1. Gene
  2. BCAS2 - BCAS2 pre-mRNA processing factor Gene

BCAS2 - BCAS2 pre-mRNA processing factor Gene

中文名称:BCAS2 pre-mRNA 加工因子

种属: Homo sapiens

同用名: DAM1; SPF27; Snt309

基因 ID: 10286 | 基因类型: protein coding

关于 BCAS2

Cytogenetic location: 1p13.2 Genomic coordinates (GRCh38): 1:114,567,557-114,581,615 (from NCBI)

This gene has 2 transcripts (splice variants) and 214 orthologues. Ubiquitous expression in bone marrow (RPKM 27.2), brain (RPKM 25.4) and 25 other tissues.

功能概要

通过剪接体参与 mRNA 剪接。位于中心体和核斑点。 U2 型催化步骤 2 剪接体的一部分。与 DNA 复制因子 A 复合物共定位。与乳腺癌有关。 [由基因组资源联盟提供,2022 年 4 月]

Involved in mRNA splicing, via spliceosome. Located in centrosome and nuclear speck. Part of U2-type catalytic step 2 spliceosome. Colocalizes with DNA replication factor A complex. Implicated in breast Cancer. [provided by Alliance of Genome Resources, Apr 2022]

BCAS2 基因产物(1)

mRNA Protein Name
NM_005872.3 NP_005863.1 pre-mRNA-splicing factor SPF27

BCAS2 蛋白结构

BCAS2

BCAS2: Breast carcinoma amplified sequence 2 (BCAS2) (9 - 218)

