786-0
|
IC50 |
0.63 μM
Compound: chidamide
|
Antiproliferative activity against human 786-O cells incubated for 72 hrs by luminescence assay
Antiproliferative activity against human 786-O cells incubated for 72 hrs by luminescence assay
|
[PMID: 34954594]
|
A549
|
IC50 |
2.79 μM
Compound: chidamide
|
Antiproliferative activity against human A549 cells incubated for 72 hrs by luminescence assay
Antiproliferative activity against human A549 cells incubated for 72 hrs by luminescence assay
|
[PMID: 34954594]
|
CCRF-CEM
|
IC50 |
0.63 μM
Compound: Chidamide
|
Cytotoxicity against human CCRF-CEM cells by MTT assay
Cytotoxicity against human CCRF-CEM cells by MTT assay
|
[PMID: 31078410]
|
CCRF-CEM
|
IC50 |
0.83 μM
Compound: chidamide
|
Antiproliferative activity against human CCRF-CEM cells incubated for 72 hrs by luminescence assay
Antiproliferative activity against human CCRF-CEM cells incubated for 72 hrs by luminescence assay
|
[PMID: 34954594]
|
CCRF-CEM
|
IC50 |
|
Cytotoxicity against human CCRF-CEM cells measured after 72 hrs by MTT assay
Cytotoxicity against human CCRF-CEM cells measured after 72 hrs by MTT assay
|
[PMID: 34986303]
|
COLO-678
|
IC50 |
> 10 μM
Compound: chidamide
|
Antiproliferative activity against human COLO-678 cells incubated for 72 hrs by luminescence assay
Antiproliferative activity against human COLO-678 cells incubated for 72 hrs by luminescence assay
|
[PMID: 34954594]
|
CWR22R
|
IC50 |
1.08 μM
Compound: chidamide
|
Antiproliferative activity against human 22Rv1 cells incubated for 72 hrs by luminescence assay
Antiproliferative activity against human 22Rv1 cells incubated for 72 hrs by luminescence assay
|
[PMID: 34954594]
|
DOHH-2
|
IC50 |
0.53 μM
Compound: chidamide
|
Antiproliferative activity against human DOHH-2 cells incubated for 72 hrs by luminescence assay
Antiproliferative activity against human DOHH-2 cells incubated for 72 hrs by luminescence assay
|
[PMID: 34954594]
|
EBC-1
|
IC50 |
|
Antiproliferative activity against human EBC1 cells after 72 hrs by SRB assay
Antiproliferative activity against human EBC1 cells after 72 hrs by SRB assay
|
[PMID: 28835797]
|
HCT-116
|
IC50 |
> 20 μM
Compound: 1; CS055, HBI-8000
|
Antiproliferative activity against human HCT116 cells NAMPT deficient assessed as reduction in cell viability after 72 hrs by CCK8 assay
Antiproliferative activity against human HCT116 cells NAMPT deficient assessed as reduction in cell viability after 72 hrs by CCK8 assay
|
[PMID: 31938461]
|
HCT-116
|
IC50 |
0.34 μM
Compound: 1; CS055, HBI-8000
|
Antiproliferative activity against human HCT116 cells assessed as reduction in cell viability after 72 hrs by CCK8 assay
Antiproliferative activity against human HCT116 cells assessed as reduction in cell viability after 72 hrs by CCK8 assay
|
[PMID: 31938461]
|
HCT-116
|
IC50 |
1.09 μM
Compound: HBI-8000; CS055
|
Antiproliferative activity against human HCT116 assessed as reduction in cell viability measured after 72 hrs using alamar blue based fluorescence method
Antiproliferative activity against human HCT116 assessed as reduction in cell viability measured after 72 hrs using alamar blue based fluorescence method
|
[PMID: 30802729]
|
HCT-116
|
IC50 |
2.08 μM
Compound: Chidamide
|
Antiproliferative activity against human HCT-116 cells assessed as inhibition of cell growth incubated for 72 hrs by luminescence based analysis
Antiproliferative activity against human HCT-116 cells assessed as inhibition of cell growth incubated for 72 hrs by luminescence based analysis
|
[PMID: 35649291]
|
HCT-116
|
IC50 |
2.08 μM
Compound: chidamide
|
Antiproliferative activity against human HCT-116 cells incubated for 72 hrs by luminescence assay
Antiproliferative activity against human HCT-116 cells incubated for 72 hrs by luminescence assay
|
[PMID: 34954594]
|
HCT-116
|
IC50 |
2.082 μM
Compound: Chidamide
|
Antiproliferative activity against human HCT-116 cells assessed as cell viability at 1 uM incubated for 72 hrs by luminescence assay
Antiproliferative activity against human HCT-116 cells assessed as cell viability at 1 uM incubated for 72 hrs by luminescence assay
|
[PMID: 34995925]
|
HCT-116
|
IC50 |
|
Antiproliferative activity against human HCT116 cells after 72 hrs by SRB assay
Antiproliferative activity against human HCT116 cells after 72 hrs by SRB assay
|
[PMID: 28835797]
|
HEL
|
IC50 |
0.013 μM
Compound: 1; CS055, HBI-8000
