fragment 与酵母有丝分裂中 DNA 复制的完整度有关。P34cdc2 Kinase 也可以磷酸化丝裂原激活蛋白 MAP2，调节爪蟾卵母细胞减数分裂中的微管聚合活性。

HY-100278

AKP-001	p38 MAPK	Inflammation/Immunology
AKP-001 是一种 p38 丝裂原活化蛋白激酶 (p38 MAPK) 抑制剂。AKP-001 可以抑制炎性细胞因子的产生，可用于风湿性关节炎和炎症性肠病的研究。

HY-139553A

(R)-Zunsemetinib (R)-ATI-450; (R)-CDD-450	Others	Inflammation/Immunology
(R)-Zunsemetinib 是 Zunsemetinib (HY-139553) 的异构体，可作为实验中的对照化合物。Zunsemetinib (CDD-450) 是一种具有口服活性的 p38α 丝裂原激活蛋白激酶激活蛋白激酶2 (MK2)通路抑制剂。Zunsemetinib 可用于免疫炎症性疾病的研究。

HY-139504

Gamcemetinib CC-99677	MAPKAPK2 (MK2)	Inflammation/Immunology
Gamcemetinib (CC-99677) 是一种有效的、共价的、不可逆的丝裂原活化蛋白 (MAP) 激酶活化蛋白激酶 -2 (MK2)通路抑制剂，在生化(IC₅₀=156.3 nM) 和细胞基础检测 (EC₅₀=89 nM) 中均有作用。Gamcemetinib 来自专利 WO2020236636，化合物 1。

HY-119917

Gossypetin	p38 MAPK MEK Bacterial	Infection Cancer
Gossypetin 是六羟基化的类黄酮，是一种有效的 MKK3 和 MKK6 抑制剂，可强烈减弱 MKK3/6-p38 信号传导途径，具有多种药理活性，包括抗氧化，抗菌和抗癌活性。

HY-77251

TAK1/MAP4K2 inhibitor 1 1 篇文献验证	MAP4K MAP3K	Cancer
TAK1/MAP4K2 inhibitor 1 是一种 TAK1 和 MAP4K2 的双重抑制剂，IC₅₀ 值分别为 41.1 nM 和 18.2 nM。

HY-P10414

Klotho-derived peptide 1 KP1 (human)	TGF-beta/Smad p38 MAPK	Inflammation/Immunology
Klotho-derived peptide 1 (KP1 human) 可阻断 TGF-β/TGF-β 受体 2 的相互作用，抑制 TGF-β 诱导的 Smad2/3 和丝裂原活化蛋白激酶 (MAPK) 激活，并在小鼠模型中表现出抗纤维化和肾脏保护作用。

HY-P10414A

Klotho-derived peptide 1 hydrochloride KP1 (human) (hydrochloride)	TGF-beta/Smad p38 MAPK	Inflammation/Immunology
Klotho-derived peptide 1 (KP1 human) hydrochloride 可阻断 TGF-β/TGF-β 受体 2 的相互作用，抑制 TGF-β 诱导的 Smad2/3 和丝裂原活化蛋白激酶 (MAPK) 激活，并在小鼠模型中表现出抗纤维化和肾脏保护作用。

HY-120485

Raxofelast IRFI-016	p38 MAPK ERK PKC	Cardiovascular Disease
Raxofelast (IRFI-016) 是一种抗氧化剂，适用于各种缺血再灌注损伤模型。 Raxofelast 在 H₂O₂丝裂原激活蛋白激酶 (MAPK), ERK 激酶 1, 2 (MEK1,2) 和蛋白激酶 C (PKC) 的激活而不影响 Ras 表达。

HY-N6246

Asperulosidic Acid	NF-κB ERK	Inflammation/Immunology Cancer
车叶草苷酸 Asperulosidic Acid (ASPA) 车叶草苷酸是一种具有生物活性的环烯醚萜苷，从白花蛇舌草 (Hedyotis diffusa Willd) 的草药中提取的。 Asperulosidic Acid (ASPA) 具有抗肿瘤，抗氧化和抗炎作用。 Asperulosidic Acid (ASPA) 通过抑制 NF-κB 和丝裂原活化蛋白激酶 (MAPK) 信号通路抑制炎性细胞因子(TNF-α，IL-6) 释放发挥抗炎作用。

HY-N2484

Methylnissolin Astrapterocarpan	PDGFR ERK	Cardiovascular Disease
黄芪紫檀烷苷 Methylnissolin (Astrapterocarpan) 是从黄芪 (Astragalus membranaceus) 中分离的，可以抑制血小板衍生生长因子 (PDGF)-BB 诱导的细胞增殖，IC₅₀ 为 10 μM。 Methylnissolin 抑制 PDGF-BB 诱导的细胞外信号调节激酶 1/2 (ERIC1/2) 丝裂原活化蛋白 (MAP) 激酶的磷酸化。 Methylnissolin 通过抑制 ERK1/2 MAP 激酶级联反应抑制 PDGF-BB 诱导的血管平滑肌细胞增殖。

HY-17397

Strontium Ranelate 2 篇文献验证 Distrontium renelate; S12911	CaSR	Metabolic Disease
雷尼酸锶 Strontium Ranelate (S12911) 是一种抗骨质疏松活性分子，其作用是通过减少骨吸收并促进骨形成，从而诱导正骨平衡。Strontium Ranelate 还可以激活非骨骼细胞中的钙敏感受体 (CaSR)，从而导致肌醇 1、4、5-三磷酸生成和丝裂原活化的蛋白激酶信号转导。

HY-145026

ERK1/2 inhibitor 4	ERK	Inflammation/Immunology Cancer
ERK1/2 inhibitor 5 是一种有效的ERK1/2抑制剂。丝裂原活化蛋白激酶 (MAPK) 在信号转导通路中起着极其重要的作用，而细胞外信号调节激酶 (ERK) 是MAPK家族的成员。ERK1/2 inhibitor 5 具有研究或预防癌症、炎症或其他增殖性疾病的潜力 (信息提取自专利 WO2020238776A1)。

HY-145027

ERK1/2 inhibitor 5	ERK	Cancer
ERK1/2 inhibitor 5 是一种有效的ERK1/2抑制剂。丝裂原活化蛋白激酶 (MAPK) 在信号转导通路中起着极其重要的作用，而细胞外信号调节激酶 (ERK) 是MAPK家族的成员。ERK1/2 inhibitor 5 具有研究或预防癌症、炎症或其他增殖性疾病的潜力 (信息提取自专利 WO2020238776A1)。

HY-124152

3,4-Dephostatin Methyl-3,4-dephostatin	MAP3K MAP4K Phosphatase	Neurological Disease
3,4-Dephostatin (Methyl-3,4-dephostatin) 是一种蛋白酪氨酸磷酸酶 (PTPase) 抑制剂。3,4-Dephostatin 加速神经生长因子 (NGF) 诱导的 PC12h 细胞神经突起形成。3,4-Dephostatin 维持 NGF 诱导的蛋白质酪氨酸磷酸化，尤其是有丝分裂原激活蛋白 (MAP) 激酶的磷酸化。3,4-Dephostatin 还延长表皮生长因子 (EGF) 诱导的酪氨酸磷酸化和 MAP 激酶的激活。

HY-N4126

6-Demethoxytangeretin	Anaplastic lymphoma kinase (ALK)	Neurological Disease Inflammation/Immunology Cancer
6-去甲氧基三苯甲基黄嘌呤 6-Demethoxytangeretin 6-去甲氧基三苯甲基黄嘌呤是从柑橘 (Citrus reticulata) 分离的黄酮。 6-Demethoxytangeretin 具有抗炎和抗过敏活性，通过间变性淋巴瘤激酶 (ALK) 和丝裂原活化蛋白激酶 (MAPK) 途径抑制人肥大细胞中 IL-6 的产生和基因表达。6-Demethoxytangeretin 促进 CRE 介导的转录 (与海马神经元的学习和记忆相关)。

HY-145025

ERK1/2 inhibitor 3	ERK	Inflammation/Immunology Cancer
ERK1/2 inhibitor 3 是一种有效的ERK1/2抑制剂。丝裂原活化蛋白激酶 (MAPK) 在信号转导通路中起着极其重要的作用，而细胞外信号调节激酶 (ERK) 是MAPK家族的成员。ERK1/2 inhibitor 3 具有研究或预防癌症、炎症或其他增殖性疾病的潜力 (信息提取自专利 WO2021218912A1, 化合物 1)。

