518A2
|
IC50 |
|
Cytotoxicity against human 518A2 cells assessed as inhibition of cell growth after 72 hrs by MTT assay
Cytotoxicity against human 518A2 cells assessed as inhibition of cell growth after 72 hrs by MTT assay
|
[PMID: 31958738]
|
518A2
|
IC50 |
|
Growth inhibition of human 518A2 cells after 72 hrs by MTT assay
Growth inhibition of human 518A2 cells after 72 hrs by MTT assay
|
[PMID: 27116710]
|
518A2
|
IC50 |
|
Cytotoxicity against human 518A2 cells after 72 hrs by MTT assay
Cytotoxicity against human 518A2 cells after 72 hrs by MTT assay
|
[PMID: 20731355]
|
786-0
|
GI50 |
0.1 μM
Compound: CA4, NSC 613729
|
Growth inhibition of human 786-0 cells after 48 hrs by SRB assay
Growth inhibition of human 786-0 cells after 48 hrs by SRB assay
|
[PMID: 24387982]
|
786-0
|
GI50 |
0.1 μM
Compound: 2, combretastatin A-4, CA-4, NSC 613729
|
Growth inhibition of human 786-0 cells after 48 hrs by SRB assay
Growth inhibition of human 786-0 cells after 48 hrs by SRB assay
|
[PMID: 22982122]
|
786-0
|
GI50 |
0.1 μM
Compound: CA4; NSC 613729
|
Cytotoxicity against human 786-0 cells by SRB assay
Cytotoxicity against human 786-0 cells by SRB assay
|
[PMID: 26257861]
|
786-0
|
GI50 |
|
Growth inhibition of human 786-0 cells after 48 hrs by sulforhodamine B assay
Growth inhibition of human 786-0 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 24388833]
|
A10
|
EC50 |
< 0.025 μM
Compound: CA-4
|
Inhibition of tubulin in rat A10 cells assessed as induction of cellular microtubule disassembly after 18 hrs by indirect immunofluorescence technique
Inhibition of tubulin in rat A10 cells assessed as induction of cellular microtubule disassembly after 18 hrs by indirect immunofluorescence technique
|
[PMID: 20006519]
|
A10
|
EC50 |
0.007 μM
Compound: 1, CA-4
|
Antiproliferative activity against rat A10 cells assessed as microtubule depolymerization after 18 to 24 hrs by indirect immunofluorescence technique
Antiproliferative activity against rat A10 cells assessed as microtubule depolymerization after 18 to 24 hrs by indirect immunofluorescence technique
|
[PMID: 19894742]
|
A10
|
IC50 |
|
Growth inhibition of rat A10 cells after 48 hrs by MTT assay
Growth inhibition of rat A10 cells after 48 hrs by MTT assay
|
[PMID: 22044164]
|
A10
|
EC50 |
|
Induction of interphase microtubule depolymerization in rat A10 cells after 18 to 24 hrs by indirect immunofluorescence assay
Induction of interphase microtubule depolymerization in rat A10 cells after 18 to 24 hrs by indirect immunofluorescence assay
|
[PMID: 23332369]
|
A10
|
EC50 |
|
Induction of microtubule depolymerization in rat A10 cells after 18 hrs by indirect immunofluorescence assay
Induction of microtubule depolymerization in rat A10 cells after 18 hrs by indirect immunofluorescence assay
|
[PMID: 23895532]
|
A10
|
EC50 |
|
Induction of microtubule depolymerization in rat A10 cells after 18 hrs by indirect immunofluorescence method
Induction of microtubule depolymerization in rat A10 cells after 18 hrs by indirect immunofluorescence method
|
[PMID: 30098869]
|
A10
|
EC50 |
|
Induction of microtubule depolymerization in rat A10 cells after 18 hrs by indirect immunofluorescence assay
Induction of microtubule depolymerization in rat A10 cells after 18 hrs by indirect immunofluorescence assay
|
[PMID: 25882519]
|
A2780
|
IC50 |
|
Antiproliferative activity against human A2780 cells assessed as reduction in cell viability after 48 hrs by MTT assay
Antiproliferative activity against human A2780 cells assessed as reduction in cell viability after 48 hrs by MTT assay
|
[PMID: 31185410]
|
A2780
|
IC50 |
0.004 μM
Compound: 1; CA-4
|
Antiproliferative activity against human A2780 cells after 48 hrs by MTT assay
Antiproliferative activity against human A2780 cells after 48 hrs by MTT assay
|
[PMID: 35065411]
|
A2780
|
IC50 |
|
Antiproliferative activity against human A2780 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
Antiproliferative activity against human A2780 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
|
[PMID: 33581556]
|
A2780
|
IC50 |
|
Antiproliferative activity against human A2780 cells by MTT assay
Antiproliferative activity against human A2780 cells by MTT assay
|
[PMID: 29126741]
|
A2780
|
IC50 |
0.006 μM
Compound: 1; CA-4
|
Antiproliferative activity against human A2780 cells after 48 hrs by MTT assay
Antiproliferative activity against human A2780 cells after 48 hrs by MTT assay
|
[PMID: 29306206]
|
A2780
|
IC50 |
|
Cytotoxicity against human A2780 cells assessed as cell viability after 48 hrs by MTT assay
Cytotoxicity against human A2780 cells assessed as cell viability after 48 hrs by MTT assay
|
[PMID: 27149641]
|
A2780
|
IC50 |
|
Antiproliferative activity against human A2780 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
Antiproliferative activity against human A2780 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
|
[PMID: 34649064]
|
A2780
|
IC50 |
|
Antiproliferative activity against human A2780 cells measured after 48 hrs by MTT assay
Antiproliferative activity against human A2780 cells measured after 48 hrs by MTT assay
|
[PMID: 27721152]
|
A2780
|
IC50 |
|
Antiproliferative activity against human A2780 cells after 5 days by MTT assay
Antiproliferative activity against human A2780 cells after 5 days by MTT assay
|
[PMID: 19837594]
|
A2780
|
IC50 |
|
Antiproliferative activity against human A2780 cells assessed as reduction in cell viability measured after 48 hrs by MTT assay
Antiproliferative activity against human A2780 cells assessed as reduction in cell viability measured after 48 hrs by MTT assay
|
[PMID: 32339854]
|
A2780
|
IC50 |
|
Antiproliferative activity against human A2780 cells after 48 hrs by MTT assay
Antiproliferative activity against human A2780 cells after 48 hrs by MTT assay
|
[PMID: 28792756]
|
A2780
|
IC50 |
|
Antiproliferative activity against human A2780 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
Antiproliferative activity against human A2780 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
|
[PMID: 33618157]
|
A2780
|
IC50 |
|
Antiproliferative activity against human A2780 cells assessed as cell viability after 48 hrs by MTT assay
Antiproliferative activity against human A2780 cells assessed as cell viability after 48 hrs by MTT assay
|
[PMID: 26974371]
|
A2780
|
IC50 |
|
Antiproliferative activity against cisplatin resistant human A2780 cells assessed as cell viability after 48 hrs by MTT assay
Antiproliferative activity against cisplatin resistant human A2780 cells assessed as cell viability after 48 hrs by MTT assay
|
[PMID: 26974371]
|
A2780
|
IC50 |
|
Antiproliferative activity against paclitaxel-resistant human A2780 cells assessed as reduction in cell growth after 48 hrs by MTT assay
Antiproliferative activity against paclitaxel-resistant human A2780 cells assessed as reduction in cell growth after 48 hrs by MTT assay
|
[PMID: 33022479]
|
A-375
|
IC50 |
0.21 μM
Compound: Combretastatin A-4
|
Cytotoxicity against human A375 cells after 48 hrs by MTT assay
Cytotoxicity against human A375 cells after 48 hrs by MTT assay
|
[PMID: 30108703]
|
A-375
|
IC50 |
0.21 μM
Compound: Combretastatin-A4
|
Cytotoxicity against human A375 cells after 48 hrs by MTT assay
Cytotoxicity against human A375 cells after 48 hrs by MTT assay
|
[PMID: 27487568]
|
A-375
|
IC50 |
0.21 μM
Compound: 2a, CA-4
|
Cytotoxicity against human A375 cells after 48 hrs by MTT assay
Cytotoxicity against human A375 cells after 48 hrs by MTT assay
|
[PMID: 22543234]
|
A-375
|
IC50 |
|
Antiproliferative activity against human A375 after 48 hrs by spectrophotometry
Antiproliferative activity against human A375 after 48 hrs by spectrophotometry
|
[PMID: 21774499]
|
A-431
|
EC50 |
|
Cell cycle arrest in A431 cells by accumulation at G2/M phase
Cell cycle arrest in A431 cells by accumulation at G2/M phase
|
[PMID: 16377187]
|
A-431
|
EC50 |
|
Cell cycle arrest in A431 cells by accumulation at G2/M phase cell
Cell cycle arrest in A431 cells by accumulation at G2/M phase cell
|
[PMID: 16198562]
|
A-431
|
IC50 |
0.25 μM
Compound: 1a; CA-4
|
Cytotoxicity against human A431 cells after 48 hrs by MTT assay
Cytotoxicity against human A431 cells after 48 hrs by MTT assay
|
[PMID: 29291446]
|
A-431
|
IC50 |
|
Antiproliferative activity against human A431 after 48 hrs by spectrophotometry
Antiproliferative activity against human A431 after 48 hrs by spectrophotometry
|
[PMID: 21774499]
|
A498
|
GI50 |
0.006 μM
Compound: CA4, NSC 613729
|
Growth inhibition of human A498 cells after 48 hrs by SRB assay
Growth inhibition of human A498 cells after 48 hrs by SRB assay
|
[PMID: 24387982]
|
A498
|
GI50 |
0.006 μM
Compound: 2, combretastatin A-4, CA-4, NSC 613729
|
Growth inhibition of human A498 cells after 48 hrs by SRB assay
Growth inhibition of human A498 cells after 48 hrs by SRB assay
|
[PMID: 22982122]
|
A498
|
GI50 |
0.006 μM
Compound: CA4; NSC 613729
|
Cytotoxicity against human A498 cells by SRB assay
Cytotoxicity against human A498 cells by SRB assay
|
[PMID: 26257861]
|
A498
|
GI50 |
|
Growth inhibition of human A498 cells after 48 hrs by sulforhodamine B assay
Growth inhibition of human A498 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 27031215]
|
A498
|
GI50 |
50.1 nM
Compound: 1, CA-4
|
Cytotoxicity against human A498 cells after 48 hrs by sulforhodamine B assay
Cytotoxicity against human A498 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 21920767]
|
A498
|
GI50 |
|
Growth inhibition of human A498 cells after 48 hrs by sulforhodamine B assay
Growth inhibition of human A498 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 24388833]
|
A549
|
IC50 |
> 10 μM
Compound: 2, CSA4
|
Antiproliferative activity against human A549 cells assessed as growth inhibition after 48 hrs by MTT assay
Antiproliferative activity against human A549 cells assessed as growth inhibition after 48 hrs by MTT assay
|
[PMID: 22044164]
|
A549
|
IC50 |
|
Cytotoxicity against human A549 cells assessed as growth inhibition after 48 hrs by MTT assay
Cytotoxicity against human A549 cells assessed as growth inhibition after 48 hrs by MTT assay
|
[PMID: 23214452]
|
A549
|
IC50 |
> 20 μM
Compound: 1a; CA-4
|
Cytotoxicity against human A549 cells after 48 hrs by MTT assay
Cytotoxicity against human A549 cells after 48 hrs by MTT assay
|
[PMID: 29291446]
|
A549
|
IC50 |
|
Antiproliferative activity against human A549 cells after 72 hrs by XTT assay
Antiproliferative activity against human A549 cells after 72 hrs by XTT assay
|
[PMID: 30216850]
|
A549
|
IC50 |
0.003 μM
Compound: II, CA-4
|
Cytotoxicity against human A549 cells after 72 hrs by XTT assay
Cytotoxicity against human A549 cells after 72 hrs by XTT assay
|
[PMID: 19939521]
|
A549
|
IC50 |
|
Cytotoxicity against human A549 cells after 72 hrs by XTT assay
Cytotoxicity against human A549 cells after 72 hrs by XTT assay
|
[PMID: 19647439]
|
A549
|
IC50 |
|
Cytotoxicity against human A549 cells after 72 hrs by XTT assay
Cytotoxicity against human A549 cells after 72 hrs by XTT assay
|
[PMID: 18790642]
|
A549
|
IC50 |
|
Cytotoxicity against human A549 cells after 72 hrs by XTT method
Cytotoxicity against human A549 cells after 72 hrs by XTT method
|
[PMID: 18502133]
|
A549
|
IC50 |
|
Cytotoxicity against human A549 cells assessed as cell viability after 72 hrs by resazurin reduction assay
Cytotoxicity against human A549 cells assessed as cell viability after 72 hrs by resazurin reduction assay
|
[PMID: 26599530]
|
A549
|
IC50 |
|
Cytotoxicity against human A549 cells after 72 hrs by resazurin based fluorescence assay
Cytotoxicity against human A549 cells after 72 hrs by resazurin based fluorescence assay
|
[PMID: 24669888]
|
A549
|
IC50 |
|
Antiproliferative activity against human A549 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
Antiproliferative activity against human A549 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
|
[PMID: 33581556]
|
A549
|
IC50 |
|
Antiproliferative activity against human A549 cells assessed as reduction in cell viability after 48 hrs by MTT assay
Antiproliferative activity against human A549 cells assessed as reduction in cell viability after 48 hrs by MTT assay
|
[PMID: 31185410]
|
A549
|
IC50 |
|
Growth inhibition of human A549 cells after 48 hrs by MTT assay
Growth inhibition of human A549 cells after 48 hrs by MTT assay
|
[PMID: 29509413]
|
A549
|
GI50 |
0.0047 μM
Compound: 42; CA4
|
Cytotoxicity against human A549 cells incubated for 52 hrs in oxic condition by sulforhodamine B assay
Cytotoxicity against human A549 cells incubated for 52 hrs in oxic condition by sulforhodamine B assay
|
[PMID: 32196334]
|
A549
|
IC50 |
|
Cytotoxicity against human A549 cells assessed as cell viability after 48 hrs by MTT assay
Cytotoxicity against human A549 cells assessed as cell viability after 48 hrs by MTT assay
|
[PMID: 27149641]
|
A549
|
IC50 |
0.005 μM
Compound: 8; CA-4
|
Antiproliferative activity against human A549 cells assessed as cell growth inhibition after 72 hrs by SRB assay
Antiproliferative activity against human A549 cells assessed as cell growth inhibition after 72 hrs by SRB assay
|
[PMID: 34454126]
|
A549
|
IC50 |
0.006 μM
Compound: 1; CA-4
|
Antiproliferative activity against human A549 cells after 48 hrs by MTT assay
Antiproliferative activity against human A549 cells after 48 hrs by MTT assay
|
[PMID: 35065411]
|
A549
|
GI50 |
0.0061 μM
Compound: 42; CA4
|
Cytotoxicity against human A549 cells incubated for 4 hrs in anoxic condition followed by oxic exposure for 48 hrs by sulforhodamine B assay
Cytotoxicity against human A549 cells incubated for 4 hrs in anoxic condition followed by oxic exposure for 48 hrs by sulforhodamine B assay
|
[PMID: 32196334]
|
A549
|
IC50 |
|
Antiproliferative activity against human A549 cells assessed as reduction in cell viability incubated for 48 hrs by MTS assay
Antiproliferative activity against human A549 cells assessed as reduction in cell viability incubated for 48 hrs by MTS assay
|
[PMID: 35635956]
|
A549
|
IC50 |
|
Antiproliferative activity against human A549 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
Antiproliferative activity against human A549 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
|
[PMID: 34649064]
|
A549
|
IC50 |
|
Cytotoxicity against human A549 cells after 72 hrs by MTT assay
Cytotoxicity against human A549 cells after 72 hrs by MTT assay
|
[PMID: 25462279]
|
A549
|
IC50 |
0.009 μM
Compound: 1; CA-4
|
Cytotoxicity against human A549 cells assessed as reduction in cell viability after 24 hrs by MTT assay
Cytotoxicity against human A549 cells assessed as reduction in cell viability after 24 hrs by MTT assay
|
[PMID: 27994764]
|
A549
|
IC50 |
0.009 μM
Compound: 1; CA-4
|
Antiproliferative activity against human A549 cells after 72 hrs by MTT assay
Antiproliferative activity against human A549 cells after 72 hrs by MTT assay
|
[PMID: 30530194]
|
A549
|
IC50 |
|
Antiproliferative activity against human A549 cells measured after 48 hrs by MTT assay
Antiproliferative activity against human A549 cells measured after 48 hrs by MTT assay
|
[PMID: 27721152]
|
A549
|
IC50 |
|
Cytotoxicity against human A549 cells assessed as growth inhibition after 72 hrs by MTT assay
Cytotoxicity against human A549 cells assessed as growth inhibition after 72 hrs by MTT assay
|
[PMID: 28174064]
|
A549
|
IC50 |
0.012 μM
Compound: 2; CA-4
|
Antiproliferative activity against human A549 cells assessed as reduction in cell viability after 72 hrs by MTT assay
Antiproliferative activity against human A549 cells assessed as reduction in cell viability after 72 hrs by MTT assay
|
10.1039/C5MD00150A
|
A549
|
IC50 |
|
Antiproliferative activity against human A549 cells measured after 72 hrs by MTT assay
Antiproliferative activity against human A549 cells measured after 72 hrs by MTT assay
|
[PMID: 31787361]
|
A549
|
IC50 |
|
Cytotoxicity against human A549/CDDP cells assessed as growth inhibition after 48 hrs by MTT assay
Cytotoxicity against human A549/CDDP cells assessed as growth inhibition after 48 hrs by MTT assay
|
[PMID: 27149641]
|
A549
|
IC50 |
|
Antiproliferative activity against human A549 assessed as reduction in cell viability measured after 48 hrs by MTT assay
Antiproliferative activity against human A549 assessed as reduction in cell viability measured after 48 hrs by MTT assay
|
[PMID: 34175541]
|
A549
|
GI50 |
0.015 μM
Compound: 2, combretastatin A-4, CA-4, NSC 613729
|
Growth inhibition of human A549 cells after 48 hrs by SRB assay
Growth inhibition of human A549 cells after 48 hrs by SRB assay
|
[PMID: 22982122]
|
A549
|
IC50 |
0.016 μM
Compound: 2; CA-4
|
Antiproliferative activity against human A549 cells after 72 hrs by MTT assay
Antiproliferative activity against human A549 cells after 72 hrs by MTT assay
|
[PMID: 30245397]
|
A549
|
GI50 |
0.016 μM
Compound: CA4, NSC 613729
|
Growth inhibition of human A549 cells after 48 hrs by SRB assay
Growth inhibition of human A549 cells after 48 hrs by SRB assay
|
[PMID: 24387982]
|
A549
|
GI50 |
0.016 μM
Compound: CA4; NSC 613729
|
Cytotoxicity against human A549 cells by SRB assay
Cytotoxicity against human A549 cells by SRB assay
|
[PMID: 26257861]
|
A549
|
GI50 |
|
Growth inhibition of human A549/ATCC cells after 48 hrs by sulforhodamine B assay
Growth inhibition of human A549/ATCC cells after 48 hrs by sulforhodamine B assay
|
[PMID: 27031215]
|
A549
|
GI50 |
|
Antiproliferative activity against human A549 cells after 48 hrs by MTT assay
Antiproliferative activity against human A549 cells after 48 hrs by MTT assay
|
10.1039/C5MD00139K
|
A549
|
IC50 |
|
Antiproliferative activity against human A549 cells assessed as cell growth inhibition after 48 hrs by MTT assay
Antiproliferative activity against human A549 cells assessed as cell growth inhibition after 48 hrs by MTT assay
|
[PMID: 33895499]
|
A549
|
IC50 |
|
Antiproliferative activity against human A549 cells assessed as reduction in cell growth after 48 hrs by MTT assay
Antiproliferative activity against human A549 cells assessed as reduction in cell growth after 48 hrs by MTT assay
|
[PMID: 33022479]
|
A549
|
IC50 |
|
Antiproliferative activity against human A549 cells measured after 48 hrs by MTT assay
Antiproliferative activity against human A549 cells measured after 48 hrs by MTT assay
|
[PMID: 32717486]
|
A549
|
IC50 |
0.027 μM
Compound: 2; CA-4
|
Antiproliferative activity against human A549 cells assessed as inhibition of cell growth measured after 48 hrs by MTT assay
Antiproliferative activity against human A549 cells assessed as inhibition of cell growth measured after 48 hrs by MTT assay
|
[PMID: 36334455]
|
A549
|
IC50 |
|
Cytotoxicity against human A549 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay
Cytotoxicity against human A549 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay
|
[PMID: 35964428]
|
A549
|
IC50 |
0.037 μM
Compound: CA-4; 2
|
Antiproliferative activity against human A549 cells after 72 hrs by MTT assay
Antiproliferative activity against human A549 cells after 72 hrs by MTT assay
|
[PMID: 30176537]
|
A549
|
IC50 |
|
Antiproliferative activity against human A549 cells measured after 48 hrs by MTT assay
Antiproliferative activity against human A549 cells measured after 48 hrs by MTT assay
|
[PMID: 35551039]
|
A549
|
IC50 |
|
Cytotoxicity against human A549 cells assessed as reduction in cell viability measured after 24 hrs by MTT assay
Cytotoxicity against human A549 cells assessed as reduction in cell viability measured after 24 hrs by MTT assay
|
[PMID: 35447432]
|
A549
|
IC50 |
|
Cytotoxicity against human A549 cells assessed as reduction in cell viability by MTT assay
Cytotoxicity against human A549 cells assessed as reduction in cell viability by MTT assay
|
[PMID: 33010448]
|
A549
|
IC50 |
0.051 μM
Compound: 1; CA-4
|
Cytotoxicity against human A549 cells after 48 hrs by MTT assay
Cytotoxicity against human A549 cells after 48 hrs by MTT assay
|
[PMID: 26970659]
|
A549
|
IC50 |
|
Cytotoxicity against human A549 cells after 48 hrs by MTT assay
Cytotoxicity against human A549 cells after 48 hrs by MTT assay
|
[PMID: 25192811]
|
A549
|
GI50 |
0.056 μM
Compound: Combretastatin
|
Antiproliferative activity against human A549 cells after 48 hrs by SRB cell proliferation assay
Antiproliferative activity against human A549 cells after 48 hrs by SRB cell proliferation assay
|
[PMID: 29089233]
|
A549
|
IC50 |
0.058 μM
Compound: 2A; CA-4
|
Antiproliferative activity against human A549 cells after 48 hrs by MTT assay
Antiproliferative activity against human A549 cells after 48 hrs by MTT assay
|
[PMID: 28034647]
|
A549
|
IC50 |
0.058 μM
Compound: 1; CA-4
|
Antiproliferative activity against human A549 cells assessed as reduction in cell growth incubated for 72 hrs by MTT assay
Antiproliferative activity against human A549 cells assessed as reduction in cell growth incubated for 72 hrs by MTT assay
|
[PMID: 33421913]
|
A549
|
GI50 |
|
Antiproliferative activity against human A549 cells after 48 hrs by sulforhodamine B assay
Antiproliferative activity against human A549 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 27515320]
|
A549
|
GI50 |
|
Antiproliferative activity against human A549 cells assessed as cell growth inhibition by SRB assay
Antiproliferative activity against human A549 cells assessed as cell growth inhibition by SRB assay
|
[PMID: 26242242]
|
A549
|
IC50 |
0.09 μg/mL
Compound: 1, CA-4
|
Antiproliferative activity against human A549 cells after 48 hrs by MTT assay
Antiproliferative activity against human A549 cells after 48 hrs by MTT assay
|
[PMID: 21440448]
|
A549
|
IC50 |
|
Antiproliferative activity against human A549 cells after 48 hrs by MTT assay
Antiproliferative activity against human A549 cells after 48 hrs by MTT assay
|
[PMID: 22512906]
|
A549
|
IC50 |
|
Antiproliferative activity against human A549 cells after 48 hrs by MTT assay
Antiproliferative activity against human A549 cells after 48 hrs by MTT assay
|
[PMID: 24909678]
|
A549
|
IC50 |
0.11 μM
Compound: Combretastatin A-4
|
Cytotoxicity against human A549 cells after 48 hrs by MTT assay
Cytotoxicity against human A549 cells after 48 hrs by MTT assay
|
[PMID: 30108703]
|
A549
|
IC50 |
0.11 μM
Compound: Combretastatin-A4
|
Cytotoxicity against human A549 cells after 48 hrs by MTT assay
Cytotoxicity against human A549 cells after 48 hrs by MTT assay
|
[PMID: 27487568]
|
A549
|
IC50 |
0.11 μM
Compound: 2a, CA-4
|
Cytotoxicity against human A549 cells after 48 hrs by MTT assay
Cytotoxicity against human A549 cells after 48 hrs by MTT assay
|
[PMID: 22543234]
|
A549
|
IC50 |
|
Antiproliferative activity against human A549 cells by MTT assay
Antiproliferative activity against human A549 cells by MTT assay
|
[PMID: 30502686]
|
A549
|
IC50 |
|
Antiproliferative activity against human A549 cells assessed as reduction in cell viability after 24 hrs by MTT assay
Antiproliferative activity against human A549 cells assessed as reduction in cell viability after 24 hrs by MTT assay
|
[PMID: 25828827]
|
A549
|
IC50 |
|
Antiproliferative activity against human A549 cells after 24 hrs by MTT assay
Antiproliferative activity against human A549 cells after 24 hrs by MTT assay
|
[PMID: 30606674]
|
A549
|
GI50 |
|
Antiproliferative activity against human A549 cells assessed as cell viability after 72 hrs by MTT assay
Antiproliferative activity against human A549 cells assessed as cell viability after 72 hrs by MTT assay
|
[PMID: 31865012]
|
A549
|
IC50 |
0.18 μM
Compound: CA-4;1a
|
Antiproliferative activity against human A549 cells assessed as reduction in cell viability after 72 hrs by MTT assay
Antiproliferative activity against human A549 cells assessed as reduction in cell viability after 72 hrs by MTT assay
|
[PMID: 33550186]
|
A549
|
IC50 |
|
Antiproliferative activity against human A549 cells after 72 hrs by MTT assay
Antiproliferative activity against human A549 cells after 72 hrs by MTT assay
|
[PMID: 30633509]
|
A549
|
IC50 |
|
Antiproliferative activity against human A549 cells incubated for 48 hrs by MTT assay
Antiproliferative activity against human A549 cells incubated for 48 hrs by MTT assay
|
[PMID: 32035399]
|
A549
|
IC50 |
|
Cytotoxicity against human A549 cells assessed as growth inhibition after 48 hrs by MTT assay
Cytotoxicity against human A549 cells assessed as growth inhibition after 48 hrs by MTT assay
|
[PMID: 23809851]
|
A549
|
GI50 |
|
Growth inhibition of human A549 cells after 48 hrs by MTT assay
Growth inhibition of human A549 cells after 48 hrs by MTT assay
|
[PMID: 30041136]
|
A549
|
IC50 |
|
Antiproliferative activity against human A549 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
Antiproliferative activity against human A549 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
|
[PMID: 36252396]
|
A549
|
IC50 |
|
Cytotoxicity against human A549 cells after 48 hrs by MTT assay
Cytotoxicity against human A549 cells after 48 hrs by MTT assay
|
[PMID: 19665898]
|
A549
|
IC50 |
|
Cytotoxicity against human A549 cells after 72 hrs by MTT assay
Cytotoxicity against human A549 cells after 72 hrs by MTT assay
|
[PMID: 28622907]
|
A549
|
IC50 |
|
Antiproliferative activity against human A549 cells after 72 hrs by MTT assay
Antiproliferative activity against human A549 cells after 72 hrs by MTT assay
|
[PMID: 29407949]
|
A549
|
IC50 |
0.46 μg/mL
Compound: 2, CA-4
|
Antiproliferative activity against human A549 cells after 48 hrs by MTT assay
Antiproliferative activity against human A549 cells after 48 hrs by MTT assay
|
[PMID: 24916028]
|
A549
|
IC50 |
|
Antiproliferative activity against human A549 cells after 48 hrs by MTT assay
Antiproliferative activity against human A549 cells after 48 hrs by MTT assay
|
[PMID: 25703297]
|
A549
|
IC50 |
|
Anticancer activity against human A549 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay
Anticancer activity against human A549 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay
|
[PMID: 31954880]
|
A549
|
IC50 |
0.53 μg/mL
Compound: CA-4
|
Antiproliferative activity against human A549 cells after 48 hrs by MTT assay
Antiproliferative activity against human A549 cells after 48 hrs by MTT assay
|
[PMID: 22503741]
|
A549
|
IC50 |
0.55 μg/mL
Compound: CA-4
|
Antiproliferative activity against human A549 cells after 48 hrs by MTT assay
Antiproliferative activity against human A549 cells after 48 hrs by MTT assay
|
[PMID: 22261027]
|
A549
|
IC50 |
0.55 μM
Compound: 1, CA-4
|
Cytotoxicity against human A549 cells after 48 hrs by MTT assay
Cytotoxicity against human A549 cells after 48 hrs by MTT assay
|
10.1039/C2MD20085F
|
A549
|
IC50 |
|
Antiproliferative activity against human A549 cells assessed as reduction in cell growth measured after 72 hrs by MTT assay
Antiproliferative activity against human A549 cells assessed as reduction in cell growth measured after 72 hrs by MTT assay
|
[PMID: 31830637]
|
A549
|
IC50 |
|
Antiproliferative activity against human A549 cells after 48 hrs by MTT assay
Antiproliferative activity against human A549 cells after 48 hrs by MTT assay
|
[PMID: 34311158]
|
A549
|
GI50 |
|
Antiproliferative activity against human A549 cells incubated for 48 hrs by MTT assay
Antiproliferative activity against human A549 cells incubated for 48 hrs by MTT assay
|
[PMID: 32832031]
|
A549
|
IC50 |
1.15 μM
Compound: 1; CA-4
|
Antiproliferative activity against human A549 cells after 24 hrs by SRB assay
Antiproliferative activity against human A549 cells after 24 hrs by SRB assay
|
[PMID: 29268127]
|
A549
|
IC50 |
|
Cytotoxicity against human A549 cells after 48 hrs by MTT assay
Cytotoxicity against human A549 cells after 48 hrs by MTT assay
|
10.1039/C3MD00372H
|
A549
|
GI50 |
1200 nM
Compound: 1, CA-4
|
Cytotoxicity against human A549 cells after 48 hrs by sulforhodamine B assay
Cytotoxicity against human A549 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 21920767]
|
A549
|
IC50 |
|
Antiproliferative activity against human A549 cells after 2 days by MTT assay
Antiproliferative activity against human A549 cells after 2 days by MTT assay
|
[PMID: 29432949]
|
A549
|
IC50 |
130.384 μM
Compound: CA-4
|
Antiproliferative activity against cisplatin resistant human A549 cells assessed as reduction in cell growth after 48 hrs by MTT assay
Antiproliferative activity against cisplatin resistant human A549 cells assessed as reduction in cell growth after 48 hrs by MTT assay
|
[PMID: 33022479]
|
A549
|
GI50 |
|
Growth inhibition of human A549/ATCC cells after 48 hrs by sulforhodamine B assay
Growth inhibition of human A549/ATCC cells after 48 hrs by sulforhodamine B assay
|
[PMID: 24388833]
|
A549
|
IC50 |
180 nM
Compound: 1a, CA-4
|
Growth inhibition of human A549 cells after 72 hrs by MTT assay
Growth inhibition of human A549 cells after 72 hrs by MTT assay
|
[PMID: 25025853]
|
A549
|
IC50 |
|
Cytotoxicity against human A549 cells after 72 hrs by MTT assay
Cytotoxicity against human A549 cells after 72 hrs by MTT assay
|
[PMID: 23445496]
|
A549
|
IC50 |
180 nM
Compound: CA-4, 1a, 1
|
Antiproliferative activity against human A549 cells after 72 hrs by MTT assay
Antiproliferative activity against human A549 cells after 72 hrs by MTT assay
|
[PMID: 23117171]
|
A549
|
IC50 |
|
Antiproliferative activity against human A549 cells assessed as growth inhibition after 72 hrs by MTT assay
Antiproliferative activity against human A549 cells assessed as growth inhibition after 72 hrs by MTT assay
|
[PMID: 22578111]
|
A549
|
IC50 |
|
Cytotoxicity against human A549 cells after 72 hrs by MTT assay
Cytotoxicity against human A549 cells after 72 hrs by MTT assay
|
[PMID: 22136312]
|
A549
|
IC50 |
|
Antiproliferative activity against human A549 cells assessed as growth inhibition after 72 hrs by MTT assay
Antiproliferative activity against human A549 cells assessed as growth inhibition after 72 hrs by MTT assay
|
[PMID: 21663319]
|
A549
|
IC50 |
|
Antiproliferative activity against human A549 cells after 72 hrs by MTT assay
Antiproliferative activity against human A549 cells after 72 hrs by MTT assay
|
[PMID: 20420439]
|
A549
|
IC50 |
|
Antiproliferative activity against human A549 cells after 72 hrs by resazurin-based fluorescence assay
Antiproliferative activity against human A549 cells after 72 hrs by resazurin-based fluorescence assay
|
[PMID: 29202409]
|
A549
|
IC50 |
180 nM
Compound: 1a, CA-4
|
Antiproliferative activity against human A549 cells after 72 hrs by (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide test
Antiproliferative activity against human A549 cells after 72 hrs by (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide test
|
[PMID: 25785605]
|
A549
|
IC50 |
2.78 μM
Compound: Combretastatin A-4
|
Antiproliferative activity against human A549 cells incubated for 24 hrs by MTT assay
Antiproliferative activity against human A549 cells incubated for 24 hrs by MTT assay
|
[PMID: 32992133]
|
A549
|
IC50 |
|
Antiproliferative activity against human A549 cells after 24 to 48 hrs by CKK8 assay
Antiproliferative activity against human A549 cells after 24 to 48 hrs by CKK8 assay
|
[PMID: 25105922]
|
A549
|
GI50 |
|
Growth inhibition of human A549 cells assessed as inhibition of cell proliferation after 24 hrs by MTT assay
Growth inhibition of human A549 cells assessed as inhibition of cell proliferation after 24 hrs by MTT assay
|
[PMID: 26070164]
|
A549
|
IC50 |
|
Antiproliferative activity against human A549 cells measured after 48 hrs by MTT assay
Antiproliferative activity against human A549 cells measured after 48 hrs by MTT assay
|
[PMID: 36150341]
|
A549
|
IC50 |
|
Antiproliferative activity against human A549 cells after 72 hrs by CellTiter Glo assay
Antiproliferative activity against human A549 cells after 72 hrs by CellTiter Glo assay
|
[PMID: 35797900]
|
A549
|
IC50 |
|
Antiproliferative activity against human A549 cells assessed as cell viability after 24 hrs by Celltiter-Glo assay
Antiproliferative activity against human A549 cells assessed as cell viability after 24 hrs by Celltiter-Glo assay
|
[PMID: 33038796]
|
A549
|
IC50 |
|
Antiproliferative activity against human A549 cells after 72 hrs by MTS assay
Antiproliferative activity against human A549 cells after 72 hrs by MTS assay
|
[PMID: 30525602]
|
A549
|
IC50 |
|
Cytotoxicity against human A549 cells assessed as reduction in cell viability incubated for 72 hrs by MTS assay
Cytotoxicity against human A549 cells assessed as reduction in cell viability incubated for 72 hrs by MTS assay
|
[PMID: 31401010]
|
A549
|
IC50 |
|
Antiproliferative activity against CA-4-resistant human A549 cells measured after 72 hrs by MTT assay
Antiproliferative activity against CA-4-resistant human A549 cells measured after 72 hrs by MTT assay
|
[PMID: 27187864]
|
A549
|
IC50 |
3.64 nM
Compound: 1, CA-4
|
Cytotoxicity against human A549 cells after 72 hrs by CCK-8 assay
Cytotoxicity against human A549 cells after 72 hrs by CCK-8 assay
|
[PMID: 23360369]
|
A549
|
IC50 |
|
Antiproliferative activity against human A549 cells after 48 hrs by MTT assay
Antiproliferative activity against human A549 cells after 48 hrs by MTT assay
|
[PMID: 28792756]
|
A549
|
IC50 |
|
Antiproliferative activity against human A549 cells incubated for 48 hrs by MTS assay
Antiproliferative activity against human A549 cells incubated for 48 hrs by MTS assay
|
[PMID: 31541870]
|
A549
|
GI50 |
|
Antiproliferation activity against human A549 cells assessed as cell growth inhibition measured after 72 hrs by MTT assay
Antiproliferation activity against human A549 cells assessed as cell growth inhibition measured after 72 hrs by MTT assay
|
[PMID: 33201714]
|
A549
|
IC50 |
49.05 μM
Compound: 3; CA-4
|
Growth inhibition of human A549 cells incubated for 48 hrs by MTT assay
Growth inhibition of human A549 cells incubated for 48 hrs by MTT assay
|
[PMID: 27172319]
|
A549
|
IC50 |
|
Cytotoxicity against human A549 cells after 48 hrs by WST-8 assay
Cytotoxicity against human A549 cells after 48 hrs by WST-8 assay
|
[PMID: 22727370]
|
A549
|
IC50 |
|
Antiproliferative activity against human A549 cells after 48 hrs by sulforhodamine B assay
Antiproliferative activity against human A549 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 28684120]
|
A549
|
GI50 |
|
Antiproliferative activity against human A549 cells assessed as cell growth inhibition measured after 72 hrs by SRB assay
Antiproliferative activity against human A549 cells assessed as cell growth inhibition measured after 72 hrs by SRB assay
|
[PMID: 34917259]
|
A549
|
GI50 |
|
Antiproliferative activity against human A549 cells assessed as reduction in cell viability incubated for 72 hrs by SRB assay
Antiproliferative activity against human A549 cells assessed as reduction in cell viability incubated for 72 hrs by SRB assay
|
[PMID: 31938468]
|
A549
|
IC50 |
|
Cytotoxicity against human A549 cells after 48 hrs by MTT assay
Cytotoxicity against human A549 cells after 48 hrs by MTT assay
|
[PMID: 23356786]
|
A549
|
IC50 |
|
Antiproliferative activity against human A549 cells after 72 hrs by CCK-8 assay
Antiproliferative activity against human A549 cells after 72 hrs by CCK-8 assay
|
[PMID: 30108925]
|
A549
|
IC50 |
6.45 μM
Compound: Combretastatin
|
Antiproliferative activity in human A549 cells assessed as reduction in cell number incubated for 48 hrs by SRB assay
Antiproliferative activity in human A549 cells assessed as reduction in cell number incubated for 48 hrs by SRB assay
|
[PMID: 30108756]
|
A549
|
IC50 |
|
Antiproliferative activity against human A549 cells after 72 hrs by MTT assay
Antiproliferative activity against human A549 cells after 72 hrs by MTT assay
|
[PMID: 31610375]
|
A549
|
IC50 |
|
Antiproliferative activity against human A549 cells after 5 days by MTT assay
Antiproliferative activity against human A549 cells after 5 days by MTT assay
|
[PMID: 19837594]
|
A549
|
IC50 |
|
Growth inhibition of human A549 cells after 48 hrs by SRB assay
Growth inhibition of human A549 cells after 48 hrs by SRB assay
|
[PMID: 24900453]
|
A549
|
IC50 |
9.29 μM
Compound: CA-4; B
|
Antiproliferative activity against human A549 cells after 48 hrs by MTT assay
Antiproliferative activity against human A549 cells after 48 hrs by MTT assay
|
[PMID: 28774575]
|
A549
|
IC50 |
|
Antiproliferative activity against human A549 cells after 72 hrs by CCK8 assay
Antiproliferative activity against human A549 cells after 72 hrs by CCK8 assay
|
[PMID: 30006162]
|
A549/CDDP
|
IC50 |
|
Growth inhibition of human A549/CDDP cells after 48 hrs by MTT assay
Growth inhibition of human A549/CDDP cells after 48 hrs by MTT assay
|
[PMID: 29509413]
|
A549/TR
|
IC50 |
0.175 μM
Compound: 1; CA-4
|
Antiproliferative activity against human taxol-resistant A549/TR cells after 72 hrs by MTT assay
Antiproliferative activity against human taxol-resistant A549/TR cells after 72 hrs by MTT assay
|
[PMID: 30530194]
|
ACHN
|
IC50 |
|
Cytotoxicity against human ACHN cells after 48 hrs by MTT assay
Cytotoxicity against human ACHN cells after 48 hrs by MTT assay
|
[PMID: 25192811]
|
ACHN
|
GI50 |
0.006 μM
Compound: CA4, NSC 613729
|
Growth inhibition of human ACHN cells after 48 hrs by SRB assay
Growth inhibition of human ACHN cells after 48 hrs by SRB assay
|
[PMID: 24387982]
|
ACHN
|
GI50 |
0.006 μM
Compound: 2, combretastatin A-4, CA-4, NSC 613729
|
Growth inhibition of human ACHN cells after 48 hrs by SRB assay
Growth inhibition of human ACHN cells after 48 hrs by SRB assay
|
[PMID: 22982122]
|
ACHN
|
GI50 |
0.006 μM
Compound: CA4; NSC 613729
|
Cytotoxicity against human ACHN cells by SRB assay
Cytotoxicity against human ACHN cells by SRB assay
|
[PMID: 26257861]
|
ACHN
|
IC50 |
0.17 μM
Compound: 2a, CA-4
|
Cytotoxicity against human ACHN cells after 48 hrs by MTT assay
Cytotoxicity against human ACHN cells after 48 hrs by MTT assay
|
[PMID: 22543234]
|
ACHN
|
IC50 |
|
Antiproliferative activity against drug resistant ACHN cell line expressing MDR1 by Alamar Blue assay
Antiproliferative activity against drug resistant ACHN cell line expressing MDR1 by Alamar Blue assay
|
[PMID: 17286393]
|
ACHN
|
GI50 |
|
Growth inhibition of human ACHN cells after 48 hrs by sulforhodamine B assay
Growth inhibition of human ACHN cells after 48 hrs by sulforhodamine B assay
|
[PMID: 24388833]
|
AGS
|
IC50 |
0.04 μM
Compound: 1, CA-4
|
Cytotoxicity against human AGS cells assessed as growth inhibition after 48 hrs by MTT assay
Cytotoxicity against human AGS cells assessed as growth inhibition after 48 hrs by MTT assay
|
[PMID: 23566762]
|
AGS
|
IC50 |
|
Cytotoxicity against human AGS cells after 48 hrs by MTT assay
Cytotoxicity against human AGS cells after 48 hrs by MTT assay
|
[PMID: 24238904]
|
AU565
|
IC50 |
|
Antiproliferative activity against human AU565 after 48 hrs by spectrophotometry
Antiproliferative activity against human AU565 after 48 hrs by spectrophotometry
|
[PMID: 21774499]
|
B16
|
IC50 |
0.002 μM
Compound: 2, CA-4
|
Cytotoxicity against mouse B16 cells after 72 hrs by MTT assay
Cytotoxicity against mouse B16 cells after 72 hrs by MTT assay
|
[PMID: 21524832]
|
B16
|
IC50 |
|
Cytotoxicity against mouse B16 cells after 48 hrs by MTT assay
Cytotoxicity against mouse B16 cells after 48 hrs by MTT assay
|
[PMID: 23369686]
|
B16
|
IC50 |
0.003 μM
Compound: 1, CA4
|
Cytotoxicity against mouse B16 cells assessed as cell viability after 48 hrs by MTT assay
Cytotoxicity against mouse B16 cells assessed as cell viability after 48 hrs by MTT assay
|
[PMID: 22647220]
|
B16
|
IC50 |
|
Cytotoxicity against mouse B16 cells assessed as cell viability after 48 hrs by MTT test
Cytotoxicity against mouse B16 cells assessed as cell viability after 48 hrs by MTT test
|
[PMID: 18583138]
|
B16
|
IC50 |
0.003 μM
Compound: 1, CA-4
|
Cytotoxicity against mouse B16 cells after 72 hrs by MTT assay
Cytotoxicity against mouse B16 cells after 72 hrs by MTT assay
|
[PMID: 18226429]
|
B16
|
IC50 |
|
Cytotoxicity against mouse B16 cells assessed as reduction in cell viability after 48 hrs by MTT assay
Cytotoxicity against mouse B16 cells assessed as reduction in cell viability after 48 hrs by MTT assay
|
[PMID: 21112130]
|
B16
|
IC50 |
|
Cytotoxicity against mouse B16 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
Cytotoxicity against mouse B16 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
|
[PMID: 33479639]
|
B16-F10
|
IC50 |
|
Antiproliferative activity against mouse B16-F10 cells assessed as reduction in cell viability measured after 48 hrs by MTT assay
Antiproliferative activity against mouse B16-F10 cells assessed as reduction in cell viability measured after 48 hrs by MTT assay
|
[PMID: 34455231]
|
B16-F10
|
IC50 |
|
Antiproliferative activity against mouse B16-F10 cells assessed as reduction in cell viability measured after 48 hrs by CCK8 assay
Antiproliferative activity against mouse B16-F10 cells assessed as reduction in cell viability measured after 48 hrs by CCK8 assay
|
[PMID: 33280898]
|
B16-F10
|
IC50 |
0.4 μg/mL
Compound: 1, CA-4
|
Antiproliferative activity against mouse B16F10 cells after 48 hrs by MTT assay
Antiproliferative activity against mouse B16F10 cells after 48 hrs by MTT assay
|
[PMID: 21440448]
|
B16-F10
|
IC50 |
0.4 μg/mL
Compound: 2, CA-4
|
Antiproliferative activity against mouse B16F10 cells after 48 hrs by MTT based ELISA assay
Antiproliferative activity against mouse B16F10 cells after 48 hrs by MTT based ELISA assay
|
[PMID: 21783370]
|
B16-F10
|
IC50 |
0.42 μg/mL
Compound: 2, CA-4
|
Antiproliferative activity against mouse B16F10 cells after 48 hrs by MTT assay
Antiproliferative activity against mouse B16F10 cells after 48 hrs by MTT assay
|
[PMID: 24916028]
|
B16-F10
|
IC50 |
|
Antiproliferative activity against mouse B16F10 cells after 48 hrs by MTT assay