  • 0
  • 100
  • 200
  • 225 a.a.
蛋白主名 其他名称

pre-mRNA-splicing factor SPF27

DNA amplified in mammary carcinoma 1 protein

BCAS2 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
BCAS2 O75934 ZWINT Homo sapiens O95229
Y2H Array
32296183
种属内
BCAS2 O75934 ZWINT Homo sapiens O95229
Y2H Prey Pooling
32296183
种属内
BCAS2 O75934 ZWINT Homo sapiens O95229
Validated Y2H
32296183
种属内
BCAS2 O75934 KRT40 Homo sapiens Q6A162
Validated Y2H
25416956
种属内
BCAS2 O75934 KRTAP8-1 Homo sapiens Q8IUC2
Validated Y2H
32296183
种属内
BCAS2 O75934 KRTAP8-1 Homo sapiens Q8IUC2
Y2H Array
32296183
种属内
BCAS2 O75934 KRTAP8-1 Homo sapiens Q8IUC2
Y2H Prey Pooling
32296183
种属内
BCAS2 O75934 SPMIP6 Homo sapiens Q8NCR6
Validated Y2H
32296183
种属内
BCAS2 O75934 SPMIP6 Homo sapiens Q8NCR6
Y2H Array
32296183
种属内
BCAS2 O75934 SPMIP6 Homo sapiens Q8NCR6
Y2H Prey Pooling
32296183
种属内
BCAS2 O75934 KRT37 Homo sapiens O76014
Y2H Array
32296183
种属内
BCAS2 O75934 KRT37 Homo sapiens O76014
Validated Y2H
32296183
种属内
BCAS2 O75934 KRT37 Homo sapiens O76014
Y2H Prey Pooling
32296183
种属内
BCAS2 O75934 KRT34 Homo sapiens O76011
Y2H Array
32296183
种属内
BCAS2 O75934 KRT34 Homo sapiens O76011
Validated Y2H
32296183
种属内
BCAS2 O75934 KRT34 Homo sapiens O76011
Y2H Prey Pooling
32296183
种属内
BCAS2 O75934 PLRG1 Homo sapiens O43660
Anti Tag CoIP
33961781
种属内
BCAS2 O75934 PLRG1 Homo sapiens O43660
Anti Tag CoIP
20176811
种属内
BCAS2 O75934 JPH3 Homo sapiens Q8WXH2
Validated Y2H
32814053
种属内
BCAS2 O75934 JPH3 Homo sapiens Q8WXH2
Y2H Array
32814053
种属内
BCAS2 O75934 JPH3 Homo sapiens Q8WXH2
Y2H Pooling
32814053
种属内
BCAS2 O75934 KRT35 Homo sapiens Q92764
Y2H Prey Pooling
32296183
种属内
BCAS2 O75934 KRT35 Homo sapiens Q92764
Validated Y2H
32296183
种属内
BCAS2 O75934 KRT35 Homo sapiens Q92764
Y2H Array
32296183
种属内
BCAS2 O75934 LMO3 Homo sapiens Q8TAP4-4
Y2H Prey Pooling
32296183
种属内
BCAS2 O75934 LMO3 Homo sapiens Q8TAP4-4
Validated Y2H
32296183
种属内
BCAS2 O75934 LMO3 Homo sapiens Q8TAP4-4
Y2H Array
32296183
种属内
BCAS2 O75934 TP53BP2 Homo sapiens Q05BL1
Y2H Prey Pooling
32296183
种属内
BCAS2 O75934 TP53BP2 Homo sapiens Q05BL1
Validated Y2H
32296183
种属内
BCAS2 O75934 TP53BP2 Homo sapiens Q05BL1
Y2H Array
32296183
种属内
BCAS2 O75934 KRT36 Homo sapiens O76013-2
Y2H Prey Pooling
32296183
种属内
BCAS2 O75934 KRT36 Homo sapiens O76013-2
Validated Y2H
32296183
种属内
BCAS2 O75934 KRT36 Homo sapiens O76013-2
Y2H Array
32296183
种属内
BCAS2 O75934 LMO2 Homo sapiens P25791-3
Y2H Array
32296183
种属内
BCAS2 O75934 LMO2 Homo sapiens P25791-3
Y2H Prey Pooling
32296183
种属内
BCAS2 O75934 LMO2 Homo sapiens P25791-3
Validated Y2H
32296183
种属内
BCAS2 O75934 SAXO4 Homo sapiens Q7Z5V6-2
Validated Y2H
32296183
种属内
BCAS2 O75934 CCDC17 Homo sapiens Q96LX7-5
Validated Y2H
32296183
种属内
BCAS2 O75934 KRTAP19-6 Homo sapiens Q3LI70
Y2H Prey Pooling
32296183
种属内
BCAS2 O75934 KRTAP19-6 Homo sapiens Q3LI70
Validated Y2H
32296183
种属内
BCAS2 O75934 KRTAP19-6 Homo sapiens Q3LI70
Y2H Array
32296183
种属内
BCAS2 O75934 IFI35 Homo sapiens P80217-2
Y2H Prey Pooling
32296183
种属内
BCAS2 O75934 IFI35 Homo sapiens P80217-2
Validated Y2H
32296183
种属内
BCAS2 O75934 IFI35 Homo sapiens P80217-2
Y2H Array
32296183
种属内
BCAS2 O75934 SPMIP5 Homo sapiens Q8WW14-2
Y2H Prey Pooling
32296183
种属内