HY-145028

ERK1/2 inhibitor 6	ERK	Inflammation/Immunology Cancer
ERK1/2 inhibitor 6 是一种有效的ERK1/2抑制剂。丝裂原活化蛋白激酶 (MAPK) 在信号转导通路中起着极其重要的作用，而细胞外信号调节激酶 (ERK) 是MAPK家族的成员。ERK1/2 inhibitor 6 具有研究或预防癌症、炎症或其他增殖性疾病的潜力 (信息提取自专利 WO2021063335A1, 化合物 1)。

HY-152860

Darizmetinib HRX-0215	p38 MAPK JNK NF-κB MDM-2/p53	Cancer
Darizmetinib 是具有口服活性，强效且选择性的有丝分裂激活蛋白激酶激酶 4 (MKK4) 抑制剂。Darizmetinib 能够增强 MKK7 和 JNK1 信号通路，从而激活转录因子 ATF2 和 ELK1，促进细胞增殖和肝脏再生。Darizmetinib 有望用于防止广泛的肿瘤肝切除术后或小肝移植后的肝功能衰竭的研究。

HY-N6246R

Asperulosidic Acid (Standard)	NF-κB ERK	Inflammation/Immunology Cancer
车叶草苷酸 (Standard) Asperulosidic Acid (Standard) 是 Asperulosidic Acid 的分析标准品。本产品用于研究及分析应用。Asperulosidic Acid (ASPA) 车叶草苷酸是一种具有生物活性的环烯醚萜苷，从白花蛇舌草 (Hedyotis diffusa Willd) 的草药中提取的。 Asperulosidic Acid (ASPA) 具有抗肿瘤，抗氧化和抗炎作用。 Asperulosidic Acid (ASPA) 通过抑制 NF-κB 和丝裂原活化蛋白激酶 (MAPK) 信号通路抑制炎性细胞因子(TNF-α，IL-6) 释放发挥抗炎作用。

HY-17397R

Strontium Ranelate (Standard)	CaSR	Metabolic Disease
雷尼酸锶(Standard) Strontium Ranelate (Standard)是 Strontium Ranelate 的分析标准品。本产品用于研究及分析应用。Strontium Ranelate (S12911) 是一种抗骨质疏松活性分子，其作用是通过减少骨吸收并促进骨形成，从而诱导正骨平衡。Strontium Ranelate 还可以激活非骨骼细胞中的钙敏感受体 (CaSR)，从而导致肌醇 1、4、5-三磷酸生成和丝裂原活化的蛋白激酶信号转导。

HY-168090

Anti-osteoporosis agent-11	p38 MAPK NF-κB RANKL/RANK	Endocrinology
Anti-osteoporosis agent-11 (compound 3k) 是一种靶向破骨细胞的抗骨质疏松化合物。Anti-osteoporosis agent-11 对破骨细胞分化的抑制作用最为显著，IC₅₀ 值为 0.36 μM。此外，Anti-osteoporosis agent-11 通过阻断 rankl 诱导的丝裂原活化蛋白激酶 (MAPK) 和 NF-κB 信号通路，来抑制破骨细胞形成、骨吸收和破骨细胞特异性基因的表达。

HY-18758

IN-1130 1 篇文献验证	TGF-β Receptor	Inflammation/Immunology Cancer
N-1130 是一种高度选择性的转化生长因子-β I 型受体激酶 (ALK5) 抑制剂，对 ALK5 介导的 Smad3 磷酸化的 IC₅₀ 为 5.3 nM。IN-1130 抑制酪蛋白的 ALK5 磷酸化 (IC₅₀=36 nM)，抑制 p38α 丝裂原活化的蛋白激酶 (IC₅₀=4.3 μM)。IN-1130 可抑制阻塞性肾病中的肾纤维化，阻止乳腺癌的肺转移。

HY-142042

3-Hydroxy-4-carboxyalkylamidino-5-arylamino-isothiazoles	MEK TGF-beta/Smad	Neurological Disease Inflammation/Immunology Cancer
3-Hydroxy-4-carboxyalkylamidino-5-arylamino-isothiazoles 是骨形态发生蛋白 2 (BMP2) 的抑制剂，IC₅₀ 为 2.2 μM。3-Hydroxy-4-carboxyalkylamidino-5-arylamino-isothiazoles 是丝裂原活化蛋白激酶 1 (MEK1) 的抑制剂。3-Hydroxy-4-carboxyalkylamidino-5-arylamino-isothiazoles 在 EAE 小鼠模型中表现出抗炎和神经保护活性。

HY-167679

Scio-323	Others	Inflammation/Immunology
Scio-323是一种口服可用的p38丝裂原活化蛋白激酶（MAPK）抑制剂，具有抑制与聚乙烯颗粒相关的慢性炎症反应的潜力。Scio-323的口服抑制方式对骨生成的影响较小。Scio-323在建立聚乙烯颗粒引起的慢性炎症反应后，施用会抑制净骨形成。Scio-323在所有抑制中，类成骨细胞的活性均保持较低水平。Scio-323在存在聚乙烯颗粒的情况下未能改善骨生长。

HY-108543

NSC 95397 最多引用文献 7 篇文献验证	Phosphatase Apoptosis	Cancer
NSC 95397 是一种有效选择性的 Cdc25 双特异性磷酸酶抑制剂 (Cdc25A、Cdc25B 以及 Cdc25C 的 K_i 值分别为 32、96、40 nM，人亚型 Cdc25A、人亚型 Cdc25C 以及 Cdc25B 的 IC₅₀ 值分别为 22.3、56.9、125 nM)。NSC 95397 抑制丝裂原活化蛋白激酶磷酸酶-1 (MKP-1)，并通过 MKP-1 和 ERK1/2 途径抑制结肠癌细胞的增殖并诱导细胞凋亡。

HY-100538A

DTP3 TFA 1 篇文献验证	DNA/RNA Synthesis JNK	Cancer
DTP3 TFA 是一种有效且选择性的 GADD45β/MKK7 抑制剂。DTP3 TFA 靶向 NF-κB 途径下游，具有抗癌活性。

HY-P3412

MMI-0100	MAPKAPK2 (MK2)	Inflammation/Immunology
MMI-0100 是一种细胞渗透性肽抑制剂，抑制丝裂原活化蛋白激酶活化蛋白激酶 II (MK2)。MMI-0100 在体内外减少内膜增生。MMI-0100 抑制 IL-6 表达而不影响 IL-8 表达。MMI-0100 抑制纤维化过程，例如静脉移植疾病。

HY-N0632

Esculentoside A 2 篇文献验证	COX NF-κB	Inflammation/Immunology
商陆皂苷甲 Esculentoside A (EsA)，一种从商陆 Phytolacca esculenta 根部分离出来的三萜皂苷。 Esculentoside A (EsA) 在具有抗炎活性，对环氧合酶-2 (COX-2) 具有选择性抑制活性。 Esculentoside A (EsA) 通过抑制 (NF-ΚB) 和丝裂原活化蛋白激酶 (MAPK) 信号通路抑制 LPS 诱导的急性肺损伤 (ALI) 中的炎症反应。

HY-W015445

SD-169	p38 MAPK	Metabolic Disease
SD-169 是一种有口服活性的 ATP 竞争性 MAPK p38α 抑制剂，其 IC₅₀ 值为 3.2 nM。SD-169 对 p38β MAPK 也有较弱的抑制作用，其 IC₅₀ 值为 122 nM。SD-169 通过抑制 T 细胞的浸润和活化阻止糖尿病的发展。

HY-N0632R

Esculentoside A (Standard)	COX NF-κB	Inflammation/Immunology
商陆皂苷甲 (Standard) Esculentoside A (Standard) 是 Esculentoside A 的分析标准品。本产品用于研究及分析应用。Esculentoside A (EsA)，一种从商陆 Phytolacca esculenta 根部分离出来的三萜皂苷。 Esculentoside A (EsA) 在具有抗炎活性，对环氧合酶-2 (COX-2) 具有选择性抑制活性。 Esculentoside A (EsA) 通过抑制 (NF-ΚB) 和丝裂原活化蛋白激酶 (MAPK) 信号通路抑制 LPS 诱导的急性肺损伤 (ALI) 中的炎症反应。

HY-150605

ERK5-IN-3	ERK	Cancer
ERK5-IN-3 (compound 33j) 是一种有效且选择性的 ERK5 (细胞外信号相关激酶 5) 抑制剂，其 IC₅₀ 为 6 nM。ERK5-IN-3 对 Hela 细胞具有抗增殖活性，其 IC₅₀ 为 31 nM。

HY-107620

PD 198306	MEK	Neurological Disease
PD 198306 是一种选择性 MAPK/ERK 激酶 (MEK) 抑制剂。PD 198306 显著降低 Streptozocin 诱导的 ERK1/2 水平升高。具有抗痛觉过敏作用。