Antiproliferative activity against mouse B16F10 cells after 48 hrs by MTT assay
|
[PMID: 25703297]
|
B16-F10
|
IC50 |
0.75 μg/mL
Compound: CA-4
|
Antiproliferative activity against mouse B16F10 cells after 48 hrs by MTT assay
Antiproliferative activity against mouse B16F10 cells after 48 hrs by MTT assay
|
[PMID: 22192936]
|
Bel-7402
|
IC50 |
|
Cytotoxicity against human Bel7402 cells assessed as cell viability after 48 hrs by MTT assay
Cytotoxicity against human Bel7402 cells assessed as cell viability after 48 hrs by MTT assay
|
[PMID: 27149641]
|
Bel-7402
|
IC50 |
0.011 μM
Compound: 1; CA-4
|
Antiproliferative activity against human Bel-7402 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
Antiproliferative activity against human Bel-7402 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
|
[PMID: 33676300]
|
Bel-7402
|
IC50 |
0.011 μM
Compound: 1; CA-4
|
Antiproliferative activity against human Bel7402 cells after 72 hrs by MTT assay
Antiproliferative activity against human Bel7402 cells after 72 hrs by MTT assay
|
[PMID: 30530194]
|
Bel-7402
|
GI50 |
|
Antiproliferative activity against human Bel7402 cells after 48 hrs by MTT assay
Antiproliferative activity against human Bel7402 cells after 48 hrs by MTT assay
|
10.1039/C5MD00139K
|
Bel-7402
|
IC50 |
|
Antiproliferative activity against human Bel7402 cells measured after 48 hrs by MTT assay
Antiproliferative activity against human Bel7402 cells measured after 48 hrs by MTT assay
|
[PMID: 27721152]
|
Bel-7402
|
IC50 |
0.02 μM
Compound: 1; CA-4
|
Antiproliferative activity against human Bel7402 assessed as reduction in cell viability measured after 48 hrs by SRB assay
Antiproliferative activity against human Bel7402 assessed as reduction in cell viability measured after 48 hrs by SRB assay
|
[PMID: 27919655]
|
Bel-7402
|
IC50 |
0.058 μM
Compound: 1; CA-4
|
Antiproliferative activity against ADR-resistant human Bel-7402 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
Antiproliferative activity against ADR-resistant human Bel-7402 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
|
[PMID: 33676300]
|
Bel-7402
|
IC50 |
|
Antiproliferative activity against human Bel-7402 cells measured after 48 hrs by SRB assay
Antiproliferative activity against human Bel-7402 cells measured after 48 hrs by SRB assay
|
[PMID: 32113125]
|
Bel-7402
|
IC50 |
|
Cytotoxicity against human Bel7402 cells assessed as growth inhibition after 72 hrs by MTT assay
Cytotoxicity against human Bel7402 cells assessed as growth inhibition after 72 hrs by MTT assay
|
[PMID: 23708012]
|
Bel-7402
|
IC50 |
|
Anticancer activity against human Bel7402 cells after 72 hrs
Anticancer activity against human Bel7402 cells after 72 hrs
|
[PMID: 19713108]
|
Bel-7402
|
IC50 |
|
Antiproliferative activity against human Bel7402 cells after 72 hrs
Antiproliferative activity against human Bel7402 cells after 72 hrs
|
[PMID: 17034133]
|
BeWo
|
IC50 |
|
Cytotoxicity against human Bewo cells after 48 hrs by MTT assay
Cytotoxicity against human Bewo cells after 48 hrs by MTT assay
|
10.1039/C3MD00372H
|
BJ
|
IC50 |
28.6 nM
Compound: 7; CA-4
|
Cytotoxicity against human BJ cells assessed as reduction in cell viability incubated for 72 hrs by MTS assay
Cytotoxicity against human BJ cells assessed as reduction in cell viability incubated for 72 hrs by MTS assay
|
[PMID: 31401010]
|
BMEC
|
IC50 |
|
Cytotoxicity against BMEC by sulforhodamine B test
Cytotoxicity against BMEC by sulforhodamine B test
|
[PMID: 18783207]
|
BT-474
|
IC50 |
|
Cytotoxicity against human BT474 cells assessed as cell viability after 4 days by MTS assay
Cytotoxicity against human BT474 cells assessed as cell viability after 4 days by MTS assay
|
[PMID: 24210503]
|
BT-549
|
IC50 |
|
Cytotoxicity against human BT549 cells after 72 hrs by MTT assay
Cytotoxicity against human BT549 cells after 72 hrs by MTT assay
|
[PMID: 30472600]
|
BT-549
|
GI50 |
10 μM
Compound: 2, combretastatin A-4, CA-4, NSC 613729
|
Growth inhibition of human BT549 cells after 48 hrs by SRB assay
Growth inhibition of human BT549 cells after 48 hrs by SRB assay
|
[PMID: 22982122]
|
BT-549
|
IC50 |
|
Antiproliferative activity against human BT549 after 48 hrs by spectrophotometry
Antiproliferative activity against human BT549 after 48 hrs by spectrophotometry
|
[PMID: 21774499]
|
BXPC-3
|
IC50 |
|
Cytotoxicity against human BxPC3 cells assessed as growth inhibition after 72 hrs by MTT assay
Cytotoxicity against human BxPC3 cells assessed as growth inhibition after 72 hrs by MTT assay
|
[PMID: 23981529]
|
BXPC-3
|
GI50 |
0.39 μg/mL
Compound: 1a, CA4
|
Growth inhibition of human BxPC3 cells after 48 hrs by sulforhodamine B assay
Growth inhibition of human BxPC3 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 22324723]
|
BXPC-3
|
GI50 |
|
Growth inhibition of human BxPC3 cells after 48 hrs by sulforhodamine B assay
Growth inhibition of human BxPC3 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 19719153]
|
BXPC-3
|
GI50 |
0.39 μg/mL
Compound: Z-1b
|
Cytotoxicity against human BxPC3 cells after 48 hrs by sulforhodamine B assay
Cytotoxicity against human BxPC3 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 19709889]
|
BXPC-3
|
GI50 |
0.39 μg/mL
Compound: 1a, CA4
|
Cytotoxicity against human BxPC3 cells after 48 hrs by sulforhodamine B assay
Cytotoxicity against human BxPC3 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 16252907]
|
BXPC-3
|
GI50 |
0.39 μg/mL
Compound: 3, CA4
|
Antitumor activity against human BxPC3 cells by sulforhodamine B assay
Antitumor activity against human BxPC3 cells by sulforhodamine B assay
|
[PMID: 19228038]
|
BXPC-3
|
GI50 |
0.39 μM
Compound: CA4, combretastatin A4
|
Cytotoxicity against human BXPC3 cells after 48 hrs by SRB assay
Cytotoxicity against human BXPC3 cells after 48 hrs by SRB assay
|
[PMID: 18303849]
|
CA46
|
IC50 |
|
Antiproliferative activity against human CA46 cells assessed as reduction in cell viability after 72 hrs by MTT assay
Antiproliferative activity against human CA46 cells assessed as reduction in cell viability after 72 hrs by MTT assay
|
[PMID: 25050880]
|
CAKI-1
|
GI50 |
0.025 μM
Compound: 2, combretastatin A-4, CA-4, NSC 613729
|
Growth inhibition of human Caki1 cells after 48 hrs by SRB assay
Growth inhibition of human Caki1 cells after 48 hrs by SRB assay
|
[PMID: 22982122]
|
CAKI-1
|
GI50 |
|
Growth inhibition of human Caki1 cells after 48 hrs by sulforhodamine B assay
Growth inhibition of human Caki1 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 27031215]
|
CAKI-1
|
GI50 |
0.026 μM
Compound: CA4, NSC 613729
|
Growth inhibition of human CAKI-1 cells after 48 hrs by SRB assay
Growth inhibition of human CAKI-1 cells after 48 hrs by SRB assay
|
[PMID: 24387982]
|
CAKI-1
|
GI50 |
0.026 μM
Compound: CA4; NSC 613729
|
Cytotoxicity against human CAKI-1 cells by SRB assay
Cytotoxicity against human CAKI-1 cells by SRB assay
|
[PMID: 26257861]
|
CAKI-1
|
GI50 |
|
Growth inhibition of human CAKI-1 cells after 48 hrs by sulforhodamine B assay
Growth inhibition of human CAKI-1 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 24388833]
|
CAL-27
|
IC50 |
|
Antiproliferative activity against human CAL-27 cells assessed as cell growth inhibition incubated for 72 hrs by CCK-8 assay
Antiproliferative activity against human CAL-27 cells assessed as cell growth inhibition incubated for 72 hrs by CCK-8 assay
|
[PMID: 35576703]
|
Calu-1
|
IC50 |
2.78 μM
Compound: Combretastatin A-4
|
Antiproliferative activity against human Calu-1 cells incubated for 24 hrs by MTT assay
Antiproliferative activity against human Calu-1 cells incubated for 24 hrs by MTT assay
|
[PMID: 32992133]
|
Calu-6
|
IC50 |
|
Antiproliferative activity against human Calu6 after 48 hrs by spectrophotometry
Antiproliferative activity against human Calu6 after 48 hrs by spectrophotometry
|
[PMID: 21774499]
|
Cancer cell lines
|
IC50 |
30 nM
Compound: combretastatin A-4
|
Cell growth inhibition against HR, human gastric cancer cells using MTS assay
Cell growth inhibition against HR, human gastric cancer cells using MTS assay
|
[PMID: 12036364]
|
Cancer cell lines
|
IC50 |
8520 nM
Compound: combretastatin A-4
|
Cell growth inhibition against NUGC3 human stomach cancer cells using MTS assay
Cell growth inhibition against NUGC3 human stomach cancer cells using MTS assay
|
[PMID: 12036364]
|
CAPAN-1
|
IC50 |
|
Cytotoxicity against human Capan1 cells after 48 hrs by XTT assay
Cytotoxicity against human Capan1 cells after 48 hrs by XTT assay
|
[PMID: 30017114]
|
CCRF-CEM
|
IC50 |
> 100 μM
Compound: 2, CA-4
|
Cytotoxicity against human CEM cells by alamar blue assay
Cytotoxicity against human CEM cells by alamar blue assay
|
[PMID: 22137934]
|
CCRF-CEM
|
IC50 |
|
Cytotoxicity against human CEM cells after 72 hrs by MTT assay
Cytotoxicity against human CEM cells after 72 hrs by MTT assay
|
[PMID: 22676247]
|
CCRF-CEM
|
IC50 |
|
Cytotoxicity against human CEM cells assessed as growth inhibition after 72 hrs by MTT assay
Cytotoxicity against human CEM cells assessed as growth inhibition after 72 hrs by MTT assay
|
[PMID: 23708012]
|
CCRF-CEM
|
IC50 |
0.002 μM
Compound: 1, CA-4
|
Antiproliferative activity against human CEM cells after 2 days by coulter counter analysis
Antiproliferative activity against human CEM cells after 2 days by coulter counter analysis
|
[PMID: 22027100]
|
CCRF-CEM
|
IC50 |
0.002 μM
Compound: CA-4;1a
|
Antiproliferative activity against human CCRF-CEM cells assessed as reduction in cell viability after 72 hrs by MTT assay
Antiproliferative activity against human CCRF-CEM cells assessed as reduction in cell viability after 72 hrs by MTT assay
|
[PMID: 33550186]
|
CCRF-CEM
|
GI50 |
0.002 μM
Compound: 2, combretastatin A-4, CA-4, NSC 613729
|
Growth inhibition of human CCRF-CEM cells after 48 hrs by SRB assay
Growth inhibition of human CCRF-CEM cells after 48 hrs by SRB assay
|
[PMID: 22982122]
|
CCRF-CEM
|
IC50 |
|
Anticancer activity against human CCRF-CEM cells after 72 hrs
Anticancer activity against human CCRF-CEM cells after 72 hrs
|
[PMID: 19713108]
|
CCRF-CEM
|
GI50 |
0.003 μM
Compound: CA4, NSC 613729
|
Growth inhibition of human CCRF-CEM cells after 48 hrs by SRB assay
Growth inhibition of human CCRF-CEM cells after 48 hrs by SRB assay
|
[PMID: 24387982]
|
CCRF-CEM
|
GI50 |
0.003 μM
Compound: CA4; NSC 613729
|
Cytotoxicity against human CCRF-CEM cells by SRB assay
Cytotoxicity against human CCRF-CEM cells by SRB assay
|
[PMID: 26257861]
|
CCRF-CEM
|
IC50 |
0.708 nM
Compound: 7; CA-4
|
Cytotoxicity against human CCRF-CEM cells assessed as reduction in cell viability incubated for 72 hrs by MTS assay
Cytotoxicity against human CCRF-CEM cells assessed as reduction in cell viability incubated for 72 hrs by MTS assay
|
[PMID: 31401010]
|
CCRF-CEM
|
IC50 |
|
Antiproliferative activity against human CEM cells after 2 days by coulter counting
Antiproliferative activity against human CEM cells after 2 days by coulter counting
|
[PMID: 20579891]
|
CCRF-CEM
|
IC50 |
1.9 nM
Compound: 1a, CA-4
|
Cytotoxicity against human CEM/0 cells assessed as growth inhibition after 48 hrs by coulter counting analysis
Cytotoxicity against human CEM/0 cells assessed as growth inhibition after 48 hrs by coulter counting analysis
|
[PMID: 24164557]
|
CCRF-CEM
|
IC50 |
|
Cytotoxicity against human CEM cells after 2 days
Cytotoxicity against human CEM cells after 2 days
|
[PMID: 19736015]
|
CCRF-CEM
|
IC50 |
|
Antiproliferative activity against human CEM cells after 2 days
Antiproliferative activity against human CEM cells after 2 days
|
[PMID: 18755591]
|
CCRF-CEM
|
IC50 |
|
Antiproliferative effect against human CEM cells after 3 days
Antiproliferative effect against human CEM cells after 3 days
|
[PMID: 17419607]
|
CCRF-CEM
|
IC50 |
|
Antiproliferative activity against human CEM cells after 2 days by coulter counter method
Antiproliferative activity against human CEM cells after 2 days by coulter counter method
|
[PMID: 19663386]
|
CCRF-CEM
|
IC50 |
|
Growth inhibition of human CCRF-CEM cells after 72 hrs by MTT assay
Growth inhibition of human CCRF-CEM cells after 72 hrs by MTT assay
|
[PMID: 25025853]
|
CCRF-CEM
|
IC50 |
|
Antiproliferative activity against human CEM cells after 3 days by Coulter counter method
Antiproliferative activity against human CEM cells after 3 days by Coulter counter method
|
[PMID: 29220790]
|
CCRF-CEM
|
GI50 |
|
Growth inhibition of human CCRF-CEM cells after 48 hrs by sulforhodamine B assay
Growth inhibition of human CCRF-CEM cells after 48 hrs by sulforhodamine B assay
|
[PMID: 24388833]
|
CEM-DNR
|
IC50 |
|
Cytotoxicity against human CEM/DNR cells assessed as reduction in cell viability incubated for 72 hrs by MTS assay
Cytotoxicity against human CEM/DNR cells assessed as reduction in cell viability incubated for 72 hrs by MTS assay
|
[PMID: 31401010]
|
COLO 205
|
IC50 |
|
Antiproliferative activity against human COLO205 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
Antiproliferative activity against human COLO205 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
|
[PMID: 31174062]
|
COLO 205
|
IC50 |
|
Antiproliferative activity against human COLO205 cells assessed as reduction in cell viability by MTT assay
Antiproliferative activity against human COLO205 cells assessed as reduction in cell viability by MTT assay
|
[PMID: 31362922]
|
COLO 205
|
GI50 |
0.025 μM
Compound: 1; CA-4
|
Antiproliferative activity against human COLO 205 cells assessed as cell growth inhibition measured after 48 hrs by SRB assay
Antiproliferative activity against human COLO 205 cells assessed as cell growth inhibition measured after 48 hrs by SRB assay
|
[PMID: 27161282]
|
COLO 205
|
GI50 |
0.1 μM
Compound: CA4, NSC 613729
|
Growth inhibition of human COLO205 cells after 48 hrs by SRB assay
Growth inhibition of human COLO205 cells after 48 hrs by SRB assay
|
[PMID: 24387982]
|
COLO 205
|
GI50 |
0.1 μM
Compound: 2, combretastatin A-4, CA-4, NSC 613729
|
Growth inhibition of human COLO205 cells after 48 hrs by SRB assay
Growth inhibition of human COLO205 cells after 48 hrs by SRB assay
|
[PMID: 22982122]
|
COLO 205
|
GI50 |
0.1 μM
Compound: CA4; NSC 613729
|
Cytotoxicity against human COLO205 cells by SRB assay
Cytotoxicity against human COLO205 cells by SRB assay
|
[PMID: 26257861]
|
COLO 205
|
GI50 |
|
Growth inhibition of human COLO205 cells after 48 hrs by sulforhodamine B assay
Growth inhibition of human COLO205 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 27031215]
|
COLO 205
|
GI50 |
|
Growth inhibition of human COLO205 cells after 48 hrs by sulforhodamine B assay
Growth inhibition of human COLO205 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 24388833]
|
COLO 205
|
IC50 |
2756 nM
Compound: combretastatin A-4
|
Cell growth inhibition against colo 205 human colon cancer cells using tetrazolium dye reduction (MTS) assay
Cell growth inhibition against colo 205 human colon cancer cells using tetrazolium dye reduction (MTS) assay
|
[PMID: 12036364]
|
Colon 26
|
IC50 |
|
Antiproliferative activity against mouse Colon 26 cells measured after 72 hrs by MTT assay
Antiproliferative activity against mouse Colon 26 cells measured after 72 hrs by MTT assay
|
[PMID: 27187864]
|
Colon 26
|
IC50 |
18 nM
Compound: Combrestatin A-4
|
Growth inhibition of colon 26 adenocarcinoma cells by 50 %.
Growth inhibition of colon 26 adenocarcinoma cells by 50 %.
|
[PMID: 9685242]
|
CPT30 cell line
|
IC50 |
|
Inhibitory concentration against camptothecin (CPT) resistant cell line using tetrazolium dye reduction assay (MTT)
Inhibitory concentration against camptothecin (CPT) resistant cell line using tetrazolium dye reduction assay (MTT)
|
[PMID: 12467626]
|
CT26
|
IC50 |
|
Antiproliferative activity against mouse CT26 cells after 72 hrs by CCK8 assay
Antiproliferative activity against mouse CT26 cells after 72 hrs by CCK8 assay
|
[PMID: 30006162]
|
DLD-1
|
IC50 |
|
Growth inhibition of human DLD1 cells after 48 hrs by SRB assay
Growth inhibition of human DLD1 cells after 48 hrs by SRB assay
|
[PMID: 24900453]
|
DLD-1
|
IC50 |
36 nM
Compound: combretastatin A-4
|
Cell growth inhibition against DLD-1 human colon cancer cells using MTS assay
Cell growth inhibition against DLD-1 human colon cancer cells using MTS assay
|
[PMID: 12036364]
|
DMS-79
|
IC50 |
|
Antiproliferative activity against human DMS79 cells after 72 hrs
Antiproliferative activity against human DMS79 cells after 72 hrs
|
[PMID: 17034133]
|
DU-145
|
GI50 |
0.00054 μM
Compound: 2, CA4
|
Cytotoxicity against human DU145 cells by SRB assay
Cytotoxicity against human DU145 cells by SRB assay
|
[PMID: 24016002]
|
DU-145
|
GI50 |
|
Growth inhibition of human DU145 cells by sulforhodamine B assay
Growth inhibition of human DU145 cells by sulforhodamine B assay
|
[PMID: 23772309]
|
DU-145
|
GI50 |
0.0008 μg/mL
Compound: CA4
|
Cytotoxicity against human DU145 cells after 48 hrs by SRB assay
Cytotoxicity against human DU145 cells after 48 hrs by SRB assay
|
[PMID: 18710804]
|
DU-145
|
GI50 |
0.0008 μg/mL
Compound: 1a, CA4
|
Growth inhibition of human DU145 cells after 48 hrs by sulforhodamine B assay
Growth inhibition of human DU145 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 22324723]
|
DU-145
|
GI50 |
0.0008 μg/mL
Compound: 2a
|
Growth inhibition of human DU145 cells after 48 hrs by sulforhodamine B assay
Growth inhibition of human DU145 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 19719153]
|
DU-145
|
GI50 |
0.0008 μg/mL
Compound: 1a, CA4
|
Cytotoxicity against human DU145 cells after 48 hrs by sulforhodamine B assay
Cytotoxicity against human DU145 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 16252907]
|
DU-145
|
GI50 |
0.0008 μg/mL
Compound: 3, CA4
|
Antitumor activity against human DU145 cells by sulforhodamine B assay
Antitumor activity against human DU145 cells by sulforhodamine B assay
|
[PMID: 19228038]
|
DU-145
|
GI50 |
0.0008 μM
Compound: CA4, combretastatin A4
|
Cytotoxicity against human DU145 cells after 48 hrs by SRB assay
Cytotoxicity against human DU145 cells after 48 hrs by SRB assay
|
[PMID: 18303849]
|
DU-145
|
GI50 |
0.001 μM
Compound: 2, combretastatin A-4, CA-4, NSC 613729
|
Growth inhibition of human DU145 cells after 48 hrs by SRB assay
Growth inhibition of human DU145 cells after 48 hrs by SRB assay
|
[PMID: 22982122]
|
DU-145
|
GI50 |
0.001 μM
Compound: 1, CA4
|
Cytotoxicity against human DU145 cells by SRB assay
Cytotoxicity against human DU145 cells by SRB assay
|
[PMID: 20496923]
|
DU-145
|
GI50 |
|
Growth inhibition of human DU145 after 48 hrs by SRB assay
Growth inhibition of human DU145 after 48 hrs by SRB assay
|
[PMID: 18722127]
|
DU-145
|
GI50 |
|
Cytotoxicity against human DU145 cells assessed as growth inhibition measured after 48 hrs by SRB assay
Cytotoxicity against human DU145 cells assessed as growth inhibition measured after 48 hrs by SRB assay
|
[PMID: 31059248]
|
DU-145
|
GI50 |
0.00327 μM
Compound: CA4, CA4P
|
Cytotoxicity against human DU145 cells after 48 hrs by SRB assay
Cytotoxicity against human DU145 cells after 48 hrs by SRB assay
|
[PMID: 24183586]
|
DU-145
|
GI50 |
|
Cytotoxicity against human DU145 cells after 48 hrs by SRB assay
Cytotoxicity against human DU145 cells after 48 hrs by SRB assay
|
[PMID: 23993969]
|
DU-145
|
GI50 |
|
Cytotoxicity against human DU145 cells assessed as reduction in cell viability incubated for 48 hrs by SRB assay
Cytotoxicity against human DU145 cells assessed as reduction in cell viability incubated for 48 hrs by SRB assay
|
[PMID: 31534659]
|
DU-145
|
IC50 |
0.007 μM
Compound: 1; CA-4
|
Cytotoxicity against human DU145 cells after 48 hrs by MTT assay
Cytotoxicity against human DU145 cells after 48 hrs by MTT assay
|
[PMID: 26970659]
|
DU-145
|
GI50 |
0.046 μM
Compound: 1; CA-4
|
Antiproliferative activity against human DU-145 cells assessed as cell growth inhibition measured after 48 hrs by SRB assay
Antiproliferative activity against human DU-145 cells assessed as cell growth inhibition measured after 48 hrs by SRB assay
|
[PMID: 27161282]
|
DU-145
|
IC50 |
0.069 μM
Compound: 2A; CA-4
|
Antiproliferative activity against human DU145 cells after 48 hrs by MTT assay
Antiproliferative activity against human DU145 cells after 48 hrs by MTT assay
|
[PMID: 28034647]
|
DU-145
|
GI50 |
|
Antiproliferative activity against human DU145 cells after 48 hrs by sulforhodamine B assay
Antiproliferative activity against human DU145 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 27515320]
|
DU-145
|
IC50 |
0.12 μM
Compound: 2a; CA-4
|
Cytotoxicity against human DU145 cells assessed as cell viability after 48 hrs by SRB assay
Cytotoxicity against human DU145 cells assessed as cell viability after 48 hrs by SRB assay
|
10.1039/C5MD00155B
|
DU-145
|
GI50 |
|
Antiproliferative activity against human DU145 cells after 48 hrs by MTT assay
Antiproliferative activity against human DU145 cells after 48 hrs by MTT assay
|
[PMID: 29227648]
|
DU-145
|
IC50 |
0.28 μM
Compound: CA-4; B
|
Antiproliferative activity against human DU145 cells after 48 hrs by MTT assay
Antiproliferative activity against human DU145 cells after 48 hrs by MTT assay
|
[PMID: 28774575]
|
DU-145
|
GI50 |
|
Anticancer activity against human DU145 cells after 24 hrs by SRB assay
Anticancer activity against human DU145 cells after 24 hrs by SRB assay
|
[PMID: 19733085]
|
DU-145
|
GI50 |
|
Cytotoxicity against human DU145 cells after 48 hrs by sulforhodamine B assay
Cytotoxicity against human DU145 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 21920767]
|
DU-145
|
IC50 |
32 nM
Compound: combretastatin A-4
|
Cell growth inhibition against DU-145 human prostate cancer cells using MTS assay
Cell growth inhibition against DU-145 human prostate cancer cells using MTS assay
|
[PMID: 12036364]
|
DU-145
|
IC50 |
|
Antiproliferative activity against human DU145 after 48 hrs by spectrophotometry
Antiproliferative activity against human DU145 after 48 hrs by spectrophotometry
|
[PMID: 21774499]
|
DU-145
|
IC50 |
|
Cytotoxicity against human DU145 cells after 72 hrs by MTT assay
Cytotoxicity against human DU145 cells after 72 hrs by MTT assay
|
[PMID: 17373779]
|
DU-145
|
GI50 |
|
Cytotoxicity against human DU145 cells assessed as growth inhibition after 48 hrs by SRB assay
Cytotoxicity against human DU145 cells assessed as growth inhibition after 48 hrs by SRB assay
|
[PMID: 26852340]
|
DU-145
|
GI50 |
8 x 10 -4 μg/mL
Compound: Z-1b
|
Cytotoxicity against human DU145 cells after 48 hrs by sulforhodamine B assay
Cytotoxicity against human DU145 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 19709889]
|
DU-145
|
IC50 |
|
Antiproliferative activity against human DU145 cells after 72 hrs
Antiproliferative activity against human DU145 cells after 72 hrs
|
[PMID: 17034133]
|
EA.hy 926
|
IC50 |
|
Cytotoxicity against human EA.hy 926 cells assessed as inhibition of cell growth after 72 hrs by MTT assay
Cytotoxicity against human EA.hy 926 cells assessed as inhibition of cell growth after 72 hrs by MTT assay
|
[PMID: 31958738]
|
EA.hy 926
|
IC50 |
|
Growth inhibition of human EAhy926 cells measured after 72 hrs by MTT assay
Growth inhibition of human EAhy926 cells measured after 72 hrs by MTT assay
|
[PMID: 27187864]
|
EA.hy 926
|
IC50 |
|
Growth inhibition of human EAhy926 cells after 72 hrs by MTT assay
Growth inhibition of human EAhy926 cells after 72 hrs by MTT assay
|
[PMID: 27116710]
|
ECa-109 cell line
|
IC50 |
|
Cytotoxicity against human ECA109 cells after 48 hrs by MTT assay
Cytotoxicity against human ECA109 cells after 48 hrs by MTT assay
|
[PMID: 19665898]
|
ECV-304
|
IC50 |
|
Cytotoxicity against human ECV304 cells after 72 hrs by MTT assay
Cytotoxicity against human ECV304 cells after 72 hrs by MTT assay
|
[PMID: 17373779]
|
EKVX
|
GI50 |
0.079 μM
Compound: 2, combretastatin A-4, CA-4, NSC 613729
|
Growth inhibition of human EKVX cells after 48 hrs by SRB assay
Growth inhibition of human EKVX cells after 48 hrs by SRB assay
|
[PMID: 22982122]
|
EKVX
|
GI50 |
0.086 μM
Compound: CA4, NSC 613729
|
Growth inhibition of human EKVX cells after 48 hrs by SRB assay
Growth inhibition of human EKVX cells after 48 hrs by SRB assay
|
[PMID: 24387982]
|
EKVX
|
GI50 |
|
Growth inhibition of human EKVX cells after 48 hrs by sulforhodamine B assay
Growth inhibition of human EKVX cells after 48 hrs by sulforhodamine B assay
|
[PMID: 24388833]
|
EMT6
|
IC50 |
|
Antiproliferative activity against drug resistant mouse EMT6/AR1 cells incubated for 24 hrs by sulforhodamine B assay
Antiproliferative activity against drug resistant mouse EMT6/AR1 cells incubated for 24 hrs by sulforhodamine B assay
|
[PMID: 26938120]
|
Epithelial cell
|
IC50 |
|
Cytotoxicity against in CD1 mouse mammary epithelial cells after 72 hrs by alamar blue dye assay
Cytotoxicity against in CD1 mouse mammary epithelial cells after 72 hrs by alamar blue dye assay
|
[PMID: 21080725]
|
FaDu
|
IC50 |
|
Antiproliferative activity against human CEM cells after 72 hrs
Antiproliferative activity against human CEM cells after 72 hrs
|
[PMID: 17034133]
|
FaDu
|
IC50 |
|
Antiproliferative activity against human FaDu cells assessed as cell growth inhibition incubated for 72 hrs by CCK-8 assay
Antiproliferative activity against human FaDu cells assessed as cell growth inhibition incubated for 72 hrs by CCK-8 assay
|
[PMID: 35576703]
|
Fibroblast
|
IC50 |
> 100 μM
Compound: 2, CA-4
|
Cytotoxicity against human fibroblast cells by alamar blue assay
Cytotoxicity against human fibroblast cells by alamar blue assay
|
[PMID: 22137934]
|
Fibroblast
|
IC50 |
|
Growth inhibition of primary chicken fibroblasts after 48 hrs by MTT assay
Growth inhibition of primary chicken fibroblasts after 48 hrs by MTT assay
|
[PMID: 27116710]
|
FM3A
|
IC50 |
0.042 μM
Compound: 1, CA-4
|
Antiproliferative activity against mouse FM3A cells after 2 days by coulter counter analysis
Antiproliferative activity against mouse FM3A cells after 2 days by coulter counter analysis
|
[PMID: 22027100]
|
FM3A
|
IC50 |
|
Antiproliferative activity against mouse FM3A cells after 2 days by Coulter counter method
Antiproliferative activity against mouse FM3A cells after 2 days by Coulter counter method
|
[PMID: 29220790]
|
FM3A
|
IC50 |
|
Antiproliferative activity against mouse FM3A cells after 2 days by coulter counting
Antiproliferative activity against mouse FM3A cells after 2 days by coulter counting
|
[PMID: 20579891]
|
FM3A
|
IC50 |
|
Antiproliferative activity against mouse FM3A cells after 2 days by coulter counter method
Antiproliferative activity against mouse FM3A cells after 2 days by coulter counter method
|
[PMID: 19663386]
|
FM3A
|
IC50 |
|
Cytotoxicity against mouse FM3A0 cells after 2 days
Cytotoxicity against mouse FM3A0 cells after 2 days
|
[PMID: 19736015]
|
FM3A
|
IC50 |
|
Antiproliferative activity against mouse FM3A cells after 2 days
Antiproliferative activity against mouse FM3A cells after 2 days
|
[PMID: 18755591]
|
FM3A
|
IC50 |
|
Antiproliferative effect against mouse FM3A cells after 2 days
Antiproliferative effect against mouse FM3A cells after 2 days
|
[PMID: 17419607]
|
H22
|
IC50 |
0.008 μM
Compound: CA-4; 1
|
Antiproliferative activity against human H22 cells after 72 hrs by MTT assay
Antiproliferative activity against human H22 cells after 72 hrs by MTT assay
|
[PMID: 30344902]
|
H22
|
IC50 |
0.015 μM
Compound: 1; CA-4
|
Antiproliferative activity against mouse H22 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
Antiproliferative activity against mouse H22 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
|
[PMID: 33676300]
|
H69AR
|
IC50 |
|
Antiproliferative activity against drug resistant H69AR cell line expressing MRP1 by Alamar Blue assay
Antiproliferative activity against drug resistant H69AR cell line expressing MRP1 by Alamar Blue assay
|
[PMID: 17286393]
|
HA22T cell line
|
IC50 |
2708 nM
Compound: combretastatin A-4
|
Cell growth inhibition against HA22T human liver cancer cells using MTS assay
Cell growth inhibition against HA22T human liver cancer cells using MTS assay
|
[PMID: 12036364]
|
HaCaT
|
IC50 |
|
Antiproliferative activity against human HaCaT cells after 72 hrs by SRB assay
Antiproliferative activity against human HaCaT cells after 72 hrs by SRB assay
|
[PMID: 30201525]
|
HaCaT
|
IC50 |
|
Antiproliferative activity against human HaCaT cells assessed as inhibition of cell proliferation measured after 48 hrs by SRB assay
Antiproliferative activity against human HaCaT cells assessed as inhibition of cell proliferation measured after 48 hrs by SRB assay
|
[PMID: 34837817]
|
HaCaT
|
IC50 |
|
Antiproliferative activity against human HaCaT cells measured after 72 hrs by MTT assay
Antiproliferative activity against human HaCaT cells measured after 72 hrs by MTT assay
|
[PMID: 27187864]
|
HaCaT
|
IC50 |
0.19 μM
Compound: 1a; CA-4
|
Cytotoxicity against human HaCaT cells after 48 hrs by MTT assay
Cytotoxicity against human HaCaT cells after 48 hrs by MTT assay
|
[PMID: 29291446]
|
HaCaT
|
IC50 |
|
Antiproliferative activity against human HaCaT cells assessed as cell viability by MTT assay
Antiproliferative activity against human HaCaT cells assessed as cell viability by MTT assay
|
[PMID: 23063401]
|
HBL-100
|
IC50 |
0.003 μM
Compound: 2, CA-4
|
Cytotoxicity against human HBL100 cells after 72 hrs by MTT assay
Cytotoxicity against human HBL100 cells after 72 hrs by MTT assay
|
[PMID: 18805012]
|
HBL-100
|
IC50 |
|
Cytotoxicity against human HBL100 cells after 72 hrs by MTT assay
Cytotoxicity against human HBL100 cells after 72 hrs by MTT assay
|
[PMID: 21488686]
|
HCC 2998
|
GI50 |
0.063 μM
Compound: CA4, NSC 613729
|
Growth inhibition of human HCC2998 cells after 48 hrs by SRB assay
Growth inhibition of human HCC2998 cells after 48 hrs by SRB assay
|
[PMID: 24387982]
|
HCC 2998
|
GI50 |
0.063 μM
Compound: 2, combretastatin A-4, CA-4, NSC 613729
|
Growth inhibition of human HCC2998 cells after 48 hrs by SRB assay
Growth inhibition of human HCC2998 cells after 48 hrs by SRB assay
|
[PMID: 22982122]
|
HCC 2998
|
GI50 |
0.063 μM
Compound: CA4; NSC 613729
|
Cytotoxicity against human HCC2998 cells by SRB assay
Cytotoxicity against human HCC2998 cells by SRB assay
|
[PMID: 26257861]
|
HCC 2998
|
GI50 |
|
Growth inhibition of human HCC2998 cells after 48 hrs by sulforhodamine B assay
Growth inhibition of human HCC2998 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 24388833]
|
HCT-116
|
IC50 |
|
Cytotoxicity against human HCT116 cells assessed as reduction of [3H]thymidine incorporation after 72 hrs by scintillation counting
Cytotoxicity against human HCT116 cells assessed as reduction of [3H]thymidine incorporation after 72 hrs by scintillation counting
|
[PMID: 21955454]
|
HCT-116
|
IC50 |
|
Antiproliferative activity against human HCT116 cells after 72 hrs by MTS assay
Antiproliferative activity against human HCT116 cells after 72 hrs by MTS assay
|
[PMID: 21112130]
|
HCT-116
|
IC50 |
|
Antiproliferative activity against human HCT116 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
Antiproliferative activity against human HCT116 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
|
[PMID: 31174062]
|
HCT-116
|
IC50 |
|
Cytotoxicity against human HCT116 cells after 72 hrs by MTT assay
Cytotoxicity against human HCT116 cells after 72 hrs by MTT assay
|
[PMID: 22676247]
|
HCT-116
|
IC50 |
|
Antiproliferative activity against human HCT116 cells assessed as reduction in cell viability by MTT assay
Antiproliferative activity against human HCT116 cells assessed as reduction in cell viability by MTT assay
|
[PMID: 31362922]
|
HCT-116
|
IC50 |
|
Antiproliferative activity against human HCT-116 cells assessed as reduction in cell viability incubated for 48 hrs by MTS assay
Antiproliferative activity against human HCT-116 cells assessed as reduction in cell viability incubated for 48 hrs by MTS assay
|
[PMID: 35635956]
|
HCT-116
|
IC50 |
|
Cytotoxicity against human HCT-116 p53 mutant cells assessed as inhibition of cell growth after 72 hrs by MTT assay
Cytotoxicity against human HCT-116 p53 mutant cells assessed as inhibition of cell growth after 72 hrs by MTT assay
|
[PMID: 31958738]
|
HCT-116
|
IC50 |
|
Cytotoxicity against human HCT116 cells after 72 hrs by MTS assay
Cytotoxicity against human HCT116 cells after 72 hrs by MTS assay
|
[PMID: 19211248]
|
HCT-116
|
IC50 |
|
Cytotoxicity against wild type human HCT-116 cells assessed as inhibition of cell growth after 72 hrs by MTT assay
Cytotoxicity against wild type human HCT-116 cells assessed as inhibition of cell growth after 72 hrs by MTT assay
|
[PMID: 31958738]
|
HCT-116
|
GI50 |
0.003 μM
Compound: CA4, NSC 613729
|
Growth inhibition of human HCT116 cells after 48 hrs by SRB assay
Growth inhibition of human HCT116 cells after 48 hrs by SRB assay
|
[PMID: 24387982]
|
HCT-116
|
GI50 |
0.003 μM
Compound: 2, combretastatin A-4, CA-4, NSC 613729
|
Growth inhibition of human HCT116 cells after 48 hrs by SRB assay
Growth inhibition of human HCT116 cells after 48 hrs by SRB assay
|
[PMID: 22982122]
|
HCT-116
|
GI50 |
0.003 μM
Compound: CA4; NSC 613729
|
Cytotoxicity against human HCT116 cells by SRB assay
Cytotoxicity against human HCT116 cells by SRB assay
|
[PMID: 26257861]
|
HCT-116
|
GI50 |
|
Growth inhibition of human HCT116 cells after 48 hrs by sulforhodamine B assay
Growth inhibition of human HCT116 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 27031215]
|
HCT-116
|
IC50 |
|
Antiproliferative activity against human HCT-116 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
Antiproliferative activity against human HCT-116 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
|
[PMID: 33581556]
|
HCT-116
|
IC50 |
|
Cytotoxicity against human HCT116 cells after 72 hrs by MTT assay
Cytotoxicity against human HCT116 cells after 72 hrs by MTT assay
|
[PMID: 25462279]
|
HCT-116
|
IC50 |
0.0047 μM
Compound: 6a; CA-4
|
Antiproliferative activity against human HCT-116 cells assessed as reduction in cell viability after 24 hrs by CCK-8 assay
Antiproliferative activity against human HCT-116 cells assessed as reduction in cell viability after 24 hrs by CCK-8 assay
|
[PMID: 34458740]
|
HCT-116
|
IC50 |
|
Antiproliferative activity against human HCT116 cells assessed as reduction in cell viability after 48 hrs by MTT assay
Antiproliferative activity against human HCT116 cells assessed as reduction in cell viability after 48 hrs by MTT assay
|
[PMID: 31185410]
|
HCT-116
|
GI50 |
|
Antiproliferative activity against human HCT-116 cells assessed as cell viability after 72 hrs by MTT assay
Antiproliferative activity against human HCT-116 cells assessed as cell viability after 72 hrs by MTT assay
|
[PMID: 31865012]
|
HCT-116
|
IC50 |
|
Cytotoxicity against human HCT116 cells assessed as growth inhibition after 72 hrs by MTT assay
Cytotoxicity against human HCT116 cells assessed as growth inhibition after 72 hrs by MTT assay
|
[PMID: 23708012]
|
HCT-116
|
IC50 |
|
Antiproliferative activity against human HCT116 cells by MTT assay
Antiproliferative activity against human HCT116 cells by MTT assay
|
[PMID: 29126741]
|
HCT-116
|
IC50 |
|
Anticancer activity against human HCT116 cells after 72 hrs
Anticancer activity against human HCT116 cells after 72 hrs
|
[PMID: 19713108]
|
HCT-116
|
IC50 |
0.008 μM
Compound: 1; CA-4
|
Antiproliferative activity against human HCT-116 cells after 48 hrs by MTT assay
Antiproliferative activity against human HCT-116 cells after 48 hrs by MTT assay
|
[PMID: 35065411]
|
HCT-116
|
IC50 |
|
Antiproliferative activity against human HCT-116 assessed as reduction in cell viability measured after 48 hrs by MTT assay
Antiproliferative activity against human HCT-116 assessed as reduction in cell viability measured after 48 hrs by MTT assay
|
[PMID: 34175541]
|
HCT-116
|
IC50 |
|
Antiproliferative activity against human HCT-116 cells assessed as inhibition of cell growth measured after 48 hrs by MTT assay
Antiproliferative activity against human HCT-116 cells assessed as inhibition of cell growth measured after 48 hrs by MTT assay
|
[PMID: 35834904]
|
HCT-116
|
IC50 |
0.01 μM
Compound: 2; CA-4
|
Antiproliferative activity against human HCT116 cells assessed as reduction in cell growth incubated for 72 hrs by MTT assay
Antiproliferative activity against human HCT116 cells assessed as reduction in cell growth incubated for 72 hrs by MTT assay
|
[PMID: 32912434]
|
HCT-116
|
IC50 |
0.029 μM
Compound: 1; CA-4
|
Antiproliferative activity against human HCT-116 cells assessed as reduction in cell growth incubated for 72 hrs by MTT assay
Antiproliferative activity against human HCT-116 cells assessed as reduction in cell growth incubated for 72 hrs by MTT assay
|
[PMID: 33421913]
|
HCT-116
|
IC50 |
0.0794 nM
Compound: 7; CA-4
|
Cytotoxicity against p53 deficient human HCT116 cells assessed as reduction in cell viability incubated for 72 hrs by MTS assay
Cytotoxicity against p53 deficient human HCT116 cells assessed as reduction in cell viability incubated for 72 hrs by MTS assay
|
[PMID: 31401010]
|
HCT-116
|
IC50 |
|
Antiproliferative activity against human HCT116 cells incubated for 48 hrs by MTT assay
Antiproliferative activity against human HCT116 cells incubated for 48 hrs by MTT assay
|
[PMID: 32035399]
|
HCT-116
|
IC50 |
|
Antiproliferative activity against human HCT116 cells incubated for 48 hrs by MTS assay
Antiproliferative activity against human HCT116 cells incubated for 48 hrs by MTS assay
|
[PMID: 31541870]
|
HCT-116
|
IC50 |
0.547 nM
Compound: 7; CA-4
|
Cytotoxicity against human HCT116 cells assessed as reduction in cell viability incubated for 72 hrs by MTS assay
Cytotoxicity against human HCT116 cells assessed as reduction in cell viability incubated for 72 hrs by MTS assay
|
[PMID: 31401010]
|
HCT-116
|
IC50 |
|
Antiproliferative activity against human HCT116 cells assessed as reduction in cell growth measured after 72 hrs by MTT assay
Antiproliferative activity against human HCT116 cells assessed as reduction in cell growth measured after 72 hrs by MTT assay
|
[PMID: 31830637]
|
HCT-116
|
IC50 |
|
Antiproliferative activity against human HCT-116 cells assessed as inhibition of cell growth by MTT assay
Antiproliferative activity against human HCT-116 cells assessed as inhibition of cell growth by MTT assay
|
[PMID: 35398303]
|
HCT-116
|
GI50 |
|
Cytotoxicity against human HCT116 cells assessed as growth inhibition after 48 hrs by SRB assay
Cytotoxicity against human HCT116 cells assessed as growth inhibition after 48 hrs by SRB assay
|
[PMID: 27707624]
|
HCT-116
|
GI50 |
|
Cytotoxicity against human HCT116 cells assessed as growth inhibition after 72 hrs by resazurin dye-based fluorimetric analysis
Cytotoxicity against human HCT116 cells assessed as growth inhibition after 72 hrs by resazurin dye-based fluorimetric analysis
|
[PMID: 24681982]
|
HCT-116
|
GI50 |
|
Growth inhibition of human HCT116 cells after 72 hrs by Victor microtiter plate fluorimeter analysis
Growth inhibition of human HCT116 cells after 72 hrs by Victor microtiter plate fluorimeter analysis
|
[PMID: 23353744]
|
HCT-116
|
GI50 |
|
Cytotoxicity against human HCT116 cells after 72 hrs using resazurin dye by microtiter plate fluorimeter analysis
Cytotoxicity against human HCT116 cells after 72 hrs using resazurin dye by microtiter plate fluorimeter analysis
|
[PMID: 22449653]
|
HCT-116
|
IC50 |
|
Cytotoxicity against human HCT116 cells after 72 hrs
Cytotoxicity against human HCT116 cells after 72 hrs
|
[PMID: 20627378]
|
HCT-116
|
GI50 |
|
Cytotoxicity against human HCT116 cells after 72 hrs by CellTitre-Blue assay
Cytotoxicity against human HCT116 cells after 72 hrs by CellTitre-Blue assay
|
[PMID: 25528337]
|
HCT-116
|
IC50 |
|
Antiproliferative activity against human HCT116 cells after 72 hrs by MTS assay
Antiproliferative activity against human HCT116 cells after 72 hrs by MTS assay
|
[PMID: 30525602]
|
HCT-116
|
IC50 |
|
Antiproliferative activity against human HCT116 cells after 72 hrs by resazurin-based fluorescence assay
Antiproliferative activity against human HCT116 cells after 72 hrs by resazurin-based fluorescence assay
|
[PMID: 29202409]
|
HCT-116
|
IC50 |
|
Cytotoxicity against human HCT116 cells after 72 hrs
Cytotoxicity against human HCT116 cells after 72 hrs
|
[PMID: 19530698]
|
HCT-116
|
GI50 |
|
Antiproliferative activity against human HCT-116 cells after 72 hrs by CellTiter Glo assay
Antiproliferative activity against human HCT-116 cells after 72 hrs by CellTiter Glo assay
|
[PMID: 35797900]
|
HCT-116
|
GI50 |
|
Antiproliferation activity against human HCT116 cells assessed as cell growth inhibition measured after 72 hrs by MTT assay
Antiproliferation activity against human HCT116 cells assessed as cell growth inhibition measured after 72 hrs by MTT assay
|
[PMID: 33201714]
|
HCT-116
|
IC50 |
|
Antiproliferative activity against human HCT116 cells assessed as cell viability after 24 hrs by Celltiter-Glo assay
Antiproliferative activity against human HCT116 cells assessed as cell viability after 24 hrs by Celltiter-Glo assay
|
[PMID: 33038796]
|
HCT-116
|
IC50 |
|
Growth inhibition of human HCT116 cells expressing wild type p53 after 72 hrs by MTT assay
Growth inhibition of human HCT116 cells expressing wild type p53 after 72 hrs by MTT assay
|
[PMID: 27116710]
|
HCT-116
|
IC50 |
|
Antiproliferative activity against human HCT116 cells after 72 hrs by MTT assay
Antiproliferative activity against human HCT116 cells after 72 hrs by MTT assay
|
[PMID: 31610375]
|
HCT-116
|
GI50 |
|
Growth inhibition of human HCT116 cells after 48 hrs by sulforhodamine B assay
Growth inhibition of human HCT116 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 24388833]
|
HCT-116
|
IC50 |
|
