1. Gene
  2. DDIT3 - DNA damage inducible transcript 3 Gene

DDIT3 - DNA damage inducible transcript 3 Gene

中文名称:DNA 损伤诱导转录物 3

种属: Homo sapiens

同用名: CHOP; CEBPZ; CHOP10; CHOP-10; GADD153; AltDDIT3; C/EBPzeta

基因 ID: 1649 | 基因类型: protein coding

关于 DDIT3

Cytogenetic location: 12q13.3 Genomic coordinates (GRCh38): 12:57,516,588-57,521,698 (from NCBI)

This gene has 6 transcripts (splice variants), 193 orthologues and is associated with 51 phenotypes. Broad expression in thyroid (RPKM 74.2), bone marrow (RPKM 47.3) and 24 other tissues.

功能概要

该基因编码 CCAAT/增强子结合蛋白 (C/EBP) 转录因子家族的成员。该蛋白质通过与其他 C/EBP 成员 (如 C/EBP 和 LAP (肝激活蛋白) ) 形成异二聚体并阻止其 DNA 结合活性,从而发挥显性失活抑制剂的作用。该蛋白质与脂肪生成和红细胞生成有关,被内质网应激激活,并促进细胞凋亡。通过易位诱导该基因与 16 号染色体上的 FUS 或 22 号染色体上的 EWSR1 融合,在粘液样脂肪肉瘤或尤文肉瘤中产生嵌合蛋白。已经鉴定出编码两种不同长度的亚型的多个选择性剪接的转录本变体。[RefSeq 提供,2010 年 8 月]

This gene encodes a member of the CCAAT/enhancer-binding protein (C/EBP) family of transcription factors. The protein functions as a dominant-negative inhibitor by forming heterodimers with other C/EBP members, such as C/EBP and LAP (liver activator protein), and preventing their DNA binding activity. The protein is implicated in adipogenesis and erythropoiesis, is activated by endoplasmic reticulum stress, and promotes Apoptosis. Fusion of this gene and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in myxoid liposarcomas or Ewing sarcoma. Multiple alternatively spliced transcript variants encoding two isoforms with different length have been identified. [provided by RefSeq, Aug 2010]

DDIT3 基因产物(8)