Cat. No.	Product Name	Target	Research Area

HY-100538A

DTP3 TFA 1 篇文献验证	DNA/RNA Synthesis JNK	Cancer
DTP3 TFA 是一种有效且选择性的 GADD45β/MKK7 抑制剂。DTP3 TFA 靶向 NF-κB 途径下游，具有抗癌活性。

HY-P3412

MMI-0100	MAPKAPK2 (MK2)	Inflammation/Immunology
MMI-0100 是一种细胞渗透性肽抑制剂，抑制丝裂原活化蛋白激酶活化蛋白激酶 II (MK2)。MMI-0100 在体内外减少内膜增生。MMI-0100 抑制 IL-6 表达而不影响 IL-8 表达。MMI-0100 抑制纤维化过程，例如静脉移植疾病。

HY-P3894

P34cdc2 Kinase Fragment	Microtubule/Tubulin	Others
P34cdc2 Kinase Fragment 与酵母有丝分裂中 DNA 复制的完整度有关。P34cdc2 Kinase 也可以磷酸化丝裂原激活蛋白 MAP2，调节爪蟾卵母细胞减数分裂中的微管聚合活性。

HY-P10414

Klotho-derived peptide 1 KP1 (human)	TGF-beta/Smad p38 MAPK	Inflammation/Immunology
Klotho-derived peptide 1 (KP1 human) 可阻断 TGF-β/TGF-β 受体 2 的相互作用，抑制 TGF-β 诱导的 Smad2/3 和丝裂原活化蛋白激酶 (MAPK) 激活，并在小鼠模型中表现出抗纤维化和肾脏保护作用。

HY-P10414A

Klotho-derived peptide 1 hydrochloride KP1 (human) (hydrochloride)	TGF-beta/Smad p38 MAPK	Inflammation/Immunology
Klotho-derived peptide 1 (KP1 human) hydrochloride 可阻断 TGF-β/TGF-β 受体 2 的相互作用，抑制 TGF-β 诱导的 Smad2/3 和丝裂原活化蛋白激酶 (MAPK) 激活，并在小鼠模型中表现出抗纤维化和肾脏保护作用。

Species:	Human (39) Mouse (2)
Tag:	His (18) Tag Free (11) Strep (1) GST (19) Flag (2)
Source:	Sf9 insect cells (2) Sf9 insect cells (25) P. pastoris (1) E. coli (13)

Cat. No.	Compare	Product Name	Species	Source

HY-P73848

	JNK1 Protein, Human (sf9, GST) mitogen-activated protein kinase 8; MAPK 8; JNK-46; JNK1; PRKM8	Human	Sf9 insect cells
	JNK1 是一种多功能丝氨酸/苏氨酸蛋白激酶，复杂地调节多种细胞过程，包括细胞增殖、凋亡和分化。JNK1 由 MAP2K4/MKK4 和 MAP2K7/MKK7 激活，磷酸化 AP-1 成分，并影响转录活性。JNK1 Protein, Human (sf9, GST) 是重组的 JNK1 蛋白，由 Sf9 insect cells 表达，带有 N-GST 标签。JNK1 Protein, Human (sf9, GST) 全长 427 个氨基酸，分子量约为 ~65 kDa。

HY-P76532

	p38 gamma/MAPK12 Protein, Human (sf9) mitogen-activated protein kinase 12; Extracellular signal-regulated kinase 6; ERK-6; SAPK3	Human	Sf9 insect cells
	p38 gamma/MAPK12 蛋白是 MAP 激酶通路中重要的丝氨酸/苏氨酸激酶，可以对促炎细胞因子或应激等细胞外刺激做出反应。p38 MAPK 激活转录因子，例如 ELK1 和 ATF2，每个转录因子可磷酸化大约 200 至 300 个底物。p38 gamma/MAPK12 Protein, Human (sf9) 是重组的 p38 gamma/MAPK12 蛋白，由 Sf9 insect cells 表达，不带标签 with residual Gly-Pro in N-terminal。

HY-P702742

	MAP4K1 Protein, Human (sf9) MAP4K1; mitogen-activated protein kinase kinase kinase kinase 1	Human	Sf9 insect cells
	MAP4K1 Protein, Human (sf9) 是重组的 MAP4K1 蛋白，由 Sf9 insect cells 表达，带有 tag Free 标签。MAP4K1 Protein, Human (sf9)

HY-P703054

	ASK3 Protein, Human (sf9, GST) ASK3; MAP3K15; mitogen-activated protein kinase kinase kinase 15;	Human	Sf9 insect cells
	ASK3 Protein, Human (sf9, GST) 是重组的 ASK3 蛋白，由 Sf9 insect cells 表达，带有 GST 标签。ASK3 Protein, Human (sf9, GST) 全长 588 个氨基酸

HY-P700592

	MAP2K6 Protein, Human (Baculovirus, His) MAP2K6; mitogen-activated protein kinase kinase 6; MEK6; MKK6; MAPKK6; PRKMK6; SAPKK3; protein kinase, mitogen-activated, kinase 6 (MAP kinase kinase 6); EC 2.7.12.2; Dual specificity mitogen-activated protein kinase kinase 6; MAP kinase kinase 6; MAPK/ERK kinase 6	Human	Sf9 insect cells
	MKK6 蛋白是参与 MAP 激酶途径的双特异性激酶。MAP2K6 Protein, Human (Baculovirus, His) 是重组的 MAP2K6 蛋白，由 Sf9 insect cells 表达，带有 N-6*His 标签。

HY-P700593

	MAP3K1 Protein, Mouse (His) MEKK; MEKK1; SRXY6; MEKK 1; MAPKKK1; MAP/ERK kinase kinase 1; MAPK/ERK kinase kinase 1; MEK kinase 1; mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase; mitogen-activated protein kinase kinase kinase 1	Mouse	E. coli
	MAP3K1 是蛋白激酶信号转导级联的关键组成部分，在细胞信号传导通路中发挥着至关重要的作用。通过其激酶活性，MAP3K1 通过磷酸化 MAP2K1 和 MAP2K4 来协调 ERK 和 JNK 激酶途径的激活。MAP3K1 Protein, Mouse (His) 是重组的 MAP3K1 蛋白，由 E. coli 表达，带有 N-6*His 标签。

HY-P701730

	P38β Protein, Human (Sf9) MAPK11; mitogen-activated protein kinase 11; MAP kinase 11; MAPK 11; mitogen-activated protein kinase p38 beta; MAP kinase p38 beta; p38b; Stress-activated protein kinase 2b; SAPK2b; p38-2	Human	Sf9 insect cells
	P38β 蛋白是 MAP 激酶通路中重要的丝氨酸/苏氨酸激酶，可响应细胞外刺激，包括促炎细胞因子和身体应激。作为 p38 MAPK 家族的一部分，P38β 直接激活磷酸化许多蛋白质的转录因子，包括 RPS6KA5/MSK1 和 RPS6KA4/MSK2。P38β Protein, Human (Sf9) 是重组的 P38β 蛋白，由 Sf9 insect cells 表达，不带标签。P38β Protein, Human (Sf9) 全长 363 个氨基酸。

HY-P701731

	P38β Protein, Human (Sf9, GST) MAPK11; mitogen-activated protein kinase 11; MAP kinase 11; MAPK 11; mitogen-activated protein kinase p38 beta; MAP kinase p38 beta; p38b; Stress-activated protein kinase 2b; SAPK2b; p38-2	Human	Sf9 insect cells
	P38β 蛋白是 MAP 激酶通路中重要的丝氨酸/苏氨酸激酶，可响应细胞外刺激，包括促炎细胞因子和身体应激。作为 p38 MAPK 家族的一部分，P38β 直接激活磷酸化许多蛋白质的转录因子，包括 RPS6KA5/MSK1 和 RPS6KA4/MSK2。P38β Protein, Human (Sf9, GST) 是重组的 P38β 蛋白，由 Sf9 insect cells 表达，带有 N-GST 标签。P38β Protein, Human (Sf9, GST) 全长 363 个氨基酸。

HY-P701764

	RCK Protein, Human (His) MAP3K19; mitogen-activated protein kinase kinase kinase 19; Regulated in COPD; protein kinase; SPS1/STE20-related protein kinase YSK4	Human	E. coli
	MAP3K19 是一类在细胞内参与信号传导的蛋白激酶。MAP3K19 能直接激活 ERK 和 JNK 通路，并在维持 KRAS 突变型肺癌细胞的生存中发挥重要作用。此外，MAP3K19 还调节哮喘患者中的过敏性气道炎症，它能抑制 TWEAK 刺激的气道上皮反应，包括粘附因子减弱和 RANTES 产生，并抑制哮喘小鼠模型中的过敏性气道炎症。RCK Protein, Human (His) 是重组的 RCK 蛋白，由 E. coli 表达，带有 N-6*His 标签。RCK Protein, Human (His) 全长 305 个氨基酸。