|
Antiproliferative activity against human HEL cells assessed as reduction in cell viability after 72 hrs by CCK8 assay
Antiproliferative activity against human HEL cells assessed as reduction in cell viability after 72 hrs by CCK8 assay
|
[PMID: 31938461]
|
HEL
|
IC50 |
1.8 μM
Compound: 1; CS055, HBI-8000
|
Antiproliferative activity against human HEL cells NAMPT deficient assessed as reduction in cell viability after 72 hrs by CCK8 assay
Antiproliferative activity against human HEL cells NAMPT deficient assessed as reduction in cell viability after 72 hrs by CCK8 assay
|
[PMID: 31938461]
|
HeLa
|
IC50 |
7.16 μM
Compound: CS055, Epidaza
|
Inhibition of HDAC in human HeLa cell extract incubated for 1 hr by colorimetric activity assay
Inhibition of HDAC in human HeLa cell extract incubated for 1 hr by colorimetric activity assay
|
10.1039/C4MD00350K
|
HepG2
|
IC50 |
|
Antiproliferative activity against human HepG2 cells assessed as inhibition of cell growth incubated for 72 hrs by luminescence based analysis
Antiproliferative activity against human HepG2 cells assessed as inhibition of cell growth incubated for 72 hrs by luminescence based analysis
|
[PMID: 35649291]
|
HepG2
|
IC50 |
|
Antiproliferative activity against human HepG2 cells measured after 48 hrs by MTT assay
Antiproliferative activity against human HepG2 cells measured after 48 hrs by MTT assay
|
[PMID: 31053508]
|
HL-60
|
IC50 |
0.0022 μM
Compound: 1; CS055, HBI-8000
|
Antiproliferative activity against human HL60 cells assessed as reduction in cell viability after 72 hrs by CCK8 assay
Antiproliferative activity against human HL60 cells assessed as reduction in cell viability after 72 hrs by CCK8 assay
|
[PMID: 31938461]
|
HL-60
|
IC50 |
1.97 μM
Compound: HBI-8000; CS055
|
Antiproliferative activity against human HL60 assessed as reduction in cell viability measured after 72 hrs using alamar blue based fluorescence method
Antiproliferative activity against human HL60 assessed as reduction in cell viability measured after 72 hrs using alamar blue based fluorescence method
|
[PMID: 30802729]
|
HL-60
|
IC50 |
3.2 μM
Compound: 1; CS055, HBI-8000
|
Antiproliferative activity against human HL60 cells NAMPT deficient assessed as reduction in cell viability after 72 hrs by CCK8 assay
Antiproliferative activity against human HL60 cells NAMPT deficient assessed as reduction in cell viability after 72 hrs by CCK8 assay
|
[PMID: 31938461]
|
HT-29
|
IC50 |
6.04 μM
Compound: chidamide
|
Antiproliferative activity against human HT-29 cells incubated for 72 hrs by luminescence assay
Antiproliferative activity against human HT-29 cells incubated for 72 hrs by luminescence assay
|
[PMID: 34954594]
|
HuT78
|
IC50 |
2.42 μM
Compound: chidamide
|
Antiproliferative activity against human HuT78 cells incubated for 72 hrs by luminescence assay
Antiproliferative activity against human HuT78 cells incubated for 72 hrs by luminescence assay
|
[PMID: 34954594]
|
K562
|
IC50 |
0.32 μM
Compound: 1; CS055, HBI-8000
|
Antiproliferative activity against human K562 cells assessed as reduction in cell viability after 72 hrs by CCK8 assay
Antiproliferative activity against human K562 cells assessed as reduction in cell viability after 72 hrs by CCK8 assay
|
[PMID: 31938461]
|
K562
|
IC50 |
0.747 μM
Compound: HBI-8000; CS055
|
Antiproliferative activity against human K562 assessed as reduction in cell viability measured after 72 hrs using alamar blue based fluorescence method
Antiproliferative activity against human K562 assessed as reduction in cell viability measured after 72 hrs using alamar blue based fluorescence method
|
[PMID: 30802729]
|
K562
|
IC50 |
|
Antiproliferative activity against human K562 cells measured after 48 hrs by MTT assay
Antiproliferative activity against human K562 cells measured after 48 hrs by MTT assay
|
[PMID: 31053508]
|
K562
|
IC50 |
1.34 μM
Compound: Chidamide
|
Cytotoxicity against human K562 cells by MTT assay
Cytotoxicity against human K562 cells by MTT assay
|
[PMID: 31078410]
|
K562
|
IC50 |
2.4 μM
Compound: 1; CS055, HBI-8000
|
Antiproliferative activity against human K562 cells NAMPT deficient assessed as reduction in cell viability after 72 hrs by CCK8 assay
Antiproliferative activity against human K562 cells NAMPT deficient assessed as reduction in cell viability after 72 hrs by CCK8 assay
|
[PMID: 31938461]
|
K562
|
IC50 |
8.3 μM