Growth inhibition of p53 null human HCT116 cells after 72 hrs by MTT assay
Growth inhibition of p53 null human HCT116 cells after 72 hrs by MTT assay
|
[PMID: 27116710]
|
HCT-116
|
IC50 |
|
Cytotoxicity against human HCT116 assessed as growth inhibition after 72 hrs by Celltiter-Glo luminescent assay
Cytotoxicity against human HCT116 assessed as growth inhibition after 72 hrs by Celltiter-Glo luminescent assay
|
[PMID: 23214452]
|
HCT-116
|
IC50 |
|
Antiproliferative activity against human HCT-116 cells assessed as inhibition of cell growth measured after 48 hrs by MTT assay
Antiproliferative activity against human HCT-116 cells assessed as inhibition of cell growth measured after 48 hrs by MTT assay
|
[PMID: 36334455]
|
HCT-116
|
IC50 |
|
Antiproliferative activity against human HCT-116 cells assessed as cell growth inhibition after 48 hrs by MTT assay
Antiproliferative activity against human HCT-116 cells assessed as cell growth inhibition after 48 hrs by MTT assay
|
[PMID: 33895499]
|
HCT-116
|
IC50 |
|
Cytotoxicity against human HCT116 cells assessed as inhibition of cell growth after 48 hrs by MTT assay
Cytotoxicity against human HCT116 cells assessed as inhibition of cell growth after 48 hrs by MTT assay
|
[PMID: 30448234]
|
HCT-116
|
IC50 |
|
Antiproliferative activity against human HCT116 cells after 48 hrs by MTT assay
Antiproliferative activity against human HCT116 cells after 48 hrs by MTT assay
|
[PMID: 28410492]
|
HCT-116
|
IC50 |
|
Cytotoxicity against human HCT116 cells assessed as growth inhibition after 48 hrs by MTT assay
Cytotoxicity against human HCT116 cells assessed as growth inhibition after 48 hrs by MTT assay
|
[PMID: 27810596]
|
HCT-116
|
IC50 |
|
Antiproliferative activity against human HCT-116 cells measured after 72 hrs by MTT assay
Antiproliferative activity against human HCT-116 cells measured after 72 hrs by MTT assay
|
[PMID: 36471625]
|
HCT-116
|
IC50 |
|
Antiproliferative activity against human HCT116 cells after 48 hrs by MTT assay
Antiproliferative activity against human HCT116 cells after 48 hrs by MTT assay
|
[PMID: 28792756]
|
HCT-116
|
IC50 |
|
Antiproliferative activity against human HCT116 cells after 72 hrs by CCK-8 assay
Antiproliferative activity against human HCT116 cells after 72 hrs by CCK-8 assay
|
[PMID: 30108925]
|
HCT-116
|
IC50 |
9.12 μM
Compound: CA-4; B
|
Antiproliferative activity against human HCT116 cells after 48 hrs by MTT assay
Antiproliferative activity against human HCT116 cells after 48 hrs by MTT assay
|
[PMID: 28774575]
|
HCT-15
|
GI50 |
< 0.01 μM
Compound: 1, CA-4
|
Growth inhibition of human HCT15 cells after 3 days by crystal violet staining
Growth inhibition of human HCT15 cells after 3 days by crystal violet staining
|
[PMID: 19954252]
|
HCT-15
|
IC50 |
|
Antiproliferative activity against human HCT15 cells after 72 hrs by MTS assay
Antiproliferative activity against human HCT15 cells after 72 hrs by MTS assay
|
[PMID: 21112130]
|
HCT-15
|
GI50 |
0.003 μM
Compound: 2, combretastatin A-4, CA-4, NSC 613729
|
Growth inhibition of human HCT15 cells after 48 hrs by SRB assay
Growth inhibition of human HCT15 cells after 48 hrs by SRB assay
|
[PMID: 22982122]
|
HCT-15
|
GI50 |
0.004 μM
Compound: CA4, NSC 613729
|
Growth inhibition of human HCT15 cells after 48 hrs by SRB assay
Growth inhibition of human HCT15 cells after 48 hrs by SRB assay
|
[PMID: 24387982]
|
HCT-15
|
GI50 |
0.004 μM
Compound: CA4; NSC 613729
|
Cytotoxicity against human HCT15 cells by SRB assay
Cytotoxicity against human HCT15 cells by SRB assay
|
[PMID: 26257861]
|
HCT-15
|
GI50 |
|
Growth inhibition of human HCT15 cells after 48 hrs by sulforhodamine B assay
Growth inhibition of human HCT15 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 27031215]
|
HCT-15
|
IC50 |
|
Antiproliferative activity against drug resistant HCT15 cell line expressing MDR1 by Alamar Blue assay
Antiproliferative activity against drug resistant HCT15 cell line expressing MDR1 by Alamar Blue assay
|
[PMID: 17286393]
|
HCT-15
|
IC50 |
|
Cytotoxicity against human HCT15 cells assessed as growth inhibition after 72 hrs by Celltiter-Glo luminescent assay
Cytotoxicity against human HCT15 cells assessed as growth inhibition after 72 hrs by Celltiter-Glo luminescent assay
|
[PMID: 23214452]
|
HCT-15
|
IC50 |
|
Antiproliferative activity against human HCT15 cells assessed as reduction in cell viability after 72 hrs by MTT assay
Antiproliferative activity against human HCT15 cells assessed as reduction in cell viability after 72 hrs by MTT assay
|
[PMID: 31610372]
|
HCT-15
|
GI50 |
|
Growth inhibition of human HCT15 cells after 48 hrs by sulforhodamine B assay
Growth inhibition of human HCT15 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 24388833]
|
HCT-15
|
IC50 |
|
Cytotoxicity against human HCT15 cells assessed as growth inhibition after 72 hrs by CellTitre-Glo assay
Cytotoxicity against human HCT15 cells assessed as growth inhibition after 72 hrs by CellTitre-Glo assay
|
[PMID: 25025991]
|
HCT-15
|
IC50 |
8.87 μM
Compound: CA-4; B
|
Antiproliferative activity against human HCT15 cells after 48 hrs by MTT assay
Antiproliferative activity against human HCT15 cells after 48 hrs by MTT assay
|
[PMID: 28774575]
|
HCT-8
|
IC50 |
|
Cytotoxicity against human HCT8 cells assessed as cell viability after 48 hrs by MTT assay
Cytotoxicity against human HCT8 cells assessed as cell viability after 48 hrs by MTT assay
|
[PMID: 27149641]
|
HCT-8
|
IC50 |
0.01 μM
Compound: 1; CA-4
|
Antiproliferative activity against human HCT8 cells assessed as reduction in cell viability after 72 hrs by MTT assay
Antiproliferative activity against human HCT8 cells assessed as reduction in cell viability after 72 hrs by MTT assay
|
[PMID: 30981112]
|
HCT-8
|
IC50 |
0.011 μM
Compound: 1; CA-4
|
Antiproliferative activity against human HCT-8 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
Antiproliferative activity against human HCT-8 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
|
[PMID: 33676300]
|
HCT-8
|
IC50 |
0.011 μM
Compound: 1; CA-4
|
Antiproliferative activity against human HCT8 cells after 72 hrs by MTT assay
Antiproliferative activity against human HCT8 cells after 72 hrs by MTT assay
|
[PMID: 30530194]
|
HCT-8
|
IC50 |
|
Antiproliferative activity against human HCT8 cells after 72 hrs by MTT assay
Antiproliferative activity against human HCT8 cells after 72 hrs by MTT assay
|
[PMID: 30525584]
|
HCT-8
|
IC50 |
0.015 μM
Compound: CA-4; 1
|
Antiproliferative activity against human HCT8 cells after 72 hrs by MTT assay
Antiproliferative activity against human HCT8 cells after 72 hrs by MTT assay
|
[PMID: 30344902]
|
HCT-8
|
IC50 |
|
Antiproliferative activity against human HCT-8 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
Antiproliferative activity against human HCT-8 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
|
[PMID: 34649064]
|
HCT-8
|
IC50 |
0.027 μM
Compound: 1; CA-4
|
Antiproliferative activity against human HCT8 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
Antiproliferative activity against human HCT8 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
|
[PMID: 32853870]
|
HCT-8
|
IC50 |
0.087 μM
Compound: 1; CA-4
|
Antiproliferative activity against taxol-resistant human HCT-8 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
Antiproliferative activity against taxol-resistant human HCT-8 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
|
[PMID: 33676300]
|
HEK293
|
IC50 |
|
Cytotoxicity against HEK293 cells after 68 hrs by MTT assay
Cytotoxicity against HEK293 cells after 68 hrs by MTT assay
|
[PMID: 32243160]
|
HEK293
|
IC50 |
1.73 μM
Compound: 1; CA-4
|
Antiproliferative activity against HEK293 cells after 24 hrs by SRB assay
Antiproliferative activity against HEK293 cells after 24 hrs by SRB assay
|
[PMID: 29268127]
|
HEK293
|
IC50 |
|
Cytotoxicity against HEK293 cells assessed as reduction in cell viability measured after 48 hrs by CCK8 assay
Cytotoxicity against HEK293 cells assessed as reduction in cell viability measured after 48 hrs by CCK8 assay
|
[PMID: 33280898]
|
HEK293
|
IC50 |
|
Cytotoxicity against HEK293 cells assessed as growth inhibition after 3 days by MTT assay
Cytotoxicity against HEK293 cells assessed as growth inhibition after 3 days by MTT assay
|
[PMID: 24145138]
|
HEK293
|
IC50 |
|
Cytotoxicity against HEK293 cells assessed as inhibition of cell growth after 72 hrs by MTT assay
Cytotoxicity against HEK293 cells assessed as inhibition of cell growth after 72 hrs by MTT assay
|
[PMID: 25240870]
|
HEK293
|
IC50 |
|
Antiproliferative activity against HEK293 cells by MTT assay
Antiproliferative activity against HEK293 cells by MTT assay
|
[PMID: 30502686]
|
HEK293
|
IC50 |
|
Antiproliferative activity against HEK293 cells after 2 days by MTT assay
Antiproliferative activity against HEK293 cells after 2 days by MTT assay
|
[PMID: 29432949]
|
HEK293
|
IC50 |
45.69 μM
Compound: 2; CA-4
|
Antiproliferative activity against HEK293 cells assessed as inhibition of cell growth measured after 48 hrs by MTT assay
Antiproliferative activity against HEK293 cells assessed as inhibition of cell growth measured after 48 hrs by MTT assay
|
[PMID: 36334455]
|
HEK293
|
IC50 |
|
Antiproliferative activity against human HEK293 cells assessed as cell growth inhibition after 48 hrs by MTT assay
Antiproliferative activity against human HEK293 cells assessed as cell growth inhibition after 48 hrs by MTT assay
|
[PMID: 33895499]
|
HEK293
|
IC50 |
|
Cytotoxicity against HEK293 cells assessed as reduction in cell growth after 48 hrs by MTT assay
Cytotoxicity against HEK293 cells assessed as reduction in cell growth after 48 hrs by MTT assay
|
[PMID: 33022479]
|
HEK293
|
IC50 |
|
Cytotoxicity against HEK293 cells measured after 48 hrs by MTT assay
Cytotoxicity against HEK293 cells measured after 48 hrs by MTT assay
|
[PMID: 32717486]
|
HEK293
|
IC50 |
45.69 μM
Compound: 1; CA-4
|
Cytotoxicity against HEK293 cells assessed as inhibition of cell growth by MTT assay
Cytotoxicity against HEK293 cells assessed as inhibition of cell growth by MTT assay
|
[PMID: 35398303]
|
HEK293
|
IC50 |
|
Cytotoxicity against human HEK293 cells after 72 hrs by MTT assay
Cytotoxicity against human HEK293 cells after 72 hrs by MTT assay
|
[PMID: 17373779]
|
HEK-293T
|
CC50 |
|
Cytotoxicity against HEK293T cells assessed as reduction in cell viability after 48 hrs by MTT assay
Cytotoxicity against HEK293T cells assessed as reduction in cell viability after 48 hrs by MTT assay
|
[PMID: 30041136]
|
HEK-293T
|
CC50 |
|
Antiproliferative activity against human HEK293T cells incubated for 48 hrs by MTT assay
Antiproliferative activity against human HEK293T cells incubated for 48 hrs by MTT assay
|
[PMID: 32035399]
|
HEK-293T
|
CC50 |
|
Cytotoxicity against HEK293T cells after 24 hrs by MTT assay
Cytotoxicity against HEK293T cells after 24 hrs by MTT assay
|
[PMID: 30606674]
|
HEK-293T
|
IC50 |
|
Inhibition of tubulin polymerization in HEK293T cell lysate after 15 mins by spectrophotometry
Inhibition of tubulin polymerization in HEK293T cell lysate after 15 mins by spectrophotometry
|
10.1039/C3MD00357D
|
HeLa
|
IC50 |
0.00051 μM
Compound: 1, CA4
|
Cytotoxicity against human HeLa cells by MTT assay
Cytotoxicity against human HeLa cells by MTT assay
|
[PMID: 19879758]
|
HeLa
|
IC50 |
|
Cytotoxicity against human HeLa cells after 72 hrs by resazurin based fluorescence assay
Cytotoxicity against human HeLa cells after 72 hrs by resazurin based fluorescence assay
|
[PMID: 24669888]
|
HeLa
|
IC50 |
|
Antiproliferative activity against human HeLa cells assessed as reduction in cell viability incubated for 48 hrs by MTS assay
Antiproliferative activity against human HeLa cells assessed as reduction in cell viability incubated for 48 hrs by MTS assay
|
[PMID: 35635956]
|
HeLa
|
IC50 |
0.002 μM
Compound: 1, CA-4
|
Antiproliferative activity against human HeLa cells after 2 days by coulter counter analysis
Antiproliferative activity against human HeLa cells after 2 days by coulter counter analysis
|
[PMID: 22027100]
|
HeLa
|
IC50 |
0.002 μM
Compound: CA-4, 1a
|
Cytotoxicity against human HeLa cells after 72 hrs by MTT assay
Cytotoxicity against human HeLa cells after 72 hrs by MTT assay
|
[PMID: 20338766]
|
HeLa
|
GI50 |
|
Antiproliferative activity against human HeLa cells after 48 hrs by MTT assay
Antiproliferative activity against human HeLa cells after 48 hrs by MTT assay
|
10.1039/C5MD00139K
|
HeLa
|
IC50 |
0.0029 μM
Compound: 6a; CA-4
|
Antiproliferative activity against human HeLa cells assessed as reduction in cell viability after 24 hrs by CCK-8 assay
Antiproliferative activity against human HeLa cells assessed as reduction in cell viability after 24 hrs by CCK-8 assay
|
[PMID: 34458740]
|
HeLa
|
IC50 |
0.0029 μM
Compound: 1, CA-4
|
Antiproliferative activity against human HeLa cells after 48 hrs by SRB assay
Antiproliferative activity against human HeLa cells after 48 hrs by SRB assay
|
[PMID: 19894742]
|
HeLa
|
IC50 |
0.003 μM
Compound: 1; CA4
|
Antiproliferative activity against human HeLa cells assessed as cell growth inhibition measured after 48 hrs by MTT assay
Antiproliferative activity against human HeLa cells assessed as cell growth inhibition measured after 48 hrs by MTT assay
|
[PMID: 32063430]
|
HeLa
|
IC50 |
|
Antiproliferative activity against human HeLa cells assessed as reduction in cell viability after 48 hrs by MTT assay
Antiproliferative activity against human HeLa cells assessed as reduction in cell viability after 48 hrs by MTT assay
|
[PMID: 31185410]
|
HeLa
|
IC50 |
|
Cytotoxicity against human HeLa cells after 72 hrs by MTT assay
Cytotoxicity against human HeLa cells after 72 hrs by MTT assay
|
[PMID: 25462279]
|
HeLa
|
IC50 |
|
Antiproliferative activity against human HeLa cells after 72 hrs by XTT assay
Antiproliferative activity against human HeLa cells after 72 hrs by XTT assay
|
[PMID: 30216850]
|
HeLa
|
IC50 |
0.003 μM
Compound: Combretastatin A-4
|
Cytotoxicity against human HeLa cells assessed as inhibition of cell proliferation after 72 hrs by XTT assay
Cytotoxicity against human HeLa cells assessed as inhibition of cell proliferation after 72 hrs by XTT assay
|
[PMID: 26092446]
|
HeLa
|
IC50 |
0.003 μM
Compound: II, CA-4
|
Cytotoxicity against human HeLa cells after 72 hrs by XTT assay
Cytotoxicity against human HeLa cells after 72 hrs by XTT assay
|
[PMID: 19939521]
|
HeLa
|
IC50 |
|
Cytotoxicity against human HeLa cells after 72 hrs by XTT assay
Cytotoxicity against human HeLa cells after 72 hrs by XTT assay
|
[PMID: 19647439]
|
HeLa
|
IC50 |
|
Cytotoxicity against human HeLa cells after 72 hrs by XTT method
Cytotoxicity against human HeLa cells after 72 hrs by XTT method
|
[PMID: 18502133]
|
HeLa
|
IC50 |
0.0033 μM
Compound: 1, CA-4
|
Antiproliferative activity against human HeLa cells expressing wild type beta3 tubulin after 48 hrs by SRB assay
Antiproliferative activity against human HeLa cells expressing wild type beta3 tubulin after 48 hrs by SRB assay
|
[PMID: 19894742]
|
HeLa
|
IC50 |
|
Antiproliferative activity against human HeLa assessed as reduction in cell viability measured after 48 hrs by MTT assay
Antiproliferative activity against human HeLa assessed as reduction in cell viability measured after 48 hrs by MTT assay
|
[PMID: 34175541]
|
HeLa
|
IC50 |
|
Antiproliferative activity against human HeLa cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
Antiproliferative activity against human HeLa cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
|
[PMID: 33581556]
|
HeLa
|
IC50 |
|
Cytotoxicity against human HeLa cells assessed as growth inhibition after 48 hrs by MTT assay
Cytotoxicity against human HeLa cells assessed as growth inhibition after 48 hrs by MTT assay
|
[PMID: 23809851]
|
HeLa
|
IC50 |
0.004 μM
Compound: CA-4;1a
|
Antiproliferative activity against human HeLa cells assessed as reduction in cell viability after 72 hrs by MTT assay
Antiproliferative activity against human HeLa cells assessed as reduction in cell viability after 72 hrs by MTT assay
|
[PMID: 33550186]
|
HeLa
|
IC50 |
|
Antiproliferative activity against human HeLa cells after 72 hrs by MTT assay
Antiproliferative activity against human HeLa cells after 72 hrs by MTT assay
|
[PMID: 30633509]
|
HeLa
|
IC50 |
0.0042 μM
Compound: 2; CA-4
|
Antiproliferation activity against human HeLa cells assessed as reduction in cell growth measured after 48 to 72 hrs by CCK-8 assay
Antiproliferation activity against human HeLa cells assessed as reduction in cell growth measured after 48 to 72 hrs by CCK-8 assay
|
[PMID: 35339837]
|
HeLa
|
IC50 |
0.0042 μM
Compound: 2; CA-4
|
Antiproliferative activity against human HeLa cells assessed as reduction in cell growth measured after 48 to 72 hrs by CCK-8 assay
Antiproliferative activity against human HeLa cells assessed as reduction in cell growth measured after 48 to 72 hrs by CCK-8 assay
|
[PMID: 35339837]
|
HeLa
|
IC50 |
|
Antiproliferative activity against human HeLa cells measured after 48 hrs by MTT assay
Antiproliferative activity against human HeLa cells measured after 48 hrs by MTT assay
|
[PMID: 32717486]
|
HeLa
|
IC50 |
|
Antiproliferative activity against human HeLa cells assessed as cell growth inhibition after 48 hrs by MTT assay
Antiproliferative activity against human HeLa cells assessed as cell growth inhibition after 48 hrs by MTT assay
|
[PMID: 33895499]
|
HeLa
|
IC50 |
|
Antiproliferative activity against human HeLa cells assessed as reduction in cell growth after 48 hrs by MTT assay
Antiproliferative activity against human HeLa cells assessed as reduction in cell growth after 48 hrs by MTT assay
|
[PMID: 33022479]
|
HeLa
|
IC50 |
0.005 μM
Compound: 2A; CA-4
|
Antiproliferative activity against human HeLa cells after 48 hrs by MTT assay
Antiproliferative activity against human HeLa cells after 48 hrs by MTT assay
|
[PMID: 28034647]
|
HeLa
|
IC50 |
0.005 μM
Compound: 1; CA-4
|
Antiproliferative activity against human HeLa cells assessed as reduction in cell growth incubated for 72 hrs by MTT assay
Antiproliferative activity against human HeLa cells assessed as reduction in cell growth incubated for 72 hrs by MTT assay
|
[PMID: 33421913]
|
HeLa
|
IC50 |
0.005 μM
Compound: 1; CA-4
|
Antiproliferative activity against human HeLa cells assessed as inhibition of cell growth by MTT assay
Antiproliferative activity against human HeLa cells assessed as inhibition of cell growth by MTT assay
|
[PMID: 35398303]
|
HeLa
|
IC50 |
|
Cytotoxicity against human HeLa cells assessed as reduction in cell viability measured after 24 hrs by MTT assay
Cytotoxicity against human HeLa cells assessed as reduction in cell viability measured after 24 hrs by MTT assay
|
[PMID: 35447432]
|
HeLa
|
IC50 |
|
Cytotoxicity against human HeLa cells assessed as inhibition of cell growth after 48 hrs by MTT assay
Cytotoxicity against human HeLa cells assessed as inhibition of cell growth after 48 hrs by MTT assay
|
[PMID: 30448234]
|
HeLa
|
IC50 |
0.007 μM
Compound: 2; CA-4
|
Antiproliferative activity against human HeLa cells assessed as reduction in cell growth incubated for 72 hrs by MTT assay
Antiproliferative activity against human HeLa cells assessed as reduction in cell growth incubated for 72 hrs by MTT assay
|
[PMID: 32912434]
|
HeLa
|
IC50 |
|
Antiproliferative activity against human HeLa cells by MTT assay
Antiproliferative activity against human HeLa cells by MTT assay
|
[PMID: 29126741]
|
HeLa
|
GI50 |
0.008 μM
Compound: 1; CA-4
|
Antiproliferative activity against human HeLa cells assessed as cell growth inhibition measured after 48 hrs by SRB assay
Antiproliferative activity against human HeLa cells assessed as cell growth inhibition measured after 48 hrs by SRB assay
|
[PMID: 27161282]
|
HeLa
|
IC50 |
0.009 μM
Compound: 8; CA-4
|
Antiproliferative activity against human HeLa cells assessed as cell growth inhibition after 72 hrs by SRB assay
Antiproliferative activity against human HeLa cells assessed as cell growth inhibition after 72 hrs by SRB assay
|
[PMID: 34454126]
|
HeLa
|
IC50 |
0.0093 μM
Compound: 3; CA-4
|
Growth inhibition of human HeLa cells incubated for 72 hrs by MTT assay
Growth inhibition of human HeLa cells incubated for 72 hrs by MTT assay
|
[PMID: 27172319]
|
HeLa
|
IC50 |
0.01 μM
Compound: 1; CA-4
|
Antiproliferative activity against human HeLa cells after 48 hrs by MTT assay
Antiproliferative activity against human HeLa cells after 48 hrs by MTT assay
|
[PMID: 29306206]
|
HeLa
|
IC50 |
|
Antiproliferative activity against human HeLa cells measured after 48 hrs by MTT assay
Antiproliferative activity against human HeLa cells measured after 48 hrs by MTT assay
|
[PMID: 27721152]
|
HeLa
|
IC50 |
|
Cytotoxicity against human HeLa cells assessed as cell viability after 48 hrs by MTT assay
Cytotoxicity against human HeLa cells assessed as cell viability after 48 hrs by MTT assay
|
[PMID: 27149641]
|
HeLa
|
IC50 |
|
Antiproliferative activity against human HeLa cells after 72 hrs by MTT assay
Antiproliferative activity against human HeLa cells after 72 hrs by MTT assay
|
[PMID: 29172084]
|
HeLa
|
IC50 |
|
Antiproliferative activity against human HeLa cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
Antiproliferative activity against human HeLa cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
|
[PMID: 34649064]
|
HeLa
|
IC50 |
|
Cytotoxicity against human HeLa cells after 48 hrs by MTT assay
Cytotoxicity against human HeLa cells after 48 hrs by MTT assay
|
[PMID: 25192811]
|
HeLa
|
IC50 |
|
Antiproliferative activity against human HeLa cells assessed as reduction in cell viability measured after 48 hrs by MTT assay
Antiproliferative activity against human HeLa cells assessed as reduction in cell viability measured after 48 hrs by MTT assay
|
[PMID: 34455231]
|
HeLa
|
IC50 |
|
Antiproliferative activity against human HeLa cells assessed as reduction in cell viability measured after 48 hrs by CCK8 assay
Antiproliferative activity against human HeLa cells assessed as reduction in cell viability measured after 48 hrs by CCK8 assay
|
[PMID: 33280898]
|
HeLa
|
GI50 |
|
Antiproliferative activity against human HeLa cells after 48 hrs by sulforhodamine B assay
Antiproliferative activity against human HeLa cells after 48 hrs by sulforhodamine B assay
|
[PMID: 27515320]
|
HeLa
|
GI50 |
0.084 μM
Compound: Combretastatin
|
Antiproliferative activity against human HeLa cells after 48 hrs by SRB cell proliferation assay
Antiproliferative activity against human HeLa cells after 48 hrs by SRB cell proliferation assay
|
[PMID: 29089233]
|
HeLa
|
GI50 |
|
Growth inhibition of human HeLa cells after 48 hrs by MTT assay
Growth inhibition of human HeLa cells after 48 hrs by MTT assay
|
[PMID: 30041136]
|
HeLa
|
IC50 |
0.11 μM
Compound: 1a; CA-4
|
Cytotoxicity against human HeLa cells after 48 hrs by MTT assay
Cytotoxicity against human HeLa cells after 48 hrs by MTT assay
|
[PMID: 29291446]
|
HeLa
|
IC50 |
0.15 μM
Compound: 2a; CA-4
|
Cytotoxicity against human HeLa cells assessed as cell viability after 48 hrs by SRB assay
Cytotoxicity against human HeLa cells assessed as cell viability after 48 hrs by SRB assay
|
10.1039/C5MD00155B
|
HeLa
|
IC50 |
|
Antiproliferative activity against human HeLa cells assessed as growth inhibition after 48 hrs by MTT assay
Antiproliferative activity against human HeLa cells assessed as growth inhibition after 48 hrs by MTT assay
|
[PMID: 22044164]
|
HeLa
|
IC50 |
|
Anticancer activity against human HeLa cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay
Anticancer activity against human HeLa cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay
|
[PMID: 31954880]
|
HeLa
|
IC50 |
|
Antiproliferative activity against human HeLa cells after 48 hrs by MTT assay
Antiproliferative activity against human HeLa cells after 48 hrs by MTT assay
|
[PMID: 28410492]
|
HeLa
|
IC50 |
|
Antiproliferative activity against human HeLa cells after 24 hrs by MTT assay
Antiproliferative activity against human HeLa cells after 24 hrs by MTT assay
|
[PMID: 30606674]
|
HeLa
|
CC50 |
|
Cytotoxicity against human HeLa cells assessed as reduction in cell viability measured after 72 hrs by cell titer blue assay
Cytotoxicity against human HeLa cells assessed as reduction in cell viability measured after 72 hrs by cell titer blue assay
|
[PMID: 31413794]
|
HeLa
|
IC50 |
|
Cytotoxicity against human HeLa cells assessed as reduction in cell viability incubated for 48 hrs by SRB assay
Cytotoxicity against human HeLa cells assessed as reduction in cell viability incubated for 48 hrs by SRB assay
|
[PMID: 28803799]
|
HeLa
|
IC50 |
|
Antiproliferative activity against human HeLa cells incubated for 48 hrs by MTS assay
Antiproliferative activity against human HeLa cells incubated for 48 hrs by MTS assay
|
[PMID: 31541870]
|
HeLa
|
EC50 |
1.4 nM
Compound: 5, (Z)-5, CA-4, Combretastatin A-4
|
Cytotoxicity against human HeLa cells assessed as cell viability after 48 hrs by MTS assay
Cytotoxicity against human HeLa cells assessed as cell viability after 48 hrs by MTS assay
|
10.1039/C0MD00095G
|
HeLa
|
IC50 |
1.43 μM
Compound: 1; CA-4
|
Antiproliferative activity against human HeLa cells after 24 hrs by SRB assay
Antiproliferative activity against human HeLa cells after 24 hrs by SRB assay
|
[PMID: 29268127]
|
HeLa
|
IC50 |
|
Antiproliferative activity against human HeLa cells after 24 to 48 hrs by CKK8 assay
Antiproliferative activity against human HeLa cells after 24 to 48 hrs by CKK8 assay
|
[PMID: 25105922]
|
HeLa
|
IC50 |
|
Cytotoxicity against human HeLa cells assessed as cell viability after 48 hrs by MTT assay
Cytotoxicity against human HeLa cells assessed as cell viability after 48 hrs by MTT assay
|
[PMID: 21696175]
|
HeLa
|
IC50 |
|
Growth inhibition of wild type human HeLa cells after 96 hrs incubation by sulforhodamine B technique
Growth inhibition of wild type human HeLa cells after 96 hrs incubation by sulforhodamine B technique
|
[PMID: 24900865]
|
HeLa
|
IC50 |
|
Growth inhibition of human HeLa cells measured after 96 hrs by sulforhodamine B assay
Growth inhibition of human HeLa cells measured after 96 hrs by sulforhodamine B assay
|
[PMID: 27894589]
|
HeLa
|
IC50 |
|
Antiproliferative activity against human HeLa cells after 2 days by coulter counting
Antiproliferative activity against human HeLa cells after 2 days by coulter counting
|
[PMID: 20579891]
|
HeLa
|
IC50 |
|
Antiproliferative activity against human HeLa cells after 2 days by coulter counter method
Antiproliferative activity against human HeLa cells after 2 days by coulter counter method
|
[PMID: 19663386]
|
HeLa
|
IC50 |
1.9 nM
Compound: 1a, CA-4
|
Cytotoxicity against human HeLa cells assessed as growth inhibition after 48 hrs by coulter counting analysis
Cytotoxicity against human HeLa cells assessed as growth inhibition after 48 hrs by coulter counting analysis
|
[PMID: 24164557]
|
HeLa
|
IC50 |
|
Cytotoxicity against human HeLa cells after 2 days
Cytotoxicity against human HeLa cells after 2 days
|
[PMID: 19736015]
|
HeLa
|
IC50 |
|
Antiproliferative activity against human HeLa cells assessed as reduction in cell viability measured after 48 hrs by MTT assay
Antiproliferative activity against human HeLa cells assessed as reduction in cell viability measured after 48 hrs by MTT assay
|
[PMID: 32339854]
|
HeLa
|
IC50 |
|
Antiproliferative activity against human HeLa cells after 72 hrs by CCK-8 assay
Antiproliferative activity against human HeLa cells after 72 hrs by CCK-8 assay
|
[PMID: 30108925]
|
HeLa
|
IC50 |
|
Antiproliferative activity against human HeLa cells after 72 hrs by CCK8 assay
Antiproliferative activity against human HeLa cells after 72 hrs by CCK8 assay
|
[PMID: 30006162]
|
HeLa
|
IC50 |
|
Cytotoxicity against human HeLa cells after 48 hrs by MTT assay
Cytotoxicity against human HeLa cells after 48 hrs by MTT assay
|
10.1039/C3MD00372H
|
HeLa
|
IC50 |
|
Antiproliferative activity against human HeLa cells after 4 days by Coulter counter method
Antiproliferative activity against human HeLa cells after 4 days by Coulter counter method
|
[PMID: 29220790]
|
HeLa
|
IC50 |
|
Cytotoxicity against human HeLa cells after 48 hrs by MTT assay
Cytotoxicity against human HeLa cells after 48 hrs by MTT assay
|
[PMID: 23356786]
|
HeLa
|
IC50 |
|
Antiproliferative activity against human HeLa cells by MTT assay
Antiproliferative activity against human HeLa cells by MTT assay
|
[PMID: 30502686]
|
HeLa
|
IC50 |
|
Cytotoxicity against human HeLa cells after 48 hrs by WST-8 assay
Cytotoxicity against human HeLa cells after 48 hrs by WST-8 assay
|
[PMID: 22727370]
|
HeLa
|
IC50 |
|
Growth inhibition of human HeLa cells overexpressing beta-3 after 96 hrs incubation by sulforhodamine B technique
Growth inhibition of human HeLa cells overexpressing beta-3 after 96 hrs incubation by sulforhodamine B technique
|
[PMID: 24900865]
|
HeLa
|
IC50 |
|
Growth inhibition of human HeLa cells over expressing beta3-tubulin measured after 96 hrs by sulforhodamine B assay
Growth inhibition of human HeLa cells over expressing beta3-tubulin measured after 96 hrs by sulforhodamine B assay
|
[PMID: 27894589]
|
HeLa
|
IC50 |
|
Cytotoxicity against human HeLa cells after 72 hrs by XTT assay
Cytotoxicity against human HeLa cells after 72 hrs by XTT assay
|
[PMID: 18790642]
|
HeLa
|
IC50 |
2.78 μM
Compound: Combretastatin A-4
|
Antiproliferative activity against human HeLa cells incubated for 24 hrs by MTT assay
Antiproliferative activity against human HeLa cells incubated for 24 hrs by MTT assay
|
[PMID: 32992133]
|
HeLa
|
IC50 |
|
Cytotoxicity against human HeLa cells assessed as growth inhibition after 48 hrs by MTT assay
Cytotoxicity against human HeLa cells assessed as growth inhibition after 48 hrs by MTT assay
|
[PMID: 23214452]
|
HeLa
|
IC50 |
|
Antiproliferative activity against human HeLa cells after 2 days by MTT assay
Antiproliferative activity against human HeLa cells after 2 days by MTT assay
|
[PMID: 29432949]
|
HeLa
|
IC50 |
|
Antiproliferative activity against human HeLa cells incubated for 24 hrs by sulforhodamine B assay
Antiproliferative activity against human HeLa cells incubated for 24 hrs by sulforhodamine B assay
|
[PMID: 26938120]
|
HeLa
|
IC50 |
|
Antiproliferative activity against human HeLa cells assessed as inhibition of cell growth after 72 hrs by XTT assay
Antiproliferative activity against human HeLa cells assessed as inhibition of cell growth after 72 hrs by XTT assay
|
[PMID: 33328100]
|
HeLa
|
IC50 |
|
Antiproliferative activity against human HeLa cells after 48 hrs by SRB assay
Antiproliferative activity against human HeLa cells after 48 hrs by SRB assay
|
[PMID: 27213719]
|
HeLa
|
IC50 |
|
Antiproliferative activity against multidrug resistant human HeLa cells expressing wild type beta3 tubulin after 48 hrs by SRB assay
Antiproliferative activity against multidrug resistant human HeLa cells expressing wild type beta3 tubulin after 48 hrs by SRB assay
|
[PMID: 27213719]
|
HeLa
|
IC50 |
|
Antiproliferative activity against human HeLa cells overexpressing betaIII-tubulin assessed as inhibition of cell growth by SRB assay
Antiproliferative activity against human HeLa cells overexpressing betaIII-tubulin assessed as inhibition of cell growth by SRB assay
|
[PMID: 36889150]
|
HeLa
|
IC50 |
|
Antiproliferative activity against wild type human HeLa cells assessed as inhibition of cell growth by SRB assay
Antiproliferative activity against wild type human HeLa cells assessed as inhibition of cell growth by SRB assay
|
[PMID: 36889150]
|
HeLa
|
IC50 |
|
Antiproliferative activity against human HeLa cells after 48 hrs by sulforhodamine B assay
Antiproliferative activity against human HeLa cells after 48 hrs by sulforhodamine B assay
|
[PMID: 30297118]
|
HeLa
|
IC50 |
|
Antiproliferative activity against human HeLa cells expressing wild type beta3 tubulin after 48 hrs by sulforhodamine B assay
Antiproliferative activity against human HeLa cells expressing wild type beta3 tubulin after 48 hrs by sulforhodamine B assay
|
[PMID: 30297118]
|
HeLa
|
IC50 |
|
Antiproliferative activity against human HeLa cells after 72 hrs by sulforhodamine B assay
Antiproliferative activity against human HeLa cells after 72 hrs by sulforhodamine B assay
|
[PMID: 30098869]
|
HeLa
|
IC50 |
|
Cytotoxicity against human HeLa cells assessed as reduction in cell viability by Sulforhodamine B assay
Cytotoxicity against human HeLa cells assessed as reduction in cell viability by Sulforhodamine B assay
|
[PMID: 33647840]
|
HeLa
|
IC50 |
|
Cytotoxicity against human HeLa cells over expressing WT-beta3 assessed as reduction in cell viability by Sulforhodamine B assay
Cytotoxicity against human HeLa cells over expressing WT-beta3 assessed as reduction in cell viability by Sulforhodamine B assay
|
[PMID: 33647840]
|
HeLa
|
IC50 |
|
Antiproliferative activity against human HeLa cells after 48 hrs by MTT assay
Antiproliferative activity against human HeLa cells after 48 hrs by MTT assay
|
[PMID: 28792756]
|
HeLa
|
IC50 |
|
Cytotoxicity against human HeLa cells expressing beta3-tubulin containing alanine residue at 227 after 72 hrs by MTS assay
Cytotoxicity against human HeLa cells expressing beta3-tubulin containing alanine residue at 227 after 72 hrs by MTS assay
|
[PMID: 24087857]
|
HeLa
|
IC50 |
|
Antiproliferative activity against human HeLa cells assessed as inhibition of cell proliferation incubated for 72 hrs by MTT assay
Antiproliferative activity against human HeLa cells assessed as inhibition of cell proliferation incubated for 72 hrs by MTT assay
|
[PMID: 31400707]
|
HeLa
|
IC50 |
|
Growth inhibition of human HeLa cells after 72 hrs by MTT assay
Growth inhibition of human HeLa cells after 72 hrs by MTT assay
|
[PMID: 25025853]
|
HeLa
|
IC50 |
|
Cytotoxicity against human HeLa cells after 72 hrs by MTT assay
Cytotoxicity against human HeLa cells after 72 hrs by MTT assay
|
[PMID: 23445496]
|
HeLa
|
IC50 |
4 nM
Compound: CA-4, 1a, 1
|
Antiproliferative activity against human HeLa cells after 72 hrs by MTT assay
Antiproliferative activity against human HeLa cells after 72 hrs by MTT assay
|
[PMID: 23117171]
|
HeLa
|
IC50 |
|
Antiproliferative activity against human HeLa cells assessed as growth inhibition after 72 hrs by MTT assay
Antiproliferative activity against human HeLa cells assessed as growth inhibition after 72 hrs by MTT assay
|
[PMID: 22578111]
|
HeLa
|
IC50 |
|
Cytotoxicity against human HeLa cells after 72 hrs by MTT assay
Cytotoxicity against human HeLa cells after 72 hrs by MTT assay
|
[PMID: 22136312]
|
HeLa
|
IC50 |
|
Antiproliferative activity against human HeLa cells assessed as growth inhibition after 72 hrs by MTT assay
Antiproliferative activity against human HeLa cells assessed as growth inhibition after 72 hrs by MTT assay
|
[PMID: 21663319]
|
HeLa
|
IC50 |
|
Antiproliferative activity against human HeLa cells after 72 hrs by MTT assay
Antiproliferative activity against human HeLa cells after 72 hrs by MTT assay
|
[PMID: 20420439]
|
HeLa
|
IC50 |
|
Antiproliferative activity against human HeLa cells after 72 hrs by (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide test
Antiproliferative activity against human HeLa cells after 72 hrs by (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide test
|
[PMID: 25785605]
|
HeLa
|
IC50 |
|
Cytotoxicity against human HeLa cells after 72 hrs by MTS assay
Cytotoxicity against human HeLa cells after 72 hrs by MTS assay
|
[PMID: 24087857]
|
HeLa
|
IC50 |
|
Antiproliferative activity against human HeLa cells assessed as cell growth inhibition by MTT assay
Antiproliferative activity against human HeLa cells assessed as cell growth inhibition by MTT assay
|
[PMID: 33636303]
|
HeLa
|
IC50 |
|
Antiproliferative activity against human HeLa cells assessed as decrease in cell growth measured after 48 hrs by SRB method
Antiproliferative activity against human HeLa cells assessed as decrease in cell growth measured after 48 hrs by SRB method
|
[PMID: 33310545]
|
HeLa
|
IC50 |
|
Antiproliferative activity against human HeLa cells after 48 hrs by SRB assay
Antiproliferative activity against human HeLa cells after 48 hrs by SRB assay
|
[PMID: 23895532]
|
HeLa
|
IC50 |
|
Cytotoxicity against human HeLa cells assessed as growth inhibition after 48 hrs by SRB assay
Cytotoxicity against human HeLa cells assessed as growth inhibition after 48 hrs by SRB assay
|
[PMID: 23332369]
|
HeLa
|
IC50 |
|
Antiproliferative activity against human HeLa cells by SRB assay
Antiproliferative activity against human HeLa cells by SRB assay
|
[PMID: 29655610]
|
HeLa
|
IC50 |
|
Antiproliferative activity against human HeLa cells assessed as inhibition of cell growth measured after 48 hrs by MTT assay
Antiproliferative activity against human HeLa cells assessed as inhibition of cell growth measured after 48 hrs by MTT assay
|
[PMID: 36334455]
|
HeLa
|
IC50 |
|
Inhibition of beta-3 tubulin (unknown origin) transfected in human HeLa cells assessed as growth inhibition after 48 hrs by SRB assay
Inhibition of beta-3 tubulin (unknown origin) transfected in human HeLa cells assessed as growth inhibition after 48 hrs by SRB assay
|
[PMID: 23332369]
|
HeLa
|
IC50 |
5.36 μM
Compound: Combretastatin
|
Antiproliferative activity in human HeLa cells assessed as reduction in cell number incubated for 48 hrs by SRB assay
Antiproliferative activity in human HeLa cells assessed as reduction in cell number incubated for 48 hrs by SRB assay
|
[PMID: 30108756]
|
HeLa
|
IC50 |
|
Antiproliferative activity against human HeLa cells after 48 hrs by sulforhodamine B assay
Antiproliferative activity against human HeLa cells after 48 hrs by sulforhodamine B assay
|
[PMID: 25882519]
|
HeLa
|
IC50 |
|
Inhibition of beta3 tubulin overexpressed in human HeLa cells after 48 hrs by SRB assay
Inhibition of beta3 tubulin overexpressed in human HeLa cells after 48 hrs by SRB assay
|
[PMID: 23895532]
|
HeLa
|
IC50 |
|
Antiproliferative activity against human HeLa cells expressing wild type beta3 tubulin by SRB assay
Antiproliferative activity against human HeLa cells expressing wild type beta3 tubulin by SRB assay
|
[PMID: 29655610]
|
HeLa
|
IC50 |
|
Antiproliferative activity against human HeLa cells overexpressing wild type beta3 tubulin after 48 hrs by sulforhodamine B assay
Antiproliferative activity against human HeLa cells overexpressing wild type beta3 tubulin after 48 hrs by sulforhodamine B assay
|
[PMID: 25882519]
|
HeLa
|
IC50 |
|
Antiproliferative activity against human HeLa cells after 48 hrs by sulforhodamine B assay
Antiproliferative activity against human HeLa cells after 48 hrs by sulforhodamine B assay
|
[PMID: 28684120]
|
HeLa
|
EC50 |
|
Inhibition of Tubulin polymerization in human HeLa cells assessed as decrease in dynamic tyrosinated microtubules after 2 hrs by microplate reader analysis
Inhibition of Tubulin polymerization in human HeLa cells assessed as decrease in dynamic tyrosinated microtubules after 2 hrs by microplate reader analysis
|
[PMID: 26602281]
|
HeLa
|
IC50 |
|
Antiproliferative activity against human HeLa cells assessed as reduction in cell viability after 72 hrs by MTT assay
Antiproliferative activity against human HeLa cells assessed as reduction in cell viability after 72 hrs by MTT assay
|
[PMID: 31610372]
|
HEp-2
|
IC50 |
0.0052 μM
Compound: CA-4, 1a
|
Cytotoxicity against human cisplatin-resistant Hep2 cells after 72 hrs by MTT assay
Cytotoxicity against human cisplatin-resistant Hep2 cells after 72 hrs by MTT assay
|
[PMID: 20338766]
|
HEp-2
|
IC50 |
0.0055 μM
Compound: CA-4, 1a
|
Cytotoxicity against human Hep2 cells after 72 hrs by MTT assay
Cytotoxicity against human Hep2 cells after 72 hrs by MTT assay
|
[PMID: 20338766]
|
HEp-2
|
IC50 |
|
Cytotoxicity against human Hep2 cells after 72 hrs by MTT assay
Cytotoxicity against human Hep2 cells after 72 hrs by MTT assay
|
[PMID: 17373779]
|
Hepatocyte
|
CC50 |
|
Cytotoxicity against mouse primary hepatocytes after 24 hrs by MTT assay
Cytotoxicity against mouse primary hepatocytes after 24 hrs by MTT assay
|
[PMID: 30606674]
|
HepG2
|
EC50 |
|
Cell cycle arrest in human HepG2 cells assessed as increase in G2/M phase cells after 20 hrs by flow cytometry using propidium iodide staining
Cell cycle arrest in human HepG2 cells assessed as increase in G2/M phase cells after 20 hrs by flow cytometry using propidium iodide staining
|
[PMID: 19713108]
|
HepG2
|
GI50 |
|
Antiproliferative activity against human HepG2 cells assessed as cell viability after 72 hrs by MTT assay
Antiproliferative activity against human HepG2 cells assessed as cell viability after 72 hrs by MTT assay
|
[PMID: 31865012]
|
HepG2
|
IC50 |
|
Antiproliferative activity against human HepG2 cells measured after 48 hrs by SRB assay
Antiproliferative activity against human HepG2 cells measured after 48 hrs by SRB assay
|
[PMID: 32113125]
|
HepG2
|
IC50 |
0.002 μM
Compound: 1; CA-4
|
Antiproliferative activity against human HepG2 assessed as reduction in cell viability measured after 48 hrs by SRB assay
Antiproliferative activity against human HepG2 assessed as reduction in cell viability measured after 48 hrs by SRB assay
|
[PMID: 27919655]
|
HepG2
|
IC50 |
0.0021 μM
Compound: 3; CA-4
|
Growth inhibition of human HepG2 cells incubated for 72 hrs by MTT assay
Growth inhibition of human HepG2 cells incubated for 72 hrs by MTT assay
|
[PMID: 27172319]
|
HepG2
|
IC50 |
0.0029 μM
Compound: 6a; CA-4
|
Antiproliferative activity against human HepG2 cells assessed as reduction in cell viability after 24 hrs by CCK-8 assay
Antiproliferative activity against human HepG2 cells assessed as reduction in cell viability after 24 hrs by CCK-8 assay
|