HY-P75921

	MAP3K8/TPL-2 Protein, Human (sf9, GST) mitogen-activated protein kinase kinase kinase 8; TPL-2; MAP3K8; COT; ESTF	Human	Sf9 insect cells
	MAP3K8/TPL-2 对于 LPS 诱导、TLR4 介导的 MAPK/ERK 激活至关重要，从而导致巨噬细胞产生 TNF。它通过负调节 I 型干扰素的产生来调节 T 细胞分化、IFNG 表达和宿主对细菌感染的抵抗力。MAP3K8/TPL-2 Protein, Human (sf9, GST) 是重组的 MAP3K8/TPL-2 蛋白，由 Sf9 insect cells 表达，带有 N-GST 标签。MAP3K8/TPL-2 Protein, Human (sf9, GST) 全长 368 个氨基酸，分子量约为 ~68 kDa。

HY-P76946

	MAP4K2 Protein, Human (sf9, His-GST) mitogen-activated protein kinase kinase kinase kinase 2; GC kinase; MEKKK 2; GCK; RAB8IP	Human	Sf9 insect cells
	MAP4K2是一种丝氨酸/苏氨酸蛋白激酶，是MAP激酶信号转导通路的重要组成部分。它充当 MAPK 激酶激酶 (MAP4K)，激活应激激活蛋白激酶/c-Jun N 末端激酶 (SAP/JNK) 通路，并在较小程度上激活 p38 MAPKs 通路。MAP4K2 Protein, Human (sf9, His-GST) 是重组的 MAP4K2 蛋白，由 Sf9 insect cells 表达，带有 N-His, N-GST 标签。MAP4K2 Protein, Human (sf9, His-GST) 全长 812 个氨基酸，分子量约为 ~116 kDa。

HY-P75223

	ERK2 Protein, Human (sf9, His) mitogen-activated protein kinase 1; MAPK 1; ERT1; ERK-2; p42-MAPK	Human	Sf9 insect cells
	ERK2 蛋白是 MAPK/ERK 级联的关键组成部分，调节多种细胞过程，如转录、翻译、有丝分裂、细胞凋亡、内体动力学和高尔基体断裂。通过磷酸化，它调节底物，包括转录因子、细胞骨架元件、细胞凋亡调节因子、翻译调节因子、蛋白激酶和磷酸酶。ERK2 Protein, Human (sf9, His) 是重组的 ERK2 蛋白，由 Sf9 insect cells 表达，带有 C-His 标签。

HY-P70931

	MAPKSP1 Protein, Human (His) Ragulator Complex protein LAMTOR3; Late Endosomal/Lysosomal Adaptor and MAPK and MTOR Activator 3; MEK-Binding Partner 1; Mp1; mitogen-activated protein kinase kinase 1-Interacting protein 1; mitogen-activated protein kinase Scaffold protein 1; LAMTOR3; MAP2K1IP	Human	E. coli
	MAPKSP1 蛋白，也称为胆色素原脱氨酶 (HMBS)，在血红素生物合成途径中至关重要，可催化四个胆色素原分子顺序聚合形成羟甲基双烷。该过程始于胆色素原或前尿卟啉原的二吡咯甲烷辅助因子的组装。MAPKSP1 Protein, Human (His) 是重组的 MAPKSP1 蛋白，由 E. coli 表达，带有 N-6*His 标签。MAPKSP1 Protein, Human (His) 全长 124 个氨基酸，分子量约为 ~15.0 kDa。

HY-P73334

	p38 delta/MAPK13 Protein, Human (sf9, GST) mitogen-activated protein kinase 13; MAPK 13; PRKM13; SAPK4	Human	Sf9 insect cells
	p38 delta/MAPK13 蛋白是 MAP 激酶途径中重要的丝氨酸/苏氨酸激酶。它协调细胞对细胞因子或应激等刺激的反应，并直接激活转录因子 ELK1 和 ATF2。在该级联中，p38 MAPK（包括 MAPK13）各自磷酸化大约 200 至 300 个底物。p38 delta/MAPK13 Protein, Human (sf9, GST) 是重组的 p38 delta/MAPK13 蛋白，由 Sf9 insect cells 表达，带有 N-GST 标签。

HY-P76533

	p38 gamma/MAPK12 Protein, Human (sf9, His-GST) mitogen-activated protein kinase 12; Extracellular signal-regulated kinase 6; ERK-6; SAPK3	Human	Sf9 insect cells
	p38 gamma/MAPK12 蛋白是 MAP 激酶通路中重要的丝氨酸/苏氨酸激酶，可以对促炎细胞因子或应激等细胞外刺激做出反应。p38 MAPK 激活转录因子，例如 ELK1 和 ATF2，每个转录因子可磷酸化大约 200 至 300 个底物。p38 gamma/MAPK12 Protein, Human (sf9, His-GST) 是重组的 p38 gamma/MAPK12 蛋白，由 Sf9 insect cells 表达，带有 N-His, N-GST 标签。

HY-P703924

	p38 gamma/MAPK12 Protein, Human (Active, sf9, GST) mitogen-activated protein kinase 12；MAP kinase 12; MAPK 12；Extracellular signal-regulated kinase 6 (ERK-6)；mitogen-activated protein kinase p38 gamma (MAP kinase p38 gamma)；Stress-activated protein kinase 3	Human	Sf9 insect cells

HY-P73825

	MEK1 Protein, Mouse (sf9, His-GST) Dual specificity mitogen-activated protein kinase kinase 1; MAPKK 1; MEK 1; Map2k1	Mouse	Sf9 insect cells
	MEK1 蛋白是一种双特异性激酶，在 MAP 激酶通路中发挥着至关重要的作用。MEK1 调节各种细胞过程，如生长、粘附、存活和分化，以及转录、代谢和细胞骨架重排。MEK1 Protein, Mouse (sf9, His-GST) 是重组的 MEK1 蛋白，由 Sf9 insect cells 表达，带有 N-His, N-GST 标签。

HY-P74746

	MKK6 Protein, Human (sf9) Dual specificity mitogen-activated protein kinase kinase 6; MAPKK 6; MEK 6; SAPKK3; MAP2K6	Human	Sf9 insect cells
	MKK6 蛋白是参与 MAP 激酶途径的双特异性激酶。MKK6 Protein, Human (sf9) 是重组的 MKK6 蛋白，由 Sf9 insect cells 表达，不带标签。MKK6 Protein, Human (sf9) 全长 334 个氨基酸，分子量约为 ~37 kDa。

HY-P73335

	p38 alpha/MAPK14 Protein, Human (Activated, sf9, His) mitogen-activated protein kinase 14; MAPK 14; CSBP; MXI2; SAPK2A	Human	Sf9 insect cells
	p38 α/MAPK14 蛋白是 MAP 激酶途径中重要的丝氨酸/苏氨酸激酶。它可以对细胞因子或应激等刺激做出反应，并直接激活转录因子。在这个级联中，p38 MAPK 每个磷酸化大约 200 至 300 个底物，包括下游激酶 RPS6KA5/MSK1 和 RPS6KA4/MSK2，它们对于立即早期基因诱导至关重要。p38 alpha/MAPK14 Protein, Human (Activated, sf9, His) 是重组的 p38 α/MAPK14 蛋白，由 Sf9 insect cells 表达，带有 N-His 标签。p38 alpha/MAPK14 Protein, Human (Activated, sf9, His) 全长 360 个氨基酸，分子量约为 ~43.7 kDa。

HY-P74745

	MKK6 Protein, Human (sf9, His-GST) Dual specificity mitogen-activated protein kinase kinase 6; MAPKK 6; MEK 6; SAPKK3; MAP2K6	Human	Sf9 insect cells
	MKK6 蛋白是参与 MAP 激酶途径的双特异性激酶。MKK6 Protein, Human (sf9, His-GST) 是重组的 MKK6 蛋白，由 Sf9 insect cells 表达，带有 N-His, N-GST 标签。MKK6 Protein, Human (sf9, His-GST) 全长 334 个氨基酸，分子量约为 ~60 kDa。

HY-P702743

	MAP4K4 Protein, Human (sf9, GST) MAP4K4; mitogen-activated protein kinase kinase kinase kinase 4; FLH21957; hepatocyte progenitor kinase like/germinal center kinase like kinase; HGK; HPK/GCK like kinase; NIK	Human	Sf9 insect cells
	MAP4K4 Protein, Human (sf9, GST) 是重组的 MAP4K4 蛋白，由 Sf9 insect cells 表达，带有 GST 标签。MAP4K4 Protein, Human (sf9, GST)