mRNA Protein Name
NM_001195053.1 NP_001181982.1 DNA damage-inducible transcript 3 protein isoform 1
NM_001195054.1 NP_001181983.1 DNA damage-inducible transcript 3 protein isoform 1
NM_001195055.1 NP_001181984.1 DNA damage-inducible transcript 3 protein isoform 1
NM_001195056.1 NP_001181985.1 DNA damage-inducible transcript 3 protein isoform 1
NM_001195057.1 NP_001181986.1 DNA damage-inducible transcript 3 protein isoform 2
NM_001413641.1 NP_001400570.1 DNA damage-inducible transcript 3 protein isoform 2
NM_001413642.1 NP_001400571.1 DNA damage-inducible transcript 3 protein isoform 2
NM_004083.6 NP_004074.2 DNA damage-inducible transcript 3 protein isoform 2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables DNA binding IDA
IDA: 通过直接分析推断
14667815 GOA
enables DNA-binding transcription activator activity, RNA polymerase II-specific IDA
IDA: 通过直接分析推断
22065586 GOA
enables DNA-binding transcription factor activity IDA
IDA: 通过直接分析推断
30639358 GOA
enables DNA-binding transcription factor activity IGI
IGI: 通过遗传相互作用推断
24939851 GOA
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IDA
IDA: 通过直接分析推断
22065586 GOA
enables RNA polymerase II-specific DNA-binding transcription factor binding IPI
IPI: 通过物理相互作用推断
16434966 GOA
enables cAMP response element binding protein binding IPI
IPI: 通过物理相互作用推断
11478948 GOA
enables identical protein binding IPI
IPI: 通过物理相互作用推断
20562859 GOA
enables leucine zipper domain binding IDA
IDA: 通过直接分析推断
8622660 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
15775988 GOA
enables protein heterodimerization activity IPI
IPI: 通过物理相互作用推断
8622660 GOA
enables protein homodimerization activity IDA
IDA: 通过直接分析推断
18534616 GOA
enables transcription cis-regulatory region binding IDA
IDA: 通过直接分析推断
24939851 GOA
enables transcription corepressor activity IDA
IDA: 通过直接分析推断
24038088 GOA
enables transcription corepressor activity IGI
IGI: 通过遗传相互作用推断
11478948 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in HRI-mediated signaling IDA
IDA: 通过直接分析推断
32132706 GOA
acts upstream of or within cell redox homeostasis IDA
IDA: 通过直接分析推断
14667815 GOA
involved in integrated stress response signaling IDA
IDA: 通过直接分析推断
30639358 GOA
involved in intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress IDA
IDA: 通过直接分析推断
18940792 GOA
involved in intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress IMP
IMP: 通过突变表型推断
15322075 GOA
involved in negative regulation of DNA-templated transcription IDA
IDA: 通过直接分析推断
18940792 GOA
involved in negative regulation of determination of dorsal identity IDA
IDA: 通过直接分析推断
16434966 GOA
acts upstream of negative regulation of interleukin-17 production IMP
IMP: 通过突变表型推断
24038088 GOA
acts upstream of negative regulation of interleukin-4 production IMP
IMP: 通过突变表型推断
24038088 GOA
involved in negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction IMP
IMP: 通过突变表型推断
22761832 GOA
acts upstream of or within negative regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
24038088 GOA
involved in negative regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
16434966 GOA
involved in negative regulation of transcription by RNA polymerase II IGI
IGI: 通过遗传相互作用推断
11478948 GOA
acts upstream of negative regulation of type II interferon production IMP
IMP: 通过突变表型推断
24038088 GOA
involved in positive regulation of DNA-binding transcription factor activity IMP
IMP: 通过突变表型推断
18534616 GOA
involved in positive regulation of DNA-templated transcription IDA
IDA: 通过直接分析推断
15322075 GOA
involved in positive regulation of interleukin-8 production IMP
IMP: 通过突变表型推断
20829347 GOA
involved in positive regulation of intrinsic apoptotic signaling pathway IMP
IMP: 通过突变表型推断
27031958 GOA
involved in positive regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
15322075 GOA
involved in positive regulation of transcription by RNA polymerase II IGI
IGI: 通过遗传相互作用推断
15775988 GOA
involved in positive regulation of transcription by RNA polymerase II IMP
IMP: 通过突变表型推断
22065586 GOA
involved in proteasome-mediated ubiquitin-dependent protein catabolic process IDA
IDA: 通过直接分析推断
17872950 GOA
involved in regulation of DNA-templated transcription IMP
IMP: 通过突变表型推断
17872950 GOA
acts upstream of or within regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
14667815 GOA
involved in regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
8622660 GOA
involved in response to endoplasmic reticulum stress IDA
IDA: 通过直接分析推断
18940792 GOA
involved in response to endoplasmic reticulum stress IGI
IGI: 通过遗传相互作用推断
15775988 GOA
involved in response to unfolded protein IDA
IDA: 通过直接分析推断
18940792 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of CHOP-ATF3 complex IDA
IDA: 通过直接分析推断
8622660 GOA
part of CHOP-ATF4 complex IDA
IDA: 通过直接分析推断
11478948 GOA
part of CHOP-ATF4 complex IPI
IPI: 通过物理相互作用推断
18940792 GOA
part of CHOP-C/EBP complex IPI
IPI: 通过物理相互作用推断
20102225 GOA
part of RNA polymerase II transcription regulator complex IPI
IPI: 通过物理相互作用推断
20102225 GOA
located in cytoplasm IDA
IDA: 通过直接分析推断
29083303 GOA
located in nucleus IDA
IDA: 通过直接分析推断
11478948 GOA
part of protein-DNA complex IDA
IDA: 通过直接分析推断
15322075 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

DDIT3 蛋白结构

bZIP_2

bZIP_2: Basic region leucine zipper (102 - 151)

