2. Gene
  3. MTURN - maturin, neural progenitor differentiation regulator homolog Gene

MTURN - maturin, neural progenitor differentiation regulator homolog Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：成熟蛋白，神经祖细胞分化调节因子同系物

种属: Homo sapiens

同用名: Ells1; C7orf41

基因 ID: 222166 | 基因类型: protein coding

关于 MTURN

This gene has 4 transcripts (splice variants) and 188 orthologues. Biased expression in brain (RPKM 152.3), fat (RPKM 61.0) and 8 other tissues.

功能概要

参与 NF-kappaB 转录因子活性的负调控； MAPK 级联的正调控；和巨核细胞分化的正调控。位于细胞质中。 [由基因组资源联盟提供，2022 年 4 月]

Involved in negative regulation of NF-kappaB transcription factor activity; positive regulation of MAPK cascade; and positive regulation of megakaryocyte differentiation. Located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]

MTURN 基因产物(1)

mRNA Protein Name
NM_152793.3 NP_690006.2 maturin
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
32296183 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in negative regulation of NF-kappaB transcription factor activity IMP
IMP: 通过突变表型推断
24681962 GOA
involved in positive regulation of ERK1 and ERK2 cascade IMP
IMP: 通过突变表型推断
24681962 GOA
involved in positive regulation of JNK cascade IMP
IMP: 通过突变表型推断
24681962 GOA
involved in positive regulation of megakaryocyte differentiation IMP
IMP: 通过突变表型推断
24681962 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasm IDA
IDA: 通过直接分析推断
24681962 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

MTURN 蛋白结构

DUF4581

DUF4581: Domain of unknown function (DUF4581) (4 - 131)