HY-P701679

	ERK3 Protein, Human MAPK6; mitogen-activated protein kinase 6; MAP kinase 6; MAPK 6; Extracellular signal-regulated kinase 3; ERK-3; MAP kinase isoform p97; p97-MAPK	Human	E. coli
	ERK3 蛋白是一种非典型 MAPK，磷酸化 MAP2 和 MAPKAPK5。ERK3/MAPK6 与 MAPKAPK5 相互作用，发生 Ser-189 磷酸化，促进 MAPKAPK5 激活。激活的 MAPKAPK5 会相互磷酸化 ERK3/MAPK6。该复合物的精确功能意义，特别是在细胞周期进入方面，仍然难以捉摸。ERK3 Protein, Human 是重组的 ERK3 蛋白，由 E. coli 表达，不带标签。ERK3 Protein, Human 全长 319 个氨基酸。

HY-P701705

	ASK1 Protein, Human (His) MAP3K5; mitogen-activated protein kinase kinase kinase 5; Apoptosis signal-regulating kinase 1; ASK-1; MAPK/ERK kinase kinase 5; MEK kinase 5; MEKK 5	Human	E. coli
	ASK1 蛋白是 MAP 激酶通路中的关键丝氨酸/苏氨酸激酶，协调细胞对环境变化的反应并影响细胞命运、分化和存活。ASK1 是细胞凋亡的关键参与者，可促进线粒体依赖性 caspase 激活。ASK1 Protein, Human (His) 是重组的 ASK1 蛋白，由 E. coli 表达，带有 C-6*His 标签。ASK1 Protein, Human (His) 全长 298 个氨基酸。

HY-P702662

	MAPKAPK2 Protein, Human (323a.a) MAPKAPK2; mitogen-activated protein kinase-activated protein kinase 2; MAP kinase-activated protein kinase 2; MAPKAP kinase 2; MAPK-activated protein kinase 2; MK2; MK-2; MAPKAP-K2	Human	E. coli
	MAPKAPK2 蛋白是一种应激激活激酶，参与多种细胞过程，包括细胞因子产生、胞吞作用、细胞骨架重组、细胞迁移、细胞周期控制、染色质重塑、DNA 损伤反应和转录调节。MAPKAPK2 Protein, Human (323a.a) 是重组的 MAPKAPK2 蛋白，由 E. coli 表达，带有 tag Free 标签。MAPKAPK2 Protein, Human (323a.a)

HY-P701680

	ERK3 Protein, Human (His) MAPK6; mitogen-activated protein kinase 6; MAP kinase 6; MAPK 6; Extracellular signal-regulated kinase 3; ERK-3; MAP kinase isoform p97; p97-MAPK	Human	E. coli
	ERK3 蛋白是一种非典型 MAPK，磷酸化 MAP2 和 MAPKAPK5。ERK3/MAPK6 与 MAPKAPK5 相互作用，发生 Ser-189 磷酸化，促进 MAPKAPK5 激活。激活的 MAPKAPK5 会相互磷酸化 ERK3/MAPK6。该复合物的精确功能意义，特别是在细胞周期进入方面，仍然难以捉摸。ERK3 Protein, Human (His) 是重组的 ERK3 蛋白，由 E. coli 表达，带有 N-6*His 标签。ERK3 Protein, Human (His) 全长 319 个氨基酸。

HY-P702735

	MAPK1 Protein, Human (Flag, His) MAPK1; mitogen-activated protein kinase 1; PRKM1, PRKM2; ERK; ERK2; MAPK2; p41mapk; ERK-2; MAPK 2; p42-MAPK; MAP kinase 1; MAP kinase 2; MAP kinase isoform p42; protein tyrosine kinase ERK2; mitogen-activated protein kinase 2; extracellular signal-regulated kinase 2; p38; p40; p41; ERT1; PRKM1; PRKM2; P42MAPK	Human	E. coli

HY-P701803

	MAPK4 Protein, Human (Sf9, His, GST) MAPK4; mitogen-activated protein kinase 4; MAP kinase 4; MAPK 4; Extracellular signal-regulated kinase 4; ERK-4; MAP kinase isoform p63; p63-MAPK	Human	Sf9 insect cells
	MAPK4 是一种非典型 MAPK 蛋白，可磷酸化微管相关蛋白 2 (MAP2) 和 MAPKAPK5，形成具有复杂磷酸化事件的复合物。与 MAPKAPK5 的相互作用导致 ERK3/MAPK6 在 Ser-189 处磷酸化，从而激活 MAPKAPK5，从而相互磷酸化 ERK3/MAPK6。这种相互作用的具体细胞作用虽然尚不清楚，但表明 ERK3 可能参与促进进入细胞周期。MAPK4 Protein, Human (Sf9, His, GST) 是重组的 MAPK4 蛋白，由 Sf9 insect cells 表达，带有 N-8*His, N-GST 标签。MAPK4 Protein, Human (Sf9, His, GST) 全长 586 个氨基酸。

HY-P74748

	MKK6 Protein, Human (S207D, T211D, sf9) Dual specificity mitogen-activated protein kinase kinase 6; MAPKK 6; MEK 6; SAPKK3; MAP2K6	Human	Sf9 insect cells
	MKK6 蛋白是参与 MAP 激酶途径的双特异性激酶。MKK6 Protein, Human (S207D, T211D, sf9) 是重组的 MKK6 蛋白，由 Sf9 insect cells 表达，不带标签。MKK6 Protein, Human (S207D, T211D, sf9) 全长 334 个氨基酸，分子量约为 ~38 kDa。

HY-P701801

	MAP4K6 Protein, Human (Sf9, GST) MINK1; Misshapen-like kinase 1; GCK family kinase MiNK; MAPK/ERK kinase kinase kinase 6; MEK kinase kinase 6; MEKKK 6; Misshapen/NIK-related kinase; mitogen-activated protein kinase kinase kinase kinase 6	Human	Sf9 insect cells
	MAP4K6 蛋白是一种关键的丝氨酸/苏氨酸激酶，可负向调节 Ras 相关的 Rap2 介导的信号传导，影响神经元结构和 AMPA 受体运输。它在调节海马神经元突触密度、树突复杂性和表面 AMPA 受体表达方面的重要作用凸显了其重要性。MAP4K6 Protein, Human (Sf9, GST) 是重组的 MAP4K6 蛋白，由 Sf9 insect cells 表达，带有 N-GST 标签。MAP4K6 Protein, Human (Sf9, GST) 全长 314 个氨基酸。

HY-P702934

	MAPK15 Protein, Human (sf9, GST, StrepII) mitogen-activated protein kinase 15 Curated; MAPK 15; Extracellular signal-regulated kinase 7 (ERK-7); Extracellular signal-regulated kinase 8 (ERK-8); MAPK15 Imported; ERK7 By similarity	Human	Sf9 insect cells
	MAPK15 Protein, Human (sf9, GST, StrepII) 是重组的 MAPK15 蛋白，由 Sf9 insect cells 表达，带有 C-Strep, N-GST 标签。MAPK15 Protein, Human (sf9, GST, StrepII)

HY-P701639

	TAB1 Protein, Human (His) TAB1; TGF-beta-activated kinase 1 and MAP3K7-binding protein 1; mitogen-activated protein kinase kinase kinase 7-interacting protein 1; TGF-beta-activated kinase 1-binding protein 1; TAK1-binding protein 1	Human	E. coli
	TAB1 蛋白是响应 TLR 和细胞因子刺激而激活 JNK、NF-kappa-B 和促炎细胞因子的关键接头。它与 MAP3K7/TAK1 结合，诱导自身磷酸化和完全激活。TAB1 Protein, Human (His) 是重组的 TAB1 蛋白，由 E. coli 表达，带有 N-6*His 标签。TAB1 Protein, Human (His) 全长 370 个氨基酸。

HY-P701640

	TAB1 Protein, Human TAB1; TGF-beta-activated kinase 1 and MAP3K7-binding protein 1; mitogen-activated protein kinase kinase kinase 7-interacting protein 1; TGF-beta-activated kinase 1-binding protein 1; TAK1-binding protein 1	Human	E. coli
	TAB1 蛋白是响应 TLR 和细胞因子刺激而激活 JNK、NF-kappa-B 和促炎细胞因子的关键接头。它与 MAP3K7/TAK1 结合，诱导自身磷酸化和完全激活。TAB1 Protein, Human 是重组的 TAB1 蛋白，由 E. coli 表达，不带标签。TAB1 Protein, Human 全长 370 个氨基酸。

