CEBPG - CCAAT enhancer binding protein gamma Gene

中文名称：CCAAT 增强子结合蛋白γ

种属: Homo sapiens

同用名: GPE1BP; IG/EBP-1

关于 CEBPG

功能概要

C/EBP 转录因子家族调节病毒和细胞 CCAAT/增强子元件介导的转录。 C/EBP 蛋白包含 bZIP 区域，其特征在于蛋白质 C 末端一半的两个基序：一个参与 DNA 结合的碱性区域和一个参与二聚化的亮氨酸拉链基序。 C/EBP 家族由几种相关的蛋白质组成，C/EBP α、C/EBP β、C/EBP 伽马和 C/EBP δ，它们形成同二聚体并相互形成异二聚体。 CCAAT/增强子结合蛋白 γ 可与 Fos 协同结合 PRE-I 增强子元件。已发现该基因编码相同蛋白质的两个转录变体。[RefSeq 提供，2011 年 11 月]

The C/EBP family of transcription factors regulates viral and cellular CCAAT/enhancer element-mediated transcription. C/EBP proteins contain the bZIP region, which is characterized by two motifs in the C-terminal half of the protein: a basic region involved in DNA binding and a leucine zipper motif involved in dimerization. The C/EBP family consist of several related proteins, C/EBP alpha, C/EBP beta, C/EBP gamma, and C/EBP delta, that form homodimers and that form heterodimers with each Other. CCAAT/enhancer binding protein gamma may cooperate with Fos to bind PRE-I enhancer elements. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Nov 2011]