  • 0
  • 100
  • 169 a.a.
蛋白主名 其他名称

DNA damage-inducible transcript 3 protein

C/EBP zeta

DDIT3 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra DDIT3 P35638 BATF3 Homo sapiens Q9NR55
Y2H Array
20211142
Intra DDIT3 P35638 BATF3 Homo sapiens Q9NR55
FRET
23661758
Intra DDIT3 P35638 BATF3 Homo sapiens Q9NR55
Validated Y2H
32296183
Intra DDIT3 P35638 G3BP1 Homo sapiens Q13283
FPS
34799561
Intra DDIT3 P35638 JPH3 Homo sapiens Q8WXH2
Validated Y2H
32814053
Intra DDIT3 P35638 JPH3 Homo sapiens Q8WXH2
Y2H Array
32814053
Intra DDIT3 P35638 JPH3 Homo sapiens Q8WXH2
Y2H Pooling
32814053
Intra DDIT3 P35638 ATF2 Homo sapiens P15336
FRET
23661758
Intra DDIT3 P35638 CEBPA Homo sapiens P49715
Anti Tag CoIP
33961781
Intra DDIT3 P35638 CEBPA Homo sapiens P49715
FRET
23661758
Intra DDIT3 P35638 CEBPA Homo sapiens P49715
Peptide Array
20102225
Intra DDIT3 P35638 EMSY Homo sapiens Q7Z589-5
Validated Y2H
32296183
Intra DDIT3 P35638 TXNDC2 Homo sapiens Q86VQ3
Validated Y2H
32296183
Intra DDIT3 P35638 JDP2 Homo sapiens Q8WYK2
Validated Y2H
32296183
Intra DDIT3 P35638 BACH1 Homo sapiens O14867
Peptide Array
20102225
Intra DDIT3 P35638 BACH1 Homo sapiens O14867
FRET
23661758
Intra DDIT3 P35638 VPS37C Homo sapiens A5D8V6
Y2H Prey Pooling
32296183
Intra DDIT3 P35638 HLF Homo sapiens Q16534
FRET
23661758
Intra DDIT3 P35638 TXN2 Homo sapiens Q99757
Validated Y2H
32296183
Intra DDIT3 P35638 TEDC1 Homo sapiens Q86SX3
Anti Tag CoIP
33961781
Intra DDIT3 P35638 TEDC1 Homo sapiens Q86SX3
Anti Tag CoIP
20562859
Intra DDIT3 P35638 TEDC1 Homo sapiens Q86SX3
Y2H
18330356
Intra DDIT3 P35638 FOSL2 Homo sapiens P15408
Validated Y2H
27107012
Intra DDIT3 P35638 DBP Homo sapiens Q10586
Y2H Array
21988832
Intra DDIT3 P35638 DBP Homo sapiens Q10586
FRET
23661758
Intra DDIT3 P35638 NFIL3 Homo sapiens Q16649
FRET
23661758
Intra DDIT3 P35638 NFIL3 Homo sapiens Q16649
Peptide Array