[PMID: 34458740]
|
HepG2
|
IC50 |
0.006 μM
Compound: 2; CA-4
|
Antiproliferative activity against human HepG2 cells assessed as reduction in cell growth incubated for 72 hrs by MTT assay
Antiproliferative activity against human HepG2 cells assessed as reduction in cell growth incubated for 72 hrs by MTT assay
|
[PMID: 32912434]
|
HepG2
|
IC50 |
|
Cytotoxicity against human HepG2 cells assessed as growth inhibition after 72 hrs by MTT assay
Cytotoxicity against human HepG2 cells assessed as growth inhibition after 72 hrs by MTT assay
|
[PMID: 23708012]
|
HepG2
|
IC50 |
|
Anticancer activity against human HepG2 cells after 72 hrs
Anticancer activity against human HepG2 cells after 72 hrs
|
[PMID: 19713108]
|
HepG2
|
IC50 |
0.007 μM
Compound: 8; CA-4
|
Antiproliferative activity against human HepG2 cells assessed as cell growth inhibition after 72 hrs by SRB assay
Antiproliferative activity against human HepG2 cells assessed as cell growth inhibition after 72 hrs by SRB assay
|
[PMID: 34454126]
|
HepG2
|
IC50 |
|
Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay
Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay
|
[PMID: 25192811]
|
HepG2
|
IC50 |
|
Growth inhibition of human HepG2 cells after 48 hrs by MTT assay
Growth inhibition of human HepG2 cells after 48 hrs by MTT assay
|
[PMID: 29509413]
|
HepG2
|
IC50 |
0.009 μM
Compound: 2A; CA-4
|
Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay
Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay
|
[PMID: 28034647]
|
HepG2
|
IC50 |
0.009 μM
Compound: 1; CA-4
|
Antiproliferative activity against human HepG2 cells after 72 hrs by MTT assay
Antiproliferative activity against human HepG2 cells after 72 hrs by MTT assay
|
[PMID: 30530194]
|
HepG2
|
IC50 |
|
Cytotoxicity against human HepG2 cells assessed as reduction in cell viability by MTT assay
Cytotoxicity against human HepG2 cells assessed as reduction in cell viability by MTT assay
|
[PMID: 33010448]
|
HepG2
|
IC50 |
|
Antiproliferative activity against human HepG2 cells assessed as reduction in cell viability measured after 48 hrs by MTT assay
Antiproliferative activity against human HepG2 cells assessed as reduction in cell viability measured after 48 hrs by MTT assay
|
[PMID: 34455231]
|
HepG2
|
IC50 |
0.01 μM
Compound: 1; CA-4
|
Antiproliferative activity against human HepG2 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
Antiproliferative activity against human HepG2 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
|
[PMID: 33676300]
|
HepG2
|
IC50 |
0.012 μM
Compound: 1; CA-4
|
Antiproliferative activity against human HepG2 cells assessed as reduction in cell viability after 72 hrs by MTT assay
Antiproliferative activity against human HepG2 cells assessed as reduction in cell viability after 72 hrs by MTT assay
|
[PMID: 30981112]
|
HepG2
|
IC50 |
|
Antiproliferative activity against human HepG2 cells after 72 hrs by MTT assay
Antiproliferative activity against human HepG2 cells after 72 hrs by MTT assay
|
[PMID: 30525584]
|
HepG2
|
IC50 |
0.012 μM
Compound: CA-4; 2
|
Antiproliferative activity against human HepG2 cells after 72 hrs by MTT assay
Antiproliferative activity against human HepG2 cells after 72 hrs by MTT assay
|
[PMID: 30176537]
|
HepG2
|
IC50 |
0.023 μM
Compound: 1; CA-4
|
Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay
Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay
|
[PMID: 26970659]
|
HepG2
|
IC50 |
0.031 μM
Compound: 1; CA-4
|
Antiproliferative activity against human HepG2 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
Antiproliferative activity against human HepG2 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
|
[PMID: 32853870]
|
HepG2
|
GI50 |
|
Antiproliferative activity against human HepG2 cells after 48 hrs by sulforhodamine B assay
Antiproliferative activity against human HepG2 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 27515320]
|
HepG2
|
IC50 |
|
Antiproliferative activity against human HepG2 cells measured after 48 hrs by MTT assay
Antiproliferative activity against human HepG2 cells measured after 48 hrs by MTT assay
|
[PMID: 35551039]
|
HepG2
|
IC50 |
|
Growth inhibition of human HepG2 cells measured after 72 hrs by MTT assay
Growth inhibition of human HepG2 cells measured after 72 hrs by MTT assay
|
[PMID: 27187864]
|
HepG2
|
IC50 |
|
Antiproliferative activity against mouse HepG2 cells after 48 hrs by MTT assay
Antiproliferative activity against mouse HepG2 cells after 48 hrs by MTT assay
|
[PMID: 24909678]
|
HepG2
|
IC50 |
|
Antiproliferative activity against human HepG2 cells assessed as reduction in cell viability after 24 hrs by MTT assay
Antiproliferative activity against human HepG2 cells assessed as reduction in cell viability after 24 hrs by MTT assay
|
[PMID: 25828827]
|
HepG2
|
GI50 |
|
Growth inhibition of human HepG2 cells after 48 hrs by MTT assay
Growth inhibition of human HepG2 cells after 48 hrs by MTT assay
|
[PMID: 30041136]
|
HepG2
|
IC50 |
0.19 μg/mL
Compound: 1, CA-4
|
Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay
Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay
|
[PMID: 21440448]
|
HepG2
|
IC50 |
|
Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay
Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay
|
[PMID: 22512906]
|
HepG2
|
IC50 |
|
Antiproliferative activity against human HepG2 cells after 72 hrs by MTT assay
Antiproliferative activity against human HepG2 cells after 72 hrs by MTT assay
|
[PMID: 29396364]
|
HepG2
|
IC50 |
|
Antiproliferative activity against human HepG2 cells incubated for 48 hrs by MTT assay
Antiproliferative activity against human HepG2 cells incubated for 48 hrs by MTT assay
|
[PMID: 32035399]
|
HepG2
|
IC50 |
0.28 μM
Compound: 1; CA-4
|
Antiproliferative activity against human HepG2 cells assessed as reduction in cell growth incubated for 72 hrs by MTT assay
Antiproliferative activity against human HepG2 cells assessed as reduction in cell growth incubated for 72 hrs by MTT assay
|
[PMID: 33421913]
|
HepG2
|
IC50 |
|
Antiproliferative activity against human HepG2 cells after 24 hrs by MTT assay
Antiproliferative activity against human HepG2 cells after 24 hrs by MTT assay
|
[PMID: 30606674]
|
HepG2
|
IC50 |
|
Antiproliferative activity against human HepG2 cells assessed as reduction in cell growth measured after 72 hrs by MTT assay
Antiproliferative activity against human HepG2 cells assessed as reduction in cell growth measured after 72 hrs by MTT assay
|
[PMID: 31830637]
|
HepG2
|
IC50 |
|
Antiproliferative activity against human HepG2 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
Antiproliferative activity against human HepG2 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
|
[PMID: 36252396]
|
HepG2
|
IC50 |
0.54 μg/mL
Compound: CA-4
|
Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay
Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay
|
[PMID: 22192936]
|
HepG2
|
IC50 |
|
Antiproliferative activity against human HepG2 cells assessed as reduction in cell viability measured after 48 hrs by CCK8 assay
Antiproliferative activity against human HepG2 cells assessed as reduction in cell viability measured after 48 hrs by CCK8 assay
|
[PMID: 33280898]
|
HepG2
|
IC50 |
|
Antiproliferative activity against human HepG2 cells after 72 hrs by CCK-8 assay
Antiproliferative activity against human HepG2 cells after 72 hrs by CCK-8 assay
|
[PMID: 30108925]
|
HepG2
|
IC50 |
|
Cytotoxicity against human HepG2 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay
Cytotoxicity against human HepG2 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay
|
[PMID: 35964428]
|
HepG2
|
IC50 |
|
Antiproliferative activity against human HepG2 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay
Antiproliferative activity against human HepG2 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay
|
[PMID: 31536891]
|
HepG2
|
IC50 |
|
Cytotoxicity in human HepG2 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
Cytotoxicity in human HepG2 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
|
[PMID: 29031074]
|
HepG2
|
IC50 |
|
Antiproliferative activity against human HepG2 cells after 72 hrs by MTT assay
Antiproliferative activity against human HepG2 cells after 72 hrs by MTT assay
|
[PMID: 31610375]
|
HepG2
|
IC50 |
3.45 μM
Compound: Combretastatin A-4
|
Antiproliferative activity against human HepG2 cells incubated for 24 hrs by MTT assay
Antiproliferative activity against human HepG2 cells incubated for 24 hrs by MTT assay
|
[PMID: 32992133]
|
HepG2
|
IC50 |
|
Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay
Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay
|
[PMID: 28792756]
|
HepG2
|
IC50 |
|
Antiproliferative activity against human HepG2 cells after 48 hrs by sulforhodamine B assay
Antiproliferative activity against human HepG2 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 28684120]
|
HepG2
|
IC50 |
5.25 μM
Compound: 1; CA-4
|
Antiproliferative activity against human HepG2 cells assessed as inhibition of cell growth by MTT assay
Antiproliferative activity against human HepG2 cells assessed as inhibition of cell growth by MTT assay
|
[PMID: 35398303]
|
HepG2
|
IC50 |
|
Antiproliferative activity against human HepG2 cells assessed as cell growth inhibition after 48 hrs by MTT assay
Antiproliferative activity against human HepG2 cells assessed as cell growth inhibition after 48 hrs by MTT assay
|
[PMID: 33895499]
|
HepG2
|
IC50 |
|
Cytotoxicity against human HepG2 cells assessed as growth inhibition after 48 hrs by MTT assay
Cytotoxicity against human HepG2 cells assessed as growth inhibition after 48 hrs by MTT assay
|
[PMID: 27810596]
|
HepG2
|
GI50 |
|
Antiproliferation activity against human HepG2 cells assessed as cell growth inhibition measured after 72 hrs by MTT assay
Antiproliferation activity against human HepG2 cells assessed as cell growth inhibition measured after 72 hrs by MTT assay
|
[PMID: 33201714]
|
HepG2
|
IC50 |
|
Antiproliferative activity against human HepG2 cells assessed as cell growth inhibition measured after 72 hrs by MTT assay
Antiproliferative activity against human HepG2 cells assessed as cell growth inhibition measured after 72 hrs by MTT assay
|
[PMID: 34826681]
|
HepG2
|
GI50 |
|
Growth inhibition of human HepG2 cells assessed as inhibition of cell proliferation after 24 hrs by MTT assay
Growth inhibition of human HepG2 cells assessed as inhibition of cell proliferation after 24 hrs by MTT assay
|
[PMID: 26070164]
|
HK-2
|
IC50 |
|
Cytotoxicity against HK-2 cells assessed as reduction in cell growth measured after 24 hrs by microplate reader analysis
Cytotoxicity against HK-2 cells assessed as reduction in cell growth measured after 24 hrs by microplate reader analysis
|
[PMID: 35339837]
|
HL-60
|
IC50 |
|
Cytotoxicity against human HL60 cells after 48 hrs by MTT assay
Cytotoxicity against human HL60 cells after 48 hrs by MTT assay
|
10.1039/C3MD00372H
|
HL-60
|
IC50 |
0.001 μM
Compound: CA-4;1a
|
Antiproliferative activity against human HL-60 cells assessed as reduction in cell viability after 72 hrs by MTT assay
Antiproliferative activity against human HL-60 cells assessed as reduction in cell viability after 72 hrs by MTT assay
|
[PMID: 33550186]
|
HL-60
|
IC50 |
|
Antiproliferative activity against human HL-60 cells assessed as reduction in cell viability incubated for 48 hrs by MTS assay
Antiproliferative activity against human HL-60 cells assessed as reduction in cell viability incubated for 48 hrs by MTS assay
|
[PMID: 35635956]
|
HL-60
|
IC50 |
0.0019 μM
Compound: 2; CA-4
|
Antiproliferative activity against combretastatin A-4 resistant human HL-60 cells assessed as inhibition of cell growth incubated for 72 hrs by alamar blue assay
Antiproliferative activity against combretastatin A-4 resistant human HL-60 cells assessed as inhibition of cell growth incubated for 72 hrs by alamar blue assay
|
[PMID: 28254699]
|
HL-60
|
IC50 |
0.002 μM
Compound: II, CA-4
|
Cytotoxicity against human HL60 cells after 72 hrs by XTT assay
Cytotoxicity against human HL60 cells after 72 hrs by XTT assay
|
[PMID: 19939521]
|
HL-60
|
IC50 |
|
Cytotoxicity against human HL60 cells after 72 hrs by XTT assay
Cytotoxicity against human HL60 cells after 72 hrs by XTT assay
|
[PMID: 19647439]
|
HL-60
|
IC50 |
|
Antiproliferative activity against human HL60 cells after 72 hrs by XTT assay
Antiproliferative activity against human HL60 cells after 72 hrs by XTT assay
|
[PMID: 30216850]
|
HL-60
|
IC50 |
0.013 μM
Compound: Combretastatin A-4
|
Cytotoxicity against human HL60 cells assessed as inhibition of cell proliferation after 72 hrs by XTT assay
Cytotoxicity against human HL60 cells assessed as inhibition of cell proliferation after 72 hrs by XTT assay
|
[PMID: 26092446]
|
HL-60
|
IC50 |
|
Cytotoxicity against human HL60 cells after 72 hrs by XTT method
Cytotoxicity against human HL60 cells after 72 hrs by XTT method
|
[PMID: 18502133]
|
HL-60
|
IC50 |
|
Cytotoxicity against human HL60 cells after 72 hrs by MTT assay
Cytotoxicity against human HL60 cells after 72 hrs by MTT assay
|
[PMID: 20731355]
|
HL-60
|
IC50 |
|
Antiproliferative activity against human HL60 cells incubated for 48 hrs by MTS assay
Antiproliferative activity against human HL60 cells incubated for 48 hrs by MTS assay
|
[PMID: 31541870]
|
HL-60
|
IC50 |
|
Antiproliferative activity against human HL60 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay
Antiproliferative activity against human HL60 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay
|
[PMID: 31536891]
|
HL-60
|
IC50 |
|
Cytotoxicity in human HL60 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
Cytotoxicity in human HL60 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
|
[PMID: 29031074]
|
HL-60
|
IC50 |
|
Antiproliferative activity against human HL60 cells assessed as inhibition of cell proliferation incubated for 72 hrs by MTT assay
Antiproliferative activity against human HL60 cells assessed as inhibition of cell proliferation incubated for 72 hrs by MTT assay
|
[PMID: 31400707]
|
HL-60
|
IC50 |
|
Cytotoxicity against human HL60 cells after 72 hrs by MTT assay
Cytotoxicity against human HL60 cells after 72 hrs by MTT assay
|
[PMID: 23445496]
|
HL-60
|
IC50 |
1 nM
Compound: CA-4, 1a, 1
|
Antiproliferative activity against human HL60 cells after 72 hrs by MTT assay
Antiproliferative activity against human HL60 cells after 72 hrs by MTT assay
|
[PMID: 23117171]
|
HL-60
|
IC50 |
|
Antiproliferative activity against human HL60 cells assessed as growth inhibition after 72 hrs by MTT assay
Antiproliferative activity against human HL60 cells assessed as growth inhibition after 72 hrs by MTT assay
|
[PMID: 22578111]
|
HL-60
|
IC50 |
|
Cytotoxicity against human HL60 cells after 72 hrs by MTT assay
Cytotoxicity against human HL60 cells after 72 hrs by MTT assay
|
[PMID: 22136312]
|
HL-60
|
IC50 |
|
Antiproliferative activity against human HL60 cells assessed as growth inhibition after 72 hrs by MTT assay
Antiproliferative activity against human HL60 cells assessed as growth inhibition after 72 hrs by MTT assay
|
[PMID: 21663319]
|
HL-60
|
IC50 |
|
Antiproliferative activity against human HL60 cells after 72 hrs by MTT assay
Antiproliferative activity against human HL60 cells after 72 hrs by MTT assay
|
[PMID: 20420439]
|
HL-60
|
IC50 |
|
Antiproliferative activity against human HL60 cells after 72 hrs by (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide test
Antiproliferative activity against human HL60 cells after 72 hrs by (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide test
|
[PMID: 25785605]
|
HL-60
|
IC50 |
|
Antiproliferative activity against human HL-60 cells assessed as inhibition of cell growth after 72 hrs by XTT assay
Antiproliferative activity against human HL-60 cells assessed as inhibition of cell growth after 72 hrs by XTT assay
|
[PMID: 33328100]
|
HL-60
|
GI50 |
31.6 nM
Compound: 1, CA-4
|
Cytotoxicity against human HL60 cells after 48 hrs by sulforhodamine B assay
Cytotoxicity against human HL60 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 21920767]
|
HL-60
|
IC50 |
|
Cytotoxicity against human HL60 cells after 72 hrs by MTT assay
Cytotoxicity against human HL60 cells after 72 hrs by MTT assay
|
[PMID: 20690624]
|
HL-60
|
IC50 |
|
Antiproliferative activity against human HL60 cells by MTT assay
Antiproliferative activity against human HL60 cells by MTT assay
|
[PMID: 30502686]
|
HL-60
|
IC50 |
|
Antiproliferative activity against human HL60 cells after 2 days by MTT assay
Antiproliferative activity against human HL60 cells after 2 days by MTT assay
|
[PMID: 29432949]
|
HL-60(TB)
|
GI50 |
0.002 μM
Compound: CA4, NSC 613729
|
Growth inhibition of human HL-60(TB) cells after 48 hrs by SRB assay
Growth inhibition of human HL-60(TB) cells after 48 hrs by SRB assay
|
[PMID: 24387982]
|
HL-60(TB)
|
GI50 |
0.002 μM
Compound: CA4; NSC 613729
|
Cytotoxicity against human HL-60(TB) cells by SRB assay
Cytotoxicity against human HL-60(TB) cells by SRB assay
|
[PMID: 26257861]
|
HL-60(TB)
|
GI50 |
|
Growth inhibition of human HL-60(TB) cells after 48 hrs by sulforhodamine B assay
Growth inhibition of human HL-60(TB) cells after 48 hrs by sulforhodamine B assay
|
[PMID: 27031215]
|
HL-60(TB)
|
GI50 |
|
Growth inhibition of human HL-60(TB) cells after 48 hrs by sulforhodamine B assay
Growth inhibition of human HL-60(TB) cells after 48 hrs by sulforhodamine B assay
|
[PMID: 24388833]
|
HMEC-1
|
IC50 |
|
Antiproliferative activity against HMEC1 cells by MTT assay
Antiproliferative activity against HMEC1 cells by MTT assay
|
[PMID: 30502686]
|
HMEC-1
|
IC50 |
|
Antiproliferative activity against HMEC1 cells after 2 days by MTT assay
Antiproliferative activity against HMEC1 cells after 2 days by MTT assay
|
[PMID: 29432949]
|
HN-6
|
IC50 |
|
Antiproliferative activity against human HN-6 cells assessed as cell growth inhibition incubated for 72 hrs by CCK-8 assay
Antiproliferative activity against human HN-6 cells assessed as cell growth inhibition incubated for 72 hrs by CCK-8 assay
|
[PMID: 35576703]
|
HONE1 cell line
|
IC50 |
4 nM
Compound: combretastatin A-4
|
Cell growth inhibition against Hone-1 human NPC cancer cells using MTS assay
Cell growth inhibition against Hone-1 human NPC cancer cells using MTS assay
|
[PMID: 12036364]
|
HONE1 cell line
|
IC50 |
|
Inhibitory concentration against human NPC cancer cell line using tetrazolium dye reduction assay (MTT)
Inhibitory concentration against human NPC cancer cell line using tetrazolium dye reduction assay (MTT)
|
[PMID: 12467626]
|
HOP-62
|
GI50 |
0.002 μM
Compound: 2, combretastatin A-4, CA-4, NSC 613729
|
Growth inhibition of human HOP62 cells after 48 hrs by SRB assay
Growth inhibition of human HOP62 cells after 48 hrs by SRB assay
|
[PMID: 22982122]
|
HOP-62
|
GI50 |
|
Growth inhibition of human HOP62 cells after 48 hrs by sulforhodamine B assay
Growth inhibition of human HOP62 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 27031215]
|
HOP-62
|
GI50 |
0.003 μM
Compound: CA4, NSC 613729
|
Growth inhibition of human HOP62 cells after 48 hrs by SRB assay
Growth inhibition of human HOP62 cells after 48 hrs by SRB assay
|
[PMID: 24387982]
|
HOP-62
|
GI50 |
0.003 μM
Compound: CA4; NSC 613729
|
Cytotoxicity against human HOP62 cells by SRB assay
Cytotoxicity against human HOP62 cells by SRB assay
|
[PMID: 26257861]
|
HOP-62
|
GI50 |
0.15 μM
Compound: 1; CA-4
|
Antiproliferative activity against human HOP-62 cells assessed as cell growth inhibition measured after 48 hrs by SRB assay
Antiproliferative activity against human HOP-62 cells assessed as cell growth inhibition measured after 48 hrs by SRB assay
|
[PMID: 27161282]
|
HOP-62
|
GI50 |
|
Growth inhibition of human HOP62 cells after 48 hrs by sulforhodamine B assay
Growth inhibition of human HOP62 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 24388833]
|
HOP-92
|
GI50 |
0.002 μM
Compound: 2, combretastatin A-4, CA-4, NSC 613729
|
Growth inhibition of human HOP92 cells after 48 hrs by SRB assay
Growth inhibition of human HOP92 cells after 48 hrs by SRB assay
|
[PMID: 22982122]
|
HOP-92
|
GI50 |
0.003 μM
Compound: CA4, NSC 613729
|
Growth inhibition of human HOP92 cells after 48 hrs by SRB assay
Growth inhibition of human HOP92 cells after 48 hrs by SRB assay
|
[PMID: 24387982]
|
HOP-92
|
GI50 |
0.003 μM
Compound: CA4; NSC 613729
|
Cytotoxicity against human HOP92 cells by SRB assay
Cytotoxicity against human HOP92 cells by SRB assay
|
[PMID: 26257861]
|
HOP-92
|
GI50 |
|
Growth inhibition of human HOP92 cells after 48 hrs by sulforhodamine B assay
Growth inhibition of human HOP92 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 24388833]
|
Hs-578T
|
GI50 |
0.001 μM
Compound: 2, combretastatin A-4, CA-4, NSC 613729
|
Growth inhibition of human Hs578T cells after 48 hrs by SRB assay
Growth inhibition of human Hs578T cells after 48 hrs by SRB assay
|
[PMID: 22982122]
|
Hs-578T
|
IC50 |
|
Cytotoxicity against human Hs578T cells after 72 hrs by MTT assay
Cytotoxicity against human Hs578T cells after 72 hrs by MTT assay
|
[PMID: 30472600]
|
HT-1080
|
IC50 |
|
Antiproliferative activity against human HT-1080 cells assessed as inhibition of cell proliferation measured after 48 hrs by SRB assay
Antiproliferative activity against human HT-1080 cells assessed as inhibition of cell proliferation measured after 48 hrs by SRB assay
|
[PMID: 34837817]
|
HT-1080
|
IC50 |
0.0076 μM
Compound: 1a, CA-4
|
Antiproliferative activity against human HT1080 cells after 72 hrs by MTT assay
Antiproliferative activity against human HT1080 cells after 72 hrs by MTT assay
|
[PMID: 25233100]
|
HT-1080
|
IC50 |
0.008 μM
Compound: 1a, CA-4
|
Cytotoxicity against human HT1080 cells assessed as cell growth inhibition after 72 hrs by MTT assay
Cytotoxicity against human HT1080 cells assessed as cell growth inhibition after 72 hrs by MTT assay
|
[PMID: 25529737]
|
HT-1080
|
IC50 |
0.009 μM
Compound: 1; CA-4
|
Cytotoxicity against human HT1080 cells assessed as reduction in cell viability after 24 hrs by MTT assay
Cytotoxicity against human HT1080 cells assessed as reduction in cell viability after 24 hrs by MTT assay
|
[PMID: 27994764]
|
HT-1080
|
IC50 |
|
Antiproliferative activity against human HT1080 cells measured after 72 hrs by MTT assay
Antiproliferative activity against human HT1080 cells measured after 72 hrs by MTT assay
|
[PMID: 27428395]
|
HT-1080
|
IC50 |
0.011 μM
Compound: 1a; CA-4
|
Anti-proliferative activity against human HT1080 cells after 72 hrs by MTT assay
Anti-proliferative activity against human HT1080 cells after 72 hrs by MTT assay
|
10.1039/C5MD00028A
|
HT-1080
|
IC50 |
0.016 μM
Compound: 2; CA-4
|
Antiproliferative activity against human HT1080 cells assessed as reduction in cell viability after 72 hrs by MTT assay
Antiproliferative activity against human HT1080 cells assessed as reduction in cell viability after 72 hrs by MTT assay
|
10.1039/C5MD00150A
|
HT-1080
|
IC50 |
|
Antiproliferative activity against human HT-1080 cells measured after 72 hrs by MTT assay
Antiproliferative activity against human HT-1080 cells measured after 72 hrs by MTT assay
|
[PMID: 31787361]
|
HT-1080
|
IC50 |
0.016 μM
Compound: 2; CA-4
|
Antiproliferative activity against human HT1080 cells after 72 hrs by MTT assay
Antiproliferative activity against human HT1080 cells after 72 hrs by MTT assay
|
[PMID: 30245397]
|
HT-1080
|
IC50 |
0.051 μM
Compound: 1; CA-4
|
Antiproliferative activity against human HT1080 cells measured after 72 hrs by MTT assay
Antiproliferative activity against human HT1080 cells measured after 72 hrs by MTT assay
|
[PMID: 30901597]
|
HT-1080
|
IC50 |
|
Cytotoxicity against human HT1080 cells assessed as cell viability after 72 hrs by resazurin reduction assay
Cytotoxicity against human HT1080 cells assessed as cell viability after 72 hrs by resazurin reduction assay
|
[PMID: 26599530]
|
HT-1080
|
IC50 |
|
Antiproliferative activity against human HT1080 cells assessed as cell growth inhibition after 48 hrs by sulforhodamine B assay
Antiproliferative activity against human HT1080 cells assessed as cell growth inhibition after 48 hrs by sulforhodamine B assay
|
[PMID: 26069928]
|
HT-1080
|
IC50 |
|
Antiproliferative activity against human HT-1080 cells assessed as reduction in cell viability measured after 48 hrs by sulforhodamine B assay
Antiproliferative activity against human HT-1080 cells assessed as reduction in cell viability measured after 48 hrs by sulforhodamine B assay
|
[PMID: 33472119]
|
HT-22
|
CC50 |
|
Cytotoxicity against mouse HT22 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
Cytotoxicity against mouse HT22 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
|
[PMID: 32832031]
|
HT-22
|
CC50 |
|
Cytotoxicity against mouse HT-22 cells measured after 48 hrs by MTT assay
Cytotoxicity against mouse HT-22 cells measured after 48 hrs by MTT assay
|
[PMID: 36150341]
|
HT-29
|
IC50 |
|
Antiproliferative activity against human HT-29 cells assessed as inhibition of cell proliferation measured after 48 hrs by SRB assay
Antiproliferative activity against human HT-29 cells assessed as inhibition of cell proliferation measured after 48 hrs by SRB assay
|
[PMID: 34837817]
|
HT-29
|
IC50 |
> 10 μM
Compound: 2, CSA4
|
Antiproliferative activity against human HT-29 cells assessed as growth inhibition after 48 hrs by MTT assay
Antiproliferative activity against human HT-29 cells assessed as growth inhibition after 48 hrs by MTT assay
|
[PMID: 22044164]
|
HT-29
|
IC50 |
|
Antiproliferative activity against human HT-29 cells after 72 hrs by CellTiter Glo assay
Antiproliferative activity against human HT-29 cells after 72 hrs by CellTiter Glo assay
|
[PMID: 35797900]
|
HT-29
|
IC50 |
|
Growth inhibition of combretastatin A-4 resistant human HT-29 cells after 72 hrs by MTT assay
Growth inhibition of combretastatin A-4 resistant human HT-29 cells after 72 hrs by MTT assay
|
[PMID: 27116710]
|
HT-29
|
IC50 |
> 8000 nM
Compound: 1; CA-4
|
Antiproliferative activity against human HT-29 cells assessed as cell viability after 24 hrs by Celltiter-Glo assay
Antiproliferative activity against human HT-29 cells assessed as cell viability after 24 hrs by Celltiter-Glo assay
|
[PMID: 33038796]
|
HT-29
|
IC50 |
|
Antiproliferative activity against human HT-29 cells after 72 hrs by MTS assay
Antiproliferative activity against human HT-29 cells after 72 hrs by MTS assay
|
[PMID: 30525602]
|
HT-29
|
IC50 |
|
Growth inhibition of human HT-29 cells by MTT assay
Growth inhibition of human HT-29 cells by MTT assay
|
[PMID: 25689111]
|
HT-29
|
IC50 |
|
Cytotoxicity against human HT29 cells after 72 hrs by XTT method
Cytotoxicity against human HT29 cells after 72 hrs by XTT method
|
[PMID: 18502133]
|
HT-29
|
IC50 |
|
Antiproliferative activity against human HT-29 cells after 72 hrs by MTS assay
Antiproliferative activity against human HT-29 cells after 72 hrs by MTS assay
|
[PMID: 21112130]
|
HT-29
|
IC50 |
0.03 μM
Compound: Combretastatin A-4
|
Cytotoxicity against human HT-29 cells assessed as inhibition of cell proliferation after 72 hrs by XTT assay
Cytotoxicity against human HT-29 cells assessed as inhibition of cell proliferation after 72 hrs by XTT assay
|
[PMID: 26092446]
|
HT-29
|
IC50 |
|
Antiproliferative activity against human HT-29 cells after 72 hrs by XTT assay
Antiproliferative activity against human HT-29 cells after 72 hrs by XTT assay
|
[PMID: 30216850]
|
HT-29
|
IC50 |
0.032 μM
Compound: II, CA-4
|
Cytotoxicity against human HT-29 cells after 72 hrs by XTT assay
Cytotoxicity against human HT-29 cells after 72 hrs by XTT assay
|
[PMID: 19939521]
|
HT-29
|
IC50 |
|
Cytotoxicity against human HT-29 cells after 72 hrs by XTT assay
Cytotoxicity against human HT-29 cells after 72 hrs by XTT assay
|
[PMID: 19647439]
|
HT-29
|
IC50 |
|
Cytotoxicity against human HT-29 cells after 72 hrs by XTT assay
Cytotoxicity against human HT-29 cells after 72 hrs by XTT assay
|
[PMID: 18790642]
|
HT-29
|
IC50 |
0.049 μM
Compound: 1; CA-4
|
Cytotoxicity against human HT-29 cells after 48 hrs by MTT assay
Cytotoxicity against human HT-29 cells after 48 hrs by MTT assay
|
[PMID: 26970659]
|
HT-29
|
IC50 |
|
Cytotoxicity against human HT-29 cells after 72 hrs by MTT assay
Cytotoxicity against human HT-29 cells after 72 hrs by MTT assay
|
[PMID: 28622907]
|
HT-29
|
IC50 |
|
Antiproliferative activity against human HT-29 cells after 72 hrs by MTT assay
Antiproliferative activity against human HT-29 cells after 72 hrs by MTT assay
|
[PMID: 29407949]
|
HT-29
|
GI50 |
0.1 μM
Compound: CA4, NSC 613729
|
Growth inhibition of human HT-29 cells after 48 hrs by SRB assay
Growth inhibition of human HT-29 cells after 48 hrs by SRB assay
|
[PMID: 24387982]
|
HT-29
|
GI50 |
0.1 μM
Compound: 2, combretastatin A-4, CA-4, NSC 613729
|
Growth inhibition of human HT-29 cells after 48 hrs by SRB assay
Growth inhibition of human HT-29 cells after 48 hrs by SRB assay
|
[PMID: 22982122]
|
HT-29
|
GI50 |
0.1 μM
Compound: CA4; NSC 613729
|
Cytotoxicity against human HT-29 cells by SRB assay
Cytotoxicity against human HT-29 cells by SRB assay
|
[PMID: 26257861]
|
HT-29
|
GI50 |
|
Growth inhibition of human HT-29 cells after 48 hrs by sulforhodamine B assay
Growth inhibition of human HT-29 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 27031215]
|
HT-29
|
IC50 |
0.18 μM
Compound: 1, CA-4
|
Cytotoxicity against human HT-29 cells assessed as growth inhibition after 48 hrs by MTT assay
Cytotoxicity against human HT-29 cells assessed as growth inhibition after 48 hrs by MTT assay
|
[PMID: 23566762]
|
HT-29
|
GI50 |
|
Antiproliferative activity against human HT-29 cells incubated for 48 hrs by MTT assay
Antiproliferative activity against human HT-29 cells incubated for 48 hrs by MTT assay
|
[PMID: 32832031]
|
HT-29
|
GI50 |
|
Cytotoxicity against human HT-29 cells assessed as reduction in cell growth after 48 hrs by SRB assay
Cytotoxicity against human HT-29 cells assessed as reduction in cell growth after 48 hrs by SRB assay
|
[PMID: 27040661]
|
HT-29
|
IC50 |
|
Antiproliferative activity against human HT29 cells incubated for 48 hrs by MTT assay
Antiproliferative activity against human HT29 cells incubated for 48 hrs by MTT assay
|
[PMID: 32035399]
|
HT-29
|
IC50 |
|
Cytotoxicity against human HT-29 cells by alamar blue assay
Cytotoxicity against human HT-29 cells by alamar blue assay
|
[PMID: 22137934]
|
HT-29
|
IC50 |
|
Antiproliferative activity against human HT-29 cells measured after 48 hrs by MTT assay
Antiproliferative activity against human HT-29 cells measured after 48 hrs by MTT assay
|
[PMID: 36150341]
|
HT-29
|
IC50 |
|
Cytotoxicity against human HT-29 cells assessed as cell viability after 72 hrs by resazurin reduction assay
Cytotoxicity against human HT-29 cells assessed as cell viability after 72 hrs by resazurin reduction assay
|
[PMID: 26599530]
|
HT-29
|
IC50 |
|
Cytotoxicity against human HT-29 cells assessed as reduction in cell viability measured after 24 hrs by MTT assay
Cytotoxicity against human HT-29 cells assessed as reduction in cell viability measured after 24 hrs by MTT assay
|
[PMID: 35447432]
|
HT-29
|
IC50 |
|
Antiproliferative activity against human HT-29 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
Antiproliferative activity against human HT-29 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
|
[PMID: 36252396]
|
HT-29
|
IC50 |
|
Cytotoxicity against human HT-29 cells assessed as reduction in cell viability after 72 hrs by MTT assay
Cytotoxicity against human HT-29 cells assessed as reduction in cell viability after 72 hrs by MTT assay
|
[PMID: 30108866]
|
HT-29
|
IC50 |
0.93 μM
Compound: Combretastatin A-4
|
Cytotoxicity against human HT-29 cells after 48 hrs by MTT assay
Cytotoxicity against human HT-29 cells after 48 hrs by MTT assay
|
[PMID: 30108703]
|
HT-29
|
IC50 |
0.93 μM
Compound: Combretastatin-A4
|
Cytotoxicity against human HT-29 cells after 48 hrs by MTT assay
Cytotoxicity against human HT-29 cells after 48 hrs by MTT assay
|
[PMID: 27487568]
|
HT-29
|
IC50 |
0.93 μM
Compound: 2a, CA-4
|
Cytotoxicity against human HT-29 cells after 48 hrs by MTT assay
Cytotoxicity against human HT-29 cells after 48 hrs by MTT assay
|
[PMID: 22543234]
|
HT-29
|
IC50 |
|
Cytotoxicity against human HT-29 cells after 48 hrs by sulforhodamine B assay
Cytotoxicity against human HT-29 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 23810282]
|
HT-29
|
IC50 |
|
Cytotoxicity against human HT-29 cells after 48 hrs by MTT assay
Cytotoxicity against human HT-29 cells after 48 hrs by MTT assay
|
[PMID: 24238904]
|
HT-29
|
IC50 |
|
Antiproliferative activity against human HT29 cells assessed as cell growth inhibition after 48 hrs by MTT assay
Antiproliferative activity against human HT29 cells assessed as cell growth inhibition after 48 hrs by MTT assay
|
[PMID: 33895499]
|
HT-29
|
IC50 |
|
Cytotoxicity against human HT-29 cells assessed as inhibition of cell growth after 48 hrs by MTT assay
Cytotoxicity against human HT-29 cells assessed as inhibition of cell growth after 48 hrs by MTT assay
|
[PMID: 30448234]
|
HT-29
|
IC50 |
|
Cytotoxicity against human HT-29 cells assessed as growth inhibition after 48 hrs by MTT assay
Cytotoxicity against human HT-29 cells assessed as growth inhibition after 48 hrs by MTT assay
|
[PMID: 27810596]
|
HT-29
|
IC50 |
1.96 μM
Compound: 1; CA-4
|
Antiproliferative activity against human HT-29 cells assessed as inhibition of cell growth by MTT assay
Antiproliferative activity against human HT-29 cells assessed as inhibition of cell growth by MTT assay
|
[PMID: 35398303]
|
HT-29
|
IC50 |
|
Antiproliferative activity against human HT-29 cells assessed as reduction in cell growth after 48 hrs by MTT assay
Antiproliferative activity against human HT-29 cells assessed as reduction in cell growth after 48 hrs by MTT assay
|
[PMID: 33022479]
|
HT-29
|
GI50 |
|
Growth inhibition of human HT-29 cells after 48 hrs by sulforhodamine B assay
Growth inhibition of human HT-29 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 24388833]
|
HT-29
|
IC50 |
118 nM
Compound: 1, combretastatin A-4, CA-4
|
Cytotoxic activity against human HT29 cells after 72 hrs by sulforhodamine B test
Cytotoxic activity against human HT29 cells after 72 hrs by sulforhodamine B test
|
[PMID: 18396857]
|
HT-29
|
IC50 |
|
Cytotoxicity against human HT29 cells by sulforhodamine B test
Cytotoxicity against human HT29 cells by sulforhodamine B test
|
[PMID: 18783207]
|
HT-29
|
IC50 |
12000 nM
Compound: 2, CA-4
|
Cytotoxicity against human HT-29 cells after 48 hrs by resazurin assay
Cytotoxicity against human HT-29 cells after 48 hrs by resazurin assay
|
[PMID: 22727370]
|
HT-29
|
IC50 |
|
Cytotoxicity against human HT-29 cells assessed as growth inhibition after 48 hrs by MTT assay
Cytotoxicity against human HT-29 cells assessed as growth inhibition after 48 hrs by MTT assay
|
[PMID: 23214452]
|
HT-29
|
IC50 |
|
Antiproliferative activity against CA-4-resistant human HT-29 cells measured after 72 hrs by MTT assay
Antiproliferative activity against CA-4-resistant human HT-29 cells measured after 72 hrs by MTT assay
|
[PMID: 27187864]
|
HT-29
|
IC50 |
|
Cytotoxicity against human HT-29 cells assessed as growth inhibition after 72 hrs by MTT assay
Cytotoxicity against human HT-29 cells assessed as growth inhibition after 72 hrs by MTT assay
|
[PMID: 23981529]
|
HT-29
|
IC50 |
|
Antiproliferative activity against human HT-29 cells assessed as reduction in cell viability after 72 hrs by MTT assay
Antiproliferative activity against human HT-29 cells assessed as reduction in cell viability after 72 hrs by MTT assay
|
[PMID: 33550186]
|
HT-29
|
IC50 |
|
Antiproliferative activity against human HT-29 cells after 72 hrs by MTT assay
Antiproliferative activity against human HT-29 cells after 72 hrs by MTT assay
|
[PMID: 30633509]
|
HT-29
|
IC50 |
|
Antiproliferative activity against human HT-29 cells assessed as reduction in cell viability after 72 hrs by MTT assay
Antiproliferative activity against human HT-29 cells assessed as reduction in cell viability after 72 hrs by MTT assay
|
[PMID: 31610372]
|
HT-29
|
IC50 |
|
Antiproliferative activity against human HT-29 cells assessed as inhibition of cell growth after 72 hrs by XTT assay
Antiproliferative activity against human HT-29 cells assessed as inhibition of cell growth after 72 hrs by XTT assay
|
[PMID: 33328100]
|
HT-29
|
IC50 |
3100 nM
Compound: 1a; CA-4
|
Antiproliferative activity against human HT-29 cells assessed as inhibition of cell proliferation incubated for 72 hrs by MTT assay
Antiproliferative activity against human HT-29 cells assessed as inhibition of cell proliferation incubated for 72 hrs by MTT assay
|
[PMID: 31400707]
|
HT-29
|
IC50 |
3100 nM
Compound: 1a, CA-4
|
Growth inhibition of human HT-29 cells after 72 hrs by MTT assay
Growth inhibition of human HT-29 cells after 72 hrs by MTT assay
|
[PMID: 25025853]
|
HT-29
|
IC50 |
3100 nM
Compound: 1, CA-4
|
Cytotoxicity against human HT-29 cells after 72 hrs by MTT assay
Cytotoxicity against human HT-29 cells after 72 hrs by MTT assay
|
[PMID: 23445496]
|
HT-29
|
IC50 |
3100 nM
Compound: CA-4, 1a, 1
|
Antiproliferative activity against human HT-29 cells after 72 hrs by MTT assay
Antiproliferative activity against human HT-29 cells after 72 hrs by MTT assay
|
[PMID: 23117171]
|
HT-29
|
IC50 |
3100 nM
Compound: 1, CA-4
|
Antiproliferative activity against human HT-29 cells assessed as growth inhibition after 72 hrs by MTT assay
Antiproliferative activity against human HT-29 cells assessed as growth inhibition after 72 hrs by MTT assay
|
[PMID: 22578111]
|
HT-29
|
IC50 |
|
Cytotoxicity against human HT-29 cells after 72 hrs by MTT assay
Cytotoxicity against human HT-29 cells after 72 hrs by MTT assay
|
[PMID: 22136312]
|
HT-29
|
IC50 |
3100 nM
Compound: 1, CA-4
|
Antiproliferative activity against human HT-29 cells assessed as growth inhibition after 72 hrs by MTT assay
Antiproliferative activity against human HT-29 cells assessed as growth inhibition after 72 hrs by MTT assay
|
[PMID: 21663319]
|
HT-29
|
IC50 |
3100 nM
Compound: 1a, CA-4
|
Antiproliferative activity against human HT-29 cells after 72 hrs by (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide test
Antiproliferative activity against human HT-29 cells after 72 hrs by (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide test
|
[PMID: 25785605]
|
HT-29
|
IC50 |
|
Cytotoxicity against human HT-29 cells after 72 hrs by MTT assay
Cytotoxicity against human HT-29 cells after 72 hrs by MTT assay
|
[PMID: 20731355]
|
HT-29
|
IC50 |
|
Antiproliferative activity against human HT-29 cells measured after 72 hrs by MTT assay
Antiproliferative activity against human HT-29 cells measured after 72 hrs by MTT assay
|
[PMID: 36471625]
|
HT-29
|
IC50 |
4.165 μM
Compound: CA-4; D-613729
|
Antiproliferative activity against human HT-29 cells assessed as reduction in cell viability after 72 hrs by alamar blue assay
Antiproliferative activity against human HT-29 cells assessed as reduction in cell viability after 72 hrs by alamar blue assay
|
[PMID: 31954879]
|
HT-29
|
IC50 |
4.165 μM
Compound: 2; CA-4
|
Antiproliferative activity against combretastatin A-4 resistant human HT-29 cells assessed as inhibition of cell growth incubated for 72 hrs by SRB assay
Antiproliferative activity against combretastatin A-4 resistant human HT-29 cells assessed as inhibition of cell growth incubated for 72 hrs by SRB assay
|
[PMID: 28254699]
|
HT-29
|
IC50 |
4.2 μM
Compound: 1a, CoA4
|
Cytotoxicity against human HT-29 cells assessed as growth inhibition after 3 days by MTT assay
Cytotoxicity against human HT-29 cells assessed as growth inhibition after 3 days by MTT assay
|
[PMID: 24145138]
|
HT-29
|
IC50 |
|
Cytotoxicity against human HT-29 cells assessed as inhibition of cell growth after 72 hrs by MTT assay
Cytotoxicity against human HT-29 cells assessed as inhibition of cell growth after 72 hrs by MTT assay
|
[PMID: 25240870]
|
HT-29
|
IC50 |
|
Antiproliferative activity against human HT-29 cells by MTT assay
Antiproliferative activity against human HT-29 cells by MTT assay
|
[PMID: 30502686]
|
HT-29
|
IC50 |
|
Antiproliferative activity against human HT-29 cells after 2 days by MTT assay
Antiproliferative activity against human HT-29 cells after 2 days by MTT assay
|
[PMID: 29432949]
|
HT-29
|
IC50 |
|
Cytotoxicity against human HT29 cells after 72 hrs by MTT assay
Cytotoxicity against human HT29 cells after 72 hrs by MTT assay
|
[PMID: 17373779]
|
HT-29
|
IC50 |
|
Antiproliferative activity against human HT-29 cells assessed as reduction in cell viability measured after 48 hrs by sulforhodamine B assay
Antiproliferative activity against human HT-29 cells assessed as reduction in cell viability measured after 48 hrs by sulforhodamine B assay
|
[PMID: 33472119]
|
HT-29
|
IC50 |
|
Growth inhibition of combretastatin-resistant human HT-29 cells after 48 hrs by SRB assay
Growth inhibition of combretastatin-resistant human HT-29 cells after 48 hrs by SRB assay
|
[PMID: 24900453]
|
HT-29
|
IC50 |
|
Antiproliferative activity against human HT29 cell line by methylene blue dye assay
Antiproliferative activity against human HT29 cell line by methylene blue dye assay
|
[PMID: 17034147]
|
HT-29
|
IC50 |
|
Antiproliferative activity against human HT-29 cells assessed as cell growth inhibition after 48 hrs by sulforhodamine B assay
Antiproliferative activity against human HT-29 cells assessed as cell growth inhibition after 48 hrs by sulforhodamine B assay
|
[PMID: 26069928]
|
HT-29
|
IC50 |
|
Antiproliferative activity against human HT-29 cells after 48 hrs by SRB assay