  • 0
  • 100
  • 131 a.a.
蛋白主名 其他名称

maturin

UPF0452 protein C7orf41

MTURN 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra MTURN Q8N3F0 SSX1 Homo sapiens Q16384
Y2H Prey Pooling
32296183
Intra MTURN Q8N3F0 SSX1 Homo sapiens Q16384
Y2H Array
32296183
Intra MTURN Q8N3F0 REL Homo sapiens Q04864-2
Y2H Prey Pooling
32296183
Intra MTURN Q8N3F0 REL Homo sapiens Q04864-2
Y2H Array
32296183
Intra MTURN Q8N3F0 TRIM39 Homo sapiens Q9HCM9-2
Y2H Prey Pooling
32296183
Intra MTURN Q8N3F0 TRIM39 Homo sapiens Q9HCM9-2
Validated Y2H
32296183
Intra MTURN Q8N3F0 TRIM39 Homo sapiens Q9HCM9-2
Y2H Array
32296183
Intra MTURN Q8N3F0 TMEM239 Homo sapiens Q8WW34-2
Y2H Array
32296183
Intra MTURN Q8N3F0 TMEM239 Homo sapiens Q8WW34-2
Y2H Prey Pooling
32296183
Intra MTURN Q8N3F0 TMEM239 Homo sapiens Q8WW34-2
Validated Y2H
32296183
Intra MTURN Q8N3F0 TP53BP2 Homo sapiens Q05BL1
Y2H Array
32296183
Intra MTURN Q8N3F0 TP53BP2 Homo sapiens Q05BL1
Y2H Prey Pooling
32296183
Intra MTURN Q8N3F0 TNFRSF19 Homo sapiens Q9NS68-2
Y2H Prey Pooling
32296183
Intra MTURN Q8N3F0 TNFRSF19 Homo sapiens Q9NS68-2
Validated Y2H
32296183
Intra MTURN Q8N3F0 TNFRSF19 Homo sapiens Q9NS68-2
Y2H Array
32296183
Intra MTURN Q8N3F0 TRIM5 Homo sapiens Q9C035-3
Y2H Prey Pooling
32296183
Intra MTURN Q8N3F0 TRIM5 Homo sapiens Q9C035-3
Y2H Array
32296183
Intra MTURN Q8N3F0 TRIM5 Homo sapiens Q9C035-3
Validated Y2H
32296183
Intra MTURN Q8N3F0 RNF41 Homo sapiens Q9H4P4
Y2H Prey Pooling
32296183
Intra MTURN Q8N3F0 RNF41 Homo sapiens Q9H4P4
Validated Y2H
32296183
Intra MTURN Q8N3F0 RNF41 Homo sapiens Q9H4P4
Y2H Array
32296183
Intra MTURN Q8N3F0 TRIM38 Homo sapiens O00635
Y2H Array
32296183
Intra MTURN Q8N3F0 TRIM38 Homo sapiens O00635
Y2H Prey Pooling
32296183
Intra MTURN Q8N3F0 ARRDC1 Homo sapiens Q8N5I2
Y2H Prey Pooling
32296183
Intra MTURN Q8N3F0 ARRDC1 Homo sapiens Q8N5I2
Validated Y2H
32296183
Intra MTURN Q8N3F0 ARRDC1 Homo sapiens Q8N5I2
Y2H Array
32296183
Intra MTURN Q8N3F0 TRIM8 Homo sapiens Q9BZR9
Y2H Prey Pooling
32296183
Intra MTURN Q8N3F0 TRIM8 Homo sapiens Q9BZR9
Validated Y2H
32296183
Intra MTURN Q8N3F0 TRIM8 Homo sapiens Q9BZR9
Y2H Array
32296183
Intra MTURN Q8N3F0 SUSD6 Homo sapiens Q92537
Y2H Array
32296183
Intra MTURN Q8N3F0 SUSD6 Homo sapiens Q92537
Y2H Prey Pooling
32296183
Intra MTURN Q8N3F0 SUSD6 Homo sapiens Q92537
Validated Y2H
32296183
Intra MTURN Q8N3F0 AP2M1 Homo sapiens Q96CW1
Validated Y2H
32296183
Intra MTURN Q8N3F0 AP2M1 Homo sapiens Q96CW1
Y2H Prey Pooling
32296183
Intra MTURN Q8N3F0 AP2M1 Homo sapiens Q96CW1
Y2H Array
32296183
Intra MTURN Q8N3F0 UBC Homo sapiens P0CG48
Y2H Array
32296183
Intra MTURN Q8N3F0 UBC Homo sapiens P0CG48
Y2H Prey Pooling
32296183
Intra MTURN Q8N3F0 UBA52 Homo sapiens P62987
Y2H Array
32296183
Intra MTURN Q8N3F0 UBA52 Homo sapiens P62987
Y2H Prey Pooling
32296183
Intra MTURN Q8N3F0 RPS27A Homo sapiens P62979
Y2H Prey Pooling
32296183
Intra MTURN Q8N3F0 RPS27A Homo sapiens P62979
Y2H Array
32296183
Intra MTURN Q8N3F0 TRAF6 Homo sapiens Q9Y4K3
Y2H Array
32296183
Intra MTURN Q8N3F0 TRAF6 Homo sapiens Q9Y4K3
Y2H Prey Pooling
32296183
Intra MTURN Q8N3F0 TRAF6 Homo sapiens Q9Y4K3
Validated Y2H
32296183
Intra MTURN Q8N3F0 MKRN1 Homo sapiens Q9UHC7
Y2H Prey Pooling
32296183
Intra MTURN Q8N3F0 MKRN1 Homo sapiens Q9UHC7
Validated Y2H
32296183
Intra MTURN Q8N3F0 MKRN1 Homo sapiens Q9UHC7
Y2H Array
32296183
Intra MTURN Q8N3F0 PLEKHB2 Homo sapiens Q96CS7
Y2H Array
32296183
Intra MTURN Q8N3F0 PLEKHB2 Homo sapiens Q96CS7
Validated Y2H
32296183
Intra MTURN Q8N3F0 PLEKHB2 Homo sapiens Q96CS7
Y2H Prey Pooling
32296183
Intra MTURN Q8N3F0 UBB Homo sapiens P0CG47
Y2H Prey Pooling
32296183
Intra MTURN Q8N3F0 UBB Homo sapiens P0CG47
Y2H Array
32296183
Intra MTURN Q8N3F0 RNF216 Homo sapiens Q9NWF9
Y2H Prey Pooling
32296183
Intra MTURN Q8N3F0 RNF216 Homo sapiens Q9NWF9
Y2H Array
32296183
Intra MTURN Q8N3F0 DAZAP2 Homo sapiens Q15038
Y2H Prey Pooling
32296183
Intra MTURN Q8N3F0 DAZAP2 Homo sapiens Q15038
Y2H Array
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Polycystic Kidney Disease 2 With Or Without Polycystic Liver Disease

Polycystic Kidney Disease 2

PKD2

Polycystic Kidney Disease, Adult, Type Ii

Apkd2

Polycystic Kidney Disease, Type 2

Adpkd2

Adult Polycystic Kidney Disease Type 2

Autosomal Dominant Polycystic Kidney Disease 2

Pkd-2

Polycystic Kidney Disease Adult Type Ii

Polycystic Kidney Type 2 Autosomal Dominant Disease

Kidney Disease, Polycystic, Type 2
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS08825 MTURN Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Felis catus MTURN VGNC VGNC:102646
Mus musculus MTURN MGD MGI:1915485
Bos taurus MTURN VGNC VGNC:31755
Canis familiaris MTURN VGNC VGNC:54788
Rattus norvegicus MTURN RGD RGD:1549700
Macaca mulatta MTURN VGNC VGNC:75022
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