20102225
Intra DDIT3 P35638 ATF4 Homo sapiens P18848
FRET
23661758
Intra DDIT3 P35638 ATF4 Homo sapiens P18848
Y2H
18330356
Intra DDIT3 P35638 CREB3 Homo sapiens O43889
FRET
23661758
Intra DDIT3 P35638 CRACR2A Homo sapiens Q9BSW2
Validated Y2H
32296183
Intra DDIT3 P35638 LNX1 Homo sapiens Q8TBB1
Validated Y2H
32296183
Intra DDIT3 P35638 CEBPG Homo sapiens P53567
Peptide Array
20102225
Intra DDIT3 P35638 CEBPG Homo sapiens P53567
FRET
23661758
Intra DDIT3 P35638 CEBPG Homo sapiens P53567
Anti Tag CoIP
33961781
Intra DDIT3 P35638 HSD17B14 Homo sapiens Q9BPX1
Validated Y2H
27107012
Intra DDIT3 P35638 HSD17B14 Homo sapiens Q9BPX1
Validated Y2H
32296183
Intra DDIT3 P35638 HSD17B14 Homo sapiens Q9BPX1
Y2H Pooling
16189514
Intra DDIT3 P35638 BATF2 Homo sapiens Q8N1L9
FRET
23661758
Intra DDIT3 P35638 GFAP Homo sapiens P14136
Y2H Array
32814053
Intra DDIT3 P35638 GFAP Homo sapiens P14136
Y2H Pooling
32814053
Intra DDIT3 P35638 GFAP Homo sapiens P14136
Validated Y2H
32814053
Intra DDIT3 P35638 BATF Homo sapiens Q16520
Y2H
18330356
Intra DDIT3 P35638 BATF Homo sapiens Q16520
Y2H Pooling
16189514
Intra DDIT3 P35638 BATF Homo sapiens Q16520
FRET
23661758
Intra DDIT3 P35638 ATF7 Homo sapiens P17544
Anti Tag CoIP
33961781
Intra DDIT3 P35638 CEBPD Homo sapiens P49716
Peptide Array
20102225
Intra DDIT3 P35638 FOS Homo sapiens P01100
SLC
31467278
Intra DDIT3 P35638 FOS Homo sapiens P01100
Lumier
32814053
Intra DDIT3 P35638 FOS Homo sapiens P01100
Lumier
37398436
Intra DDIT3 P35638 FOS Homo sapiens P01100
Peptide Array
20102225
Intra DDIT3 P35638 FOS Homo sapiens P01100
BRET
29997244
Intra DDIT3 P35638 MCMBP Homo sapiens Q9BTE3-2
Validated Y2H
32296183
Intra DDIT3 P35638 CEBPB Homo sapiens P17676
Anti Tag CoIP
33961781
Intra DDIT3 P35638 CEBPB Homo sapiens P17676
Peptide Array
20102225
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Myxoid Liposarcoma