Antiproliferative activity against human HT-29 cells after 48 hrs by SRB assay
|
[PMID: 21920638]
|
HT-29
|
IC50 |
|
Antiproliferative activity against human HT-29 cells after 48 hrs by sulforhodamine B assay
Antiproliferative activity against human HT-29 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 21604746]
|
HT-29
|
GI50 |
|
Cytotoxicity against human HT29 cells after 48 hrs by sulforhodamine B assay
Cytotoxicity against human HT29 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 21920767]
|
HT-29
|
IC50 |
|
Antiproliferative activity against human HT-29 cells after 72 hrs by methylene blue dye assay
Antiproliferative activity against human HT-29 cells after 72 hrs by methylene blue dye assay
|
[PMID: 20148562]
|
HT-29
|
IC50 |
|
Cytotoxicity against human HT-29 cells after 72 hrs by methylene blue assay
Cytotoxicity against human HT-29 cells after 72 hrs by methylene blue assay
|
[PMID: 24657567]
|
HT-29
|
IC50 |
|
Growth inhibition of human HT-29 cells after 72 hrs by methylene blue assay
Growth inhibition of human HT-29 cells after 72 hrs by methylene blue assay
|
[PMID: 22060033]
|
HT-29
|
IC50 |
|
Antiproliferative activity against human HT-29 cells after 72 hrs by methylene blue assay
Antiproliferative activity against human HT-29 cells after 72 hrs by methylene blue assay
|
[PMID: 21641700]
|
Huh-7
|
CC50 |
|
Cytotoxicity against human HuH7 cells assessed as reduction in cell viability measured after 72 hrs by cell titer blue assay
Cytotoxicity against human HuH7 cells assessed as reduction in cell viability measured after 72 hrs by cell titer blue assay
|
[PMID: 31413794]
|
Huh-7
|
CC50 |
|
Cytotoxicity against human HuH7 cells assessed as reduction in cell viability measured after 24 hrs by cell titer blue assay
Cytotoxicity against human HuH7 cells assessed as reduction in cell viability measured after 24 hrs by cell titer blue assay
|
[PMID: 31413794]
|
Huh-7
|
IC50 |
|
Antiproliferative activity against human Huh-7 cells assessed as reduction in cell viability measured after 48 hrs by MTT assay
Antiproliferative activity against human Huh-7 cells assessed as reduction in cell viability measured after 48 hrs by MTT assay
|
[PMID: 32339854]
|
Huh-7
|
IC50 |
|
Antiproliferative activity against human HuH7 cells incubated for 24 hrs by sulforhodamine B assay
Antiproliferative activity against human HuH7 cells incubated for 24 hrs by sulforhodamine B assay
|
[PMID: 26938120]
|
HuTu80
|
IC50 |
|
Antiproliferative activity in human HuTu 80 cells assessed as cell viability after 72 hrs by MTT assay
Antiproliferative activity in human HuTu 80 cells assessed as cell viability after 72 hrs by MTT assay
|
[PMID: 22329561]
|
HUVEC
|
IC50 |
> 100000 nM
Compound: CA-4
|
Cytotoxicity against HUVEC assessed as reduction in cell viability after 72 hrs by MTT assay
Cytotoxicity against HUVEC assessed as reduction in cell viability after 72 hrs by MTT assay
|
[PMID: 31610372]
|
HUVEC
|
IC50 |
0.005 μM
Compound: 1, CA-4
|
Cytotoxicity against HUVEC after 72 hrs by crystal violet staining
Cytotoxicity against HUVEC after 72 hrs by crystal violet staining
|
[PMID: 19954252]
|
HUVEC
|
IC50 |
0.005 μM
Compound: Combretastatin A-4, IODWF
|
Cytotoxicity against HUVEC assessed as cell viability after 48 hrs by MTT assay
Cytotoxicity against HUVEC assessed as cell viability after 48 hrs by MTT assay
|
[PMID: 24012378]
|
HUVEC
|
IC50 |
0.01 μM
Compound: 1, CA-4
|
Vascular disrupting activity in HUVEC assessed as change in cell morphology with detachment form substrate after 1 hr by crystal violet staining-based inverted light microscopy
Vascular disrupting activity in HUVEC assessed as change in cell morphology with detachment form substrate after 1 hr by crystal violet staining-based inverted light microscopy
|
[PMID: 19954252]
|
HUVEC
|
IC50 |
|
Cytotoxicity against HUVEC after 1 hr by crystal violet staining
Cytotoxicity against HUVEC after 1 hr by crystal violet staining
|
[PMID: 19954252]
|
HUVEC
|
EC50 |
0.9 nM
Compound: 5, (Z)-5, CA-4, Combretastatin A-4
|
Antivascular activity in growth factor-induced HUVEC after 45 hrs xCELLigence analysis
Antivascular activity in growth factor-induced HUVEC after 45 hrs xCELLigence analysis
|
10.1039/C0MD00095G
|
HUVEC
|
IC50 |
|
Cytotoxicity against HUVEC cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay
Cytotoxicity against HUVEC cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay
|
[PMID: 31954880]
|
HUVEC
|
IC50 |
|
Growth inhibition of HUVEC cells after 48 hrs by MTT assay
Growth inhibition of HUVEC cells after 48 hrs by MTT assay
|
[PMID: 22044164]
|
HUVEC
|
IC50 |
|
Antiproliferative activity against HUVEC after 72 hrs by MTS assay
Antiproliferative activity against HUVEC after 72 hrs by MTS assay
|
[PMID: 30525602]
|
HUVEC
|
EC50 |
1.9 nM
Compound: 5, (Z)-5, CA-4, Combretastatin A-4
|
Antivascular activity in growth factor-induced HUVEC after 24 hrs xCELLigence analysis
Antivascular activity in growth factor-induced HUVEC after 24 hrs xCELLigence analysis
|
10.1039/C0MD00095G
|
HUVEC
|
IC50 |
2.2 nM
Compound: 1, CA-4, combretastatin
|
Antivascular activity against HUVEC cells assessed as cell growth inhibition measured every 30 mins for 21 hrs by xCELLigence assay
Antivascular activity against HUVEC cells assessed as cell growth inhibition measured every 30 mins for 21 hrs by xCELLigence assay
|
[PMID: 22304851]
|
HUVEC
|
IC50 |
|
Antivascular activity against HUVEC after 24 hrs by xCELLigence assays
Antivascular activity against HUVEC after 24 hrs by xCELLigence assays
|
[PMID: 24900453]
|
HUVEC
|
IC50 |
|
Cytotoxicity against HUVEC after 48 hrs using resazurin by microplate fluorometer analysis
Cytotoxicity against HUVEC after 48 hrs using resazurin by microplate fluorometer analysis
|
[PMID: 22185476]
|
HUVEC
|
IC50 |
|
Cytotoxicity against HUVEC assessed as cell viability after 4 days by MTS assay
Cytotoxicity against HUVEC assessed as cell viability after 4 days by MTS assay
|
[PMID: 24210503]
|
HUVEC
|
EC50 |
3.2 nM
Compound: 5, (Z)-5, CA-4, Combretastatin A-4
|
Antiproliferative activity against growth factor-induced HUVEC assessed as growth inhibition after 48 hrs by MTS assay
Antiproliferative activity against growth factor-induced HUVEC assessed as growth inhibition after 48 hrs by MTS assay
|
10.1039/C0MD00095G
|
HUVEC
|
IC50 |
3.34 nM
Compound: 1, CA-4
|
Antiproliferative activity against activated HUVECs after 48 hrs by CCK-8 assay
Antiproliferative activity against activated HUVECs after 48 hrs by CCK-8 assay
|
[PMID: 23360369]
|
HUVEC
|
IC50 |
|
Antiproliferative activity against HUVEC grown in presence of growth factors after 48 hrs by spectrophotometry
Antiproliferative activity against HUVEC grown in presence of growth factors after 48 hrs by spectrophotometry
|
[PMID: 21774499]
|
HUVEC
|
IC50 |
|
Antiproliferative activity against HUVEC grown in absence of growth factors after 48 hrs by spectrophotometry
Antiproliferative activity against HUVEC grown in absence of growth factors after 48 hrs by spectrophotometry
|
[PMID: 21774499]
|
HUVEC
|
IC50 |
4.17 nM
Compound: 7; CA-4
|
Cytotoxicity against HUVEC assessed as reduction in cell viability incubated for 72 hrs by MTS assay
Cytotoxicity against HUVEC assessed as reduction in cell viability incubated for 72 hrs by MTS assay
|
[PMID: 31401010]
|
HUVEC
|
IC50 |
|
Antiproliferative activity against quesicent HUVECs after 48 hrs by CCK-8 assay
Antiproliferative activity against quesicent HUVECs after 48 hrs by CCK-8 assay
|
[PMID: 23360369]
|
IGROV-1
|
GI50 |
0.015 μM
Compound: CA4, NSC 613729
|
Growth inhibition of human IGROV1 cells after 48 hrs by SRB assay
Growth inhibition of human IGROV1 cells after 48 hrs by SRB assay
|
[PMID: 24387982]
|
IGROV-1
|
GI50 |
0.015 μM
Compound: 2, combretastatin A-4, CA-4, NSC 613729
|
Growth inhibition of human IGROV1 cells after 48 hrs by SRB assay
Growth inhibition of human IGROV1 cells after 48 hrs by SRB assay
|
[PMID: 22982122]
|
IGROV-1
|
GI50 |
0.015 μM
Compound: CA4; NSC 613729
|
Cytotoxicity against human IGROV1 cells by SRB assay
Cytotoxicity against human IGROV1 cells by SRB assay
|
[PMID: 26257861]
|
IGROV-1
|
GI50 |
|
Growth inhibition of human IGROV1 cells after 48 hrs by sulforhodamine B assay
Growth inhibition of human IGROV1 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 24388833]
|
IMR-32
|
IC50 |
5.72 μM
Compound: Combretastatin
|
Antiproliferative activity in human IMR32 cells assessed as reduction in cell number incubated for 48 hrs by SRB assay
Antiproliferative activity in human IMR32 cells assessed as reduction in cell number incubated for 48 hrs by SRB assay
|
[PMID: 30108756]
|
Ishikawa
|
IC50 |
|
Cytotoxicity against human Ishikawa cells after 48 hrs by MTT assay
Cytotoxicity against human Ishikawa cells after 48 hrs by MTT assay
|
10.1039/C3MD00372H
|
Jurkat
|
IC50 |
|
Antiproliferative activity against human Jurkat cells after 72 hrs by MTT assay
Antiproliferative activity against human Jurkat cells after 72 hrs by MTT assay
|
[PMID: 30633509]
|
Jurkat
|
IC50 |
|
Growth inhibition of human Jurkat cells after 72 hrs by MTT assay
Growth inhibition of human Jurkat cells after 72 hrs by MTT assay
|
[PMID: 25025853]
|
Jurkat
|
IC50 |
|
Cytotoxicity against human Jurkat cells after 72 hrs by MTT assay
Cytotoxicity against human Jurkat cells after 72 hrs by MTT assay
|
[PMID: 23445496]
|
Jurkat
|
IC50 |
5 nM
Compound: CA-4, 1a, 1
|
Antiproliferative activity against human Jurkat cells after 72 hrs by MTT assay
Antiproliferative activity against human Jurkat cells after 72 hrs by MTT assay
|
[PMID: 23117171]
|
Jurkat
|
IC50 |
|
Antiproliferative activity against human Jurkat cells assessed as growth inhibition after 72 hrs by MTT assay
Antiproliferative activity against human Jurkat cells assessed as growth inhibition after 72 hrs by MTT assay
|
[PMID: 22578111]
|
Jurkat
|
IC50 |
|
Cytotoxicity against human Jurkat cells after 72 hrs by MTT assay
Cytotoxicity against human Jurkat cells after 72 hrs by MTT assay
|
[PMID: 22136312]
|
Jurkat
|
IC50 |
|
Antiproliferative activity against human Jurkat cells assessed as growth inhibition after 72 hrs by MTT assay
Antiproliferative activity against human Jurkat cells assessed as growth inhibition after 72 hrs by MTT assay
|
[PMID: 21663319]
|
Jurkat
|
IC50 |
|
Antiproliferative activity against human Jurkat cells after 72 hrs by MTT assay
Antiproliferative activity against human Jurkat cells after 72 hrs by MTT assay
|
[PMID: 20420439]
|
Jurkat
|
IC50 |
|
Antiproliferative activity against human Jurkat cells after 72 hrs by (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide test
Antiproliferative activity against human Jurkat cells after 72 hrs by (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide test
|
[PMID: 25785605]
|
Jurkat E6.1
|
IC50 |
0.00608 μM
Compound: 3, CA4
|
Anticancer activity against human Jurkat E6-1 cells assessed as reduction in cell proliferation after 48 hrs by WST-1 assay
Anticancer activity against human Jurkat E6-1 cells assessed as reduction in cell proliferation after 48 hrs by WST-1 assay
|
[PMID: 25466200]
|
K562
|
IC50 |
|
Growth inhibition of human K562 cells measured after 72 hrs by MTT assay
Growth inhibition of human K562 cells measured after 72 hrs by MTT assay
|
[PMID: 27187864]
|
K562
|
GI50 |
0.002 μM
Compound: CA4, NSC 613729
|
Growth inhibition of human K562 cells after 48 hrs by SRB assay
Growth inhibition of human K562 cells after 48 hrs by SRB assay
|
[PMID: 24387982]
|
K562
|
GI50 |
0.002 μM
Compound: 2, combretastatin A-4, CA-4, NSC 613729
|
Growth inhibition of human K562 cells after 48 hrs by SRB assay
Growth inhibition of human K562 cells after 48 hrs by SRB assay
|
[PMID: 22982122]
|
K562
|
GI50 |
0.002 μM
Compound: CA4; NSC 613729
|
Cytotoxicity against human K562 cells by SRB assay
Cytotoxicity against human K562 cells by SRB assay
|
[PMID: 26257861]
|
K562
|
GI50 |
|
Growth inhibition of human K562 cells after 48 hrs by sulforhodamine B assay
Growth inhibition of human K562 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 27031215]
|
K562
|
IC50 |
0.003 μM
Compound: Combretastatin A-4
|
Antiproliferative activity against human K562 cells assessed as reduction in cell proliferation after 3 days by 3H-thymidine incorporation assay
Antiproliferative activity against human K562 cells assessed as reduction in cell proliferation after 3 days by 3H-thymidine incorporation assay
|
[PMID: 27212068]
|
K562
|
IC50 |
|
Antiproliferative activity against human K562 cells assessed as inhibition of cell growth measured after 72 hrs by MTT assay
Antiproliferative activity against human K562 cells assessed as inhibition of cell growth measured after 72 hrs by MTT assay
|
[PMID: 35926141]
|
K562
|
IC50 |
0.007 μM
Compound: 1; CA-4
|
Antiproliferative activity against human K562 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
Antiproliferative activity against human K562 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
|
[PMID: 33676300]
|
K562
|
IC50 |
0.007 μM
Compound: 1; CA-4
|
Antiproliferative activity against human K562 cells after 72 hrs by MTT assay
Antiproliferative activity against human K562 cells after 72 hrs by MTT assay
|
[PMID: 30530194]
|
K562
|
IC50 |
0.009 μM
Compound: 1; CA-4
|
Antiproliferative activity against human K562 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
Antiproliferative activity against human K562 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
|
[PMID: 32853870]
|
K562
|
IC50 |
0.01 μM
Compound: 1, CA-4
|
Cytotoxicity against human K562 cells after 5 days by MTT assay
Cytotoxicity against human K562 cells after 5 days by MTT assay
|
[PMID: 20708408]
|
K562
|
IC50 |
0.01 μM
Compound: 1, CA-4
|
Cytotoxicity against human K562 cells after 5 days by MTT assay
Cytotoxicity against human K562 cells after 5 days by MTT assay
|
[PMID: 18396050]
|
K562
|
IC50 |
0.011 μM
Compound: 1; CA-4
|
Antiproliferative activity against human K562 cells assessed as reduction in cell viability after 72 hrs by MTT assay
Antiproliferative activity against human K562 cells assessed as reduction in cell viability after 72 hrs by MTT assay
|
[PMID: 30981112]
|
K562
|
IC50 |
|
Antiproliferative activity against human K562 cells after 72 hrs by MTT assay
Antiproliferative activity against human K562 cells after 72 hrs by MTT assay
|
[PMID: 30525584]
|
K562
|
IC50 |
|
Antiproliferative activity against human K562 cells after 72 hrs by MTT assay
Antiproliferative activity against human K562 cells after 72 hrs by MTT assay
|
[PMID: 29172084]
|
K562
|
IC50 |
0.015 μM
Compound: CA-4; 1
|
Antiproliferative activity against human K562 cells after 72 hrs by MTT assay
Antiproliferative activity against human K562 cells after 72 hrs by MTT assay
|
[PMID: 30344902]
|
K562
|
IC50 |
0.021 μM
Compound: CA-4; 2
|
Antiproliferative activity against human K562 cells after 72 hrs by MTT assay
Antiproliferative activity against human K562 cells after 72 hrs by MTT assay
|
[PMID: 30176537]
|
K562
|
IC50 |
0.0282 nM
Compound: 7; CA-4
|
Cytotoxicity against human K562 cells assessed as reduction in cell viability incubated for 72 hrs by MTS assay
Cytotoxicity against human K562 cells assessed as reduction in cell viability incubated for 72 hrs by MTS assay
|
[PMID: 31401010]
|
K562
|
GI50 |
0.031 μM
Compound: 1; CA-4
|
Antiproliferative activity against human K562 cells assessed as cell growth inhibition measured after 48 hrs by SRB assay
Antiproliferative activity against human K562 cells assessed as cell growth inhibition measured after 48 hrs by SRB assay
|
[PMID: 27161282]
|
K562
|
IC50 |
|
Cytotoxicity against human K562 cells after 48 hrs by MTT assay
Cytotoxicity against human K562 cells after 48 hrs by MTT assay
|
[PMID: 19665898]
|
K562
|
IC50 |
|
Antiproliferative activity against human K562 cells incubated for 48 hrs by MTT assay
Antiproliferative activity against human K562 cells incubated for 48 hrs by MTT assay
|
[PMID: 32035399]
|
K562
|
IC50 |
|
Cytotoxicity against human K562 cells assessed as growth inhibition after 5 days by MTT assay
Cytotoxicity against human K562 cells assessed as growth inhibition after 5 days by MTT assay
|
[PMID: 28143677]
|
K562
|
IC50 |
|
Inhibition of tubulin polymerization in human K562 cells by fluorometric analysis
Inhibition of tubulin polymerization in human K562 cells by fluorometric analysis
|
[PMID: 21342735]
|
K562
|
IC50 |
|
Antiproliferative activity against human K562 cells measured after 72 hrs by MTT assay
Antiproliferative activity against human K562 cells measured after 72 hrs by MTT assay
|
[PMID: 36471625]
|
K562
|
IC50 |
|
Antiproliferative activity against human K562 cells by MTT assay
Antiproliferative activity against human K562 cells by MTT assay
|
[PMID: 23010271]
|
K562
|
GI50 |
|
Growth inhibition of human K562 cells after 48 hrs by sulforhodamine B assay
Growth inhibition of human K562 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 24388833]
|
K562
|
IC50 |
|
Antiproliferative activity against imatinib-resistant human K562 cells over expressing MDR1 after 72 hrs by CellTiter Glo assay
Antiproliferative activity against imatinib-resistant human K562 cells over expressing MDR1 after 72 hrs by CellTiter Glo assay
|
[PMID: 35797900]
|
K562
|
IC50 |
|
Antiproliferative activity against human K562 cells after 5 days by MTT assay
Antiproliferative activity against human K562 cells after 5 days by MTT assay
|
[PMID: 19837594]
|
K562
|
IC50 |
|
Cytotoxicity against human K562 cells after 72 hrs
Cytotoxicity against human K562 cells after 72 hrs
|
[PMID: 19530698]
|
K562
|
IC50 |
|
Cytotoxicity against human K562 cells after 48 hrs by SRB assay
Cytotoxicity against human K562 cells after 48 hrs by SRB assay
|
[PMID: 30784885]
|
K562
|
GI50 |
|
Cytotoxicity against human K562 cells assessed as growth inhibition after 48 hrs by SRB assay
Cytotoxicity against human K562 cells assessed as growth inhibition after 48 hrs by SRB assay
|
[PMID: 27707624]
|
K562
|
GI50 |
|
Cytotoxicity against human K562 cells after 72 hrs using resazurin dye by microtiter plate fluorimeter analysis
Cytotoxicity against human K562 cells after 72 hrs using resazurin dye by microtiter plate fluorimeter analysis
|
[PMID: 22449653]
|
K562
|
GI50 |
|
Cytotoxicity against human K562 cells after 72 hrs by CellTitre-Blue assay
Cytotoxicity against human K562 cells after 72 hrs by CellTitre-Blue assay
|
[PMID: 25528337]
|
K562
|
IC50 |
|
Cytotoxicity against human K562 cells after 48 hrs by MTT assay
Cytotoxicity against human K562 cells after 48 hrs by MTT assay
|
[PMID: 23356786]
|
K562
|
IC50 |
|
Antiproliferative activity against human K562 cells after 72 hrs by MTS assay
Antiproliferative activity against human K562 cells after 72 hrs by MTS assay
|
[PMID: 30525602]
|
K562
|
IC50 |
|
Antiproliferative activity against human K562 cells assessed as growth inhibition after 72 hrs by MTT assay
Antiproliferative activity against human K562 cells assessed as growth inhibition after 72 hrs by MTT assay
|
[PMID: 21663319]
|
K562
|
IC50 |
|
Antiproliferative activity against human K562 cells after 72 hrs by MTT assay
Antiproliferative activity against human K562 cells after 72 hrs by MTT assay
|
[PMID: 20420439]
|
K562
|
IC50 |
|
Antiproliferative activity against human K562 cells after 72 hrs by CellTiter Glo assay
Antiproliferative activity against human K562 cells after 72 hrs by CellTiter Glo assay
|
[PMID: 35797900]
|
K562
|
IC50 |
|
Antiproliferative activity against human K562 cells assessed as cell viability after 24 hrs by Celltiter-Glo assay
Antiproliferative activity against human K562 cells assessed as cell viability after 24 hrs by Celltiter-Glo assay
|
[PMID: 33038796]
|
K562
|
IC50 |
|
Antiproliferative activity against human K562 cells after 72 hrs by resazurin-based fluorescence assay
Antiproliferative activity against human K562 cells after 72 hrs by resazurin-based fluorescence assay
|
[PMID: 29202409]
|
K562
|
IC50 |
|
Antiproliferative activity against drug resistant human K562 cells incubated for 48 hrs by MTT assay
Antiproliferative activity against drug resistant human K562 cells incubated for 48 hrs by MTT assay
|
[PMID: 32035399]
|
K562
|
IC50 |
|
Antiproliferative activity against human K562 cells assessed as cell growth inhibition by MTT assay
Antiproliferative activity against human K562 cells assessed as cell growth inhibition by MTT assay
|
[PMID: 33636303]
|
K562/VCR
|
IC50 |
0.057 μM
Compound: 1; CA-4
|
Antiproliferative activity against VCR resistant human K562/VCR cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
Antiproliferative activity against VCR resistant human K562/VCR cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
|
[PMID: 33676300]
|
K562/VCR
|
IC50 |
0.057 μM
Compound: 1; CA-4
|
Antiproliferative activity against human VCR-resistant K562/VCR cells after 72 hrs by MTT assay
Antiproliferative activity against human VCR-resistant K562/VCR cells after 72 hrs by MTT assay
|
[PMID: 30530194]
|
K-562R
|
IC50 |
|
Antiproliferative activity against human K562R cells after 72 hrs by resazurin-based fluorescence assay
Antiproliferative activity against human K562R cells after 72 hrs by resazurin-based fluorescence assay
|
[PMID: 29202409]
|
K-562R
|
IC50 |
|
Antiproliferative activity against human K562R cells assessed as cell viability after 24 hrs by Celltiter-Glo assay
Antiproliferative activity against human K562R cells assessed as cell viability after 24 hrs by Celltiter-Glo assay
|
[PMID: 33038796]
|
K-562R
|
IC50 |
|
Antiproliferative activity against human K562R cells after 72 hrs by MTS assay
Antiproliferative activity against human K562R cells after 72 hrs by MTS assay
|
[PMID: 30525602]
|
KB
|
IC50 |
|
Cytotoxicity against human KB cells after 72 hrs by MTT assay
Cytotoxicity against human KB cells after 72 hrs by MTT assay
|
[PMID: 17373779]
|
KB
|
GI50 |
|
Antiproliferative activity against human KB cells assessed as cell growth inhibition by SRB assay
Antiproliferative activity against human KB cells assessed as cell growth inhibition by SRB assay
|
[PMID: 26242242]
|
KB
|
IC50 |
|
Antiproliferative activity against human KB cells measured after 72 hrs by MTT assay
Antiproliferative activity against human KB cells measured after 72 hrs by MTT assay
|
[PMID: 27428395]
|
KB
|
IC50 |
0.011 μM
Compound: 1; CA-4
|
Antiproliferative activity against human KB cells assessed as reduction in cell viability after 72 hrs by MTT assay
Antiproliferative activity against human KB cells assessed as reduction in cell viability after 72 hrs by MTT assay
|
[PMID: 30981112]
|
KB
|
IC50 |
0.011 μM
Compound: 1; CA-4
|
Antiproliferative activity against human KB cells after 72 hrs by MTT assay
Antiproliferative activity against human KB cells after 72 hrs by MTT assay
|
[PMID: 30530194]
|
KB
|
IC50 |
|
Antiproliferative activity against human KB cells after 72 hrs by MTT assay
Antiproliferative activity against human KB cells after 72 hrs by MTT assay
|
[PMID: 30525584]
|
KB
|
IC50 |
0.012 μM
Compound: CA-4; 1
|
Antiproliferative activity against human KB cells after 72 hrs by MTT assay
Antiproliferative activity against human KB cells after 72 hrs by MTT assay
|
[PMID: 30344902]
|
KB
|
IC50 |
0.013 μM
Compound: 1a, CA-4
|
Cytotoxicity against human KB cells assessed as cell growth inhibition after 72 hrs by MTT assay
Cytotoxicity against human KB cells assessed as cell growth inhibition after 72 hrs by MTT assay
|
[PMID: 25529737]
|
KB
|
IC50 |
0.013 μM
Compound: 1a, CA-4
|
Antiproliferative activity against human KB cells after 72 hrs by MTT assay
Antiproliferative activity against human KB cells after 72 hrs by MTT assay
|
[PMID: 25233100]
|
KB
|
IC50 |
0.016 μM
Compound: 1a; CA-4
|
Anti-proliferative activity against human KB cells after 72 hrs by MTT assay
Anti-proliferative activity against human KB cells after 72 hrs by MTT assay
|
10.1039/C5MD00028A
|
KB
|
IC50 |
0.25 μM
Compound: 1; CA-4
|
Antiproliferative activity against human KB cells measured after 72 hrs by MTT assay
Antiproliferative activity against human KB cells measured after 72 hrs by MTT assay
|
[PMID: 30901597]
|
KB
|
IC50 |
|
Antiproliferative activity against human KB cell line by methylene blue dye assay
Antiproliferative activity against human KB cell line by methylene blue dye assay
|
[PMID: 17034147]
|
KB
|
IC50 |
|
Growth inhibition of human KB cells after 72 hrs by methylene blue assay
Growth inhibition of human KB cells after 72 hrs by methylene blue assay
|
[PMID: 22060033]
|
KB
|
IC50 |
|
Antiproliferative activity against human KB cells after 72 hrs by methylene blue assay
Antiproliferative activity against human KB cells after 72 hrs by methylene blue assay
|
[PMID: 21641700]
|
KB
|
IC50 |
|
Growth inhibition of human KB cells after 72 hrs by methylene blue dye assay
Growth inhibition of human KB cells after 72 hrs by methylene blue dye assay
|
[PMID: 18588280]
|
KB
|
IC50 |
|
Antiproliferative activity against human KB cells after 72 hrs by methylene blue dye assay
Antiproliferative activity against human KB cells after 72 hrs by methylene blue dye assay
|
[PMID: 20148562]
|
KB
|
IC50 |
|
Antiproliferative activity against human KB cells after 72 hrs by methylene blue assay
Antiproliferative activity against human KB cells after 72 hrs by methylene blue assay
|
[PMID: 26160020]
|
KB
|
IC50 |
|
Cytotoxicity against human KB cells after 72 hrs by methylene blue assay
Cytotoxicity against human KB cells after 72 hrs by methylene blue assay
|
[PMID: 24657567]
|
KB
|
GI50 |
|
Antiproliferative activity against human KB cells assessed as cell growth inhibition measured after 72 hrs by SRB assay
Antiproliferative activity against human KB cells assessed as cell growth inhibition measured after 72 hrs by SRB assay
|
[PMID: 34917259]
|
KB
|
GI50 |
|
Antiproliferative activity against human KB cells assessed as reduction in cell viability incubated for 72 hrs by SRB assay
Antiproliferative activity against human KB cells assessed as reduction in cell viability incubated for 72 hrs by SRB assay
|
[PMID: 31938468]
|
KB
|
IC50 |
|
Cytotoxicity against vincristine-resistant human KB cells assessed as growth inhibition after 72 hrs by MTT assay
Cytotoxicity against vincristine-resistant human KB cells assessed as growth inhibition after 72 hrs by MTT assay
|
[PMID: 23981529]
|
KB
|
IC50 |
|
Inhibitory concentration against human oral cancer cell line (KB) using tetrazolium dye reduction assay (MTT)
Inhibitory concentration against human oral cancer cell line (KB) using tetrazolium dye reduction assay (MTT)
|
[PMID: 12467626]
|
KB
|
IC50 |
|
Inhibitory concentration against taxol resistant cell line (KBs5) at a concentration of 50 nM using tetrazolium dye reduction assay (MTT)
Inhibitory concentration against taxol resistant cell line (KBs5) at a concentration of 50 nM using tetrazolium dye reduction assay (MTT)
|
[PMID: 12467626]
|
KB
|
IC50 |
|
Inhibitory concentration against camptothecin (CPT) resistant cell line (KB-100) using tetrazolium dye reduction assay (MTT)
Inhibitory concentration against camptothecin (CPT) resistant cell line (KB-100) using tetrazolium dye reduction assay (MTT)
|
[PMID: 12467626]
|
KB
|
IC50 |
|
Inhibitory concentration against VP16 resistant cell line (KB-7D) using tetrazolium dye reduction assay (MTT)
Inhibitory concentration against VP16 resistant cell line (KB-7D) using tetrazolium dye reduction assay (MTT)
|
[PMID: 12467626]
|
KB
|
IC50 |
|
Cytotoxicity against human KB cells assessed as growth inhibition after 72 hrs by MTT assay
Cytotoxicity against human KB cells assessed as growth inhibition after 72 hrs by MTT assay
|
[PMID: 23981529]
|
KB
|
IC50 |
|
Inhibitory concentration against vincristine-resistant cell line (KB-Vin 10) using tetrazolium dye reduction assay (MTT)
Inhibitory concentration against vincristine-resistant cell line (KB-Vin 10) using tetrazolium dye reduction assay (MTT)
|
[PMID: 12467626]
|
KB 3-1
|
IC50 |
|
Cytotoxicity against human KB3-1 cells after 68 hrs by MTT assay
Cytotoxicity against human KB3-1 cells after 68 hrs by MTT assay
|
[PMID: 32243160]
|
KB-V1
|
IC50 |
|
Cytotoxicity against multidrug resistant human KB-V1 cells assessed as inhibition of cell growth after 72 hrs by MTT assay
Cytotoxicity against multidrug resistant human KB-V1 cells assessed as inhibition of cell growth after 72 hrs by MTT assay
|
[PMID: 31958738]
|
KB-V1
|
IC50 |
|
Cytotoxicity against human vinblastine-resistant KBV1 cells after 72 hrs by MTT assay
Cytotoxicity against human vinblastine-resistant KBV1 cells after 72 hrs by MTT assay
|
[PMID: 20731355]
|
KM12
|
GI50 |
0.005 μM
Compound: CA4, NSC 613729
|
Growth inhibition of human KM12 cells after 48 hrs by SRB assay
Growth inhibition of human KM12 cells after 48 hrs by SRB assay
|
[PMID: 24387982]
|
KM12
|
GI50 |
0.005 μM
Compound: 2, combretastatin A-4, CA-4, NSC 613729
|
Growth inhibition of human KM12 cells after 48 hrs by SRB assay
Growth inhibition of human KM12 cells after 48 hrs by SRB assay
|
[PMID: 22982122]
|
KM12
|
GI50 |
0.005 μM
Compound: CA4; NSC 613729
|
Cytotoxicity against human KM12 cells by SRB assay
Cytotoxicity against human KM12 cells by SRB assay
|
[PMID: 26257861]
|
KM12
|
GI50 |
|
Growth inhibition of human KM12 cells after 48 hrs by sulforhodamine B assay
Growth inhibition of human KM12 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 24388833]
|
KM-20L2
|
GI50 |
0.061 μg/mL
Compound: 1a, CA4
|
Growth inhibition of human KM20L2 cells after 48 hrs by sulforhodamine B assay
Growth inhibition of human KM20L2 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 22324723]
|
KM-20L2
|
GI50 |
0.061 μg/mL
Compound: 1a, CA4
|
Cytotoxicity against human KM20L2 cells after 48 hrs by sulforhodamine B assay
Cytotoxicity against human KM20L2 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 16252907]
|
KM-20L2
|
GI50 |
|
Growth inhibition of human KM20L2 cells after 48 hrs by sulforhodamine B assay
Growth inhibition of human KM20L2 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 19719153]
|
KM-20L2
|
GI50 |
0.34 μg/mL
Compound: Z-1b
|
Cytotoxicity against human KM20L2 cells after 48 hrs by sulforhodamine B assay
Cytotoxicity against human KM20L2 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 19709889]
|
KM-20L2
|
GI50 |
0.34 μg/mL
Compound: 3, CA4
|
Antitumor activity against human KM20L2 cells by sulforhodamine B assay
Antitumor activity against human KM20L2 cells by sulforhodamine B assay
|
[PMID: 19228038]
|
KM-20L2
|
GI50 |
0.34 μM
Compound: CA4, combretastatin A4
|
Cytotoxicity against human KM20L2 cells after 48 hrs by SRB assay
Cytotoxicity against human KM20L2 cells after 48 hrs by SRB assay
|
[PMID: 18303849]
|
KYSE-150 cell line
|
IC50 |
|
Antiproliferative activity against human KYSE-150 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay
Antiproliferative activity against human KYSE-150 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay
|
[PMID: 32063430]
|
KYSE-450
|
IC50 |
|
Antiproliferative activity against human KYSE-450 cells assessed as inhibition of cell growth measured after 48 hrs by MTT assay
Antiproliferative activity against human KYSE-450 cells assessed as inhibition of cell growth measured after 48 hrs by MTT assay
|
[PMID: 35834904]
|
L02
|
IC50 |
|
Antiproliferative activity against human L-O2 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
Antiproliferative activity against human L-O2 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
|
[PMID: 34428056]
|
L02
|
IC50 |
0.046 μM
Compound: 1; CA-4
|
Cytotoxicity against human L02 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
Cytotoxicity against human L02 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
|
[PMID: 33676300]
|
L02
|
IC50 |
0.046 μM
Compound: 1; CA-4
|
Antiproliferative activity against human LO2 cells after 72 hrs by MTT assay
Antiproliferative activity against human LO2 cells after 72 hrs by MTT assay
|
[PMID: 30530194]
|
L02
|
IC50 |
0.095 μM
Compound: 1; CA-4
|
Cytotoxicity against human LO2 cells assessed as reduction in cell viability after 72 hrs by MTT assay
Cytotoxicity against human LO2 cells assessed as reduction in cell viability after 72 hrs by MTT assay
|
[PMID: 30981112]
|
L02
|
IC50 |
|
Cytotoxicity against human LO2 cells after 72 hrs by MTT assay
Cytotoxicity against human LO2 cells after 72 hrs by MTT assay
|
[PMID: 30525584]
|
L02
|
IC50 |
0.095 μM
Compound: CA-4; 1
|
Cytotoxicity against human LO2 cells after 72 hrs by MTT assay
Cytotoxicity against human LO2 cells after 72 hrs by MTT assay
|
[PMID: 30344902]
|
L02
|
IC50 |
|
Antiproliferative activity against human L02 cells measured after 48 hrs by MTT assay
Antiproliferative activity against human L02 cells measured after 48 hrs by MTT assay
|
[PMID: 35551039]
|
L02
|
CC50 |
|
Antiproliferative activity against human LO2 cells incubated for 48 hrs by MTT assay
Antiproliferative activity against human LO2 cells incubated for 48 hrs by MTT assay
|
[PMID: 32035399]
|
L02
|
IC50 |
|
Cytotoxicity against human LO2 cells assessed as reduction in cell growth measured after 72 hrs by MTT assay
Cytotoxicity against human LO2 cells assessed as reduction in cell growth measured after 72 hrs by MTT assay
|
[PMID: 31830637]
|
L02
|
IC50 |
|
Cytotoxicity against human L02 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
Cytotoxicity against human L02 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
|
[PMID: 36252396]
|
L02
|
GI50 |
|
Cytotoxicity against human L02 cells assessed as assessed as cell growth inhibition measured after 72 hrs by MTT assay
Cytotoxicity against human L02 cells assessed as assessed as cell growth inhibition measured after 72 hrs by MTT assay
|
[PMID: 33201714]
|
L1210
|
IC50 |
0.002 μM
Compound: 1, CA-4
|
Cytotoxicity against mouse L1210 cells after 72 hrs by MTT assay
Cytotoxicity against mouse L1210 cells after 72 hrs by MTT assay
|
[PMID: 18226429]
|
L1210
|
IC50 |
0.003 μM
Compound: 1, CA-4
|
Antiproliferative activity against mouse L1210 cells after 2 days by coulter counter analysis
Antiproliferative activity against mouse L1210 cells after 2 days by coulter counter analysis
|
[PMID: 22027100]
|
L1210
|
IC50 |
0.003 μM
Compound: 2, CA-4
|
Cytotoxicity against mouse L1210 cells after 72 hrs by MTT assay
Cytotoxicity against mouse L1210 cells after 72 hrs by MTT assay
|
[PMID: 21524832]
|
L1210
|
IC50 |
|
Antiproliferative activity against mouse L1210 cells after 5 days by MTT assay
Antiproliferative activity against mouse L1210 cells after 5 days by MTT assay
|
[PMID: 19837594]
|
L1210
|
IC50 |
|
Antiproliferative activity against mouse L1210 cells after 2 days by coulter counting
Antiproliferative activity against mouse L1210 cells after 2 days by coulter counting
|
[PMID: 20579891]
|
L1210
|
IC50 |
|
Antiproliferative activity against mouse L1210 cells after 2 days by coulter counter method
Antiproliferative activity against mouse L1210 cells after 2 days by coulter counter method
|
[PMID: 19663386]
|
L1210
|
IC50 |
2.8 nM
Compound: 1a, CA-4
|
Cytotoxicity against mouse L1210 cells assessed as growth inhibition after 48 hrs by coulter counting analysis
Cytotoxicity against mouse L1210 cells assessed as growth inhibition after 48 hrs by coulter counting analysis
|
[PMID: 24164557]
|
L1210
|
IC50 |
|
Cytotoxicity against mouse L1210 cells after 2 days
Cytotoxicity against mouse L1210 cells after 2 days
|
[PMID: 19736015]
|
L1210
|
IC50 |
|
Antiproliferative activity against mouse L1210 cells after 2 days
Antiproliferative activity against mouse L1210 cells after 2 days
|
[PMID: 18755591]
|
L1210
|
IC50 |
|
Antiproliferative activity against mouse L1210 cells after 2 days by Coulter counter method
Antiproliferative activity against mouse L1210 cells after 2 days by Coulter counter method
|
[PMID: 29220790]
|
L132
|
IC50 |
|
Cytotoxicity against human L132 cells after 72 hrs by MTT assay
Cytotoxicity against human L132 cells after 72 hrs by MTT assay
|
[PMID: 17373779]
|
L929
|
IC50 |
0.82 μM
Compound: 2; CA-4
|
Antiproliferative activity against mouse L929 cells after 72 hrs by MTT assay
Antiproliferative activity against mouse L929 cells after 72 hrs by MTT assay
|
[PMID: 30245397]
|
LoVo
|
IC50 |
|
Antiproliferative activity against human LoVo cells measured after 48 hrs by MTT assay
Antiproliferative activity against human LoVo cells measured after 48 hrs by MTT assay
|
[PMID: 27721152]
|
LoVo
|
IC50 |
|
Antiproliferative activity against human LoVo cells after 48 hrs by MTT assay
Antiproliferative activity against human LoVo cells after 48 hrs by MTT assay
|
[PMID: 28792756]
|
LoVo
|
IC50 |
|
Antiproliferative activity against human LoVo after 48 hrs by spectrophotometry
Antiproliferative activity against human LoVo after 48 hrs by spectrophotometry
|
[PMID: 21774499]
|
LOX IMVI
|
GI50 |
0.003 μM
Compound: CA4, NSC 613729
|
Growth inhibition of human LOXIMVI cells after 48 hrs by SRB assay
Growth inhibition of human LOXIMVI cells after 48 hrs by SRB assay
|
[PMID: 24387982]
|
LOX IMVI
|
GI50 |
0.003 μM
Compound: 2, combretastatin A-4, CA-4, NSC 613729
|
Growth inhibition of human LOXIMVI cells after 48 hrs by SRB assay
Growth inhibition of human LOXIMVI cells after 48 hrs by SRB assay
|
[PMID: 22982122]
|
LOX IMVI
|
GI50 |
0.003 μM
Compound: CA4; NSC 613729
|
Cytotoxicity against human LOXIMVI cells by SRB assay
Cytotoxicity against human LOXIMVI cells by SRB assay
|
[PMID: 26257861]
|
LOX IMVI
|
GI50 |
|
Growth inhibition of human LOXIMVI cells after 48 hrs by sulforhodamine B assay
Growth inhibition of human LOXIMVI cells after 48 hrs by sulforhodamine B assay
|
[PMID: 24388833]
|
M14
|
GI50 |
0.002 μM
Compound: 2, combretastatin A-4, CA-4, NSC 613729
|
Growth inhibition of human M14 cells after 48 hrs by SRB assay
Growth inhibition of human M14 cells after 48 hrs by SRB assay
|
[PMID: 22982122]
|
M14
|
GI50 |
0.003 μM
Compound: CA4, NSC 613729
|
Growth inhibition of human M14 cells after 48 hrs by SRB assay
Growth inhibition of human M14 cells after 48 hrs by SRB assay
|
[PMID: 24387982]
|
M14
|
GI50 |
0.003 μM
Compound: CA4; NSC 613729
|
Cytotoxicity against human M14 cells by SRB assay
Cytotoxicity against human M14 cells by SRB assay
|
[PMID: 26257861]
|
M14
|
GI50 |
|
Growth inhibition of human M14 cells after 48 hrs by sulforhodamine B assay
Growth inhibition of human M14 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 24388833]
|
M21
|
IC50 |
|
Antiproliferative activity against human M21 cells assessed as inhibition of cell proliferation measured after 48 hrs by SRB assay
Antiproliferative activity against human M21 cells assessed as inhibition of cell proliferation measured after 48 hrs by SRB assay
|
[PMID: 34837817]
|
M21
|
IC50 |
|
Antiproliferative activity against human M21 cells assessed as cell growth inhibition after 48 hrs by sulforhodamine B assay
Antiproliferative activity against human M21 cells assessed as cell growth inhibition after 48 hrs by sulforhodamine B assay
|
[PMID: 26069928]
|
M21
|
IC50 |
|
Antiproliferative activity against human M21 cells assessed as reduction in cell viability measured after 48 hrs by sulforhodamine B assay
Antiproliferative activity against human M21 cells assessed as reduction in cell viability measured after 48 hrs by sulforhodamine B assay
|
[PMID: 33472119]
|
M21
|
IC50 |
|
Antiproliferative activity against human M21 cells after 48 hrs by SRB assay
Antiproliferative activity against human M21 cells after 48 hrs by SRB assay
|
[PMID: 21920638]
|
M21
|
IC50 |
|
Antiproliferative activity against human M21 cells after 48 hrs by sulforhodamine B assay
Antiproliferative activity against human M21 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 21604746]
|
Malme-3M
|
GI50 |
0.019 μM
Compound: 2, combretastatin A-4, CA-4, NSC 613729
|
Growth inhibition of human MALME-3M cells after 48 hrs by SRB assay
Growth inhibition of human MALME-3M cells after 48 hrs by SRB assay
|
[PMID: 22982122]
|
Malme-3M
|
GI50 |
0.02 μM
Compound: CA4, NSC 613729
|
Growth inhibition of human MALME-3M cells after 48 hrs by SRB assay
Growth inhibition of human MALME-3M cells after 48 hrs by SRB assay
|
[PMID: 24387982]
|
Malme-3M
|
GI50 |
|
Growth inhibition of human MALME-3M cells after 48 hrs by sulforhodamine B assay
Growth inhibition of human MALME-3M cells after 48 hrs by sulforhodamine B assay
|
[PMID: 24388833]
|
MC-38
|
IC50 |
|
Antiproliferative activity against mouse MC38 cells assessed as reduction in cell viability measured after 48 hrs by CCK8 assay
Antiproliferative activity against mouse MC38 cells assessed as reduction in cell viability measured after 48 hrs by CCK8 assay
|
[PMID: 33280898]
|
MCF-10A
|
GI50 |
< 1 x 10 -6 μM
Compound: CA-4
|
Growth inhibition of human MCF10A cells after 72 hrs by MTT assay
Growth inhibition of human MCF10A cells after 72 hrs by MTT assay
|
[PMID: 28284864]
|
MCF-10A
|
IC50 |
|
Cytotoxicity against human MCF10A cells assessed as reduction in cell viability after 96 hrs by MTT assay
Cytotoxicity against human MCF10A cells assessed as reduction in cell viability after 96 hrs by MTT assay
|
[PMID: 30935796]
|
MCF-10A
|
IC50 |
|
Antiproliferative activity against human MCF-10A cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
Antiproliferative activity against human MCF-10A cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
|
[PMID: 34428056]
|
MCF-10A
|
IC50 |
|
Antiproliferative activity against human MCF10A cells measured after 72 hrs by MTT assay
Antiproliferative activity against human MCF10A cells measured after 72 hrs by MTT assay
|
[PMID: 27187864]
|
MCF7
|
IC50 |
|
Antiproliferative activity against ER positive human MCF7 cells expressing low level of CYP assessed as reduction in cell viability measured after 96 hrs by MTT assay