BCAS2 O75934 SPMIP5 Homo sapiens Q8WW14-2
Validated Y2H
32296183
种属内
BCAS2 O75934 SPMIP5 Homo sapiens Q8WW14-2
Y2H Array
32296183
种属内
BCAS2 O75934 FAM86C1P Homo sapiens Q9NVL1-2
Y2H Prey Pooling
32296183
种属内
BCAS2 O75934 FAM86C1P Homo sapiens Q9NVL1-2
Validated Y2H
32296183
种属内
BCAS2 O75934 FAM86C1P Homo sapiens Q9NVL1-2
Y2H Array
32296183
种属内
BCAS2 O75934 LMO4 Homo sapiens P61968
Validated Y2H
32296183
种属内
BCAS2 O75934 LMO4 Homo sapiens P61968
Y2H Prey Pooling
32296183
种属内
BCAS2 O75934 LMO4 Homo sapiens P61968
Y2H Array
32296183
种属内
BCAS2 O75934 MIIP Homo sapiens Q5JXC2
Validated Y2H
32296183
种属内
BCAS2 O75934 MIIP Homo sapiens Q5JXC2
Y2H Array
32296183
种属内
BCAS2 O75934 MIIP Homo sapiens Q5JXC2
Y2H Prey Pooling
32296183
种属内
BCAS2 O75934 PLAGL2 Homo sapiens Q9UPG8
Y2H Prey Pooling
32296183
种属内
BCAS2 O75934 PLAGL2 Homo sapiens Q9UPG8
Validated Y2H
32296183
种属内
BCAS2 O75934 PLAGL2 Homo sapiens Q9UPG8
Y2H Array
32296183
种属内
BCAS2 O75934 TXN2 Homo sapiens Q99757
Validated Y2H
32296183
种属内
BCAS2 O75934 KRT75 Homo sapiens O95678
Y2H Prey Pooling
32296183
种属内
BCAS2 O75934 KRT75 Homo sapiens O95678
Validated Y2H
32296183
种属内
BCAS2 O75934 KRT75 Homo sapiens O95678
Y2H Array
32296183
种属内
BCAS2 O75934 PAX5 Homo sapiens Q02548
Y2H Prey Pooling
32296183
种属内
BCAS2 O75934 PAX5 Homo sapiens Q02548
Validated Y2H
32296183
种属内
BCAS2 O75934 PAX5 Homo sapiens Q02548
Y2H Array
32296183
种属内
BCAS2 O75934 KRT27 Homo sapiens Q7Z3Y8
Y2H Prey Pooling
32296183
种属内
BCAS2 O75934 KRT27 Homo sapiens Q7Z3Y8
Validated Y2H
32296183
种属内
BCAS2 O75934 KRT27 Homo sapiens Q7Z3Y8
Y2H Array
32296183
种属内
BCAS2 O75934 EMILIN3 Homo sapiens Q9NT22
Y2H Prey Pooling
32296183
种属内
BCAS2 O75934 EMILIN3 Homo sapiens Q9NT22
Validated Y2H
32296183
种属内
BCAS2 O75934 EMILIN3 Homo sapiens Q9NT22
Y2H Array
32296183
种属内
BCAS2 O75934 SF3B4 Homo sapiens Q15427
Anti Tag CoIP
22365833
种属内
BCAS2 O75934 SF3B4 Homo sapiens Q15427
Y2H
22365833
种属内
BCAS2 O75934 PFDN5 Homo sapiens Q99471
Y2H Prey Pooling
32296183
种属内
BCAS2 O75934 PFDN5 Homo sapiens Q99471
Validated Y2H
32296183
种属内
BCAS2 O75934 PFDN5 Homo sapiens Q99471
Y2H Array
32296183
种属内
BCAS2 O75934 SMARCD1 Homo sapiens Q96GM5
Validated Y2H
32296183
种属内
BCAS2 O75934 CDC5L Homo sapiens Q99459
Anti Tag CoIP
33961781
种属内
BCAS2 O75934 CDC5L Homo sapiens Q99459
Y2H
22365833
种属内
BCAS2 O75934 CDC5L Homo sapiens Q99459
Crosslink
30021884
种属内
BCAS2 O75934 CDC5L Homo sapiens Q99459
Anti Tag CoIP
20176811
种属内
BCAS2 O75934 CDC5L Homo sapiens Q99459
Far-WB
20176811
种属内
BCAS2 O75934 CDC5L Homo sapiens Q99459
Pull Down
20176811
种属内
BCAS2 O75934 MED29 Homo sapiens Q9NX70
Validated Y2H
32296183
种属内
BCAS2 O75934 MED29 Homo sapiens Q9NX70
Y2H Array
32296183
种属内
BCAS2 O75934 MED29 Homo sapiens Q9NX70
Y2H Prey Pooling
32296183
种属内
BCAS2 O75934 PRPF19 Homo sapiens Q9UMS4
Anti Tag CoIP
20176811
种属内
BCAS2 O75934 PRPF19 Homo sapiens Q9UMS4
Pull Down
20176811
种属内
BCAS2 O75934 PRPF19 Homo sapiens Q9UMS4
Y2H
22365833
种属内
BCAS2 O75934 PRPF19 Homo sapiens Q9UMS4
Anti Tag CoIP
33961781
种属内
BCAS2 O75934 PRPF19 Homo sapiens Q9UMS4
Far-WB
20176811
种属内
BCAS2 O75934 OIP5 Homo sapiens O43482
Y2H Prey Pooling
32296183
种属内
BCAS2 O75934 OIP5 Homo sapiens O43482
Y2H Array
32296183
种属内
BCAS2 O75934 PRPF8 Homo sapiens Q6P2Q9