Compound: Chidamide
|
Cytotoxicity against human K562 cells measured after 72 hrs by MTT assay
Cytotoxicity against human K562 cells measured after 72 hrs by MTT assay
|
[PMID: 34986303]
|
MCF7
|
IC50 |
29.07 μM
Compound: HBI-8000; CS055
|
Antiproliferative activity against human MCF7 assessed as reduction in cell viability measured after 72 hrs using alamar blue based fluorescence method
Antiproliferative activity against human MCF7 assessed as reduction in cell viability measured after 72 hrs using alamar blue based fluorescence method
|
[PMID: 30802729]
|
MDA-MB-231
|
IC50 |
9.52 μM
Compound: chidamide
|
Antiproliferative activity against human MDA-MB-231 cells incubated for 72 hrs by luminescence assay
Antiproliferative activity against human MDA-MB-231 cells incubated for 72 hrs by luminescence assay
|
[PMID: 34954594]
|
MDA-MB-468
|
IC50 |
|
Antiproliferative activity against human MDA-MB-468 cells measured after 48 hrs by MTT assay
Antiproliferative activity against human MDA-MB-468 cells measured after 48 hrs by MTT assay
|
[PMID: 31053508]
|
MOLT-4
|
IC50 |
0.75 μM
Compound: chidamide
|
Antiproliferative activity against human MOLT-4 cells incubated for 72 hrs by luminescence assay
Antiproliferative activity against human MOLT-4 cells incubated for 72 hrs by luminescence assay
|
[PMID: 34954594]
|
MV4-11
|
IC50 |
0.783 μM
Compound: Chidamide
|
Antiproliferative activity against human MV4-11 cells assessed as inhibition of cell growth incubated for 72 hrs by luminescence based analysis
Antiproliferative activity against human MV4-11 cells assessed as inhibition of cell growth incubated for 72 hrs by luminescence based analysis
|
[PMID: 35649291]
|
MV4-11
|
IC50 |
|
Antiproliferative activity against human MV4-11 cells measured after 48 hrs by MTT assay
Antiproliferative activity against human MV4-11 cells measured after 48 hrs by MTT assay
|
[PMID: 31053508]
|
NCI-H441
|
IC50 |
2.62 μM
Compound: chidamide
|
Antiproliferative activity against human NCI-H441 cells incubated for 72 hrs by luminescence assay
Antiproliferative activity against human NCI-H441 cells incubated for 72 hrs by luminescence assay
|
[PMID: 34954594]
|
NCI-H460
|
IC50 |
2.34 μM
Compound: chidamide
|
Antiproliferative activity against human NCI-H460 cells incubated for 72 hrs by luminescence assay
Antiproliferative activity against human NCI-H460 cells incubated for 72 hrs by luminescence assay
|
[PMID: 34954594]
|
Rec1
|
IC50 |
1.01 μM
Compound: chidamide
|
Antiproliferative activity against human REC1 cells incubated for 72 hrs by luminescence assay
Antiproliferative activity against human REC1 cells incubated for 72 hrs by luminescence assay
|
[PMID: 34954594]
|
RS4-11
|
IC50 |
0.6 μM
Compound: chidamide
|
Antiproliferative activity against human RS4-11 cells incubated for 72 hrs by luminescence assay
Antiproliferative activity against human RS4-11 cells incubated for 72 hrs by luminescence assay
|
[PMID: 34954594]
|
Sf9
|
IC50 |
|
Inhibition of recombinant full-length human C-terminal FLAG/His-tagged HDAC1 expressed in baculovirus infected Sf9 insect cells using Fluor-de-Lys as substrate measured after 10 mins by fluorescence assay
Inhibition of recombinant full-length human C-terminal FLAG/His-tagged HDAC1 expressed in baculovirus infected Sf9 insect cells using Fluor-de-Lys as substrate measured after 10 mins by fluorescence assay
|
[PMID: 31053508]
|
SK-OV-3
|
IC50 |
8.46 μM
Compound: chidamide
|
Antiproliferative activity against human SK-OV-3 cells incubated for 72 hrs by luminescence assay
Antiproliferative activity against human SK-OV-3 cells incubated for 72 hrs by luminescence assay
|
[PMID: 34954594]
|
SU-DHL-2
|
IC50 |
0.56 μM
Compound: chidamide
|
Antiproliferative activity against human SUDHL2 cells incubated for 72 hrs by luminescence assay
Antiproliferative activity against human SUDHL2 cells incubated for 72 hrs by luminescence assay
|
[PMID: 34954594]
|
TMD8
|
IC50 |
0.48 μM
Compound: chidamide
|
Antiproliferative activity against human TMD8 cells incubated for 72 hrs by luminescence assay
Antiproliferative activity against human TMD8 cells incubated for 72 hrs by luminescence assay
|
[PMID: 34954594]
|
U-937
|
IC50 |
3.3 μM
Compound: Chidamide
|
Cytotoxicity against human U-937 cells measured after 72 hrs by MTT assay
Cytotoxicity against human U-937 cells measured after 72 hrs by MTT assay
|
[PMID: 34986303]
|