Myxoid/Round Cell Liposarcoma

Liposarcoma, Myxoid

Mrcls

Myxoliposarcoma

MXLIPO

Liposarcoma Myxoid

Liposarcoma

Liposarcoma

Lipomatous Cancer

Fatty Liver Disease

Alcoholic Fatty Liver

Fatty Liver

Fatty Liver, Alcoholic

Fatty Change Of Liver

Hepatic Lipidosis

Steatosis Of Liver

Fatty Liver Alcoholic

Steatohepatitis

Etoh Fatty Liver

Etoh Fatty Liver Metamorphosis

Fatty Etoh Liver Necrosis

Sarcoma

Connective And Soft Tissue Neoplasm

Tumor Of Soft Tissue And Skeleton

Sarcomas

Sarcoma - Category

Malignant Fibrous Histiocytoma

Undifferentiated Pleomorphic Sarcoma

Ups

Histiocytoma, Malignant Fibrous

Fibroxanthosarcoma

Mfh

Malignant Fibrohistiocytic Tumors

Histiocytoma, Fibrous, Malignant

Ewing Sarcoma

Neuroepithelioma

Ewing'S Tumor

Primitive Neuroectodermal Tumor

Ewings Sarcoma

Ewing'S Sarcoma

Peripheral Neuroepithelioma

ES

Ewings Sarcoma-Primitive Neuroectodermal Tumor

Localized Peripheral Primitive Neuroectodermal Tumor

Peripheral Primitive Neuroectodermal Tumor

Ewing Tumor

Sarcoma, Ewing'S

Ewing Family Of Tumors

Extraosseous Ewing Tumor

Askin Tumor

Ewing'S Family Localized Tumor

Ewing'S Sarcoma/Peripheral Primitive Neuroectodermal Tumor

Localized Ewing Sarcoma

Localized Ewing'S Sarcoma

Localized Ewing'S Sarcoma/Peripheral Primitive Neuroectodermal Tumor

Localized Ewing'S Tumor

Pnet Of Thoracopulmonary Region

Tumor Of The Ewing Family

Skeletal Ewing Sarcoma

Osseous Ewing Sarcoma

Ppnet

Peripheral Pnet

Extraskeletal Ewing Sarcoma

Eoe

Extraosseous Ewing Sarcoma

Extraskeletal Ewing Tumor

Esft

Ewing Sarcoma Family Of Tumors

Pne

Pnet

Pnet Of The Chest Wall

Sarcoma, Ewing

Neuroectodermal Tumors, Primitive, Peripheral

Neuroectodermal Tumor, Primitive

Disorder Of Eye

Askin'S Tumor

Extraosseous Ewings Sarcoma-Primitive Neuroepithelial Tumor

Neuroepithelioma, Peripheral

Well-Differentiated Liposarcoma

Atypical Lipomatous Tumor

Atypical Lipoma

Alt

Wdls

Liposarcoma, Well Differentiated

Pleomorphic Lipoma

Lipomatosis, Multiple

Lipoma

Familial Multiple Lipomatosis

Lipomatosis, Familial Multiple

Benign Lipomatous Tumor

Lipomatous Neoplasm

Multiple Lipomatosis

Fml

Lipo

Benign Tumor Of Adipose Tissue

Lipomatous Tumor

Tumor Of Adipose Tissue

Neoplasms, Adipose Tissue

Lipomas

Pleomorphic Liposarcoma

Pls

Liposarcoma Pleomorphic

Liposarcoma, Pleomorphic

Cellular Myxoid Liposarcoma

Round Cell Liposarcoma

Liver Disease

Liver Failure

Liver Diseases

Abnormality Of The Liver

Liver Dysfunction

Disorder Of Liver

Hepatic Disorder

Hepatic Disease

Disease Of Bilirubin Metabolism

Disorder Of Bilirubin Metabolism

Liver Decompensation

Liver Function Failure

Hepatic Failure Nos

Liver Failure Nos

End Stage Liver Disease

Decompensated Liver Failure

Decompensation Of Liver Function

Hepatic Decompensation

Hepatic Insufficiency

Liver Cell Necrosis With Hepatic Failure

Liver Insufficiency

Decompensated Liver Disease

End Stage Liver Failure

Liver Necrosis With Hepatic Failure

Childhood Liposarcoma

Pediatric Liposarcoma

Myxoid Liposarcoma Of The Ovary

Myxoid Liposarcoma Of Ovary

Liposarcoma Of The Ovary

Liposarcoma Of Ovary

Open-Angle Glaucoma

Glaucoma Simplex

Pigmentary Glaucoma

Wide-Angle Glaucoma

Glaucoma, Open-Angle

Open Angle Glaucoma

Glaucoma Open-Angle

Chronic Simple Glaucoma

Coag - [Chronic Open-Angle Glaucoma]

Csg - [Chronic Simple Glaucoma]

Poag - [Primary Open-Angle Glaucoma]

Oag - [Open-Angle Glaucoma]

Chronic Glaucoma

Chronic Open Angle Glaucoma

Simple Glaucoma

Chronic Noncongestive Glaucoma

Ltg - [Low Tension Glaucoma]