HY-P701790

	JNK3 Protein, Human MAPK10; mitogen-activated protein kinase 10; MAP kinase 10; MAPK 10; MAP kinase p49 3F12; Stress-activated protein kinase 1b; SAPK1b; Stress-activated protein kinase JNK3; c-Jun N-terminal kinase 3	Human	E. coli
	JNK3 是神经元过程中关键的丝氨酸/苏氨酸蛋白激酶，调节增殖、分化、迁移和凋亡。通过 MAP2K4/MKK4 和 MAP2K7/MKK7 激活会导致 JNK3 磷酸化，进而磷酸化 AP-1 成分（如 JUN 和 ATF2），从而调节 AP-1 转录活性。JNK3 Protein, Human 是重组的 JNK3 蛋白，由 E. coli 表达，不带标签。JNK3 Protein, Human 全长 423 个氨基酸。

HY-P701791

	JNK3 Protein, Human (His) MAPK10; mitogen-activated protein kinase 10; MAP kinase 10; MAPK 10; MAP kinase p49 3F12; Stress-activated protein kinase 1b; SAPK1b; Stress-activated protein kinase JNK3; c-Jun N-terminal kinase 3	Human	E. coli
	JNK3 是神经元过程中关键的丝氨酸/苏氨酸蛋白激酶，调节增殖、分化、迁移和凋亡。通过 MAP2K4/MKK4 和 MAP2K7/MKK7 激活会导致 JNK3 磷酸化，进而磷酸化 AP-1 成分（如 JUN 和 ATF2），从而调节 AP-1 转录活性。JNK3 Protein, Human (His) 是重组的 JNK3 蛋白，由 E. coli 表达，带有 N-6*His 标签。JNK3 Protein, Human (His) 全长 423 个氨基酸。

HY-P702663

	MAPKAPK3 Protein, Human (Active, sf9, GST) MAPKAPK3; mitogen-activated protein kinase-activated protein kinase 3; MAP kinase-activated protein kinase 3; 3pK; 3PK; MAPKAP3; MAPKAP kinase 3; chromosome 3p kinase; MAPK-activated protein kinase 3; MK-3; MAPKAP-K3; MAPKAPK-3	Human	Sf9 insect cells
	MAPKAPK3 蛋白是一种应激激活激酶，参与多种细胞过程，包括细胞因子产生和内吞作用。它在应激过程中被 p38-alpha/MAPK14 磷酸化，靶向特定底物，与 MAPKAPK2 相似，但活性较低。MAPKAPK3 Protein, Human (Active, sf9, GST) 是重组的 MAPKAPK3 蛋白，由 Sf9 insect cells 表达，带有 GST 标签。MAPKAPK3 Protein, Human (Active, sf9, GST)

HY-P700589

	MAP2K4 Protein, Human (P. pastoris, His-GST) MAP2K4; mitogen-activated protein kinase kinase 4; SERK1; dual specificity mitogen-activated protein kinase kinase 4; JNKK1; MEK4; MKK4; PRKMK4; MEK 4; MAPKK 4; SAPK kinase 1; MAPK/ERK kinase 4; SAPK/ERK kinase 1; MAP kinase kinase 4; JNK-activated kinase 1; JNK activating kinase 1; JNK-activating kinase 1; c-Jun N-terminal kinase kinase 1; stress-activated protein kinase kinase 1; JNKK; SEK1; MAPKK4; SAPKK1; SAPKK-1	Human	P. pastoris
	MAP2K4 蛋白是参与 MAP 激酶途径的双特异性激酶。MAP2K4 Protein, Human (P. pastoris, His-GST) 是重组的 MAP2K4 蛋白，由 P. pastoris 表达，带有 N-6*His, N-GST 标签。MAP2K4 Protein, Human (P. pastoris, His-GST) 全长 398 个氨基酸，分子量为 71.5 kDa。

HY-P702841

	MAP2K4 Protein, Human (Sf9) MAP2K4; mitogen-activated protein kinase kinase 4; SERK1; dual specificity mitogen-activated protein kinase kinase 4; JNKK1; MEK4; MKK4; PRKMK4; MEK 4; MAPKK 4; SAPK kinase 1; MAPK/ERK kinase 4; SAPK/ERK kinase 1; MAP kinase kinase 4; JNK-activated kinase 1; JNK activating kinase 1; JNK-activating kinase 1; c-Jun N-terminal kinase kinase 1; stress-activated protein kinase kinase 1; JNKK; SEK1; MAPKK4; SAPKK1; SAPKK-1	Human	Sf9 insect cells
	MAP2K4 蛋白是参与 MAP 激酶途径的双特异性激酶。MAP2K4 Protein, Human (Sf9) 是重组的 MAP2K4 蛋白，由 Sf9 insect cells 表达，不带标签。

HY-P701678

	ERK1 Protein, Human (GST) MAPK3; mitogen-activated protein kinase 3; MAP kinase 3; MAPK 3; ERT2; Extracellular signal-regulated kinase 1; ERK-1; Insulin-stimulated MAP2 kinase; MAP kinase isoform p44; p44-MAPK; Microtubule-associated protein 2 kinase; p44-ERK1	Human	E. coli
	ERK1蛋白是MAP激酶途径中重要的丝氨酸/苏氨酸激酶，与MAPK1/ERK2配合激活MAPK/ERK级联。在 KIT 和 KITLG/SCF 的刺激下，该通路在细胞生长、粘附、存活和分化中发挥着关键作用。ERK1 Protein, Human (GST) 是重组的 ERK1 蛋白，由 E. coli 表达，带有 N-GST 标签。ERK1 Protein, Human (GST) 全长 378 个氨基酸。

HY-P703250

	MAP4K3 Protein, Human (Sf9, GST, Flag) mitogen-activated protein kinase kinase kinase kinase 3; Germinal center kinase-related protein kinase; GLK; MAPK/ERK kinase kinase kinase 3; MEK kinase kinase 3; MEKKK 3; MAP4K3; RAB8IPL1; Homo sapiens; Human; GLK; kinase; Serine/threonine-protein kinase; Transferase; 2.7.11.1	Human	Sf9 insect cells
	MAP4K3 Protein, Human (Sf9, GST, Flag) 是重组的 MAP4K3 蛋白，由 Sf9 insect cells 表达，带有 GST, Flag 标签。MAP4K3 Protein, Human (Sf9, GST, Flag)

HY-P701798

	MAP2K7 Protein, Human (Sf9) MAP2K7; Dual specificity mitogen-activated protein kinase kinase 7; MAP kinase kinase 7; MAPKK 7; JNK-activating kinase 2; MAPK/ERK kinase 7; MEK 7; Stress-activated protein kinase kinase 4; SAPK kinase 4; SAPKK-4; SAPKK4; c-Jun N-terminal kinase kinase 2; JNK kinase 2; JNKK 2	Human	Sf9 insect cells
	MAP2K7 蛋白是参与 MAP 激酶信号转导途径的双特异性激酶。MAP2K7 Protein, Human (Sf9) 是重组的 MAP2K7 蛋白，由 Sf9 insect cells 表达，不带标签。MAP2K7 Protein, Human (Sf9) 全长 418 个氨基酸。

HY-P701799

	MAP2K7 Protein, Human (Sf9, His, GST) MAP2K7; Dual specificity mitogen-activated protein kinase kinase 7; MAP kinase kinase 7; MAPKK 7; JNK-activating kinase 2; MAPK/ERK kinase 7; MEK 7; Stress-activated protein kinase kinase 4; SAPK kinase 4; SAPKK-4; SAPKK4; c-Jun N-terminal kinase kinase 2; JNK kinase 2; JNKK 2	Human	Sf9 insect cells
	MAP2K7 蛋白是参与 MAP 激酶信号转导途径的双特异性激酶。MAP2K7 Protein, Human (Sf9, His, GST) 是重组的 MAP2K7 蛋白，由 Sf9 insect cells 表达，带有 N-8*His, N-GST 标签。MAP2K7 Protein, Human (Sf9, His, GST) 全长 418 个氨基酸。

产品对比


产品	In-stock - + Add to Cart
货号
种属
表达系统
标签
蛋白编号
基因 ID
分子量
纯度
内毒素含量
生物活性
性状
组分
保存条件 & 期限
运输条件
Free Sample	Yes No
规格	*该产品已“停产”。等效替代： / In-stock - + Add to Cart 询价

Cat. No.	Compare	Product Name	Application	Reactivity

HY-P80908

	TAK1 Antibody (YA663) MAP3K7; TAK1; mitogen-activated protein kinase kinase kinase 7; Transforming growth factor-beta-activated kinase 1; TGF-beta-activated kinase 1	WB	Human, Mouse, Rat, Monkey
	TAK1 Antibody (YA663) is a non-conjugated and Mouse origined monoclonal antibody about 67 kDa, targeting to TAK1 (3G1). It can be used for WB assays with tag free, in the background of Human, Mouse, Rat, Monkey.