Anti Tag CoIP
33961781
种属内
BCAS2 O75934 PRPF8 Homo sapiens Q6P2Q9
Anti Tag CoIP
22365833
种属内
BCAS2 O75934 PRPF8 Homo sapiens Q6P2Q9
Y2H
22365833
种属内
BCAS2 O75934 MYOZ3 Homo sapiens Q8TDC0
Y2H Prey Pooling
32296183
种属内
BCAS2 O75934 MYOZ3 Homo sapiens Q8TDC0
Validated Y2H
32296183
种属内
BCAS2 O75934 MYOZ3 Homo sapiens Q8TDC0
Y2H Array
32296183
种属内
BCAS2 O75934 GOLGA2 Homo sapiens Q08379
Validated Y2H
32296183
种属内
BCAS2 O75934 GOLGA2 Homo sapiens Q08379
Y2H Array
25416956
种属内
BCAS2 O75934 GOLGA2 Homo sapiens Q08379
Y2H Array
32296183
种属内
BCAS2 O75934 GOLGA2 Homo sapiens Q08379
Y2H Prey Pooling
25416956
种属内
BCAS2 O75934 GOLGA2 Homo sapiens Q08379
Validated Y2H
27107012
种属内
BCAS2 O75934 GOLGA2 Homo sapiens Q08379
Y2H Prey Pooling
32296183
种属内
BCAS2 O75934 GOLGA2 Homo sapiens Q08379
BFG-2H
27107012
种属内
BCAS2 O75934 PCBD2 Homo sapiens Q9H0N5
Y2H Prey Pooling
32296183
种属内
BCAS2 O75934 PCBD2 Homo sapiens Q9H0N5
Validated Y2H
32296183
种属内
BCAS2 O75934 PCBD2 Homo sapiens Q9H0N5
Y2H Array
32296183
种属内
BCAS2 O75934 HSF2BP Homo sapiens O75031
Y2H Prey Pooling
32296183
种属内
BCAS2 O75934 HSF2BP Homo sapiens O75031
Y2H Array
32296183
种属内
BCAS2 O75934 USHBP1 Homo sapiens Q8N6Y0
Validated Y2H
32296183
种属内
BCAS2 O75934 HGS Homo sapiens O14964
Y2H Array
25416956
种属内
BCAS2 O75934 TCHP Homo sapiens Q9BT92
Validated Y2H
32296183
种属内
BCAS2 O75934 ACY1 Homo sapiens Q03154
Y2H Prey Pooling
32296183
种属内
BCAS2 O75934 ACY1 Homo sapiens Q03154
Validated Y2H
32296183
种属内
BCAS2 O75934 ACY1 Homo sapiens Q03154
Y2H Array
32296183
种属内
BCAS2 O75934 KRT20 Homo sapiens P35900
Validated Y2H
32296183
种属内
BCAS2 O75934 PLEKHF2 Homo sapiens Q9H8W4
Y2H Prey Pooling
32296183
种属内
BCAS2 O75934 PLEKHF2 Homo sapiens Q9H8W4
Validated Y2H
32296183
种属内
BCAS2 O75934 PLEKHF2 Homo sapiens Q9H8W4
Y2H Array
32296183
种属内
BCAS2 O75934 ENKD1 Homo sapiens Q9H0I2
Validated Y2H
32296183
种属内
BCAS2 O75934 GFAP Homo sapiens P14136
Y2H Array
32814053
种属内
BCAS2 O75934 GFAP Homo sapiens P14136
Validated Y2H
32814053
种属内
BCAS2 O75934 GFAP Homo sapiens P14136
Y2H Pooling
32814053
种属内
BCAS2 O75934 CCDC120 Homo sapiens Q96HB5
Validated Y2H
32296183
种属内
BCAS2 O75934 AIMP2 Homo sapiens Q13155
Validated Y2H
25416956
种属内
BCAS2 O75934 AIMP2 Homo sapiens Q13155
Validated Y2H
32296183
种属内
BCAS2 O75934 AIMP2 Homo sapiens Q13155
Y2H Prey Pooling
32296183
种属内
BCAS2 O75934 AIMP2 Homo sapiens Q13155
Y2H Array
32296183
种属内
BCAS2 O75934 AIMP2 Homo sapiens Q13155
Y2H Prey Pooling
25416956
种属内
BCAS2 O75934 IKZF3 Homo sapiens Q9UKT9
Y2H Array
31515488
种属内
BCAS2 O75934 SNRPC Homo sapiens P09234
Validated Y2H
32296183
种属内
BCAS2 O75934 LMO1 Homo sapiens P25800
Y2H Prey Pooling
32296183
种属内
BCAS2 O75934 LMO1 Homo sapiens P25800
Y2H Array
32296183
种属内
BCAS2 O75934 LMO1 Homo sapiens P25800
Validated Y2H
32296183
种属内
BCAS2 O75934 ECM1 Homo sapiens Q16610
Y2H Array
32296183
种属内
BCAS2 O75934 ECM1 Homo sapiens Q16610
Validated Y2H
32296183
种属内
BCAS2 O75934 ECM1 Homo sapiens Q16610
Y2H Prey Pooling
32296183
种属内
BCAS2 O75934 KRT31 Homo sapiens Q15323
Validated Y2H
32296183
种属内
BCAS2 O75934 KRT31 Homo sapiens Q15323
Y2H Array
32296183
种属内
BCAS2 O75934 KRT31 Homo sapiens Q15323
Y2H Prey Pooling
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