Noncongestive Glaucoma

Nonobstructive Glaucoma

Normal Pressure Glaucoma

Primary Low Tension Glaucoma

Low-Tension Glaucoma

Residual Stage Low Tension Glaucoma

Open Cleft Glaucoma

Pancreas Sarcoma

Sarcoma Of Pancreas

Spindle Cell Lipoma
Pleomorphic Lipoma

Lipoma

Lipoma Pleomorphic

Lipomatosis, Multiple

Myxofibrosarcoma

Fibromyxosarcoma

Fibromyxoid Sarcoma

Myxoid Malignant Fibrous Histiocytoma

Dermatofibrosarcoma Protuberans, Myxoid

Dedifferentiated Liposarcoma

Ddls

Liposarcoma Dedifferentiated

Liposarcoma, Dedifferentiated

Glioblastoma

Glioblastoma Multiforme

Gbm

Adult Glioblastoma Multiforme

Grade Iv Adult Astrocytic Tumor

Primary Glioblastoma Multiforme

Spongioblastoma Multiforme

Adult Glioblastoma

Primary Glioblastoma

Epiphyseal Dysplasia, Multiple, With Early-Onset Diabetes Mellitus

Wolcott-Rallison Syndrome

Med-Iddm Syndrome

Iddm-Med Syndrome

Wolcott Rallison Syndrome

WRS

Epiphyseal Dysplasia Multiple With Early-Onset Diabetes Mellitus

Early-Onset Diabetes Mellitus With Multiple Epiphyseal Dysplasia

Multiple Epiphyseal Dysplasia With Early-Onset Diabetes Mellitus

Chondrosarcoma, Extraskeletal Myxoid

Extraskeletal Myxoid Chondrosarcoma

Emc

Myxoid Extraosseous Chondrosarcoma

Colorectal Cancer

Colon Cancer

Colorectal Carcinoma

Colon Carcinoma

Colorectal Cancer, Susceptibility To

Carcinoma Of Colon

CRC

Colorectal Cancer With Chromosomal Instability, Somatic

Colon Cancer, Somatic

Colon Cancer, Susceptibility To

Colonic Neoplasms

Colorectal Neoplasms

Colorectal Cancer, Somatic

Colon Cancer, Advanced, Somatic

Colonic Carcinoma

Colorectal Carcinomas

Colon Cancers

Colorectal Cancers

Cancer, Colorectal, Somatic

Cancer, Colon

Cancer, Colorectal, Susceptibility To

Colorectal Neoplasm

Colonic Neoplasm

Malignant Tumor Of Colon

Hepatocellular Carcinoma

Liver Cancer

Primary Liver Cancer

HCC

Hepatoma

Malignant Neoplasm Of Liver

Liver Neoplasms

Cancer, Hepatocellular

Liver Cell Carcinoma

Lcc

Hepatoblastoma, Somatic

Hepatic Cancer

Primary Malignant Neoplasm Of Liver

Rare Tumor Of Liver And Intrahepatic Biliary Tract

Hepatocellular Carcinoma, Somatic

Hepatocellular Carcinoma, Childhood Type, Somatic

Hepatocellular Cancer, Somatic

Ca Liver - Primary

Hepatic Neoplasm

Malignant Hepato-Biliary Neoplasm

Malignant Neoplasm Of Liver, Not Specified As Primary Or Secondary

Malignant Neoplasm Of Liver, Primary

Malignant Tumor Of Liver

Neoplasm Of Liver

Non-Resectable Primary Hepatic Malignant Neoplasm

Resectable Malignant Neoplasm Of Liver

Resectable Malignant Neoplasm Of The Liver

Primary Liver Carcinoma

Primary Malignant Liver Neoplasm

Primary Cancer Of Liver

Primary Tumor Of The Liver

Rare Tumor Of Liver And Ibt

Hepatocellular Cancer

Neoplasm Of The Liver

Carcinoma, Hepatocellular

Hepatomas

Liver Neoplasm

Liver Carcinoma

Liver And Intrahepatic Biliary Tract Carcinoma

Malignant Hepatobiliary Neoplasm

Adult Primary Hepatocellular Carcinoma

Hepatoblastoma

Carcinoma Of Liver

Malignant Liver Tumour

Malignant Hepatic Tumour

Myeloma, Multiple

Multiple Myeloma

Plasma Cell Myeloma

Kahler Disease

Myelomatosis

Medullary Plasmacytoma

Multiple Myeloma, Resistance To

Myeloma

Plasma Cell Dyscrasia

Kahler'S Disease

Multiple Myeloma, Susceptibility To

Myeloma - Multiple

Kahler-Bozzolo Disease

Plasma Cell Myelomas

MM

Plasma Cell Neoplasm

Primary Systemic Amyloidosis

Primary Amyloidosis

Immunoglobulin Deposition Disease

Plasmacytic Myeloma

Multiple Myelomata

Multiple Myeloma Nos

Multiple Myeloma Without Mention Of Remission

Monostotic Plasma Cell Myeloma

Mm - [Multiple Myeloma]

Cystic Fibrosis

Mucoviscidosis

CF

Pseudomonas Aeruginosa, Susceptibility To Chronic Infection By, In Cystic Fibrosis

Pseudomonas Aeruginosa Chronic Infection By, In Cystic Fibrosis

Cystic Fibrosis Lung Disease, Modifier Of

Cystic Fibrosis Of Pancreas

Fibrocystic Disease Of Pancreas

Cf - [Cystic Fibrosis]