HY-P80858

	Phospho-TAK1 (Ser439) Antibody MAP3K7; TAK1; mitogen-activated protein kinase kinase kinase 7; Transforming growth factor-beta-activated kinase 1; TGF-beta-activated kinase 1	WB, ICC/IF, IP	Human, Mouse, Rat
	Phospho-TAK1 (Ser439) Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 67 kDa, targeting to Phospho-TAK1 (Ser439). It can be used for WB,ICC/IF,IP assays with tag free, in the background of Human, Mouse, Rat.

HY-P80792

	Phospho-ASK1 (Ser966) Antibody MAP3K5; ASK1; MAPKKK5; MEKK5; mitogen-activated protein kinase kinase kinase 5; Apoptosis signal-regulating kinase 1; ASK-1; MAPK/ERK kinase kinase 5; MEK kinase 5; MEKK 5	WB, IHC-P	Human, Mouse, Rat
	Phospho-ASK1 (Ser966) Antibody is a non-conjugated and Rabbit origined polyclonal antibody about 155 kDa, targeting to Phospho-ASK1 (Ser966). It can be used for WB,IHC-P assays with tag free, in the background of Human, Mouse, Rat.

HY-P83470

	MEKK2 Antibody (YA3215) MAP3K2; MAPKKK2; MEKK2; mitogen-activated protein kinase kinase kinase 2; MAPK/ERK kinase kinase 2; MEK kinase 2; MEKK 2	WB, ICC/IF, IP	Human, Mouse, Rat
	MEKK2 Antibody (YA3215) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA3215), targeting MEKK2, with a predicted molecular weight of 70 kDa (observed band size: 72 kDa). MEKK2 Antibody (YA3215) can be used for WB, ICC/IF, IP experiment in human, mouse, rat background.

HY-P83469

	MEK3 Antibody (YA3214) AW212142; dual specificity mitogen activated protein kinase kinase 3; Dual specificity mitogen activated protein kinase kinase 6; Dual specificity mitogen-activated protein kinase kinase 3; MAP kinase kinase 3; MAP kinase kinase 6; map2k3; MAP2K6; MAPK ERK kinase 3; MAPK/ERK kinase 3; MAPK/ERK kinase 6; MAPKK 3; MAPKK 6; MAPKK3; MAPKK6; MEK 3; MEK 6; MEK3; mitogen activated protein kinase kinase 3; mitogen activated protein kinase kinase 6; MKK 3; MKK3; MKK6; mMKK3b; MP2K3_HUMAN; PRKMK 3; PRKMK3; PRKMK6; protein kinase; mitogen activated; kinase 6 (MAP kinase kinase 6); protein kinase; mitogen-activated; kinase 3; SAPK kinase 2; SAPKK 2; SAPKK 3; SAPKK-2; SAPKK2; SAPKK3; Stress activated protein kinase kinase 2; Stress activated protein kinase kinase 3; Stress-activated protein kinase kinase 2.	WB, ICC/IF, IP	Human, Mouse, Rat
	MEK3 Antibody (YA3214) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA3214), targeting MEK3, with a predicted molecular weight of 39 kDa (observed band size: 38-40 kDa). MEK3 Antibody (YA3214) can be used for WB, ICC/IF, IP experiment in human, mouse, rat background.

HY-P83492

	MLK3 Antibody (YA3237) MAP3K11; MLK3; PTK1; SPRK; mitogen-activated protein kinase kinase kinase 11; Mixed lineage kinase 3; Src-homology 3 domain-containing proline-rich kinase	WB, ICC/IF	Human
	MLK3 Antibody (YA3237) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA3237), targeting MLK3, with a predicted molecular weight of 93 kDa (observed band size: 93 kDa). MLK3 Antibody (YA3237) can be used for WB, ICC/IF experiment in human background.

HY-P80549

	ASK1 Antibody MAP3K5; ASK1; MAPKKK5; MEKK5; mitogen-activated protein kinase kinase kinase 5; Apoptosis signal-regulating kinase 1; ASK-1; MAPK/ERK kinase kinase 5; MEK kinase 5; MEKK 5	WB, IHC-P, ICC/IF, FC	Human, Mouse
	ASK1 Antibody is a non-conjugated and Rabbit origined polyclonal antibody about 155 kDa, targeting to ASK1. It can be used for WB,IHC-P,ICC/IF,FC assays with tag free, in the background of Human, Mouse.

HY-P83395

	MEK5 Antibody (YA3140) MAP2K5; MEK5; MKK5; PRKMK5; Dual specificity mitogen-activated protein kinase kinase 5; MAP kinase kinase 5; MAPKK 5; MAPK/ERK kinase 5; MEK 5	WB, ICC/IF	Human
	MEK5 Antibody (YA3140) is a biotin-conjugated non-conjugated IgG antibody, targeting MEK5, with a predicted molecular weight of 50 kDa. MEK5 Antibody (YA3140) can be used for WB, ICC/IF experiment in human background.

HY-P81378

	MAP4K4/NIK Antibody (YA1123) MAP4K4; HGK, KIAA0687, NIK; mitogen-activated protein kinase kinase kinase kinase 4; HPK/GCK-like kinase HGK; MAPK/ERK kinase kinase kinase 4 (MEK kinase kinase 4; MEKKK 4); Nck-interacting kinase	IHC-P	Human
	MAP4K4/NIK Antibody (YA1123) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1123), targeting MAP4K4/NIK. MAP4K4/NIK Antibody (YA1123) can be used for IHC-P experiment in human background.

HY-P83314

	MEK2 Antibody (YA3059) MAP2K2; MEK2; MKK2; PRKMK2; Dual specificity mitogen-activated protein kinase kinase 2; MAP kinase kinase 2; MAPKK 2; ERK activator kinase 2; MAPK/ERK kinase 2; MEK 2	WB, IHC-F, IHC-P, ICC/IF, IP	Human, Mouse
	MEK2 Antibody (YA3059) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA3059), targeting MEK2, with a predicted molecular weight of 44 kDa (observed band size: 44 kDa). MEK2 Antibody (YA3059) can be used for WB, IHC-F, IHC-P, ICC/IF, IP experiment in human, mouse background.

HY-P83405

	JNK3 Antibody (YA3150) mitogen-activated protein kinase 10; MAP kinase 10; MAPK 10; MAP kinase p49 3F12; Stress-activated protein kinase 1b; SAPK1b; MAPK10; JNK3; JNK3A; PRKM10; SAPK1B	WB, ICC/IF, FC	Human, Mouse, Rat
	JNK3 Antibody (YA3150) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA3150), targeting JNK3, with a predicted molecular weight of 53 kDa (observed band size: 53 kDa). JNK3 Antibody (YA3150) can be used for WB, ICC/IF, FC experiment in human, mouse, rat background.

HY-P80777

	p38 Antibody MAPK14; CSBP; CSBP1; CSBP2; CSPB1; MXI2; SAPK2A; mitogen-activated protein kinase 14; MAP kinase 14; MAPK 14; Cytokine suppressive anti-inflammatory drug-binding protein; CSAID-binding protein; CSBP; MAP kinase MXI2; MAX-interacting protein	WB, IP	Human
	p38 Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 41 kDa, targeting to p38. It can be used for WB,IP assays with tag free, in the background of Human.

HY-P80832

	Phospho-MEK1 (Ser298) Antibody MAP2K1; MEK1; PRKMK1; Dual specificity mitogen-activated protein kinase kinase 1; MAP kinase kinase 1; MAPKK 1; MKK1; ERK activator kinase 1; MAPK/ERK kinase 1; MEK 1	WB, ICC/IF	Human, Mouse, Rat
	Phospho-MEK1 (Ser298) Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 43 kDa, targeting to Phospho-MEK1 (Ser298). It can be used for WB,ICC/IF assays with tag free, in the background of Human, Mouse, Rat.

HY-P80833

	Phospho-MEK1 (Thr292) Antibody MAP2K1; MEK1; PRKMK1; Dual specificity mitogen-activated protein kinase kinase 1; MAP kinase kinase 1; MAPKK 1; MKK1; ERK activator kinase 1; MAPK/ERK kinase 1; MEK 1	WB	Mouse, Rat
	Phospho-MEK1 (Thr292) Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 43 kDa, targeting to Phospho-MEK1 (Thr292). It can be used for WB assays with tag free, in the background of Mouse, Rat.