Antiproliferative activity against ER positive human MCF7 cells expressing low level of CYP assessed as reduction in cell viability measured after 96 hrs by MTT assay
|
[PMID: 30935796]
|
MCF7
|
IC50 |
|
Antiproliferative activity against TCCD-induced ER positive human MCF7 cells expressing CYP1A1 assessed as reduction in cell viability after 96 hrs by MTT assay
Antiproliferative activity against TCCD-induced ER positive human MCF7 cells expressing CYP1A1 assessed as reduction in cell viability after 96 hrs by MTT assay
|
[PMID: 30935796]
|
MCF7
|
IC50 |
|
Antiproliferative activity against CYP1A1 expressing human MCF7 cells after 72 hrs by SRB assay
Antiproliferative activity against CYP1A1 expressing human MCF7 cells after 72 hrs by SRB assay
|
[PMID: 30201525]
|
MCF7
|
IC50 |
0.0024 μM
Compound: 1, CA4
|
Cytotoxicity against human MCF7 cells by MTT assay
Cytotoxicity against human MCF7 cells by MTT assay
|
[PMID: 19879758]
|
MCF7
|
IC50 |
0.0025 μM
Compound: Combretastatin A-4, IODWF
|
Antiproliferative activity against human MCF7 cells assessed as cell viability after 72 hrs by MTT assay
Antiproliferative activity against human MCF7 cells assessed as cell viability after 72 hrs by MTT assay
|
[PMID: 24012378]
|
MCF7
|
IC50 |
|
Antiproliferative activity against human MCF7 cells measured after 48 hrs by SRB assay
Antiproliferative activity against human MCF7 cells measured after 48 hrs by SRB assay
|
[PMID: 32113125]
|
MCF7
|
IC50 |
|
Antiproliferative activity against human MCF7/ADR cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
Antiproliferative activity against human MCF7/ADR cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
|
[PMID: 34428056]
|
MCF7
|
IC50 |
0.0031 μM
Compound: 2, CA-4
|
Antiproliferative activity against human MCF7 cells expressing estrogen receptor after 72 hrs by MTT assay
Antiproliferative activity against human MCF7 cells expressing estrogen receptor after 72 hrs by MTT assay
|
[PMID: 20933304]
|
MCF7
|
IC50 |
0.0035 μM
Compound: 2; CA-4
|
Antiproliferative activity against combretastatin A-4 resistant human MCF7 cells assessed as inhibition of cell growth incubated for 72 hrs by alamar blue assay
Antiproliferative activity against combretastatin A-4 resistant human MCF7 cells assessed as inhibition of cell growth incubated for 72 hrs by alamar blue assay
|
[PMID: 28254699]
|
MCF7
|
IC50 |
0.0039 μM
Compound: 2; CA-4
|
Antiproliferative activity against human MCF7 cells assessed as cell viability pre-incubated for 24 hrs with CO2 followed by compound addition after 72 hrs by MTT assay
Antiproliferative activity against human MCF7 cells assessed as cell viability pre-incubated for 24 hrs with CO2 followed by compound addition after 72 hrs by MTT assay
|
[PMID: 26680364]
|
MCF7
|
IC50 |
0.004 μM
Compound: CA-4; D-613729
|
Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability after 72 hrs by alamar blue assay
Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability after 72 hrs by alamar blue assay
|
[PMID: 31954879]
|
MCF7
|
IC50 |
0.004 μM
Compound: 1, CA-4
|
Cytotoxicity against human MCF7 cells after 3 days
Cytotoxicity against human MCF7 cells after 3 days
|
[PMID: 24139940]
|
MCF7
|
IC50 |
|
Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
|
[PMID: 34428056]
|
MCF7
|
IC50 |
0.005 μM
Compound: 4, CA-4
|
Antiproliferative activity against ER expressing human MCF7 cells after 72 hrs by MTT assay
Antiproliferative activity against ER expressing human MCF7 cells after 72 hrs by MTT assay
|
[PMID: 21840628]
|
MCF7
|
IC50 |
0.005 μM
Compound: 1; CA-4
|
Antiproliferative activity against human MCF7 assessed as reduction in cell viability measured after 48 hrs by SRB assay
Antiproliferative activity against human MCF7 assessed as reduction in cell viability measured after 48 hrs by SRB assay
|
[PMID: 27919655]
|
MCF7
|
GI50 |
0.005 μM
Compound: 2, combretastatin A-4, CA-4, NSC 613729
|
Growth inhibition of human MCF7 cells after 48 hrs by SRB assay
Growth inhibition of human MCF7 cells after 48 hrs by SRB assay
|
[PMID: 22982122]
|
MCF7
|
IC50 |
|
Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay
Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay
|
[PMID: 21080725]
|
MCF7
|
IC50 |
|
Cytotoxicity against human MCF7 cells after 96 hrs by sulforhodamine B assay
Cytotoxicity against human MCF7 cells after 96 hrs by sulforhodamine B assay
|
[PMID: 23810282]
|
MCF7
|
IC50 |
|
Cytotoxicity against human MCF7 cells assessed as reduction in cell viability measured after 24 hrs by MTT assay
Cytotoxicity against human MCF7 cells assessed as reduction in cell viability measured after 24 hrs by MTT assay
|
[PMID: 35447432]
|
MCF7
|
IC50 |
|
Anticancer activity against human MCF7 cells assessed as inhibition of cell growth incubated for 24 hrs by MTT assay
Anticancer activity against human MCF7 cells assessed as inhibition of cell growth incubated for 24 hrs by MTT assay
|
[PMID: 32731188]
|
MCF7
|
IC50 |
|
Antiproliferative activity against human MCF7 assessed as reduction in cell viability measured after 48 hrs by MTT assay
Antiproliferative activity against human MCF7 assessed as reduction in cell viability measured after 48 hrs by MTT assay
|
[PMID: 34175541]
|
MCF7
|
IC50 |
0.011 μM
Compound: 8; CA-4
|
Antiproliferative activity against human MCF7 cells assessed as cell growth inhibition after 72 hrs by SRB assay
Antiproliferative activity against human MCF7 cells assessed as cell growth inhibition after 72 hrs by SRB assay
|
[PMID: 34454126]
|
MCF7
|
IC50 |
0.0125 μM
Compound: 3; CA-4
|
Growth inhibition of human MCF7 cells incubated for 72 hrs by MTT assay
Growth inhibition of human MCF7 cells incubated for 72 hrs by MTT assay
|
[PMID: 27172319]
|
MCF7
|
IC50 |
|
Cytotoxicity against human MCF7 cells assessed as cell viability after 48 hrs by MTT assay
Cytotoxicity against human MCF7 cells assessed as cell viability after 48 hrs by MTT assay
|
[PMID: 27149641]
|
MCF7
|
IC50 |
|
Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay
Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay
|
[PMID: 21036623]
|
MCF7
|
IC50 |
|
Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay
Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay
|
[PMID: 20493717]
|
MCF7
|
GI50 |
|
Growth inhibition of human MCF7 cells after 3 days by MTT assay
Growth inhibition of human MCF7 cells after 3 days by MTT assay
|
[PMID: 27031215]
|
MCF7
|
IC50 |
|
Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability measured after 48 hrs by MTT assay
Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability measured after 48 hrs by MTT assay
|
[PMID: 34455231]
|
MCF7
|
GI50 |
|
Cytotoxicity against human MCF7 cells assessed as reduction in cell growth after 48 hrs by SRB assay
Cytotoxicity against human MCF7 cells assessed as reduction in cell growth after 48 hrs by SRB assay
|
[PMID: 27040661]
|
MCF7
|
GI50 |
|
Growth inhibition of MCF7 cells after 48 hrs
Growth inhibition of MCF7 cells after 48 hrs
|
[PMID: 17360188]
|
MCF7
|
IC50 |
|
Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
|
[PMID: 34649064]
|
MCF7
|
IC50 |
|
Antiproliferative activity against human MCF7 cells measured after 48 hrs by MTT assay
Antiproliferative activity against human MCF7 cells measured after 48 hrs by MTT assay
|
[PMID: 27721152]
|
MCF7
|
IC50 |
|
Cytotoxicity against human MCF7 cells assessed as growth inhibition after 72 hrs by MTT assay
Cytotoxicity against human MCF7 cells assessed as growth inhibition after 72 hrs by MTT assay
|
[PMID: 23708012]
|
MCF7
|
IC50 |
|
Anticancer activity against human MCF7 cells after 72 hrs
Anticancer activity against human MCF7 cells after 72 hrs
|
[PMID: 19713108]
|
MCF7
|
IC50 |
|
Antiproliferative activity against human MCF7 cells after 24 hrs by SRB assay
Antiproliferative activity against human MCF7 cells after 24 hrs by SRB assay
|
[PMID: 20006519]
|
MCF7
|
IC50 |
0.032 μM
Compound: Combretastatin A-4
|
Antiproliferative activity against human MCF7 cells assessed as inhibition of cell growth incubated for 48 hrs by SRB assay
Antiproliferative activity against human MCF7 cells assessed as inhibition of cell growth incubated for 48 hrs by SRB assay
|
[PMID: 32302879]
|
MCF7
|
GI50 |
0.033 μM
Compound: 1; CA-4
|
Antiproliferative activity against human MCF7 cells assessed as cell growth inhibition measured after 48 hrs by SRB assay
Antiproliferative activity against human MCF7 cells assessed as cell growth inhibition measured after 48 hrs by SRB assay
|
[PMID: 27161282]
|
MCF7
|
IC50 |
0.034 μM
Compound: 1; CA-4
|
Antiproliferative activity against human MCF7 cells assessed as reduction in cell growth incubated for 72 hrs by MTT assay
Antiproliferative activity against human MCF7 cells assessed as reduction in cell growth incubated for 72 hrs by MTT assay
|
[PMID: 33421913]
|
MCF7
|
IC50 |
|
Cytotoxicity against human MCF7 cells assessed as reduction in cell viability by MTT assay
Cytotoxicity against human MCF7 cells assessed as reduction in cell viability by MTT assay
|
[PMID: 33010448]
|
MCF7
|
IC50 |
|
Antiproliferative activity against human MCF7 cells assessed as reduction in cell growth after 48 hrs by MTT assay
Antiproliferative activity against human MCF7 cells assessed as reduction in cell growth after 48 hrs by MTT assay
|
[PMID: 33022479]
|
MCF7
|
IC50 |
0.041 μM
Compound: 1; CA4
|
Antiproliferative activity against human MCF7 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay
Antiproliferative activity against human MCF7 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay
|
[PMID: 32063430]
|
MCF7
|
IC50 |
|
Cytotoxicity against human MCF7 cells assessed as inhibition of cell growth after 48 hrs by MTT assay
Cytotoxicity against human MCF7 cells assessed as inhibition of cell growth after 48 hrs by MTT assay
|
[PMID: 30448234]
|
MCF7
|
IC50 |
|
Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay
Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay
|
[PMID: 28410492]
|
MCF7
|
IC50 |
|
Cytotoxicity against human MCF7 cells assessed as cell viability after 72 hrs by resazurin reduction assay
Cytotoxicity against human MCF7 cells assessed as cell viability after 72 hrs by resazurin reduction assay
|
[PMID: 26599530]
|
MCF7
|
IC50 |
0.043 μM
Compound: 2A; CA-4
|
Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay
Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay
|
[PMID: 28034647]
|
MCF7
|
IC50 |
0.046 μM
Compound: 1; CA-4
|
Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay
Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay
|
[PMID: 26970659]
|
MCF7
|
IC50 |
|
Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay
Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay
|
[PMID: 25192811]
|
MCF7
|
IC50 |
|
Cytotoxicity against human MCF7 cells after 68 hrs by MTT assay
Cytotoxicity against human MCF7 cells after 68 hrs by MTT assay
|
[PMID: 32243160]
|
MCF7
|
IC50 |
|
Cytotoxicity against human MCF7 cells assessed as growth inhibition after 48 hrs by MTT assay
Cytotoxicity against human MCF7 cells assessed as growth inhibition after 48 hrs by MTT assay
|
[PMID: 23809851]
|
MCF7
|
IC50 |
|
Antiproliferative activity against human MCF7 cells measured after 48 hrs by MTT assay
Antiproliferative activity against human MCF7 cells measured after 48 hrs by MTT assay
|
[PMID: 35551039]
|
MCF7
|
IC50 |
|
Cytotoxicity against human MCF7 cells assessed as growth inhibition after 48 hrs by MTT assay
Cytotoxicity against human MCF7 cells assessed as growth inhibition after 48 hrs by MTT assay
|
[PMID: 28803046]
|
MCF7
|
IC50 |
0.134 μM
Compound: 2a; CA-4
|
Cytotoxicity against human MCF7 cells assessed as cell viability after 48 hrs by SRB assay
Cytotoxicity against human MCF7 cells assessed as cell viability after 48 hrs by SRB assay
|
10.1039/C5MD00155B
|
MCF7
|
IC50 |
0.14 μM
Compound: 6a; CA-4
|
Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability after 24 hrs by CCK-8 assay
Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability after 24 hrs by CCK-8 assay
|
[PMID: 34458740]
|
MCF7
|
GI50 |
|
Growth inhibition of human MCF7 cells after 48 hrs by MTT assay
Growth inhibition of human MCF7 cells after 48 hrs by MTT assay
|
[PMID: 30041136]
|
MCF7
|
IC50 |
|
Antiproliferative activity against human MCF7 cells measured after 48 hrs by MTT assay
Antiproliferative activity against human MCF7 cells measured after 48 hrs by MTT assay
|
[PMID: 32717486]
|
MCF7
|
IC50 |
0.17 μM
Compound: 1a; CA-4
|
Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay
Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay
|
[PMID: 29291446]
|
MCF7
|
IC50 |
|
Antiproliferative activity against human MCF7 cells after 24 hrs by MTT assay
Antiproliferative activity against human MCF7 cells after 24 hrs by MTT assay
|
[PMID: 30606674]
|
MCF7
|
IC50 |
0.18 μM
Compound: Combretastatin A-4
|
Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay
Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay
|
[PMID: 30108703]
|
MCF7
|
IC50 |
0.18 μM
Compound: Combretastatin-A4
|
Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay
Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay
|
[PMID: 27487568]
|
MCF7
|
IC50 |
0.18 μM
Compound: 2a, CA-4
|
Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay
Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay
|
[PMID: 22543234]
|
MCF7
|
IC50 |
|
Cytotoxicity against human MCF7 cells after 72 hrs by MTS/PMS assay
Cytotoxicity against human MCF7 cells after 72 hrs by MTS/PMS assay
|
[PMID: 30230828]
|
MCF7
|
IC50 |
0.21 μg/mL
Compound: 2, CA-4
|
Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay
Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay
|
[PMID: 24916028]
|
MCF7
|
IC50 |
|
Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay
Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay
|
[PMID: 25703297]
|
MCF7
|
IC50 |
|
Antiproliferative activity against human MCF7 cells incubated for 48 hrs by MTT assay
Antiproliferative activity against human MCF7 cells incubated for 48 hrs by MTT assay
|
[PMID: 32035399]
|
MCF7
|
IC50 |
|
Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability after 24 hrs by MTT assay
Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability after 24 hrs by MTT assay
|
[PMID: 25828827]
|
MCF7
|
IC50 |
|
Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay
Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay
|
[PMID: 24909678]
|
MCF7
|
IC50 |
|
Antiproliferative activity against human MCF7 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay
Antiproliferative activity against human MCF7 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay
|
[PMID: 31536891]
|
MCF7
|
IC50 |
|
Cytotoxicity against human MCF7 cells assessed as growth inhibition after 48 hrs by MTT assay
Cytotoxicity against human MCF7 cells assessed as growth inhibition after 48 hrs by MTT assay
|
[PMID: 23566762]
|
MCF7
|
IC50 |
0.41 μg/mL
Compound: CA-4
|
Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay
Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay
|
[PMID: 22261027]
|
MCF7
|
IC50 |
|
Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay
Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay
|
[PMID: 22512906]
|
MCF7
|
IC50 |
|
Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay
Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay
|
[PMID: 34311158]
|
MCF7
|
IC50 |
0.43 μg/mL
Compound: CA-4
|
Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay
Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay
|
[PMID: 22503741]
|
MCF7
|
IC50 |
|
Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
|
[PMID: 36252396]
|
MCF7
|
IC50 |
0.48 μg/mL
Compound: CA-4
|
Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay
Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay
|
[PMID: 22192936]
|
MCF7
|
IC50 |
|
Antiproliferative activity against drug-resistant human MCF7 cells incubated for 48 hrs by MTT assay
Antiproliferative activity against drug-resistant human MCF7 cells incubated for 48 hrs by MTT assay
|
[PMID: 32035399]
|
MCF7
|
IC50 |
|
Antiproliferative activity against human MCF7 cells after 72 hrs by CCK-8 assay
Antiproliferative activity against human MCF7 cells after 72 hrs by CCK-8 assay
|
[PMID: 30108925]
|
MCF7
|
IC50 |
|
Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay
Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay
|
[PMID: 24238904]
|
MCF7
|
IC50 |
|
Cytotoxicity against human MCF7 cells assessed as growth inhibition after 3 days by MTT assay
Cytotoxicity against human MCF7 cells assessed as growth inhibition after 3 days by MTT assay
|
[PMID: 24145138]
|
MCF7
|
IC50 |
|
Cytotoxicity against human MCF7 cells assessed as inhibition of cell growth after 72 hrs by MTT assay
Cytotoxicity against human MCF7 cells assessed as inhibition of cell growth after 72 hrs by MTT assay
|
[PMID: 25240870]
|
MCF7
|
IC50 |
|
Antiproliferative activity against human MCF7 cells by MTT assay
Antiproliferative activity against human MCF7 cells by MTT assay
|
[PMID: 30502686]
|
MCF7
|
IC50 |
|
Antiproliferative activity against human MCF7 cells incubated for 48 hrs by MTS assay
Antiproliferative activity against human MCF7 cells incubated for 48 hrs by MTS assay
|
[PMID: 31541870]
|
MCF7
|
IC50 |
|
Antiproliferative activity in human MCF7 cells assessed as cell viability after 72 hrs by MTT assay
Antiproliferative activity in human MCF7 cells assessed as cell viability after 72 hrs by MTT assay
|
[PMID: 22329561]
|
MCF7
|
IC50 |
|
Antiproliferative activity against human MCF7 cells assessed as cell viability after 48 hrs by MTT assay
Antiproliferative activity against human MCF7 cells assessed as cell viability after 48 hrs by MTT assay
|
[PMID: 26974371]
|
MCF7
|
IC50 |
|
Inhibition of tubulin polymerization in human MCF7 cells by fluorometric analysis
Inhibition of tubulin polymerization in human MCF7 cells by fluorometric analysis
|
[PMID: 21342735]
|
MCF7
|
IC50 |
|
Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability measured after 48 hrs by sulforhodamine B assay
Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability measured after 48 hrs by sulforhodamine B assay
|
[PMID: 33472119]
|
MCF7
|
IC50 |
|
Antiproliferative activity against human MCF7 cells after 2 days by MTT assay
Antiproliferative activity against human MCF7 cells after 2 days by MTT assay
|
[PMID: 29432949]
|
MCF7
|
IC50 |
|
Antiproliferative activity against human MCF7 cells assessed after 48 hrs by spectrophotometry
Antiproliferative activity against human MCF7 cells assessed after 48 hrs by spectrophotometry
|
[PMID: 21774499]
|
MCF7
|
IC50 |
|
Growth inhibition of human MCF7 after 48 hrs by sulforhodamine B method
Growth inhibition of human MCF7 after 48 hrs by sulforhodamine B method
|
[PMID: 16124759]
|
MCF7
|
IC50 |
|
Cytotoxicity was determined by inhibition of cell growth of MCF-7 human breast carcinoma cell
Cytotoxicity was determined by inhibition of cell growth of MCF-7 human breast carcinoma cell
|
[PMID: 11527727]
|
MCF7
|
IC50 |
|
Antiproliferative activity against human MCF7 cells after 72 hrs
Antiproliferative activity against human MCF7 cells after 72 hrs
|
[PMID: 17034133]
|
MCF7
|
IC50 |
|
Cytotoxicity against human MCF7 cells assessed as growth inhibition after 48 hrs by SRB assay
Cytotoxicity against human MCF7 cells assessed as growth inhibition after 48 hrs by SRB assay
|
[PMID: 26132075]
|
MCF7
|
IC50 |
|
Cytotoxicity against human MCF7 cells assessed as cell growth inhibition incubated for 3 days by trypan blue exclusion assay
Cytotoxicity against human MCF7 cells assessed as cell growth inhibition incubated for 3 days by trypan blue exclusion assay
|
[PMID: 28523104]
|
MCF7
|
IC50 |
|
Cytotoxicity against human MCF7 cells assessed as growth inhibition by trypan blue exclusion assay
Cytotoxicity against human MCF7 cells assessed as growth inhibition by trypan blue exclusion assay
|
[PMID: 23214452]
|
MCF7
|
IC50 |
|
Cytotoxicity against human MCF7 cells after 96 hrs by Giemsa staining-based light microscopy
Cytotoxicity against human MCF7 cells after 96 hrs by Giemsa staining-based light microscopy
|
[PMID: 25025991]
|
MCF7
|
IC50 |
|
Growth inhibition of human MCF7 cells after 96 hrs
Growth inhibition of human MCF7 cells after 96 hrs
|
[PMID: 22044164]
|
MCF7
|
IC50 |
|
Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay
Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay
|
[PMID: 28792756]
|
MCF7
|
IC50 |
|
Growth inhibition of human MCF7 cells after 48 hrs
Growth inhibition of human MCF7 cells after 48 hrs
|
[PMID: 17497841]
|
MCF7
|
IC50 |
17 nM
Compound: 6, combretastatin A-4
|
Growth inhibition of human MCF7 cells assessed as G2/M DNA content after 48 hrs
Growth inhibition of human MCF7 cells assessed as G2/M DNA content after 48 hrs
|
[PMID: 15566282]
|
MCF7
|
IC50 |
|
Antiproliferative activity against human MCF7 cells assessed as cell growth inhibition by MTT assay
Antiproliferative activity against human MCF7 cells assessed as cell growth inhibition by MTT assay
|
[PMID: 33636303]
|
MCF7
|
IC50 |
|
Antiproliferative activity against human MCF7 cells after 72 hrs by CellTiter Glo assay
Antiproliferative activity against human MCF7 cells after 72 hrs by CellTiter Glo assay
|
[PMID: 35797900]
|
MCF7
|
IC50 |
|
Antiproliferative activity against human MCF7 cells incubated for 48 hrs by sulforhodamine B assay
Antiproliferative activity against human MCF7 cells incubated for 48 hrs by sulforhodamine B assay
|
[PMID: 26938120]
|
MCF7
|
IC50 |
|
Antiproliferative activity against human MCF7 cells assessed as cell growth inhibition after 48 hrs by sulforhodamine B assay
Antiproliferative activity against human MCF7 cells assessed as cell growth inhibition after 48 hrs by sulforhodamine B assay
|
[PMID: 26069928]
|
MCF7
|
IC50 |
|
Growth inhibition of human MCF7 cells after 48 hrs by sulforhodamine B assay
Growth inhibition of human MCF7 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 19601594]
|
MCF7
|
IC50 |
|
Inhibition of tubulin polymerization in human MCF7 cells assessed as suppression of protein assembly after 15 mins by spectrophotometric analysis
Inhibition of tubulin polymerization in human MCF7 cells assessed as suppression of protein assembly after 15 mins by spectrophotometric analysis
|
[PMID: 27994737]
|
MCF7
|
IC50 |
|
Cytotoxicity against human MCF7 cells assessed as growth inhibition after 72 hrs by MTT assay
Cytotoxicity against human MCF7 cells assessed as growth inhibition after 72 hrs by MTT assay
|
[PMID: 23981529]
|
MCF7
|
IC50 |
25 nM
Compound: combretastatin A-4
|
Cell growth inhibition against MCF-7 human breast cancer cells using MTS assay
Cell growth inhibition against MCF-7 human breast cancer cells using MTS assay
|
[PMID: 12036364]
|
MCF7
|
IC50 |
|
Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay
Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay
|
10.1039/C3MD00372H
|
MCF7
|
IC50 |
|
Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay
Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay
|
[PMID: 30472600]
|
MCF7
|
IC50 |
|
Growth inhibition of human MCF7 cells after 48 hrs by SRB assay
Growth inhibition of human MCF7 cells after 48 hrs by SRB assay
|
[PMID: 24900453]
|
MCF7
|
IC50 |
3.45 μM
Compound: Combretastatin A-4
|
Antiproliferative activity against human MCF7 cells incubated for 24 hrs by MTT assay
Antiproliferative activity against human MCF7 cells incubated for 24 hrs by MTT assay
|
[PMID: 32992133]
|
MCF7
|
IC50 |
370 nM
Compound: 1a; CA-4
|
Antiproliferative activity against human MCF7 cells assessed as inhibition of cell proliferation incubated for 72 hrs by MTT assay
Antiproliferative activity against human MCF7 cells assessed as inhibition of cell proliferation incubated for 72 hrs by MTT assay
|
[PMID: 31400707]
|
MCF7
|
IC50 |
370 nM
Compound: 1a, CA-4
|
Growth inhibition of human MCF7 cells after 72 hrs by MTT assay
Growth inhibition of human MCF7 cells after 72 hrs by MTT assay
|
[PMID: 25025853]
|
MCF7
|
IC50 |
|
Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay
Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay
|
[PMID: 23445496]
|
MCF7
|
IC50 |
370 nM
Compound: CA-4, 1a, 1
|
Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay
Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay
|
[PMID: 23117171]
|
MCF7
|
IC50 |
|
Antiproliferative activity against human MCF7 cells assessed as growth inhibition after 72 hrs by MTT assay
Antiproliferative activity against human MCF7 cells assessed as growth inhibition after 72 hrs by MTT assay
|
[PMID: 22578111]
|
MCF7
|
IC50 |
|
Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay
Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay
|
[PMID: 22136312]
|
MCF7
|
IC50 |
|
Antiproliferative activity against human MCF7 cells assessed as growth inhibition after 72 hrs by MTT assay
Antiproliferative activity against human MCF7 cells assessed as growth inhibition after 72 hrs by MTT assay
|
[PMID: 21663319]
|
MCF7
|
IC50 |
|
Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay
Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay
|
[PMID: 20420439]
|
MCF7
|
IC50 |
370 nM
Compound: 1a, CA-4
|
Antiproliferative activity against human MCF7 cells after 72 hrs by (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide test
Antiproliferative activity against human MCF7 cells after 72 hrs by (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide test
|
[PMID: 25785605]
|
MCF7
|
IC50 |
|
Antiproliferative activity against human MCF7 cells after 72 hrs by CCK8 assay
Antiproliferative activity against human MCF7 cells after 72 hrs by CCK8 assay
|
[PMID: 30006162]
|
MCF7
|
GI50 |
39.8 nM
Compound: 1, CA-4
|
Cytotoxicity against human MCF7 cells after 48 hrs by sulforhodamine B assay
Cytotoxicity against human MCF7 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 21920767]
|
MCF7
|
IC50 |
|
Antiproliferative activity against human MCF7 cells after 48 hrs by sulforhodamine B assay
Antiproliferative activity against human MCF7 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 28684120]
|
MCF7
|
IC50 |
4.63 μM
Compound: Combretastatin
|
Antiproliferative activity in human MCF7 cells assessed as reduction in cell number incubated for 48 hrs by SRB assay
Antiproliferative activity in human MCF7 cells assessed as reduction in cell number incubated for 48 hrs by SRB assay
|
[PMID: 30108756]
|
MCF7
|
IC50 |
|
Antiproliferative activity against human MCF7 cells assessed as cell growth inhibition measured after 72 hrs by MTT assay
Antiproliferative activity against human MCF7 cells assessed as cell growth inhibition measured after 72 hrs by MTT assay
|
[PMID: 34826681]
|
MCF7
|
IC50 |
48.9 μM
Compound: 2, CA-4
|
Cytotoxicity against human MCF7 cells by alamar blue assay
Cytotoxicity against human MCF7 cells by alamar blue assay
|
[PMID: 22137934]
|
MCF7
|
IC50 |
|
Antiproliferative activity against human MCF7 cells assessed as inhibition of cell growth after 72 hrs by MTT assay
Antiproliferative activity against human MCF7 cells assessed as inhibition of cell growth after 72 hrs by MTT assay
|
[PMID: 23454513]
|
MCF7
|
IC50 |
|
Growth inhibition of human MCF7 cells after 96 hrs by trypan blue exclusion assay
Growth inhibition of human MCF7 cells after 96 hrs by trypan blue exclusion assay
|
[PMID: 29730191]
|
MCF7
|
IC50 |
|
Antiproliferative activity against human MCF7 cells after 48 hrs by SRB assay
Antiproliferative activity against human MCF7 cells after 48 hrs by SRB assay
|
[PMID: 21920638]
|
MCF7
|
IC50 |
|
Antiproliferative activity against human MCF7 cells after 48 hrs by sulforhodamine B assay
Antiproliferative activity against human MCF7 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 21604746]
|
MCF7
|
IC50 |
|
Antiproliferative activity against human MCF7 cells measured after 72 hrs by MTT assay
Antiproliferative activity against human MCF7 cells measured after 72 hrs by MTT assay
|
[PMID: 36471625]
|
MCF7
|
IC50 |
|
Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay
Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay
|
[PMID: 29396364]
|
MCF7
|
IC50 |
|
Antiproliferative activity against human MCF7 cells assessed as cell viability after 24 hrs by Celltiter-Glo assay
Antiproliferative activity against human MCF7 cells assessed as cell viability after 24 hrs by Celltiter-Glo assay
|
[PMID: 33038796]
|
MCF7
|
IC50 |
|
Antiproliferative activity against human MCF7 cells after 72 hrs by resazurin-based fluorescence assay
Antiproliferative activity against human MCF7 cells after 72 hrs by resazurin-based fluorescence assay
|
[PMID: 29202409]
|
MCF7
|
GI50 |
|
Antiproliferative activity against human MCF7 cells assessed as cell growth inhibition measured after 72 hrs by SRB assay
Antiproliferative activity against human MCF7 cells assessed as cell growth inhibition measured after 72 hrs by SRB assay
|
[PMID: 34917259]
|
MCF7
|
GI50 |
|
Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability incubated for 72 hrs by SRB assay
Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability incubated for 72 hrs by SRB assay
|
[PMID: 31938468]
|
MCF7
|
IC50 |
|
Darktoxicity against human MCF7 cells incubated for 24 hrs followed by 30 mins incubation in dark measured after 3 days by MTT assay
Darktoxicity against human MCF7 cells incubated for 24 hrs followed by 30 mins incubation in dark measured after 3 days by MTT assay
|
[PMID: 23631389]
|
MCF7
|
GI50 |
|
Growth inhibition of human MCF7 cells assessed as inhibition of cell proliferation after 24 hrs by MTT assay
Growth inhibition of human MCF7 cells assessed as inhibition of cell proliferation after 24 hrs by MTT assay
|
[PMID: 26070164]
|
MDA-MB-231
|
GI50 |
0.001 μM
Compound: 2, combretastatin A-4, CA-4, NSC 613729
|
Growth inhibition of human MDA-MB-231 cells after 48 hrs by SRB assay
Growth inhibition of human MDA-MB-231 cells after 48 hrs by SRB assay
|
[PMID: 22982122]
|
MDA-MB-231
|
IC50 |
|
Antiproliferative activity against human MDA-MB-231 cells by MTT assay
Antiproliferative activity against human MDA-MB-231 cells by MTT assay
|
[PMID: 29126741]
|
MDA-MB-231
|
IC50 |
|
Antiproliferative activity against CYP1A1 deficient human MDA-MB-231 cells after 72 hrs by SRB assay
Antiproliferative activity against CYP1A1 deficient human MDA-MB-231 cells after 72 hrs by SRB assay
|
[PMID: 30201525]
|
MDA-MB-231
|
IC50 |
|
Cytotoxicity against human MDA-MB-231 cells after 72 hrs by resazurin based fluorescence assay
Cytotoxicity against human MDA-MB-231 cells after 72 hrs by resazurin based fluorescence assay
|
[PMID: 24669888]
|
MDA-MB-231
|
GI50 |
0.002806 μM
Compound: CA-4
|
Growth inhibition of human MDA-MB-231 cells after 72 hrs by MTT assay
Growth inhibition of human MDA-MB-231 cells after 72 hrs by MTT assay
|
[PMID: 28284864]
|
MDA-MB-231
|
IC50 |
|
Antiproliferative activity against human MDA-MB-231 cells after 72 hrs by CCK8 assay
Antiproliferative activity against human MDA-MB-231 cells after 72 hrs by CCK8 assay
|
[PMID: 30006162]
|
MDA-MB-231
|
IC50 |
0.008 μM
Compound: 1; CA-4
|
Antiproliferative activity against human MDA-MB-231 cells after 48 hrs by MTT assay
Antiproliferative activity against human MDA-MB-231 cells after 48 hrs by MTT assay
|
[PMID: 29306206]
|
MDA-MB-231
|
IC50 |
0.01 μM
Compound: 1; CA-4
|
Antiproliferative activity against human MDA-MB-231 cells assessed as reduction in cell viability after 72 hrs by MTT assay
Antiproliferative activity against human MDA-MB-231 cells assessed as reduction in cell viability after 72 hrs by MTT assay
|
[PMID: 30981112]
|
MDA-MB-231
|
IC50 |
0.011 μM
Compound: 1; CA-4
|
Antiproliferative activity against human MDA-MB-231 cells after 72 hrs by MTT assay
Antiproliferative activity against human MDA-MB-231 cells after 72 hrs by MTT assay
|
[PMID: 30530194]
|
MDA-MB-231
|
IC50 |
0.012 μM
Compound: 1; CA-4
|
Antiproliferative activity against human MDA-MB-231 cells after 48 hrs by MTT assay
Antiproliferative activity against human MDA-MB-231 cells after 48 hrs by MTT assay
|
[PMID: 35065411]
|
MDA-MB-231
|
IC50 |
|
Cytotoxicity against human MDA-MB-231 cells assessed as reduction in cell viability measured after 24 hrs by MTT assay
Cytotoxicity against human MDA-MB-231 cells assessed as reduction in cell viability measured after 24 hrs by MTT assay
|
[PMID: 35447432]
|
MDA-MB-231
|
IC50 |
0.015 μM
Compound: 1; CA-4
|
Antiproliferative activity against human MDA-MB-231 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
Antiproliferative activity against human MDA-MB-231 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
|
[PMID: 33676300]
|
MDA-MB-231
|
IC50 |
|
Antiproliferative activity against human MDA-MB-231 cells after 72 hrs by MTT assay
Antiproliferative activity against human MDA-MB-231 cells after 72 hrs by MTT assay
|
[PMID: 30525584]
|
MDA-MB-231
|
IC50 |
0.015 μM
Compound: CA-4; 1
|
Antiproliferative activity against human MDA-MB-231 cells after 72 hrs by MTT assay
Antiproliferative activity against human MDA-MB-231 cells after 72 hrs by MTT assay
|
[PMID: 30344902]
|
MDA-MB-231
|
IC50 |
0.017 μM
Compound: 1; CA4
|
Antiproliferative activity against human MDA-MB-231 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay
Antiproliferative activity against human MDA-MB-231 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay
|
[PMID: 32063430]
|
MDA-MB-231
|
GI50 |
|
Antiproliferative activity against human MDA-MB-231 cells after 48 hrs by MTT assay
Antiproliferative activity against human MDA-MB-231 cells after 48 hrs by MTT assay
|
10.1039/C5MD00139K
|
MDA-MB-231
|
IC50 |
0.03 μM
Compound: Combretastatin A-4
|
Antiproliferative activity against human MDA-MB-231 cells assessed as reduction in cell proliferation after 3 days by 3H-thymidine incorporation assay
Antiproliferative activity against human MDA-MB-231 cells assessed as reduction in cell proliferation after 3 days by 3H-thymidine incorporation assay
|
[PMID: 27212068]
|
MDA-MB-231
|
IC50 |
0.043 μM
Compound: 4, CA-4
|
Antiproliferative activity against ER-independent human MDA-MB-231 cells after 72 hrs by MTT assay
Antiproliferative activity against ER-independent human MDA-MB-231 cells after 72 hrs by MTT assay
|
[PMID: 21840628]
|
MDA-MB-231
|
IC50 |
|
Antiproliferative activity against human MDA-MB-231 cells after 72 hrs by MTT assay
Antiproliferative activity against human MDA-MB-231 cells after 72 hrs by MTT assay
|
[PMID: 21080725]
|
MDA-MB-231
|
IC50 |
0.043 μM
Compound: 2, CA-4
|
Antiproliferative activity against estrogen receptor deficient human MDA-MB-231 cells after 72 hrs by MTT assay
Antiproliferative activity against estrogen receptor deficient human MDA-MB-231 cells after 72 hrs by MTT assay
|
[PMID: 20933304]
|
MDA-MB-231
|
GI50 |
|
Antiproliferative activity against human MDA-MB-231 cells after 48 hrs by MTT assay
Antiproliferative activity against human MDA-MB-231 cells after 48 hrs by MTT assay
|
[PMID: 29227648]
|
MDA-MB-231
|
GI50 |
0.046 μM
Compound: Combretastatin
|
Antiproliferative activity against human MDA-MB-231 cells after 48 hrs by SRB cell proliferation assay
Antiproliferative activity against human MDA-MB-231 cells after 48 hrs by SRB cell proliferation assay
|
[PMID: 29089233]
|
MDA-MB-231
|
IC50 |
|
Antiproliferative activity against human MDA-MB-231 cells incubated for 48 hrs by MTT assay
Antiproliferative activity against human MDA-MB-231 cells incubated for 48 hrs by MTT assay
|
[PMID: 32035399]
|
MDA-MB-231
|
IC50 |
|
Cytotoxicity against human MDA-MB-231 cells after 48 hrs by MTT assay
Cytotoxicity against human MDA-MB-231 cells after 48 hrs by MTT assay
|
10.1039/C2MD20085F
|
MDA-MB-231
|
IC50 |
|
Cytotoxicity against human MDA-MB-231 cells assessed as growth inhibition after 48 hrs by MTT assay
Cytotoxicity against human MDA-MB-231 cells assessed as growth inhibition after 48 hrs by MTT assay
|
[PMID: 28803046]
|
MDA-MB-231
|
IC50 |
0.56 μM
Compound: 1a; CA-4
|
Cytotoxicity against human MDA-MB-231 cells after 48 hrs by MTT assay
Cytotoxicity against human MDA-MB-231 cells after 48 hrs by MTT assay
|
[PMID: 29291446]
|
MDA-MB-231
|
IC50 |
0.92 μM
Compound: 1; CA-4
|
Antiproliferative activity against human MDA-MB-231 cells after 24 hrs by SRB assay
Antiproliferative activity against human MDA-MB-231 cells after 24 hrs by SRB assay
|
[PMID: 29268127]
|
MDA-MB-231
|
IC50 |
|
Antiproliferative activity against human MDA-MB-231 cells assessed as reduction in cell viability after 72 hrs by MTT assay
Antiproliferative activity against human MDA-MB-231 cells assessed as reduction in cell viability after 72 hrs by MTT assay
|
[PMID: 31610372]
|
MDA-MB-231
|
IC50 |
|
Antiproliferative activity against human MDA-MB-231 cells after 48 hrs by MTT assay
Antiproliferative activity against human MDA-MB-231 cells after 48 hrs by MTT assay
|
[PMID: 28410492]
|
MDA-MB-231
|
IC50 |
|
Antiproliferative activity against human MDA-MB-231 cells after 72 hrs by CellTiter Glo assay
Antiproliferative activity against human MDA-MB-231 cells after 72 hrs by CellTiter Glo assay
|
[PMID: 35797900]
|
MDA-MB-231
|
GI50 |
|
Cytotoxicity against human MDA-MB-231 cells after 72 hrs using resazurin dye by microtiter plate fluorimeter analysis
Cytotoxicity against human MDA-MB-231 cells after 72 hrs using resazurin dye by microtiter plate fluorimeter analysis
|
[PMID: 22449653]
|
MDA-MB-231
|
IC50 |
|
Cytotoxicity against human MDA-MB-231 cells after 72 hrs
Cytotoxicity against human MDA-MB-231 cells after 72 hrs
|
[PMID: 19530698]
|
MDA-MB-231
|
IC50 |
|
Cytotoxicity against human MDA-MB-231 cells after 72 hrs by MTT assay
Cytotoxicity against human MDA-MB-231 cells after 72 hrs by MTT assay
|
[PMID: 30472600]
|
MDA-MB-231
|
IC50 |
|
Antiproliferative activity against human MDA-MB-231 after 48 hrs by spectrophotometry
Antiproliferative activity against human MDA-MB-231 after 48 hrs by spectrophotometry
|
[PMID: 21774499]
|
MDA-MB-231
|
GI50 |
|
Cytotoxicity against human MDA-MB-231 cells after 72 hrs by CellTitre-Blue assay
Cytotoxicity against human MDA-MB-231 cells after 72 hrs by CellTitre-Blue assay
|
[PMID: 25528337]
|
MDA-MB-231
|
IC50 |
|
Antiproliferative activity against human MDA-MB-231 cells by SRB assay
Antiproliferative activity against human MDA-MB-231 cells by SRB assay
|
[PMID: 29655610]
|
MDA-MB-231
|
IC50 |
|
Antiproliferative activity against human MDA-MB-231 cells incubated for 24 hrs by sulforhodamine B assay
Antiproliferative activity against human MDA-MB-231 cells incubated for 24 hrs by sulforhodamine B assay
|
[PMID: 26938120]
|
MDA-MB-231
|
IC50 |
|
Cytotoxicity against human MDA-MB-231 cells after 48 hrs by alamar blue assay
Cytotoxicity against human MDA-MB-231 cells after 48 hrs by alamar blue assay
|
[PMID: 19117761]
|
MDA-MB-231
|
IC50 |
|
Antiproliferative activity against human MDA-MB-231 cells after 48 hrs by MTT assay
Antiproliferative activity against human MDA-MB-231 cells after 48 hrs by MTT assay
|
[PMID: 28792756]
|
MDA-MB-231
|
IC50 |
4.5 nM
Compound: 1a; CA-4
|
Antiproliferative activity against human MDA-MB-231 cells assessed as inhibition of cell proliferation incubated for 72 hrs by MTT assay
Antiproliferative activity against human MDA-MB-231 cells assessed as inhibition of cell proliferation incubated for 72 hrs by MTT assay
|
[PMID: 31400707]
|
MDA-MB-231
|
IC50 |
|
Cytotoxicity against human MDA-MB-231 cells assessed as [3H]thymidine incorporation after 72 hrs by microplate scintillation counter
Cytotoxicity against human MDA-MB-231 cells assessed as [3H]thymidine incorporation after 72 hrs by microplate scintillation counter
|
[PMID: 18396050]
|
MDA-MB-231
|
IC50 |
|
Antiproliferative activity against human MDA-MB-231 cells assessed as reduction in cell viability measured after 48 hrs by MTT assay
Antiproliferative activity against human MDA-MB-231 cells assessed as reduction in cell viability measured after 48 hrs by MTT assay
|
[PMID: 32339854]
|
MDA-MB-231
|
GI50 |
|
Antiproliferative activity against human MDA-MB-231 cells assessed as cell growth inhibition measured after 72 hrs by SRB assay
Antiproliferative activity against human MDA-MB-231 cells assessed as cell growth inhibition measured after 72 hrs by SRB assay
|
[PMID: 34917259]
|
MDA-MB-231
|
GI50 |
|
Antiproliferative activity against human MDA-MB-231 cells assessed as reduction in cell viability incubated for 72 hrs by SRB assay
Antiproliferative activity against human MDA-MB-231 cells assessed as reduction in cell viability incubated for 72 hrs by SRB assay
|
[PMID: 31938468]
|
MDA-MB-435
|
IC50 |
|
Cytotoxicity against human MDA-MB-435 cells after 72 hrs by MTT assay
Cytotoxicity against human MDA-MB-435 cells after 72 hrs by MTT assay
|
[PMID: 22676247]
|
MDA-MB-435
|
GI50 |
0.001 μM
Compound: 2, combretastatin A-4, CA-4, NSC 613729
|
Growth inhibition of human MDA-MB-435 cells after 48 hrs by SRB assay
Growth inhibition of human MDA-MB-435 cells after 48 hrs by SRB assay
|
[PMID: 22982122]
|
MDA-MB-435
|
GI50 |
|
Growth inhibition of human MDA-MB-435 cells after 72 hrs by MTT assay
Growth inhibition of human MDA-MB-435 cells after 72 hrs by MTT assay
|
[PMID: 27031215]
|
MDA-MB-435
|
IC50 |
0.003 μM
Compound: 1, CA-4
|
Antiproliferative activity against human MDA-MB-435 cells after 48 hrs by SRB assay
Antiproliferative activity against human MDA-MB-435 cells after 48 hrs by SRB assay
|
[PMID: 19894742]
|
MDA-MB-435
|
GI50 |
|
Cytotoxicity against human MDA-MB-435 cells assessed as growth inhibition after 48 hrs by SRB assay
Cytotoxicity against human MDA-MB-435 cells assessed as growth inhibition after 48 hrs by SRB assay
|
[PMID: 27707624]
|
MDA-MB-435
|
IC50 |
|