Cystic Fibrosis Nos

Fibrocystic Disease

Fibrocystic Disease Of The Pancreas

Mucoviscidosis Of Pancreas

Nonproliferative Fibrocystic Disease

Pancreatic Cystic Fibrosis

Prostate Cancer

Prostate Carcinoma

Prostate Cancer, Familial

Prostate Neoplasm

Prostate Cancer, Somatic

Prostate Cancer, Susceptibility To

Prostatic Cancer

Prostatic Neoplasms

Hereditary Prostate Cancer

Prostatic Neoplasm

Cancer Of Prostate

Carcinoma Of Prostate

Familial Prostate Cancer

Familial Prostate Carcinoma

Malignant Tumor Of Prostate

Malignant Neoplasm Of Prostate

Prostate Cancer, Familial, Susceptibility To

Malignant Tumor Of The Prostate

Ngp - New Growth Of Prostate

Tumor Of The Prostate

Prostate Cancer, Hereditary

Cancer Of The Prostate

Malignant Neoplasm Of The Prostate

Prostatic Carcinoma

PC

Prca

Cancer, Prostate

Malignant Prostatic Tumour

Malignant Tumour Of Prostate

Primary Prostate Cancer

Primary Malignant Neoplasm Of Prostate

Prostate Gland Cancer

Diabetes Mellitus

Diabetes

Parkinson Disease, Late-Onset

Parkinson Disease

Parkinson'S Disease

PD

PARK

Parkinson Disease, Susceptibility To

Late Onset Parkinson'S Disease

Late Onset Parkinson Disease

Paralysis Agitans

Primary Parkinsonism

Idiopathic Parkinson Disease

Parkinson'S

Parkinson Disease, Late-Onset, Susceptibility To

Parkinson Disease, Age Of Onset, Modifier

Lewy Body Parkinson Disease

Idiopathic Parkinson'S Disease

Pd - [Parkinson Disease]

Parkinson Disease Nos

Parkinson, Nos

Primary Parkinson Disease

Amyotrophic Lateral Sclerosis 1

Amyotrophic Lateral Sclerosis

ALS

Lou Gehrig Disease

Amyotrophic Lateral Sclerosis Type 1

Charcot Disease

ALS1

Amyotrophic Lateral Sclerosis, Susceptibility To

Fals

Lou Gehrig'S Disease

Mnd

Motor Neuron Disease

Familial Amyotrophic Lateral Sclerosis

Amyotrophic Lateral Sclerosis 1, Familial

Amyotrophic Lateral Sclerosis 1, Autosomal Dominant

Motor Neuron Disease, Bulbar

Motor Neurone Disease

Amyotrophic Lateral Sclerosis With Dementia

Dementia With Amyotrophic Lateral Sclerosis

Motor Neuron Disease, Amyotrophic Lateral Sclerosis

Sclerosis, Lateral, Amyotrophic

Sclerosis, Lateral, Amyotrophic, Type 1

Amyotrophic Sclerosis

Als - [Amyotrophic Lateral Sclerosis]

Wasting Palsy

Amyotrophic Paralysis

Amyotrophy Lateral Sclerosis

Wasting Paralysis

Spinal Progressive Amyotrophy

Progressive Atrophic Paralysis

Nervous System Disease

Abnormality Of The Nervous System

Nervous System Diseases

Nervous System Disorder

Retinitis Pigmentosa

RP

Rod-Cone Dystrophy

Autosomal Recessive Retinitis Pigmentosa

Non-Syndromic Retinitis Pigmentosa

Pericentral Pigmentary Retinopathy

Pigmentary Retinopathy

Tapetoretinal Degeneration

Rcd

Retinitis Pigmentosa Autosomal Recessive

ARRP

Retinitis Pigmentosa, Autosomal Recessive

Retinitis Pigmentosa 1

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Mus musculus DDIT3 MGD MGI:109247
Rattus norvegicus DDIT3 RGD RGD:62391
Canis familiaris DDIT3 VGNC VGNC:39836
Felis catus DDIT3 VGNC VGNC:61389
Macaca mulatta DDIT3 VGNC VGNC:71756
Bos taurus DDIT3 VGNC VGNC:27947