重组 BCAS2 蛋白

目录号 产品名 蛋白编号 纯度
HY-P7649 BCAS2 Protein, Human (His, T7) O75934 (A2-F225) ≥95%
HY-P700271 BCAS2 Protein, Human (N-GST) O75934 (A2-F225) ≥95%

关联疾病

疾病名称 别名
Breast Cancer

Breast Carcinoma

Male Breast Cancer

Breast Cancer, Familial

Malignant Neoplasm Of Breast

Breast Cancer, Susceptibility To

Breast Cancer, Early-Onset

Malignant Tumor Of Breast

Carcinoma Of Male Breast

Breast Cancer, Invasive Ductal

Breast Cancer, Protection Against

Breast Cancer, Somatic

Breast Cancer, Male

Breast Cancer, Lobular, Somatic

Breast Tumor

Mammary Cancer

Mammary Tumor

Malignant Neoplasm Of Male Breast

Mammary Carcinoma

Male Breast Carcinoma

Familial Cancer Of Breast

Invasive Ductal Breast Carcinoma

Breast Cancer Susceptibility

Breast Cancer, Male, Susceptibility To

Breast Cancer, Early-Onset, Susceptibility To

Malignant Tumor Of The Breast

Mammary Neoplasm

Primary Breast Cancer

Neoplasm Of Male Breast

Carcinoma Of Breast

Breast Cancer In Men

Familial Breast Cancer

Cancer Of Breast

BC

Breast Cancer Familial

Breast Cancer Familial Male

Breast Cancer, Familial Male

Breast Male Carcinoma

Breast Neoplasms

Breast Neoplasms, Male

Mammary Tumors

Mammary Carcinomas

Cancer, Breast

Cancer, Breast, Susceptibility

Invasive Breast Ductal Carcinoma

Breast Neoplasm

Susceptibility To Breast Cancer

Mammary Neoplasms

Animal Mammary Neoplasms

Primary Malignant Neoplasm Of Breast

Infiltrating Ductal Carcinoma Of Breast

Infiltrating Duct Carcinoma Of Unspecified Site

Infiltrating Ductular Carcinoma Of Unspecified Site

Invasive Breast Carcinoma Of No Special Type

Microinvasive Carcinoma Of Breast

Carcinoma With Apocrine Differentiation

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Bos taurus BCAS2 VGNC VGNC:106650
Canis familiaris BCAS2 VGNC VGNC:38399
Felis catus BCAS2 VGNC VGNC:69196
Mus musculus BCAS2 MGD MGI:1915433
Rattus norvegicus BCAS2 RGD RGD:1306485
Macaca mulatta BCAS2 VGNC VGNC:106322
Others BCAS2 NCBI