Antiproliferative activity against human MDA-MB-435 cell line assessed as inhibition of cell proliferation measured after 48 hrs by SRB assay
Antiproliferative activity against human MDA-MB-435 cell line assessed as inhibition of cell proliferation measured after 48 hrs by SRB assay
|
[PMID: 33310545]
|
MDA-MB-435
|
IC50 |
|
Cytotoxicity against human MDA-MB-435 cells assessed as growth inhibition after 48 hrs by SRB assay
Cytotoxicity against human MDA-MB-435 cells assessed as growth inhibition after 48 hrs by SRB assay
|
[PMID: 23332369]
|
MDA-MB-435
|
IC50 |
|
Antiproliferative activity against human MDA-MB-435 cells by SRB assay
Antiproliferative activity against human MDA-MB-435 cells by SRB assay
|
[PMID: 21786793]
|
MDA-MB-435
|
GI50 |
31.6 nM
Compound: 1, CA-4
|
Cytotoxicity against human MDA-MB-435 cells after 48 hrs by sulforhodamine B assay
Cytotoxicity against human MDA-MB-435 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 21920767]
|
MDA-MB-435
|
EC50 |
|
Cytotoxicity against human MDA-MB-435 cells assessed as growth inhibition after 48 hrs by SRB assay
Cytotoxicity against human MDA-MB-435 cells assessed as growth inhibition after 48 hrs by SRB assay
|
[PMID: 27213719]
|
MDA-MB-435
|
IC50 |
|
Antiproliferative activity against human MDA-MB-435 cells assessed as inhibition of cell growth by SRB assay
Antiproliferative activity against human MDA-MB-435 cells assessed as inhibition of cell growth by SRB assay
|
[PMID: 36889150]
|
MDA-MB-435
|
IC50 |
|
Antiproliferative activity against human MDA-MB-435 cells after 48 hrs by sulforhodamine B assay
Antiproliferative activity against human MDA-MB-435 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 30297118]
|
MDA-MB-435
|
IC50 |
|
Antiproliferative activity against human MDA-MB-435 cells after 72 hrs by sulforhodamine B assay
Antiproliferative activity against human MDA-MB-435 cells after 72 hrs by sulforhodamine B assay
|
[PMID: 30098869]
|
MDA-MB-435
|
IC50 |
|
Antiproliferative activity against human MDA-MB-435 cells assessed as reduction in cell viability by Sulforhodamine B assay
Antiproliferative activity against human MDA-MB-435 cells assessed as reduction in cell viability by Sulforhodamine B assay
|
[PMID: 33647840]
|
MDA-MB-435
|
IC50 |
|
Antiproliferative activity against human MDA-MB-435 cells after 48 hrs by sulforhodamine B assay
Antiproliferative activity against human MDA-MB-435 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 25882519]
|
MDA-MB-468
|
IC50 |
|
Antiproliferative activity against ER negative human MDA-MB-468 cells expressing CYP1A1 and CYP1B1 assessed as reduction in cell viability measured after 96 hrs by MTT assay
Antiproliferative activity against ER negative human MDA-MB-468 cells expressing CYP1A1 and CYP1B1 assessed as reduction in cell viability measured after 96 hrs by MTT assay
|
[PMID: 30935796]
|
MDA-MB-468
|
IC50 |
|
Cytotoxicity against human MDA-MB-468 cells assessed as cell viability after 4 days by MTS assay
Cytotoxicity against human MDA-MB-468 cells assessed as cell viability after 4 days by MTS assay
|
[PMID: 24210503]
|
MDA-MB-468
|
IC50 |
|
Cytotoxicity against human MDA-MB-468 cells after 72 hrs by MTT assay
Cytotoxicity against human MDA-MB-468 cells after 72 hrs by MTT assay
|
[PMID: 30472600]
|
MDA-MB-468
|
IC50 |
|
Phototoxicity against human MDA-MB-468 cells assessed as cell growth inhibition incubated for 24 hrs followed by LED illumination by MTT assay
Phototoxicity against human MDA-MB-468 cells assessed as cell growth inhibition incubated for 24 hrs followed by LED illumination by MTT assay
|
[PMID: 35964428]
|
MDA-MB-468
|
IC50 |
|
Antiproliferative activity against human MDA-MB-468 cells expressing NQO1 by MTT assay
Antiproliferative activity against human MDA-MB-468 cells expressing NQO1 by MTT assay
|
[PMID: 23010271]
|
MDA-MB-468
|
IC50 |
|
Antiproliferative activity against human MDA-MB-468 cells assessed as reduction in cell viability after 72 hrs by MTT assay
Antiproliferative activity against human MDA-MB-468 cells assessed as reduction in cell viability after 72 hrs by MTT assay
|
[PMID: 31610372]
|
MES-SA
|
IC50 |
|
Antiproliferative activity against drug sensitive Messa cell line by Alamar Blue assay
Antiproliferative activity against drug sensitive Messa cell line by Alamar Blue assay
|
[PMID: 17286393]
|
MES-SA
|
IC50 |
|
Cytotoxicity against human MESSA cells assessed as growth inhibition after 72 hrs by CellTiter-Glo assay
Cytotoxicity against human MESSA cells assessed as growth inhibition after 72 hrs by CellTiter-Glo assay
|
[PMID: 26132075]
|
MES-SA
|
IC50 |
|
Cytotoxicity against human MESSA cells assessed as growth inhibition after 72 hrs by Celltiter-Glo luminescent assay
Cytotoxicity against human MESSA cells assessed as growth inhibition after 72 hrs by Celltiter-Glo luminescent assay
|
[PMID: 23214452]
|
MES-SA
|
IC50 |
|
Cytotoxicity against human MESSA cells assessed as growth inhibition after 72 hrs by CellTitre-Glo assay
Cytotoxicity against human MESSA cells assessed as growth inhibition after 72 hrs by CellTitre-Glo assay
|
[PMID: 25025991]
|
MES-SA
|
IC50 |
|
Antiproliferative activity against human MES-SA cells after 72 hrs by resazurin assay
Antiproliferative activity against human MES-SA cells after 72 hrs by resazurin assay
|
[PMID: 26602281]
|
MES-SA/Dx5
|
IC50 |
|
Antiproliferative activity against drug resistant Messa/DX5 cell line expressing MDR1 by Alamar Blue assay
Antiproliferative activity against drug resistant Messa/DX5 cell line expressing MDR1 by Alamar Blue assay
|
[PMID: 17286393]
|
MES-SA/Dx5
|
IC50 |
|
Cytotoxicity against human MESSA/DX5 cells assessed as growth inhibition after 72 hrs by CellTiter-Glo assay
Cytotoxicity against human MESSA/DX5 cells assessed as growth inhibition after 72 hrs by CellTiter-Glo assay
|
[PMID: 26132075]
|
MES-SA/Dx5
|
IC50 |
|
Cytotoxicity against human MESSA/DX5 cells assessed as growth inhibition after 72 hrs by Celltiter-Glo luminescent assay
Cytotoxicity against human MESSA/DX5 cells assessed as growth inhibition after 72 hrs by Celltiter-Glo luminescent assay
|
[PMID: 23214452]
|
MES-SA/Dx5
|
IC50 |
|
Cytotoxicity against human MESSA/DX5 cells assessed as growth inhibition after 72 hrs by CellTitre-Glo assay
Cytotoxicity against human MESSA/DX5 cells assessed as growth inhibition after 72 hrs by CellTitre-Glo assay
|
[PMID: 25025991]
|
MES-SA/Dx5
|
IC50 |
|
Antiproliferative activity against multidrug-resistant human MES-SA/Dx5 cells assessed as reduction in cell viability incubated for 72 hrs by prestoblue dye based assay
Antiproliferative activity against multidrug-resistant human MES-SA/Dx5 cells assessed as reduction in cell viability incubated for 72 hrs by prestoblue dye based assay
|
[PMID: 33618157]
|
MES-SA/Dx5
|
IC50 |
4 nM
Compound: combretastatin A-4
|
Cell growth inhibition against,MES-SA/DX5 human uterine cancer cells using MTS assay
Cell growth inhibition against,MES-SA/DX5 human uterine cancer cells using MTS assay
|
[PMID: 12036364]
|
MES-SA/Dx5
|
IC50 |
5 nM
Compound: combretastatin A-4
|
Cell growth inhibition against MES-SA human uterine cancer cells using MTS assay
Cell growth inhibition against MES-SA human uterine cancer cells using MTS assay
|
[PMID: 12036364]
|
MGC-803
|
IC50 |
0.002 μM
Compound: 8; CA-4
|
Antiproliferative activity against human MGC-803 cells assessed as cell growth inhibition after 72 hrs by SRB assay
Antiproliferative activity against human MGC-803 cells assessed as cell growth inhibition after 72 hrs by SRB assay
|
[PMID: 34454126]
|
MGC-803
|
IC50 |
0.006 μM
Compound: 6a; CA-4
|
Antiproliferative activity against human MGC-803 cells assessed as reduction in cell viability after 24 hrs by CCK-8 assay
Antiproliferative activity against human MGC-803 cells assessed as reduction in cell viability after 24 hrs by CCK-8 assay
|
[PMID: 34458740]
|
MGC-803
|
IC50 |
|
Antiproliferative activity against human MGC-803 cells assessed as inhibition of cell growth measured after 48 hrs by MTT assay
Antiproliferative activity against human MGC-803 cells assessed as inhibition of cell growth measured after 48 hrs by MTT assay
|
[PMID: 35834904]
|
MGC-803
|
IC50 |
|
Antiproliferative activity against human MGC-803 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
Antiproliferative activity against human MGC-803 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
|
[PMID: 36252396]
|
MGC-803
|
IC50 |
|
Antiproliferative activity against human MGC803 cells after 72 hrs by CCK-8 assay
Antiproliferative activity against human MGC803 cells after 72 hrs by CCK-8 assay
|
[PMID: 30108925]
|
MGC-803
|
IC50 |
|
Antiproliferative activity against human MGC803 cells after 48 hrs by MTT assay
Antiproliferative activity against human MGC803 cells after 48 hrs by MTT assay
|
[PMID: 28792756]
|
MHCC97H
|
IC50 |
|
Antiproliferative activity against human MHCC97H cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
Antiproliferative activity against human MHCC97H cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
|
[PMID: 34649064]
|
MIA PaCa-2
|
IC50 |
|
Cytotoxicity against human MiaPaCa2 cells after 72 hrs by MTT assay
Cytotoxicity against human MiaPaCa2 cells after 72 hrs by MTT assay
|
[PMID: 17373779]
|
MIA PaCa-2
|
IC50 |
0.003 μM
Compound: 1; CA-4
|
Antiproliferative activity against human MIAPaCa2 assessed as reduction in cell viability measured after 48 hrs by SRB assay
Antiproliferative activity against human MIAPaCa2 assessed as reduction in cell viability measured after 48 hrs by SRB assay
|
[PMID: 27919655]
|
MIA PaCa-2
|
IC50 |
0.0072 μM
Compound: CA-4, 1a
|
Cytotoxicity against human MIAPaCa2 cells after 72 hrs by MTT assay
Cytotoxicity against human MIAPaCa2 cells after 72 hrs by MTT assay
|
[PMID: 20338766]
|
MIA PaCa-2
|
IC50 |
0.087 μM
Compound: 2a; CA-4
|
Cytotoxicity against human MIAPaCa2 cells assessed as cell viability after 48 hrs by SRB assay
Cytotoxicity against human MIAPaCa2 cells assessed as cell viability after 48 hrs by SRB assay
|
10.1039/C5MD00155B
|
MIA PaCa-2
|
IC50 |
|
Antiproliferative activity against human MIA PaCa-2 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
Antiproliferative activity against human MIA PaCa-2 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
|
[PMID: 33618157]
|
MIA PaCa-2
|
IC50 |
|
Cytotoxicity against human MIAPaCa2 cells after 48 hrs by alamar blue assay
Cytotoxicity against human MIAPaCa2 cells after 48 hrs by alamar blue assay
|
[PMID: 19117761]
|
MIA PaCa-2
|
IC50 |
|
Antiproliferative activity against human MIA PaCa-2 cells after 72 hrs by CellTiter Glo assay
Antiproliferative activity against human MIA PaCa-2 cells after 72 hrs by CellTiter Glo assay
|
[PMID: 35797900]
|
MIA PaCa-2
|
IC50 |
|
Antiproliferative activity against human MiaPaca2 cells assessed as cell viability after 24 hrs by Celltiter-Glo assay
Antiproliferative activity against human MiaPaca2 cells assessed as cell viability after 24 hrs by Celltiter-Glo assay
|
[PMID: 33038796]
|
MKN-45
|
IC50 |
0.0081 μM
Compound: 6a; CA-4
|
Antiproliferative activity against human MKN-45 cells assessed as reduction in cell viability after 24 hrs by CCK-8 assay
Antiproliferative activity against human MKN-45 cells assessed as reduction in cell viability after 24 hrs by CCK-8 assay
|
[PMID: 34458740]
|
MKN-45
|
IC50 |
|
Cytotoxicity against human MKN45 cells after 72 hrs by MTT assay
Cytotoxicity against human MKN45 cells after 72 hrs by MTT assay
|
[PMID: 28622907]
|
MKN-45
|
IC50 |
|
Antiproliferative activity against human MKN45 cells after 72 hrs by MTT assay
Antiproliferative activity against human MKN45 cells after 72 hrs by MTT assay
|
[PMID: 29407949]
|
MKN-45
|
IC50 |
|
Antiproliferative activity against human MKN45 cells after 72 hrs by methylene blue assay
Antiproliferative activity against human MKN45 cells after 72 hrs by methylene blue assay
|
[PMID: 26160020]
|
MKN-45
|
IC50 |
|
Cytotoxicity against human MKN45 cells after 72 hrs by methylene blue assay
Cytotoxicity against human MKN45 cells after 72 hrs by methylene blue assay
|
[PMID: 24657567]
|
MKN-45
|
IC50 |
|
Growth inhibition of human MKN45 cells after 72 hrs by methylene blue assay
Growth inhibition of human MKN45 cells after 72 hrs by methylene blue assay
|
[PMID: 22060033]
|
MKN-45
|
IC50 |
|
Antiproliferative activity against human MKN45 cells after 72 hrs by methylene blue assay
Antiproliferative activity against human MKN45 cells after 72 hrs by methylene blue assay
|
[PMID: 21641700]
|
MKN-45
|
IC50 |
|
Antiproliferative activity against human MKN45 cells after 72 hrs by methylene blue dye assay
Antiproliferative activity against human MKN45 cells after 72 hrs by methylene blue dye assay
|
[PMID: 20148562]
|
MKN-45
|
IC50 |
|
Growth inhibition of human MKN45 cells after 72 hrs by methylene blue dye assay
Growth inhibition of human MKN45 cells after 72 hrs by methylene blue dye assay
|
[PMID: 18588280]
|
MKN-45
|
IC50 |
|
Antiproliferative activity against human MKN45 cell line by methylene blue dye assay
Antiproliferative activity against human MKN45 cell line by methylene blue dye assay
|
[PMID: 17034147]
|
MOLT-3
|
IC50 |
|
Antiproliferative activity against human Molt3 cells after 72 hrs
Antiproliferative activity against human Molt3 cells after 72 hrs
|
[PMID: 17034133]
|
MOLT-4
|
GI50 |
0.003 μM
Compound: CA4, NSC 613729
|
Growth inhibition of human MOLT4 cells after 48 hrs by SRB assay
Growth inhibition of human MOLT4 cells after 48 hrs by SRB assay
|
[PMID: 24387982]
|
MOLT-4
|
GI50 |
0.003 μM
Compound: 2, combretastatin A-4, CA-4, NSC 613729
|
Growth inhibition of human MOLT4 cells after 48 hrs by SRB assay
Growth inhibition of human MOLT4 cells after 48 hrs by SRB assay
|
[PMID: 22982122]
|
MOLT-4
|
GI50 |
0.003 μM
Compound: CA4; NSC 613729
|
Cytotoxicity against human MOLT4 cells by SRB assay
Cytotoxicity against human MOLT4 cells by SRB assay
|
[PMID: 26257861]
|
MOLT-4
|
IC50 |
0.016 μM
Compound: 1, CA-4
|
Antiproliferative activity against human MOLT4 cells after 2 days by coulter counter analysis
Antiproliferative activity against human MOLT4 cells after 2 days by coulter counter analysis
|
[PMID: 22027100]
|
MOLT-4
|
IC50 |
|
Antiproliferative effect against human Molt4/C8 cells after 3 days
Antiproliferative effect against human Molt4/C8 cells after 3 days
|
[PMID: 17419607]
|
MOLT-4
|
IC50 |
|
Antiproliferative activity against human Molt4/C8 cells after 2 days by coulter counting
Antiproliferative activity against human Molt4/C8 cells after 2 days by coulter counting
|
[PMID: 20579891]
|
MOLT-4
|
IC50 |
|
Antiproliferative activity against human MOLT4 cells after 2 days by coulter counter method
Antiproliferative activity against human MOLT4 cells after 2 days by coulter counter method
|
[PMID: 19663386]
|
MOLT-4
|
IC50 |
|
Cytotoxicity against human Molt4/C8 cells assessed as growth inhibition after 48 hrs by coulter counting analysis
Cytotoxicity against human Molt4/C8 cells assessed as growth inhibition after 48 hrs by coulter counting analysis
|
[PMID: 24164557]
|
MOLT-4
|
IC50 |
|
Cytotoxicity against human Molt4/C8 cells after 2 days
Cytotoxicity against human Molt4/C8 cells after 2 days
|
[PMID: 19736015]
|
MOLT-4
|
IC50 |
|
Antiproliferative activity against human Molt4/C8 cells after 2 days
Antiproliferative activity against human Molt4/C8 cells after 2 days
|
[PMID: 18755591]
|
MOLT-4
|
GI50 |
|
Growth inhibition of human MOLT4 cells after 48 hrs by sulforhodamine B assay
Growth inhibition of human MOLT4 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 24388833]
|
MRC5
|
IC50 |
|
Growth inhibition of human MRC5 cells after 48 hrs by SRB assay
Growth inhibition of human MRC5 cells after 48 hrs by SRB assay
|
[PMID: 24900453]
|
MV4-11
|
IC50 |
0.00627 μM
Compound: 3, CA4
|
Anticancer activity against human MV4-11 cells assessed as reduction in cell proliferation after 48 hrs by WST-1 assay
Anticancer activity against human MV4-11 cells assessed as reduction in cell proliferation after 48 hrs by WST-1 assay
|
[PMID: 25466200]
|
MX1
|
IC50 |
|
Cytotoxicity against human MX1 cells assessed as growth inhibition after 72 hrs by MTT assay
Cytotoxicity against human MX1 cells assessed as growth inhibition after 72 hrs by MTT assay
|
[PMID: 23981529]
|
MX1
|
IC50 |
|
Cytotoxicity against taxol-resistant human MX1 cells assessed as growth inhibition after 72 hrs by MTT assay
Cytotoxicity against taxol-resistant human MX1 cells assessed as growth inhibition after 72 hrs by MTT assay
|
[PMID: 23981529]
|
NCI/ADR-RES
|
GI50 |
0.001 μM
Compound: 2, combretastatin A-4, CA-4, NSC 613729
|
Growth inhibition of human NCI/ADR-RES cells after 48 hrs by SRB assay
Growth inhibition of human NCI/ADR-RES cells after 48 hrs by SRB assay
|
[PMID: 22982122]
|
NCI/ADR-RES
|
EC50 |
|
Cell cycle arrest in NCI/ADR (MDR) cells by accumulation at G2/M phase
Cell cycle arrest in NCI/ADR (MDR) cells by accumulation at G2/M phase
|
[PMID: 16377187]
|
NCI/ADR-RES
|
GI50 |
|
Growth inhibition of human NCI-ADR-RES cells after 48 hrs by sulforhodamine B assay
Growth inhibition of human NCI-ADR-RES cells after 48 hrs by sulforhodamine B assay
|
[PMID: 24388833]
|
NCI/ADR-RES
|
IC50 |
|
Cytotoxicity against human NCI/ADR-RES cells assessed as growth inhibition by trypan blue exclusion assay
Cytotoxicity against human NCI/ADR-RES cells assessed as growth inhibition by trypan blue exclusion assay
|
[PMID: 23214452]
|
NCI/ADR-RES
|
IC50 |
|
Cytotoxicity against human NCI/ADR-RES cells assessed as growth inhibition after 96 hrs by Giemsa staining-based light microscopy
Cytotoxicity against human NCI/ADR-RES cells assessed as growth inhibition after 96 hrs by Giemsa staining-based light microscopy
|
[PMID: 25025991]
|
NCI/ADR-RES
|
IC50 |
|
Growth inhibition of doxorubicin-resistant human NCI-ADR-RES cells overexpressing P-glycoprotein after 96 hrs
Growth inhibition of doxorubicin-resistant human NCI-ADR-RES cells overexpressing P-glycoprotein after 96 hrs
|
[PMID: 22044164]
|
NCI/ADR-RES
|
IC50 |
|
Growth inhibition of human NCI/ADR-RES cells over expressing Pgp measured after 96 hrs by sulforhodamine B assay
Growth inhibition of human NCI/ADR-RES cells over expressing Pgp measured after 96 hrs by sulforhodamine B assay
|
[PMID: 27894589]
|
NCI/ADR-RES
|
IC50 |
|
Cytotoxicity against Pgp overexpressing human NCI-ADR-RES cells assessed as growth inhibition after 48 hrs by SRB assay
Cytotoxicity against Pgp overexpressing human NCI-ADR-RES cells assessed as growth inhibition after 48 hrs by SRB assay
|
[PMID: 26132075]
|
NCI/ADR-RES
|
IC50 |
|
Growth inhibition of human NCI/ADR-RES cells after 96 hrs by trypan blue exclusion assay
Growth inhibition of human NCI/ADR-RES cells after 96 hrs by trypan blue exclusion assay
|
[PMID: 29730191]
|
NCI/ADR-RES
|
EC50 |
|
Cytotoxicity against human NCI-ADR-RES cells assessed as inhibition of cell proliferation by SRB assay
Cytotoxicity against human NCI-ADR-RES cells assessed as inhibition of cell proliferation by SRB assay
|
[PMID: 24801610]
|
NCI-H1299
|
IC50 |
|
Antiproliferative activity against human NCI-H1299 cells measured after 48 hrs by MTT assay
Antiproliferative activity against human NCI-H1299 cells measured after 48 hrs by MTT assay
|
[PMID: 36150341]
|
NCI-H1299
|
IC50 |
|
Cytotoxicity against human H1299 cells assessed as growth inhibition after 48 hrs by MTT assay
Cytotoxicity against human H1299 cells assessed as growth inhibition after 48 hrs by MTT assay
|
[PMID: 23809851]
|
NCI-H1299
|
GI50 |
|
Cytotoxicity against human H1299 cells after 72 hrs using resazurin dye by microtiter plate fluorimeter analysis
Cytotoxicity against human H1299 cells after 72 hrs using resazurin dye by microtiter plate fluorimeter analysis
|
[PMID: 22449653]
|
NCI-H1299
|
IC50 |
|
Cytotoxicity against human H1299 cells after 72 hrs
Cytotoxicity against human H1299 cells after 72 hrs
|
[PMID: 19530698]
|
NCI-H1299
|
GI50 |
|
Cytotoxicity against human H1299 cells after 72 hrs by CellTitre-Blue assay
Cytotoxicity against human H1299 cells after 72 hrs by CellTitre-Blue assay
|
[PMID: 25528337]
|
NCI-H1437
|
IC50 |
|
Antiproliferative activity against human NCI-H1437 cells measured after 48 hrs by MTT assay
Antiproliferative activity against human NCI-H1437 cells measured after 48 hrs by MTT assay
|
[PMID: 36150341]
|
NCI-H226
|
GI50 |
0.003 μM
Compound: 2, combretastatin A-4, CA-4, NSC 613729
|
Growth inhibition of human NCI-H226 cells after 48 hrs by SRB assay
Growth inhibition of human NCI-H226 cells after 48 hrs by SRB assay
|
[PMID: 22982122]
|
NCI-H226
|
GI50 |
0.004 μM
Compound: CA4, NSC 613729
|
Growth inhibition of human NCI-H226 cells after 48 hrs by SRB assay
Growth inhibition of human NCI-H226 cells after 48 hrs by SRB assay
|
[PMID: 24387982]
|
NCI-H226
|
GI50 |
|
Growth inhibition of human NCI-H226 cells after 48 hrs by sulforhodamine B assay
Growth inhibition of human NCI-H226 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 24388833]
|
NCI-H23
|
GI50 |
0.003 μM
Compound: CA4, NSC 613729
|
Growth inhibition of human NCI-H23 cells after 48 hrs by SRB assay
Growth inhibition of human NCI-H23 cells after 48 hrs by SRB assay
|
[PMID: 24387982]
|
NCI-H23
|
GI50 |
0.003 μM
Compound: 2, combretastatin A-4, CA-4, NSC 613729
|
Growth inhibition of human NCI-H23 cells after 48 hrs by SRB assay
Growth inhibition of human NCI-H23 cells after 48 hrs by SRB assay
|
[PMID: 22982122]
|
NCI-H23
|
GI50 |
0.003 μM
Compound: CA4; NSC 613729
|
Cytotoxicity against human NCI-H23 cells by SRB assay
Cytotoxicity against human NCI-H23 cells by SRB assay
|
[PMID: 26257861]
|
NCI-H23
|
GI50 |
|
Growth inhibition of human NCI-H23 cells after 48 hrs by sulforhodamine B assay
Growth inhibition of human NCI-H23 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 24388833]
|
NCI-H322M
|
GI50 |
0.003 μM
Compound: 2, combretastatin A-4, CA-4, NSC 613729
|
Growth inhibition of human NCI-H322M cells after 48 hrs by SRB assay
Growth inhibition of human NCI-H322M cells after 48 hrs by SRB assay
|
[PMID: 22982122]
|
NCI-H322M
|
GI50 |
0.007 μM
Compound: CA4, NSC 613729
|
Growth inhibition of human NCI-H322M cells after 48 hrs by SRB assay
Growth inhibition of human NCI-H322M cells after 48 hrs by SRB assay
|
[PMID: 24387982]
|
NCI-H322M
|
GI50 |
|
Growth inhibition of human NCI-H322M cells after 48 hrs by sulforhodamine B assay
Growth inhibition of human NCI-H322M cells after 48 hrs by sulforhodamine B assay
|
[PMID: 24388833]
|
NCI-H460
|
GI50 |
< 0.01 μM
Compound: 1, CA-4
|
Growth inhibition of human NCI-H460 cells after 3 days by crystal violet staining
Growth inhibition of human NCI-H460 cells after 3 days by crystal violet staining
|
[PMID: 19954252]
|
NCI-H460
|
GI50 |
0.0006 μg/mL
Compound: CA4
|
Cytotoxicity against human NCI-H460 cells after 48 hrs by SRB assay
Cytotoxicity against human NCI-H460 cells after 48 hrs by SRB assay
|
[PMID: 18710804]
|
NCI-H460
|
GI50 |
0.0006 μg/mL
Compound: 1a, CA4
|
Growth inhibition of human NCI-H460 cells after 48 hrs by sulforhodamine B assay
Growth inhibition of human NCI-H460 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 22324723]
|
NCI-H460
|
GI50 |
0.0006 μg/mL
Compound: 2a
|
Growth inhibition of human NCI-H460 cells after 48 hrs by sulforhodamine B assay
Growth inhibition of human NCI-H460 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 19719153]
|
NCI-H460
|
GI50 |
0.0006 μg/mL
Compound: 1a, CA4
|
Cytotoxicity against human NCI-H460 cells after 48 hrs by sulforhodamine B assay
Cytotoxicity against human NCI-H460 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 16252907]
|
NCI-H460
|
GI50 |
0.0006 μg/mL
Compound: 3, CA4
|
Antitumor activity against human NCI-H460 cells by sulforhodamine B assay
Antitumor activity against human NCI-H460 cells by sulforhodamine B assay
|
[PMID: 19228038]
|
NCI-H460
|
GI50 |
0.0006 μM
Compound: CA4, combretastatin A4
|
Cytotoxicity against human NCIH460 cells after 48 hrs by SRB assay
Cytotoxicity against human NCIH460 cells after 48 hrs by SRB assay
|
[PMID: 18303849]
|
NCI-H460
|
GI50 |
|
Growth inhibition of human NCI-H460 after 48 hrs by SRB assay
Growth inhibition of human NCI-H460 after 48 hrs by SRB assay
|
[PMID: 18722127]
|
NCI-H460
|
GI50 |
|
Cytotoxicity against human NCI-H460 cells assessed as growth inhibition measured after 48 hrs by SRB assay
Cytotoxicity against human NCI-H460 cells assessed as growth inhibition measured after 48 hrs by SRB assay
|
[PMID: 31059248]
|
NCI-H460
|
GI50 |
0.00223 μM
Compound: CA4, CA4P
|
Cytotoxicity against human NCI-H460 cells after 48 hrs by SRB assay
Cytotoxicity against human NCI-H460 cells after 48 hrs by SRB assay
|
[PMID: 24183586]
|
NCI-H460
|
GI50 |
0.0028 μM
Compound: 2, CA4
|
Cytotoxicity against human NCI-H460 cells by SRB assay
Cytotoxicity against human NCI-H460 cells by SRB assay
|
[PMID: 24016002]
|
NCI-H460
|
GI50 |
|
Growth inhibition of human NCI-H460 cells by sulforhodamine B assay
Growth inhibition of human NCI-H460 cells by sulforhodamine B assay
|
[PMID: 23772309]
|
NCI-H460
|
GI50 |
0.003 μM
Compound: CA4, NSC 613729
|
Growth inhibition of human NCI-H460 cells after 48 hrs by SRB assay
Growth inhibition of human NCI-H460 cells after 48 hrs by SRB assay
|
[PMID: 24387982]
|
NCI-H460
|
GI50 |
|
Cytotoxicity against human NCI-H460 cells after 48 hrs by SRB assay
Cytotoxicity against human NCI-H460 cells after 48 hrs by SRB assay
|
[PMID: 23993969]
|
NCI-H460
|
GI50 |
|
Cytotoxicity against human NCI-H460 cells assessed as reduction in cell viability incubated for 48 hrs by SRB assay
Cytotoxicity against human NCI-H460 cells assessed as reduction in cell viability incubated for 48 hrs by SRB assay
|
[PMID: 31534659]
|
NCI-H460
|
GI50 |
0.007 μM
Compound: 2, combretastatin A-4, CA-4, NSC 613729
|
Growth inhibition of human NCI-H460 cells after 48 hrs by SRB assay
Growth inhibition of human NCI-H460 cells after 48 hrs by SRB assay
|
[PMID: 22982122]
|
NCI-H460
|
IC50 |
|
Cytotoxicity against human NCI-H460 cells after 68 hrs by MTT assay
Cytotoxicity against human NCI-H460 cells after 68 hrs by MTT assay
|
[PMID: 32243160]
|
NCI-H460
|
IC50 |
0.048 μM
Compound: CA-4; B
|
Antiproliferative activity against human NCI-H460 cells after 48 hrs by MTT assay
Antiproliferative activity against human NCI-H460 cells after 48 hrs by MTT assay
|
[PMID: 28774575]
|
NCI-H460
|
IC50 |
|
Antiproliferative activity against human NCI-H460 cells after 48 hrs by MTT assay
Antiproliferative activity against human NCI-H460 cells after 48 hrs by MTT assay
|
[PMID: 34311158]
|
NCI-H460
|
IC50 |
|
Antiproliferative activity against human H460 cells after 72 hrs by MTT assay
Antiproliferative activity against human H460 cells after 72 hrs by MTT assay
|
[PMID: 29407949]
|
NCI-H460
|
IC50 |
|
Cytotoxicity against human NCI-H460 cells after 72 hrs by MTT assay
Cytotoxicity against human NCI-H460 cells after 72 hrs by MTT assay
|
[PMID: 28622907]
|
NCI-H460
|
IC50 |
|
Cytotoxicity against human H460 cells by sulforhodamine B test
Cytotoxicity against human H460 cells by sulforhodamine B test
|
[PMID: 18783207]
|
NCI-H460
|
IC50 |
1.24 nM
Compound: 1, combretastatin A-4, CA-4
|
Cytotoxic activity against human NCI-H460 cells after 72 hrs by sulforhodamine B test
Cytotoxic activity against human NCI-H460 cells after 72 hrs by sulforhodamine B test
|
[PMID: 18396857]
|
NCI-H460
|
IC50 |
|
Antiproliferative activity against human H460 cell line by methylene blue dye assay
Antiproliferative activity against human H460 cell line by methylene blue dye assay
|
[PMID: 17034147]
|
NCI-H460
|
IC50 |
|
Antiproliferative activity against human H460 cells after 72 hrs by methylene blue assay
Antiproliferative activity against human H460 cells after 72 hrs by methylene blue assay
|
[PMID: 21641700]
|
NCI-H460
|
IC50 |
|
Antiproliferative activity against human H460 cells after 72 hrs by methylene blue dye assay
Antiproliferative activity against human H460 cells after 72 hrs by methylene blue dye assay
|
[PMID: 20148562]
|
NCI-H460
|
IC50 |
|
Growth inhibition of human H460 cells after 72 hrs by methylene blue dye assay
Growth inhibition of human H460 cells after 72 hrs by methylene blue dye assay
|
[PMID: 18588280]
|
NCI-H460
|
GI50 |
|
Growth inhibition of human NCI-H460 cells after 48 hrs by sulforhodamine B assay
Growth inhibition of human NCI-H460 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 24388833]
|
NCI-H460
|
IC50 |
35.81 μM
Compound: 3; CA-4
|
Growth inhibition of human NCI-H460 cells incubated for 48 hrs by MTT assay
Growth inhibition of human NCI-H460 cells incubated for 48 hrs by MTT assay
|
[PMID: 27172319]
|
NCI-H460
|
IC50 |
|
Cytotoxicity against human NCI-H460 cells by alamar blue assay
Cytotoxicity against human NCI-H460 cells by alamar blue assay
|
[PMID: 22137934]
|
NCI-H460
|
GI50 |
|
Cytotoxicity against human NCI-H460 cells assessed as growth inhibition after 48 hrs by SRB assay
Cytotoxicity against human NCI-H460 cells assessed as growth inhibition after 48 hrs by SRB assay
|
[PMID: 26852340]
|
NCI-H460
|
GI50 |
6 x 10 -4 μg/mL
Compound: Z-1b
|
Cytotoxicity against human NCI-H460 cells after 48 hrs by sulforhodamine B assay
Cytotoxicity against human NCI-H460 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 19709889]
|
NCI-H522
|
GI50 |
0.001 μM
Compound: 2, combretastatin A-4, CA-4, NSC 613729
|
Growth inhibition of human NCI-H522 cells after 48 hrs by SRB assay
Growth inhibition of human NCI-H522 cells after 48 hrs by SRB assay
|
[PMID: 22982122]
|
NCI-H522
|
GI50 |
0.002 μM
Compound: CA4, NSC 613729
|
Growth inhibition of human NCI-H522 cells after 48 hrs by SRB assay
Growth inhibition of human NCI-H522 cells after 48 hrs by SRB assay
|
[PMID: 24387982]
|
NCI-H522
|
GI50 |
0.002 μM
Compound: CA4; NSC 613729
|
Cytotoxicity against human NCI-H522 cells by SRB assay
Cytotoxicity against human NCI-H522 cells by SRB assay
|
[PMID: 26257861]
|
NCI-H522
|
GI50 |
|
Growth inhibition of human NCI-H522 cells after 48 hrs by sulforhodamine B assay
Growth inhibition of human NCI-H522 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 27031215]
|
NCI-H522
|
GI50 |
|
Growth inhibition of human NCI-H522 cells after 48 hrs by sulforhodamine B assay
Growth inhibition of human NCI-H522 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 24388833]
|
NCI-H69
|
IC50 |
|
Antiproliferative activity against drug sensitive NCI-H69 cell line by Alamar Blue assay
Antiproliferative activity against drug sensitive NCI-H69 cell line by Alamar Blue assay
|
[PMID: 17286393]
|
NCI-N87
|
IC50 |
|
Antiproliferative activity against human NCI-N87 cells after 72 hrs by CellTiter Glo assay
Antiproliferative activity against human NCI-N87 cells after 72 hrs by CellTiter Glo assay
|
[PMID: 35797900]
|
NCI-N87
|
IC50 |
|
Cytotoxicity against human NCI-N87 cells assessed as cell viability after 4 days by MTS assay
Cytotoxicity against human NCI-N87 cells assessed as cell viability after 4 days by MTS assay
|
[PMID: 24210503]
|
NCM460
|
IC50 |
|
Cytotoxicity against human NCM460 cells assessed as reduction in cell proliferation after 48 hrs by WST-1 assay
Cytotoxicity against human NCM460 cells assessed as reduction in cell proliferation after 48 hrs by WST-1 assay
|
[PMID: 25466200]
|
NCM460
|
IC50 |
|
Cytotoxicity against human NCM460 cells assessed as reduction in cell viability measured after 48 hrs by CCK8 assay
Cytotoxicity against human NCM460 cells assessed as reduction in cell viability measured after 48 hrs by CCK8 assay
|
[PMID: 33280898]
|
NCM460
|
CC50 |
|
Cytotoxicity against human NCM460 cells measured after 48 hrs by MTT assay
Cytotoxicity against human NCM460 cells measured after 48 hrs by MTT assay
|
[PMID: 36150341]
|
NIH3T3
|
IC50 |
0.02 μM
Compound: 1, CA-4
|
Cytotoxicity against mouse NIH/3T3 cells assessed as growth inhibition after 48 hrs by MTT assay
Cytotoxicity against mouse NIH/3T3 cells assessed as growth inhibition after 48 hrs by MTT assay
|
[PMID: 23566762]
|
NIH3T3
|
IC50 |
|
Cytotoxicity against mouse NIH/3T3 cells after 48 hrs by MTT assay
Cytotoxicity against mouse NIH/3T3 cells after 48 hrs by MTT assay
|
[PMID: 24238904]
|
OVCAR
|
IC50 |
|
Cytotoxicity against human OVCAR cells assessed as [3H]thymidine incorporation after 72 hrs by microplate scintillation counter
Cytotoxicity against human OVCAR cells assessed as [3H]thymidine incorporation after 72 hrs by microplate scintillation counter
|
[PMID: 18396050]
|
OVCAR-3
|
GI50 |
0.001 μM
Compound: 2, combretastatin A-4, CA-4, NSC 613729
|
Growth inhibition of human OVCAR3 cells after 48 hrs by SRB assay
Growth inhibition of human OVCAR3 cells after 48 hrs by SRB assay
|
[PMID: 22982122]
|
OVCAR-3
|
GI50 |
0.002 μM
Compound: CA4, NSC 613729
|
Growth inhibition of human OVCAR3 cells after 48 hrs by SRB assay
Growth inhibition of human OVCAR3 cells after 48 hrs by SRB assay
|
[PMID: 24387982]
|
OVCAR-3
|
GI50 |
0.002 μM
Compound: CA4; NSC 613729
|
Cytotoxicity against human OVCAR3 cells by SRB assay
Cytotoxicity against human OVCAR3 cells by SRB assay
|
[PMID: 26257861]
|
OVCAR-3
|
GI50 |
|
Growth inhibition of human OVCAR3 cells after 48 hrs by sulforhodamine B assay
Growth inhibition of human OVCAR3 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 27031215]
|
OVCAR-3
|
GI50 |
|
Growth inhibition of human OVCAR3 cells after 48 hrs by sulforhodamine B assay
Growth inhibition of human OVCAR3 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 24388833]
|
OVCAR-3
|
EC50 |
|
Cytotoxicity against human OVCAR3 cells assessed as reduction in cell viability after 72 hrs by WST8 assay
Cytotoxicity against human OVCAR3 cells assessed as reduction in cell viability after 72 hrs by WST8 assay
|
[PMID: 28197314]
|
OVCAR-3
|
GI50 |
39.8 nM
Compound: 1, CA-4
|
Cytotoxicity against human OVCAR3 cells after 48 hrs by sulforhodamine B assay
Cytotoxicity against human OVCAR3 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 21920767]
|
OVCAR-4
|
GI50 |
0.014 μM
Compound: CA4, NSC 613729
|
Growth inhibition of human OVCAR4 cells after 48 hrs by SRB assay
Growth inhibition of human OVCAR4 cells after 48 hrs by SRB assay
|
[PMID: 24387982]
|
OVCAR-4
|
GI50 |
0.014 μM
Compound: CA4; NSC 613729
|
Cytotoxicity against human OVCAR4 cells by SRB assay
Cytotoxicity against human OVCAR4 cells by SRB assay
|
[PMID: 26257861]
|
OVCAR-4
|
GI50 |
0.015 μM
Compound: 2, combretastatin A-4, CA-4, NSC 613729
|
Growth inhibition of human OVCAR4 cells after 48 hrs by SRB assay
Growth inhibition of human OVCAR4 cells after 48 hrs by SRB assay
|
[PMID: 22982122]
|
OVCAR-4
|
GI50 |
|
Growth inhibition of human OVCAR4 cells after 48 hrs by sulforhodamine B assay
Growth inhibition of human OVCAR4 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 24388833]
|
OVCAR-5
|
GI50 |
0.1 μM
Compound: CA4, NSC 613729
|
Growth inhibition of human OVCAR5 cells after 48 hrs by SRB assay
Growth inhibition of human OVCAR5 cells after 48 hrs by SRB assay
|
[PMID: 24387982]
|
OVCAR-5
|
GI50 |
0.1 μM
Compound: 2, combretastatin A-4, CA-4, NSC 613729
|
Growth inhibition of human OVCAR5 cells after 48 hrs by SRB assay
Growth inhibition of human OVCAR5 cells after 48 hrs by SRB assay
|
[PMID: 22982122]
|
OVCAR-5
|
GI50 |
|
Growth inhibition of human OVCAR5 cells after 48 hrs by sulforhodamine B assay
Growth inhibition of human OVCAR5 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 24388833]
|
OVCAR-8
|
GI50 |
0.003 μM
Compound: CA4, NSC 613729
|
Growth inhibition of human OVCAR8 cells after 48 hrs by SRB assay
Growth inhibition of human OVCAR8 cells after 48 hrs by SRB assay
|
[PMID: 24387982]
|
OVCAR-8
|
GI50 |
0.003 μM
Compound: 2, combretastatin A-4, CA-4, NSC 613729
|
Growth inhibition of human OVCAR8 cells after 48 hrs by SRB assay
Growth inhibition of human OVCAR8 cells after 48 hrs by SRB assay
|
[PMID: 22982122]
|
OVCAR-8
|
IC50 |
|
Cytotoxicity against human OVCAR8 cells assessed as growth inhibition by trypan blue exclusion assay
Cytotoxicity against human OVCAR8 cells assessed as growth inhibition by trypan blue exclusion assay
|
[PMID: 23214452]
|
OVCAR-8
|
IC50 |
|
Cytotoxicity against human OVCAR8 cells assessed as growth inhibition after 96 hrs by Giemsa staining-based light microscopy
Cytotoxicity against human OVCAR8 cells assessed as growth inhibition after 96 hrs by Giemsa staining-based light microscopy
|
[PMID: 25025991]
|
OVCAR-8
|
IC50 |
|
Growth inhibition of human OVCAR8 cells overexpressing P-glycoprotein after 96 hrs
Growth inhibition of human OVCAR8 cells overexpressing P-glycoprotein after 96 hrs
|
[PMID: 22044164]
|
OVCAR-8
|
IC50 |
|
Growth inhibition of human OVCAR8 cells measured after 96 hrs by sulforhodamine B assay
Growth inhibition of human OVCAR8 cells measured after 96 hrs by sulforhodamine B assay
|
[PMID: 27894589]
|
OVCAR-8
|
IC50 |
|
Cytotoxicity against human OVCAR8 cells assessed as growth inhibition after 48 hrs by SRB assay
Cytotoxicity against human OVCAR8 cells assessed as growth inhibition after 48 hrs by SRB assay
|
[PMID: 26132075]
|
OVCAR-8
|
GI50 |
|
Growth inhibition of human OVCAR8 cells after 48 hrs by sulforhodamine B assay
Growth inhibition of human OVCAR8 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 24388833]
|
OVCAR-8
|
IC50 |
|
Growth inhibition of human OVCAR8 cells after 96 hrs by trypan blue exclusion assay
Growth inhibition of human OVCAR8 cells after 96 hrs by trypan blue exclusion assay
|
[PMID: 29730191]
|
OVCAR-8
|
EC50 |
|
Cytotoxicity against human OVCAR8 cells assessed as inhibition of cell proliferation by SRB assay
Cytotoxicity against human OVCAR8 cells assessed as inhibition of cell proliferation by SRB assay
|
[PMID: 24801610]
|
P388
|
ED50 |
0.0003 μg/mL
Compound: 1a, CA4
|
Cytotoxicity against mouse P388 cells after 48 hrs by sulforhodamine B assay
Cytotoxicity against mouse P388 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 16252907]
|
P388
|
ED50 |
0.0003 μg/mL
Compound: 1a, CA4
|
Growth inhibition of mouse P388 cells after 48 hrs by Z1 Beckman/Coulter particle counter analysis
Growth inhibition of mouse P388 cells after 48 hrs by Z1 Beckman/Coulter particle counter analysis
|
[PMID: 22324723]
|
P388
|
IC50 |
0.0026 μM
Compound: Combrestatin A4
|
Cytotoxicity against mouse P388 cells assessed as growth inhibition after 5 days by MTT assay
Cytotoxicity against mouse P388 cells assessed as growth inhibition after 5 days by MTT assay
|
10.1039/C2MD20199B
|
P388
|
ED50 |
3 x 10 -2 μg/mL
Compound: Z-1b
|
Cytotoxicity against mouse P388 cells after 48 hrs by sulforhodamine B assay
Cytotoxicity against mouse P388 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 19709889]
|
P388
|
IC50 |
|
Antiproliferative activity against mouse P388 cells after 5 days by MTT assay
Antiproliferative activity against mouse P388 cells after 5 days by MTT assay
|
[PMID: 19837594]
|
PA-1
|
IC50 |
|
Cytotoxicity against human PA1 cells after 72 hrs by MTT assay
Cytotoxicity against human PA1 cells after 72 hrs by MTT assay
|
[PMID: 17373779]
|
PANC-1
|
IC50 |
|
Cytotoxicity against human PANC1 cells after 72 hrs by XTT assay
Cytotoxicity against human PANC1 cells after 72 hrs by XTT assay
|
[PMID: 30017114]
|
PBL
|
IC50 |
|
Cytotoxicity against human PBL cells assessed as reduction in cell viability after 72 hrs by MTS assay
Cytotoxicity against human PBL cells assessed as reduction in cell viability after 72 hrs by MTS assay
|
[PMID: 29202409]
|
PBL
|
IC50 |
|
Cytotoxicity against human PBL cells assessed as reduction in cell proliferation after 72 hrs by MTT assay
Cytotoxicity against human PBL cells assessed as reduction in cell proliferation after 72 hrs by MTT assay
|
[PMID: 29202409]
|
PBMC
|
IC50 |
|
Inhibition of LPS-induced TNFalpha production in human PBMC preincubated 1 hr prior to LPS stimulation measured after 18 to 20 hrs by ELISA
Inhibition of LPS-induced TNFalpha production in human PBMC preincubated 1 hr prior to LPS stimulation measured after 18 to 20 hrs by ELISA
|
[PMID: 21955454]
|
PC-3
|
GI50 |
0.001 μM
Compound: 2, combretastatin A-4, CA-4, NSC 613729
|
Growth inhibition of human PC3 cells after 48 hrs by SRB assay
Growth inhibition of human PC3 cells after 48 hrs by SRB assay
|
[PMID: 22982122]
|
PC-3
|
GI50 |
|
Growth inhibition of human PC3 cells after 48 hrs by sulforhodamine B assay
Growth inhibition of human PC3 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 27031215]
|
PC-3
|
IC50 |
0.0034 μM
Compound: 3; CA-4
|
Growth inhibition of human PC3 cells incubated for 72 hrs by MTT assay
Growth inhibition of human PC3 cells incubated for 72 hrs by MTT assay
|
[PMID: 27172319]
|
PC-3
|
IC50 |
|
Cytotoxicity against human PC3 cells assessed as reduction in cell viability incubated for 48 hrs by SRB assay
Cytotoxicity against human PC3 cells assessed as reduction in cell viability incubated for 48 hrs by SRB assay
|
[PMID: 28803799]
|
PC-3
|
GI50 |
|
Antiproliferative activity against human PC3 cells after 48 hrs by MTT assay
Antiproliferative activity against human PC3 cells after 48 hrs by MTT assay
|
10.1039/C5MD00139K
|
PC-3
|
IC50 |
|
Antiproliferative activity against human PC3 cells measured after 48 hrs by MTT assay
Antiproliferative activity against human PC3 cells measured after 48 hrs by MTT assay
|
[PMID: 27721152]
|
PC-3
|
IC50 |
|
Antiproliferative activity against human PC3 cells assessed as growth inhibition after 48 hrs by MTT assay
Antiproliferative activity against human PC3 cells assessed as growth inhibition after 48 hrs by MTT assay
|
[PMID: 22044164]
|
PC-3
|
IC50 |
|
Anticancer activity against human PC3 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay
Anticancer activity against human PC3 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay
|
[PMID: 31954880]
|
PC-3
|
IC50 |
|