HY-P80776

	p38 Antibody (YA696) MAPK14; CSBP; CSBP1; CSBP2; CSPB1; MXI2; SAPK2A; mitogen-activated protein kinase 14; MAP kinase 14; MAPK 14; Cytokine suppressive anti-inflammatory drug-binding protein; CSAID-binding protein; CSBP; MAP kinase MXI2; MAX-interacting protein	WB	Human, Mouse, Rat, Monkey
	p38 Antibody (YA696) is a non-conjugated and Mouse origined monoclonal antibody about 41 kDa, targeting to p38 (5A1). It can be used for WB assays with tag free, in the background of Human, Mouse, Rat, Monkey.

HY-P80728

	JNK Antibody AI849689; c Jun N terminal kinase 1; C-JUN kinase 1; c-Jun N-terminal kinase 1; EC 2.7.11.24; JAK 1A; JAK1A; JNK 1; JNK 46; JNK; JNK-46; JNK1A2; JNK21B1/2; MAP kinase 8; MAPK 8; MAPK8; mitogen activated protein kinase 8; mitogen-activated protein kinase 8	WB, IP	Human, Mouse, Rat, Hamster
	JNK Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 48 kDa, targeting to JNK. It can be used for WB,IP assays with tag free, in the background of Human, Mouse, Rat, Hamster.

HY-P80776A

	Phospho-p38 (Thr180+Tyr182) Antibody p38 (phospho T180 + Y182); p-p38 (phospho T180 + Y182); p38 (phospho T180/Y182); CSAID Binding protein 1; CSAID binding protein; CSAID-binding protein; Csaids binding protein; CSBP 1; CSBP 2; CSBP; CSBP1; CSBP2; CSPB 1; CSPB1; Cytokine suppressive anti inflammatory drug binding protein; Cytokine suppressive anti-inflammatory drug-binding protein; EXIP; MAP kinase 14; MAP kinase MXI2; MAP kinase p38 alpha; MAPK 14; MAPK14; MAX interacting protein 2; MAX-interacting protein 2; mitogen activated protein kinase 14; mitogen activated protein kinase p38 alpha; mitogen-activated protein kinase 14; mitogen-activated protein kinase p38 alpha; MK14_HUMAN; Mxi 2; Mxi2; p38 ALPHA; p38; p38 MAP kinase; p38 MAPK; p38 mitogen activated protein kinase; p38ALPHA; p38alpha Exip; PRKM14; PRKM15; RK; SAPK 2A; SAPK2A; Stress activated protein kinase 2A.	WB, IHC-P, FC, ICC/IF, ELISA	Human, Mouse
	Phospho-p38 (Thr180+Tyr182) Antibody is a rabbit-derived non-conjugated IgG antibody, targeting Phospho-p38 (Thr180+Tyr182), with a predicted molecular weight of 41 kDa . Phospho-p38 (Thr180+Tyr182) Antibody can be used for WB, IHC-P, FC, ICC/IF, ELISA experiments in human, mouse backgrounds.

HY-P80645

	DUSP1 Antibody DUSP1; CL100; MKP1; PTPN10; VH1; Dual specificity protein phosphatase 1; Dual specificity protein phosphatase hVH1; mitogen-activated protein kinase phosphatase 1; MAP kinase phosphatase 1; MKP-1; protein-tyrosine phosphatase CL100	WB, IHC-P, ICC/IF, IP, FC	Human, Mouse, Rat
	DUSP1 Antibody is a non-conjugated and Rabbit origined polyclonal antibody about 39 kDa, targeting to DUSP1. It can be used for WB,IHC-P,ICC/IF,IP,FC assays with tag free, in the background of Human, Mouse, Rat.

HY-P80842

	Phospho-p38 (Thr180/Tyr182) Antibody MAPK14; CSBP; CSBP1; CSBP2; CSPB1; MXI2; SAPK2A; mitogen-activated protein kinase 14; MAP kinase 14; MAPK 14; Cytokine suppressive anti-inflammatory drug-binding protein; CSAID-binding protein; CSBP; MAP kinase MXI2; MAX-interacting protein	WB	Human, Mouse, Rat
	Phospho-p38 (Thr180/Tyr182) Antibody is a non-conjugated and Rabbit origined polyclonal antibody about 41 kDa, targeting to Phospho-p38 (Thr180/Tyr182). It can be used for WB assays with tag free, in the background of Human, Mouse, Rat.

HY-P81343

	MAP2K6 Antibody (YA1088) MAP2K6; MEK6; MKK6; PRKMK6; SKK3; Dual specificity mitogen-activated protein kinase kinase 6; MAP kinase kinase 6; MAPKK 6; MAPK/ERK kinase 6; MEK 6; Stress-activated protein kinase kinase 3; SAPK kinase 3; SAPKK-3; SAPKK3	WB, IP	Human, Rat
	MAP2K6 Antibody (YA1088) is a mouse-derived non-conjugated IgG1 antibody (Clone NO.: YA1088), targeting MAP2K6, with a predicted molecular weight of 37 kDa (observed band size: 40 kDa). MAP2K6 Antibody (YA1088) can be used for WB, IP experiment in human, rat background.

HY-P80729

	JNK1 Antibody (YA720) AI849689; c Jun N terminal kinase 1; C-JUN kinase 1; c-Jun N-terminal kinase 1; EC 2.7.11.24; JAK 1A; JAK1A; JNK 1; JNK 46; JNK; JNK-46; JNK1A2; JNK21B1/2; MAP kinase 8; MAPK 8; MAPK8; mitogen activated protein kinase 8; mitogen-activated protein kinase 8	WB, ICC/IF	Human, Mouse, Rat
	JNK1 (1A4) Antibody is a non-conjugated and Mouse origined monoclonal antibody about 48 kDa, targeting to JNK1 (1A4). It can be used for WB,ICC/IF assays with tag free, in the background of Human, Mouse, Rat.

HY-P82902

	MEK7 Antibody (YA2647) MAP2K7; JNKK2; MEK7; MKK7; PRKMK7; SKK4; Dual specificity mitogen-activated protein kinase kinase 7; MAP kinase kinase 7; MAPKK 7; JNK-activating kinase 2; MAPK/ERK kinase 7; MEK 7; Stress-activated protein kinase kinase 4; SAPK kinase 4; S	WB, IHC-P, ICC/IF, IP, FC	Human, Mouse, Rat
	MEK7 Antibody (YA2647) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2647), targeting MEK7, with a predicted molecular weight of 47 kDa (observed band size: 47 kDa). MEK7 Antibody (YA2647) can be used for WB, IHC-P, ICC/IF, IP, FC experiment in human, mouse, rat background.

HY-P80831

	Phospho-JNK1 (Thr183/Tyr185) Antibody AI849689; c Jun N terminal kinase 1; C-JUN kinase 1; c-Jun N-terminal kinase 1; EC 2.7.11.24; JAK 1A; JAK1A; JNK 1; JNK 46; JNK; JNK-46; JNK1A2; JNK21B1/2; MAP kinase 8; MAPK 8; MAPK8; mitogen activated protein kinase 8; mitogen-activated protein kinase 8	WB, IP	Human, Rat
	Phospho-JNK1 (Thr183/Tyr185) Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 48 kDa, targeting to Phospho-JNK1 (Thr183/Tyr185). It can be used for WB,IP assays with tag free, in the background of Human, Rat.

HY-P80834

	Phospho-MEK4 (Ser80) Antibody MAP2K4; JNKK1; MEK4; MKK4; PRKMK4; SEK1; SERK1; SKK1; Dual specificity mitogen-activated protein kinase kinase 4; MAP kinase kinase 4; MAPKK 4; JNK-activating kinase 1; MAPK/ERK kinase 4; MEK 4; SAPK/ERK kinase 1; SEK1; Stress-activated pro	WB, IP	Human
	Phospho-MEK4 (Ser80) Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 44 kDa, targeting to Phospho-MEK4 (Ser80). It can be used for WB,IP assays with tag free, in the background of Human.

HY-P82888

	MEKK3 Antibody (YA2633) MAP/ERK kinase kinase 3; MAP3K3; MAPK/ERK kinase kinase 3; MAPKKK3; MEK kinase 3; MEKK 3; MEKK3; mitogen activated protein kinase kinase kinase 3	WB, IHC-P, ICC/IF, IP, FC	Human, Mouse, Rat
	MEKK3 Antibody (YA2633) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2633), targeting MEKK3, with a predicted molecular weight of 71 kDa (observed band size: 71 kDa). MEKK3 Antibody (YA2633) can be used for WB, IHC-P, ICC/IF, IP, FC experiment in human, mouse, rat background.

产品对比


产品	In-stock - + Add to Cart
货号
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反应物种
应用
推荐稀释比例
分子量
偶联
克隆性
免疫原
性状
同型
基因 ID
蛋白数据库
纯度
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