Cytotoxicity against human PC3 cells after 48 hrs by sulforhodamine B assay
Cytotoxicity against human PC3 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 23810282]
|
PC-3
|
IC50 |
|
Antiproliferative activity against human PC3 cells after 72 hrs
Antiproliferative activity against human PC3 cells after 72 hrs
|
[PMID: 17034133]
|
PC-3
|
IC50 |
|
Growth inhibition of human PC3 cells after 48 hrs by SRB assay
Growth inhibition of human PC3 cells after 48 hrs by SRB assay
|
[PMID: 24900453]
|
PC-3
|
IC50 |
|
Cytotoxicity against human PC3 cells assessed as growth inhibition after 48 hrs by MTT assay
Cytotoxicity against human PC3 cells assessed as growth inhibition after 48 hrs by MTT assay
|
[PMID: 27810596]
|
PC-3
|
IC50 |
3.53 μM
Compound: CA-4; B
|
Antiproliferative activity against human PC3 cells after 48 hrs by MTT assay
Antiproliferative activity against human PC3 cells after 48 hrs by MTT assay
|
[PMID: 28774575]
|
PC-3
|
IC50 |
|
Cytotoxicity against human PC3 cells after 48 hrs by MTT assay
Cytotoxicity against human PC3 cells after 48 hrs by MTT assay
|
[PMID: 19665898]
|
RKO
|
IC50 |
|
Antiproliferative activity against human RKO cells measured after 48 hrs by MTT assay
Antiproliferative activity against human RKO cells measured after 48 hrs by MTT assay
|
[PMID: 36150341]
|
RKO
|
IC50 |
|
Antiproliferative activity against human RKO cells after 48 hrs by MTT assay
Antiproliferative activity against human RKO cells after 48 hrs by MTT assay
|
[PMID: 28792756]
|
RL
|
IC50 |
|
Antiproliferative activity against human RL cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
Antiproliferative activity against human RL cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
|
[PMID: 33618157]
|
RPMI-8226
|
GI50 |
0.003 μM
Compound: CA4, NSC 613729
|
Growth inhibition of human RPMI8226 cells after 48 hrs by SRB assay
Growth inhibition of human RPMI8226 cells after 48 hrs by SRB assay
|
[PMID: 24387982]
|
RPMI-8226
|
GI50 |
0.003 μM
Compound: 2, combretastatin A-4, CA-4, NSC 613729
|
Growth inhibition of human RPMI8226 cells after 48 hrs by SRB assay
Growth inhibition of human RPMI8226 cells after 48 hrs by SRB assay
|
[PMID: 22982122]
|
RPMI-8226
|
GI50 |
0.003 μM
Compound: CA4; NSC 613729
|
Cytotoxicity against human RPMI8226 cells by SRB assay
Cytotoxicity against human RPMI8226 cells by SRB assay
|
[PMID: 26257861]
|
RPMI-8226
|
GI50 |
|
Growth inhibition of human RPMI8226 cells after 48 hrs by sulforhodamine B assay
Growth inhibition of human RPMI8226 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 24388833]
|
RS4-11
|
IC50 |
|
Antiproliferative activity against human RS4:11 cells after 72 hrs by MTT assay
Antiproliferative activity against human RS4:11 cells after 72 hrs by MTT assay
|
[PMID: 30633509]
|
RS4-11
|
IC50 |
0.8 nM
Compound: 1a, CA-4
|
Antiproliferative activity against human RS4:11 cells after 72 hrs by (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide test
Antiproliferative activity against human RS4:11 cells after 72 hrs by (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide test
|
[PMID: 25785605]
|
RT-112
|
IC50 |
0.0216 μM
Compound: CA-4, 1a
|
Cytotoxicity against human RT112 cells after 72 hrs by MTT assay
Cytotoxicity against human RT112 cells after 72 hrs by MTT assay
|
[PMID: 20338766]
|
RXF 393
|
GI50 |
0.002 μM
Compound: CA4, NSC 613729
|
Growth inhibition of human RXF393 cells after 48 hrs by SRB assay
Growth inhibition of human RXF393 cells after 48 hrs by SRB assay
|
[PMID: 24387982]
|
RXF 393
|
GI50 |
0.002 μM
Compound: 2, combretastatin A-4, CA-4, NSC 613729
|
Growth inhibition of human RXF393 cells after 48 hrs by SRB assay
Growth inhibition of human RXF393 cells after 48 hrs by SRB assay
|
[PMID: 22982122]
|
RXF 393
|
GI50 |
|
Growth inhibition of human RXF393 cells after 48 hrs by sulforhodamine B assay
Growth inhibition of human RXF393 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 24388833]
|
SAOS-2
|
IC50 |
0.0114 μM
Compound: 3, CA4
|
Anticancer activity against human Saos2 cells assessed as reduction in cell proliferation after 48 hrs by WST-1 assay
Anticancer activity against human Saos2 cells assessed as reduction in cell proliferation after 48 hrs by WST-1 assay
|
[PMID: 25466200]
|
SEM
|
IC50 |
0.005 μM
Compound: CA-4;1a
|
Antiproliferative activity against human SEM cells assessed as reduction in cell viability after 72 hrs by MTT assay
Antiproliferative activity against human SEM cells assessed as reduction in cell viability after 72 hrs by MTT assay
|
[PMID: 33550186]
|
SEM
|
IC50 |
|
Growth inhibition of human SEM cells after 72 hrs by MTT assay
Growth inhibition of human SEM cells after 72 hrs by MTT assay
|
[PMID: 25025853]
|
SEM
|
IC50 |
|
Cytotoxicity against human SEM cells after 72 hrs by MTT assay
Cytotoxicity against human SEM cells after 72 hrs by MTT assay
|
[PMID: 23445496]
|
SEM
|
IC50 |
5.1 nM
Compound: 1a; CA-4
|
Antiproliferative activity against human SEM cells assessed as inhibition of cell proliferation incubated for 72 hrs by MTT assay
Antiproliferative activity against human SEM cells assessed as inhibition of cell proliferation incubated for 72 hrs by MTT assay
|
[PMID: 31400707]
|
SF-188
|
IC50 |
|
Cytotoxicity against human SF188 cells assessed as cell viability after 72 hrs by resazurin reduction assay
Cytotoxicity against human SF188 cells assessed as cell viability after 72 hrs by resazurin reduction assay
|
[PMID: 26599530]
|
SF-268
|
GI50 |
< 0.001 μg/mL
Compound: 1a, CA4
|
Growth inhibition of human SF268 cells after 48 hrs by sulforhodamine B assay
Growth inhibition of human SF268 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 22324723]
|
SF-268
|
GI50 |
< 0.001 μg/mL
Compound: 1a, CA4
|
Cytotoxicity against human SF268 cells after 48 hrs by sulforhodamine B assay
Cytotoxicity against human SF268 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 16252907]
|
SF-268
|
GI50 |
> 0.01 μg/mL
Compound: 2a
|
Growth inhibition of human SF268 cells after 48 hrs by sulforhodamine B assay
Growth inhibition of human SF268 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 19719153]
|
SF-268
|
GI50 |
> 1 x 10 -2 μg/mL
Compound: Z-1b
|
Cytotoxicity against human SF268 cells after 48 hrs by sulforhodamine B assay
Cytotoxicity against human SF268 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 19709889]
|
SF-268
|
GI50 |
0.006 μM
Compound: CA4, NSC 613729
|
Growth inhibition of human SF268 cells after 48 hrs by SRB assay
Growth inhibition of human SF268 cells after 48 hrs by SRB assay
|
[PMID: 24387982]
|
SF-268
|
GI50 |
0.006 μM
Compound: 2, combretastatin A-4, CA-4, NSC 613729
|
Growth inhibition of human SF268 cells after 48 hrs by SRB assay
Growth inhibition of human SF268 cells after 48 hrs by SRB assay
|
[PMID: 22982122]
|
SF-268
|
GI50 |
0.006 μM
Compound: CA4; NSC 613729
|
Cytotoxicity against human SF268 cells by SRB assay
Cytotoxicity against human SF268 cells by SRB assay
|
[PMID: 26257861]
|
SF-268
|
GI50 |
|
Growth inhibition of human SF268 cells after 48 hrs by sulforhodamine B assay
Growth inhibition of human SF268 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 24388833]
|
SF-295
|
GI50 |
0.003 μM
Compound: 2, combretastatin A-4, CA-4, NSC 613729
|
Growth inhibition of human SF295 cells after 48 hrs by SRB assay
Growth inhibition of human SF295 cells after 48 hrs by SRB assay
|
[PMID: 22982122]
|
SF-295
|
GI50 |
0.004 μM
Compound: CA4, NSC 613729
|
Growth inhibition of human SF295 cells after 48 hrs by SRB assay
Growth inhibition of human SF295 cells after 48 hrs by SRB assay
|
[PMID: 24387982]
|
SF-295
|
GI50 |
0.004 μM
Compound: CA4; NSC 613729
|
Cytotoxicity against human SF295 cells by SRB assay
Cytotoxicity against human SF295 cells by SRB assay
|
[PMID: 26257861]
|
SF-295
|
GI50 |
|
Growth inhibition of human SF295 cells after 48 hrs by sulforhodamine B assay
Growth inhibition of human SF295 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 27031215]
|
SF-295
|
GI50 |
|
Growth inhibition of human SF295 cells after 48 hrs by sulforhodamine B assay
Growth inhibition of human SF295 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 24388833]
|
SF-295
|
GI50 |
63.1 nM
Compound: 1, CA-4
|
Cytotoxicity against human SF295 cells after 48 hrs by sulforhodamine B assay
Cytotoxicity against human SF295 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 21920767]
|
SF-539
|
GI50 |
0.002 μM
Compound: 2, combretastatin A-4, CA-4, NSC 613729
|
Growth inhibition of human SF539 cells after 48 hrs by SRB assay
Growth inhibition of human SF539 cells after 48 hrs by SRB assay
|
[PMID: 22982122]
|
SF-539
|
GI50 |
0.003 μM
Compound: CA4, NSC 613729
|
Growth inhibition of human SF539 cells after 48 hrs by SRB assay
Growth inhibition of human SF539 cells after 48 hrs by SRB assay
|
[PMID: 24387982]
|
SF-539
|
GI50 |
0.003 μM
Compound: CA4; NSC 613729
|
Cytotoxicity against human SF539 cells by SRB assay
Cytotoxicity against human SF539 cells by SRB assay
|
[PMID: 26257861]
|
SF-539
|
GI50 |
|
Growth inhibition of human SF539 cells after 48 hrs by sulforhodamine B assay
Growth inhibition of human SF539 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 24388833]
|
SGC-7901
|
IC50 |
0.012 μM
Compound: 1; CA-4
|
Cytotoxicity against human SGC7901 cells assessed as reduction in cell viability after 24 hrs by MTT assay
Cytotoxicity against human SGC7901 cells assessed as reduction in cell viability after 24 hrs by MTT assay
|
[PMID: 27994764]
|
SGC-7901
|
IC50 |
0.012 μM
Compound: 2; CA-4
|
Antiproliferative activity against human SGC7901 cells after 72 hrs by MTT assay
Antiproliferative activity against human SGC7901 cells after 72 hrs by MTT assay
|
[PMID: 30245397]
|
SGC-7901
|
IC50 |
0.024 μM
Compound: 2; CA-4
|
Antiproliferative activity against human SGC7901 cells assessed as reduction in cell viability after 72 hrs by MTT assay
Antiproliferative activity against human SGC7901 cells assessed as reduction in cell viability after 72 hrs by MTT assay
|
10.1039/C5MD00150A
|
SGC-7901
|
IC50 |
0.024 μM
Compound: 1a; CA-4
|
Anti-proliferative activity against human SGC7901 cells after 72 hrs by MTT assay
Anti-proliferative activity against human SGC7901 cells after 72 hrs by MTT assay
|
10.1039/C5MD00028A
|
SGC-7901
|
IC50 |
|
Antiproliferative activity against human SGC-7901 cells measured after 72 hrs by MTT assay
Antiproliferative activity against human SGC-7901 cells measured after 72 hrs by MTT assay
|
[PMID: 31787361]
|
SGC-7901
|
IC50 |
|
Antiproliferative activity against human SGC7901 cells measured after 72 hrs by MTT assay
Antiproliferative activity against human SGC7901 cells measured after 72 hrs by MTT assay
|
[PMID: 27428395]
|
SGC-7901
|
IC50 |
0.028 μM
Compound: 1a, CA-4
|
Cytotoxicity against human SGC7901 cells assessed as cell growth inhibition after 72 hrs by MTT assay
Cytotoxicity against human SGC7901 cells assessed as cell growth inhibition after 72 hrs by MTT assay
|
[PMID: 25529737]
|
SGC-7901
|
IC50 |
0.028 μM
Compound: 1a, CA-4
|
Antiproliferative activity against human SGC7901 cells after 72 hrs by MTT assay
Antiproliferative activity against human SGC7901 cells after 72 hrs by MTT assay
|
[PMID: 25233100]
|
SGC-7901
|
IC50 |
0.13 μM
Compound: 1; CA-4
|
Antiproliferative activity against human SGC7901 cells measured after 72 hrs by MTT assay
Antiproliferative activity against human SGC7901 cells measured after 72 hrs by MTT assay
|
[PMID: 30901597]
|
SH-SY5Y
|
IC50 |
|
Cytotoxicity against SHSY5Y cell line by MTT assay
Cytotoxicity against SHSY5Y cell line by MTT assay
|
[PMID: 16913727]
|
SH-SY5Y
|
IC50 |
|
Cytotoxicity against human SH-SY5Y cells assessed as cell viability after 48 hrs by MTT assay
Cytotoxicity against human SH-SY5Y cells assessed as cell viability after 48 hrs by MTT assay
|
[PMID: 21696175]
|
SH-SY5Y
|
IC50 |
|
Cytotoxicity against human SH-SY5Y cells assessed as reduction in cell viability after 48 hrs by MTT assay
Cytotoxicity against human SH-SY5Y cells assessed as reduction in cell viability after 48 hrs by MTT assay
|
[PMID: 25584687]
|
SiHa
|
IC50 |
|
Cytotoxicity against human SiHa cells after 48 hrs by MTT assay
Cytotoxicity against human SiHa cells after 48 hrs by MTT assay
|
10.1039/C3MD00372H
|
SiHa
|
IC50 |
0.029 μM
Compound: 2; CA-4
|
Antiproliferation activity against human SiHa cells assessed as reduction in cell growth measured after 48 to 72 hrs by CCK-8 assay
Antiproliferation activity against human SiHa cells assessed as reduction in cell growth measured after 48 to 72 hrs by CCK-8 assay
|
[PMID: 35339837]
|
SiHa
|
IC50 |
0.029 μM
Compound: 2; CA-4
|
Antiproliferative activity against human SiHa cells assessed as reduction in cell growth measured after 48 to 72 hrs by CCK-8 assay
Antiproliferative activity against human SiHa cells assessed as reduction in cell growth measured after 48 to 72 hrs by CCK-8 assay
|
[PMID: 35339837]
|
SK-BR-3
|
IC50 |
|
Cytotoxicity against human SKBR3 cells assessed as cell viability after 72 hrs by resazurin reduction assay
Cytotoxicity against human SKBR3 cells assessed as cell viability after 72 hrs by resazurin reduction assay
|
[PMID: 26599530]
|
SK-BR-3
|
IC50 |
|
Cytotoxicity against human SK-BR3 cells assessed as [3H]thymidine incorporation after 72 hrs by microplate scintillation counter
Cytotoxicity against human SK-BR3 cells assessed as [3H]thymidine incorporation after 72 hrs by microplate scintillation counter
|
[PMID: 18396050]
|
SK-MEL-2
|
GI50 |
0.003 μM
Compound: 2, combretastatin A-4, CA-4, NSC 613729
|
Growth inhibition of human SK-MEL-2 cells after 48 hrs by SRB assay
Growth inhibition of human SK-MEL-2 cells after 48 hrs by SRB assay
|
[PMID: 22982122]
|
SK-MEL-2
|
GI50 |
0.004 μM
Compound: CA4, NSC 613729
|
Growth inhibition of human SK-MEL-2 cells after 48 hrs by SRB assay
Growth inhibition of human SK-MEL-2 cells after 48 hrs by SRB assay
|
[PMID: 24387982]
|
SK-MEL-2
|
GI50 |
0.004 μM
Compound: CA4; NSC 613729
|
Cytotoxicity against human SK-MEL-2 cells by SRB assay
Cytotoxicity against human SK-MEL-2 cells by SRB assay
|
[PMID: 26257861]
|
SK-MEL-2
|
GI50 |
|
Growth inhibition of human SK-MEL-2 cells after 48 hrs by sulforhodamine B assay
Growth inhibition of human SK-MEL-2 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 24388833]
|
SK-MEL-28
|
GI50 |
0.007 μM
Compound: 2, combretastatin A-4, CA-4, NSC 613729
|
Growth inhibition of human SK-MEL-28 cells after 48 hrs by SRB assay
Growth inhibition of human SK-MEL-28 cells after 48 hrs by SRB assay
|
[PMID: 22982122]
|
SK-MEL-28
|
GI50 |
0.008 μM
Compound: CA4, NSC 613729
|
Growth inhibition of human SK-MEL-28 cells after 48 hrs by SRB assay
Growth inhibition of human SK-MEL-28 cells after 48 hrs by SRB assay
|
[PMID: 24387982]
|
SK-MEL-28
|
GI50 |
0.008 μM
Compound: CA4; NSC 613729
|
Cytotoxicity against human SK-MEL-28 cells by SRB assay
Cytotoxicity against human SK-MEL-28 cells by SRB assay
|
[PMID: 26257861]
|
SK-MEL-28
|
GI50 |
|
Growth inhibition of human SK-MEL-28 cells after 48 hrs by sulforhodamine B assay
Growth inhibition of human SK-MEL-28 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 24388833]
|
SK-MEL-5
|
GI50 |
0.003 μM
Compound: 2, combretastatin A-4, CA-4, NSC 613729
|
Growth inhibition of human SK-MEL-5 cells after 48 hrs by SRB assay
Growth inhibition of human SK-MEL-5 cells after 48 hrs by SRB assay
|
[PMID: 22982122]
|
SK-MEL-5
|
GI50 |
|
Growth inhibition of human SK-MEL-5 cells after 48 hrs by sulforhodamine B assay
Growth inhibition of human SK-MEL-5 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 27031215]
|
SK-MEL-5
|
GI50 |
0.004 μM
Compound: CA4, NSC 613729
|
Growth inhibition of human SK-MEL-5 cells after 48 hrs by SRB assay
Growth inhibition of human SK-MEL-5 cells after 48 hrs by SRB assay
|
[PMID: 24387982]
|
SK-MEL-5
|
GI50 |
0.004 μM
Compound: CA4; NSC 613729
|
Cytotoxicity against human SK-MEL-5 cells by SRB assay
Cytotoxicity against human SK-MEL-5 cells by SRB assay
|
[PMID: 26257861]
|
SK-MEL-5
|
GI50 |
|
Growth inhibition of human SK-MEL-5 cells after 48 hrs by sulforhodamine B assay
Growth inhibition of human SK-MEL-5 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 24388833]
|
SK-OV-3
|
GI50 |
|
Growth inhibition of human SK-OV-3 after 48 hrs by SRB assay
Growth inhibition of human SK-OV-3 after 48 hrs by SRB assay
|
[PMID: 18722127]
|
SK-OV-3
|
GI50 |
0.00042 μM
Compound: 2, CA4
|
Cytotoxicity against human SKOV3 cells by SRB assay
Cytotoxicity against human SKOV3 cells by SRB assay
|
[PMID: 24016002]
|
SK-OV-3
|
GI50 |
|
Growth inhibition of human SKOV3 cells by sulforhodamine B assay
Growth inhibition of human SKOV3 cells by sulforhodamine B assay
|
[PMID: 23772309]
|
SK-OV-3
|
IC50 |
|
Growth inhibition of human SKOV3 cells by MTT assay
Growth inhibition of human SKOV3 cells by MTT assay
|
[PMID: 25689111]
|
SK-OV-3
|
IC50 |
0.0033 μM
Compound: 1, CA-4
|
Antiproliferative activity against human SKOV3 cells after 48 hrs by SRB assay
Antiproliferative activity against human SKOV3 cells after 48 hrs by SRB assay
|
[PMID: 19894742]
|
SK-OV-3
|
IC50 |
0.0035 μM
Compound: 1, CA-4
|
Antiproliferative activity against human SKOV3 cells expressing adenoviral MDR1 after 48 hrs by SRB assay
Antiproliferative activity against human SKOV3 cells expressing adenoviral MDR1 after 48 hrs by SRB assay
|
[PMID: 19894742]
|
SK-OV-3
|
GI50 |
|
Cytotoxicity against human SKOV3 cells assessed as growth inhibition measured after 48 hrs by SRB assay
Cytotoxicity against human SKOV3 cells assessed as growth inhibition measured after 48 hrs by SRB assay
|
[PMID: 31059248]
|
SK-OV-3
|
GI50 |
0.00455 μM
Compound: CA4, CA4P
|
Cytotoxicity against human SKOV3 cells after 48 hrs by SRB assay
Cytotoxicity against human SKOV3 cells after 48 hrs by SRB assay
|
[PMID: 24183586]
|
SK-OV-3
|
GI50 |
|
Cytotoxicity against human SKOV3 cells assessed as reduction in cell viability incubated for 48 hrs by SRB assay
Cytotoxicity against human SKOV3 cells assessed as reduction in cell viability incubated for 48 hrs by SRB assay
|
[PMID: 31534659]
|
SK-OV-3
|
GI50 |
|
Cytotoxicity against human SKOV3 cells after 48 hrs by SRB assay
Cytotoxicity against human SKOV3 cells after 48 hrs by SRB assay
|
[PMID: 23993969]
|
SK-OV-3
|
IC50 |
|
Antiproliferative activity against human SKOV3 cells after 72 hrs by CCK8 assay
Antiproliferative activity against human SKOV3 cells after 72 hrs by CCK8 assay
|
[PMID: 30006162]
|
SK-OV-3
|
IC50 |
0.012 μM
Compound: 1; CA-4
|
Antiproliferative activity against human SKOV3 cells after 48 hrs by MTT assay
Antiproliferative activity against human SKOV3 cells after 48 hrs by MTT assay
|
[PMID: 29306206]
|
SK-OV-3
|
GI50 |
0.059 μM
Compound: CA4, NSC 613729
|
Growth inhibition of human SKOV3 cells after 48 hrs by SRB assay
Growth inhibition of human SKOV3 cells after 48 hrs by SRB assay
|
[PMID: 24387982]
|
SK-OV-3
|
GI50 |
0.059 μM
Compound: CA4; NSC 613729
|
Cytotoxicity against human SKOV3 cells by SRB assay
Cytotoxicity against human SKOV3 cells by SRB assay
|
[PMID: 26257861]
|
SK-OV-3
|
GI50 |
0.063 μM
Compound: 2, combretastatin A-4, CA-4, NSC 613729
|
Growth inhibition of human SKOV3 cells after 48 hrs by SRB assay
Growth inhibition of human SKOV3 cells after 48 hrs by SRB assay
|
[PMID: 22982122]
|
SK-OV-3
|
IC50 |
0.38 μM
Compound: 1a; CA-4
|
Cytotoxicity against human SKOV3 cells after 48 hrs by MTT assay
Cytotoxicity against human SKOV3 cells after 48 hrs by MTT assay
|
[PMID: 29291446]
|
SK-OV-3
|
IC50 |
|
Antiproliferative activity against human SK-OV-3 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
Antiproliferative activity against human SK-OV-3 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
|
[PMID: 36252396]
|
SK-OV-3
|
EC50 |
1.2 nM
Compound: 5, (Z)-5, CA-4, Combretastatin A-4
|
Cytotoxicity against human SKOV3 cells assessed as cell viability after 48 hrs by MTS assay
Cytotoxicity against human SKOV3 cells assessed as cell viability after 48 hrs by MTS assay
|
10.1039/C0MD00095G
|
SK-OV-3
|
IC50 |
1.7 nM
Compound: 1, CA-4, combretastatin
|
Cytotoxicity against human SKOV3 cells after 48 hrs by MTS assay
Cytotoxicity against human SKOV3 cells after 48 hrs by MTS assay
|
[PMID: 22304851]
|
SK-OV-3
|
IC50 |
|
Growth inhibition of human SKOV3 cells after 48 hrs by SRB assay
Growth inhibition of human SKOV3 cells after 48 hrs by SRB assay
|
[PMID: 24900453]
|
SK-OV-3
|
IC50 |
|
Inhibition of MDR1 (unknown origin) transfected in human SKOV3 cells assessed as growth inhibition after 48 hrs by SRB assay
Inhibition of MDR1 (unknown origin) transfected in human SKOV3 cells assessed as growth inhibition after 48 hrs by SRB assay
|
[PMID: 23332369]
|
SK-OV-3
|
IC50 |
|
Cytotoxicity against human SKOV3 cells expressing MDR1 after 72 hrs by MTS assay
Cytotoxicity against human SKOV3 cells expressing MDR1 after 72 hrs by MTS assay
|
[PMID: 24087857]
|
SK-OV-3
|
EC50 |
3.1 nM
Compound: 5, (Z)-5, CA-4, Combretastatin A-4
|
Cytotoxicity against taxol-resistant human SKOV3 cells assessed as cell viability after 48 hrs by MTS assay
Cytotoxicity against taxol-resistant human SKOV3 cells assessed as cell viability after 48 hrs by MTS assay
|
10.1039/C0MD00095G
|
SK-OV-3
|
GI50 |
31.6 μM
Compound: 1; CA-4
|
Antiproliferative activity against human SK-OV-3 cells assessed as cell growth inhibition measured after 48 hrs by SRB assay
Antiproliferative activity against human SK-OV-3 cells assessed as cell growth inhibition measured after 48 hrs by SRB assay
|
[PMID: 27161282]
|
SK-OV-3
|
IC50 |
|
Growth inhibition of paclitaxel-resistant human SKOV3 cells after 48 hrs by SRB assay
Growth inhibition of paclitaxel-resistant human SKOV3 cells after 48 hrs by SRB assay
|
[PMID: 24900453]
|
SK-OV-3
|
IC50 |
|
Antiproliferative activity against human SK-OV-3 cells assessed as decrease in cell growth measured after 48 hrs by SRB method
Antiproliferative activity against human SK-OV-3 cells assessed as decrease in cell growth measured after 48 hrs by SRB method
|
[PMID: 33310545]
|
SK-OV-3
|
IC50 |
|
Antiproliferative activity against human SKOV3 cells after 48 hrs by SRB assay
Antiproliferative activity against human SKOV3 cells after 48 hrs by SRB assay
|
[PMID: 23895532]
|
SK-OV-3
|
IC50 |
|
Antiproliferative activity against human SKOV3 cells by SRB assay
Antiproliferative activity against human SKOV3 cells by SRB assay
|
[PMID: 29655610]
|
SK-OV-3
|
GI50 |
|
Cytotoxicity against human SKOV3 cells assessed as growth inhibition after 48 hrs by SRB assay
Cytotoxicity against human SKOV3 cells assessed as growth inhibition after 48 hrs by SRB assay
|
[PMID: 26852340]
|
SK-OV-3
|
IC50 |
|
Antiproliferative activity against human SKOV3 after 48 hrs by spectrophotometry
Antiproliferative activity against human SKOV3 after 48 hrs by spectrophotometry
|
[PMID: 21774499]
|
SK-OV-3
|
IC50 |
|
Cytotoxicity against human SKOV3 cells assessed as growth inhibition after 48 hrs by SRB assay
Cytotoxicity against human SKOV3 cells assessed as growth inhibition after 48 hrs by SRB assay
|
[PMID: 27213719]
|
SK-OV-3
|
IC50 |
|
Antiproliferative activity against wild type human SK-OV-3 cells assessed as inhibition of cell growth by SRB assay
Antiproliferative activity against wild type human SK-OV-3 cells assessed as inhibition of cell growth by SRB assay
|
[PMID: 36889150]
|
SK-OV-3
|
IC50 |
|
Antiproliferative activity against human SKOV3 cells after 48 hrs by sulforhodamine B assay
Antiproliferative activity against human SKOV3 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 30297118]
|
SK-OV-3
|
IC50 |
|
Antiproliferative activity against human SKOV3 cells after 72 hrs by sulforhodamine B assay
Antiproliferative activity against human SKOV3 cells after 72 hrs by sulforhodamine B assay
|
[PMID: 30098869]
|
SK-OV-3
|
IC50 |
|
Cytotoxicity against human SK-OV-3 cells assessed as reduction in cell viability by Sulforhodamine B assay
Cytotoxicity against human SK-OV-3 cells assessed as reduction in cell viability by Sulforhodamine B assay
|
[PMID: 33647840]
|
SK-OV-3
|
GI50 |
|
Growth inhibition of human SKOV3 cells after 48 hrs by sulforhodamine B assay
Growth inhibition of human SKOV3 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 24388833]
|
SK-OV-3
|
IC50 |
|
Antiproliferative activity against human SK-OV-3 cells after 72 hrs by CellTiter Glo assay
Antiproliferative activity against human SK-OV-3 cells after 72 hrs by CellTiter Glo assay
|
[PMID: 35797900]
|
SK-OV-3
|
IC50 |
|
Cytotoxicity against human SKOV3 cells after 72 hrs by MTS assay
Cytotoxicity against human SKOV3 cells after 72 hrs by MTS assay
|
[PMID: 24087857]
|
SK-OV-3
|
IC50 |
|
Antiproliferative activity against human SKOV3 cells overexpressing wild type beta3 tubulin after 48 hrs by sulforhodamine B assay
Antiproliferative activity against human SKOV3 cells overexpressing wild type beta3 tubulin after 48 hrs by sulforhodamine B assay
|
[PMID: 25882519]
|
SK-OV-3
|
IC50 |
|
Antiproliferative activity against multidrug resistant human SKOV3 cells expressing MDR1-M6/6 after 48 hrs by SRB assay
Antiproliferative activity against multidrug resistant human SKOV3 cells expressing MDR1-M6/6 after 48 hrs by SRB assay
|
[PMID: 27213719]
|
SK-OV-3
|
IC50 |
|
Antiproliferative activity against human SK-OV-3 cells overexpressing MDR-1-M6/6 assessed as inhibition of cell growth by SRB assay
Antiproliferative activity against human SK-OV-3 cells overexpressing MDR-1-M6/6 assessed as inhibition of cell growth by SRB assay
|
[PMID: 36889150]
|
SK-OV-3
|
IC50 |
|
Cytotoxicity against human SK-OV-3 cells over expressing MDR1-6/6 assessed as reduction in cell viability by Sulforhodamine B assay
Cytotoxicity against human SK-OV-3 cells over expressing MDR1-6/6 assessed as reduction in cell viability by Sulforhodamine B assay
|
[PMID: 33647840]
|
SK-OV-3
|
IC50 |
|
Cytotoxicity against human SKOV3 cells assessed as growth inhibition after 48 hrs by SRB assay
Cytotoxicity against human SKOV3 cells assessed as growth inhibition after 48 hrs by SRB assay
|
[PMID: 23332369]
|
SMMC-7721
|
IC50 |
|
Antiproliferative activity against human SMMC7721 cells after 72 hrs by MTT assay
Antiproliferative activity against human SMMC7721 cells after 72 hrs by MTT assay
|
[PMID: 29172084]
|
SMMC-7721
|
IC50 |
|
Cytotoxicity against human SMMC7721 cells assessed as growth inhibition after 72 hrs by MTT assay
Cytotoxicity against human SMMC7721 cells assessed as growth inhibition after 72 hrs by MTT assay
|
[PMID: 23708012]
|
SMMC-7721
|
IC50 |
|
Anticancer activity against human SMMC7721 cells after 72 hrs
Anticancer activity against human SMMC7721 cells after 72 hrs
|
[PMID: 19713108]
|
SMMC-7721
|
IC50 |
|
Antiproliferative activity against human SMMC7721 cells after 72 hrs by MTT assay
Antiproliferative activity against human SMMC7721 cells after 72 hrs by MTT assay
|
[PMID: 29407949]
|
SMMC-7721
|
IC50 |
|
Cytotoxicity against human SMMC7721 cells after 72 hrs by MTT assay
Cytotoxicity against human SMMC7721 cells after 72 hrs by MTT assay
|
[PMID: 28622907]
|
SMMC-7721
|
IC50 |
|
Cytotoxicity against human SMMC7721 cells after 48 hrs by MTT assay
Cytotoxicity against human SMMC7721 cells after 48 hrs by MTT assay
|
[PMID: 19665898]
|
SN12C
|
GI50 |
0.006 μM
Compound: CA4, NSC 613729
|
Growth inhibition of human SN12C cells after 48 hrs by SRB assay
Growth inhibition of human SN12C cells after 48 hrs by SRB assay
|
[PMID: 24387982]
|
SN12C
|
GI50 |
0.006 μM
Compound: 2, combretastatin A-4, CA-4, NSC 613729
|
Growth inhibition of human SN12C cells after 48 hrs by SRB assay
Growth inhibition of human SN12C cells after 48 hrs by SRB assay
|
[PMID: 22982122]
|
SN12C
|
GI50 |
|
Growth inhibition of human SN12C cells after 48 hrs by sulforhodamine B assay
Growth inhibition of human SN12C cells after 48 hrs by sulforhodamine B assay
|
[PMID: 24388833]
|
SNB-19
|
GI50 |
0.003 μM
Compound: 2, combretastatin A-4, CA-4, NSC 613729
|
Growth inhibition of human SNB19 cells after 48 hrs by SRB assay
Growth inhibition of human SNB19 cells after 48 hrs by SRB assay
|
[PMID: 22982122]
|
SNB-19
|
GI50 |
0.004 μM
Compound: CA4, NSC 613729
|
Growth inhibition of human SNB19 cells after 48 hrs by SRB assay
Growth inhibition of human SNB19 cells after 48 hrs by SRB assay
|
[PMID: 24387982]
|
SNB-19
|
GI50 |
0.004 μM
Compound: CA4; NSC 613729
|
Cytotoxicity against human SNB19 cells by SRB assay
Cytotoxicity against human SNB19 cells by SRB assay
|
[PMID: 26257861]
|
SNB-19
|
GI50 |
|
Growth inhibition of human SNB19 cells after 48 hrs by sulforhodamine B assay
Growth inhibition of human SNB19 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 24388833]
|
SNB-75
|
GI50 |
0.007 μM
Compound: 2, combretastatin A-4, CA-4, NSC 613729
|
Growth inhibition of human SNB75 cells after 48 hrs by SRB assay
Growth inhibition of human SNB75 cells after 48 hrs by SRB assay
|
[PMID: 22982122]
|
SNB-75
|
GI50 |
0.008 μM
Compound: CA4, NSC 613729
|
Growth inhibition of human SNB75 cells after 48 hrs by SRB assay
Growth inhibition of human SNB75 cells after 48 hrs by SRB assay
|
[PMID: 24387982]
|
SNB-75
|
GI50 |
0.008 μM
Compound: CA4; NSC 613729
|
Cytotoxicity against human SNB75 cells by SRB assay
Cytotoxicity against human SNB75 cells by SRB assay
|
[PMID: 26257861]
|
SNB-75
|
GI50 |
|
Growth inhibition of human SNB75 cells after 48 hrs by sulforhodamine B assay
Growth inhibition of human SNB75 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 27031215]
|
SNB-75
|
GI50 |
|
Growth inhibition of human SNB75 cells after 48 hrs by sulforhodamine B assay
Growth inhibition of human SNB75 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 24388833]
|
SNU-423
|
IC50 |
|
Cytotoxicity against human SNU423 cells after 48 hrs by alamar blue assay
Cytotoxicity against human SNU423 cells after 48 hrs by alamar blue assay
|
[PMID: 19117761]
|
SR
|
GI50 |
0.003 μM
Compound: CA4, NSC 613729
|
Growth inhibition of human SR cells after 48 hrs by SRB assay
Growth inhibition of human SR cells after 48 hrs by SRB assay
|
[PMID: 24387982]
|
SR
|
GI50 |
0.003 μM
Compound: 2, combretastatin A-4, CA-4, NSC 613729
|
Growth inhibition of human SR cells after 48 hrs by SRB assay
Growth inhibition of human SR cells after 48 hrs by SRB assay
|
[PMID: 22982122]
|
SR
|
GI50 |
0.003 μM
Compound: CA4; NSC 613729
|
Cytotoxicity against human SR cells by SRB assay
Cytotoxicity against human SR cells by SRB assay
|
[PMID: 26257861]
|
SR
|
GI50 |
|
Growth inhibition of human SR cells after 48 hrs by sulforhodamine B assay
Growth inhibition of human SR cells after 48 hrs by sulforhodamine B assay
|
[PMID: 27031215]
|
SR
|
GI50 |
|
Growth inhibition of human SR cells after 48 hrs by sulforhodamine B assay
Growth inhibition of human SR cells after 48 hrs by sulforhodamine B assay
|
[PMID: 24388833]
|
SW1990
|
IC50 |
|
Cytotoxicity against human SW1990 cells assessed as growth inhibition after 72 hrs by MTT assay
Cytotoxicity against human SW1990 cells assessed as growth inhibition after 72 hrs by MTT assay
|
[PMID: 23708012]
|
SW1990
|
IC50 |
|
Anticancer activity against human SW1990 cells after 72 hrs
Anticancer activity against human SW1990 cells after 72 hrs
|
[PMID: 19713108]
|
SW48
|
IC50 |
|
Antiproliferative activity in human SW48 cells assessed as cell viability after 72 hrs by MTT assay
Antiproliferative activity in human SW48 cells assessed as cell viability after 72 hrs by MTT assay
|
[PMID: 22329561]
|
SW480
|
IC50 |
|
Cytotoxicity against human SW480 cells after 48 hrs by MTT assay
Cytotoxicity against human SW480 cells after 48 hrs by MTT assay
|
[PMID: 23356786]
|
SW480
|
IC50 |
|
Antiproliferative activity in human SW480 cells assessed as cell viability after 72 hrs by MTT assay
Antiproliferative activity in human SW480 cells assessed as cell viability after 72 hrs by MTT assay
|
[PMID: 22329561]
|
SW-620
|
IC50 |
|
Antiproliferative activity against human SW620 cells measured after 48 hrs by MTT assay
Antiproliferative activity against human SW620 cells measured after 48 hrs by MTT assay
|
[PMID: 36150341]
|
SW-620
|
GI50 |
0.003 μM
Compound: CA4, NSC 613729
|
Growth inhibition of human SW620 cells after 48 hrs by SRB assay
Growth inhibition of human SW620 cells after 48 hrs by SRB assay
|
[PMID: 24387982]
|
SW-620
|
GI50 |
0.003 μM
Compound: 2, combretastatin A-4, CA-4, NSC 613729
|
Growth inhibition of human SW620 cells after 48 hrs by SRB assay
Growth inhibition of human SW620 cells after 48 hrs by SRB assay
|
[PMID: 22982122]
|
SW-620
|
GI50 |
0.003 μM
Compound: CA4; NSC 613729
|
Cytotoxicity against human SW620 cells by SRB assay
Cytotoxicity against human SW620 cells by SRB assay
|
[PMID: 26257861]
|
SW-620
|
IC50 |
0.023 μM
Compound: CA-4, 1a
|
Cytotoxicity against human SW620 cells after 72 hrs by MTT assay
Cytotoxicity against human SW620 cells after 72 hrs by MTT assay
|
[PMID: 20338766]
|
SW-620
|
IC50 |
|
Antiproliferative activity in human SW620 cells assessed as cell viability after 72 hrs by MTT assay
Antiproliferative activity in human SW620 cells assessed as cell viability after 72 hrs by MTT assay
|
[PMID: 22329561]
|
SW-620
|
GI50 |
|
Growth inhibition of human SW620 cells after 48 hrs by sulforhodamine B assay
Growth inhibition of human SW620 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 24388833]
|
T-24
|
IC50 |
0.0087 μM
Compound: CA-4, 1a
|
Cytotoxicity against human T24 cells after 72 hrs by MTT assay
Cytotoxicity against human T24 cells after 72 hrs by MTT assay
|
[PMID: 20338766]
|
T47D
|
IC50 |
|
Antiproliferative activity against human T47D cells measured after 48 hrs by MTT assay
Antiproliferative activity against human T47D cells measured after 48 hrs by MTT assay
|
[PMID: 32717486]
|
T47D
|
IC50 |
0.021 μM
Compound: 2; CA-4
|
Antiproliferative activity against human T47D cells assessed as inhibition of cell growth measured after 48 hrs by MTT assay
Antiproliferative activity against human T47D cells assessed as inhibition of cell growth measured after 48 hrs by MTT assay
|
[PMID: 36334455]
|
T47D
|
IC50 |
|
Antiproliferative activity against human T47D cells assessed as cell growth inhibition after 48 hrs by MTT assay
Antiproliferative activity against human T47D cells assessed as cell growth inhibition after 48 hrs by MTT assay
|
[PMID: 33895499]
|
T47D
|
IC50 |
|
Cytotoxicity against human T47D cells after 72 hrs by MTT assay
Cytotoxicity against human T47D cells after 72 hrs by MTT assay
|
[PMID: 30472600]
|
T47D
|
GI50 |
10 μM
Compound: 2, combretastatin A-4, CA-4, NSC 613729
|
Growth inhibition of human T47D cells after 48 hrs by SRB assay
Growth inhibition of human T47D cells after 48 hrs by SRB assay
|
[PMID: 22982122]
|
T47D
|
IC50 |
|
Antiproliferative activity against human T47D cells assessed as reduction in cell viability after 72 hrs by MTT assay
Antiproliferative activity against human T47D cells assessed as reduction in cell viability after 72 hrs by MTT assay
|
[PMID: 31610372]
|
T84
|
IC50 |
|
Antiproliferative activity in human T84 cells assessed as cell viability after 72 hrs by MTT assay
Antiproliferative activity in human T84 cells assessed as cell viability after 72 hrs by MTT assay
|
[PMID: 22329561]
|
T98G
|
IC50 |
|
Cytotoxicity against human T98G cells assessed as cell viability after 72 hrs by resazurin reduction assay
Cytotoxicity against human T98G cells assessed as cell viability after 72 hrs by resazurin reduction assay
|
[PMID: 26599530]
|
TK-10
|
GI50 |
0.1 μM
Compound: CA4, NSC 613729
|
Growth inhibition of human TK10 cells after 48 hrs by SRB assay
Growth inhibition of human TK10 cells after 48 hrs by SRB assay
|
[PMID: 24387982]
|
TK-10
|
GI50 |
0.1 μM
Compound: 2, combretastatin A-4, CA-4, NSC 613729
|
Growth inhibition of human TK10 cells after 48 hrs by SRB assay
Growth inhibition of human TK10 cells after 48 hrs by SRB assay
|
[PMID: 22982122]
|
TK-10
|
GI50 |
|
Growth inhibition of human TK10 cells after 48 hrs by sulforhodamine B assay
Growth inhibition of human TK10 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 24388833]
|
TSGH 9201
|
IC50 |
|
Antiproliferative activity against human TSGH stomach carcinoma cell line by methylene blue dye assay
Antiproliferative activity against human TSGH stomach carcinoma cell line by methylene blue dye assay
|
[PMID: 17034147]
|
U-251
|
GI50 |
0.004 μM
Compound: CA4, NSC 613729
|
Growth inhibition of human U251 cells after 48 hrs by SRB assay
Growth inhibition of human U251 cells after 48 hrs by SRB assay
|
[PMID: 24387982]
|
U-251
|
GI50 |
0.004 μM
Compound: CA4; NSC 613729
|
Cytotoxicity against human U251 cells by SRB assay
Cytotoxicity against human U251 cells by SRB assay
|
[PMID: 26257861]
|
U-251
|
GI50 |
|
Growth inhibition of human U251 cells after 48 hrs by sulforhodamine B assay
Growth inhibition of human U251 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 27031215]
|
U-251
|
GI50 |
0.007 μM
Compound: 2, combretastatin A-4, CA-4, NSC 613729
|
Growth inhibition of human U251cells after 48 hrs by SRB assay
Growth inhibition of human U251cells after 48 hrs by SRB assay
|
[PMID: 22982122]
|
U-251
|
IC50 |
|
Antiproliferative activity against human U-251 cells measured after 48 hrs by MTT assay
Antiproliferative activity against human U-251 cells measured after 48 hrs by MTT assay
|
[PMID: 36150341]
|
U-251
|
IC50 |
|
Antiproliferative activity against human U-251 cells after 48 hrs by MTT assay
Antiproliferative activity against human U-251 cells after 48 hrs by MTT assay
|
[PMID: 34311158]
|
U-251
|
GI50 |
|
Antiproliferative activity against human U251 cells incubated for 48 hrs by MTT assay
Antiproliferative activity against human U251 cells incubated for 48 hrs by MTT assay
|
[PMID: 32832031]
|
U-251
|
IC50 |
|
Antiproliferative activity against human U251 cells after 24 to 48 hrs by CKK8 assay
Antiproliferative activity against human U251 cells after 24 to 48 hrs by CKK8 assay
|
[PMID: 25105922]
|
U-251
|
GI50 |
|
Growth inhibition of human U251 cells after 48 hrs by sulforhodamine B assay
Growth inhibition of human U251 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 24388833]
|
U2OS
|
IC50 |
0.0141 μM
Compound: 3, CA4
|
Anticancer activity against human U2OS cells assessed as reduction in cell proliferation after 48 hrs by WST-1 assay
Anticancer activity against human U2OS cells assessed as reduction in cell proliferation after 48 hrs by WST-1 assay
|
[PMID: 25466200]
|
U2OS
|
IC50 |
0.766 nM
Compound: 7; CA-4
|
Cytotoxicity against human U2OS cells assessed as reduction in cell viability incubated for 72 hrs by MTS assay
Cytotoxicity against human U2OS cells assessed as reduction in cell viability incubated for 72 hrs by MTS assay
|
[PMID: 31401010]
|
U-87MG ATCC
|
IC50 |
|
Antiproliferative activity against human U-87 MG cells measured after 48 hrs by MTT assay
Antiproliferative activity against human U-87 MG cells measured after 48 hrs by MTT assay
|
[PMID: 36150341]
|
U-87MG ATCC
|
IC50 |
|
Antiproliferative activity against human U87 cells assessed as reduction in cell growth measured after 72 hrs by MTT assay
Antiproliferative activity against human U87 cells assessed as reduction in cell growth measured after 72 hrs by MTT assay
|
[PMID: 31830637]
|
U-87MG ATCC
|
IC50 |
|
Antiproliferative activity against human U87MG after 48 hrs by spectrophotometry
Antiproliferative activity against human U87MG after 48 hrs by spectrophotometry
|
[PMID: 21774499]
|
U-87MG ATCC
|
IC50 |
|
Antiproliferative activity against human U87 cells after 72 hrs by resazurin-based fluorescence assay
Antiproliferative activity against human U87 cells after 72 hrs by resazurin-based fluorescence assay
|
[PMID: 29202409]
|
U-87MG ATCC
|
IC50 |
|
Antiproliferative activity against human U87MG cells after 72 hrs by MTS assay
Antiproliferative activity against human U87MG cells after 72 hrs by MTS assay
|
[PMID: 30525602]
|
U-87MG ATCC
|
IC50 |
9.75 μM
Compound: CA-4; B
|
Antiproliferative activity against human U87 cells after 48 hrs by MTT assay
Antiproliferative activity against human U87 cells after 48 hrs by MTT assay
|
[PMID: 28774575]
|
U-937
|
IC50 |
|
Inhibition of human PDE4 expressed in U937 cells using [3H]cAMP as substrate after 30 mins
Inhibition of human PDE4 expressed in U937 cells using [3H]cAMP as substrate after 30 mins
|
[PMID: 21955454]
|
U-937
|
IC50 |
0.001 μM
Compound: 8; CA-4
|
Antiproliferative activity against human U-937 cells assessed as cell growth inhibition after 72 hrs by CCK8 assay
Antiproliferative activity against human U-937 cells assessed as cell growth inhibition after 72 hrs by CCK8 assay
|
[PMID: 34454126]
|
UACC-257
|
GI50 |
0.003 μM
Compound: CA4, NSC 613729
|
Growth inhibition of human UACC257 cells after 48 hrs by SRB assay
Growth inhibition of human UACC257 cells after 48 hrs by SRB assay
|
[PMID: 24387982]
|
UACC-257
|
GI50 |
0.003 μM
Compound: 2, combretastatin A-4, CA-4, NSC 613729
|
Growth inhibition of human UACC257 cells after 48 hrs by SRB assay
Growth inhibition of human UACC257 cells after 48 hrs by SRB assay
|
[PMID: 22982122]
|
UACC-257
|
GI50 |
|
Growth inhibition of human UACC257 cells after 48 hrs by sulforhodamine B assay
Growth inhibition of human UACC257 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 24388833]
|
UACC-62
|
GI50 |
0.005 μM
Compound: 2, combretastatin A-4, CA-4, NSC 613729
|
Growth inhibition of human UACC62 cells after 48 hrs by SRB assay
Growth inhibition of human UACC62 cells after 48 hrs by SRB assay
|
[PMID: 22982122]
|
UACC-62
|
GI50 |
0.006 μM
Compound: CA4, NSC 613729
|
Growth inhibition of human UACC62 cells after 48 hrs by SRB assay
Growth inhibition of human UACC62 cells after 48 hrs by SRB assay
|
[PMID: 24387982]
|
UACC-62
|
GI50 |
0.006 μM
Compound: CA4; NSC 613729
|
Cytotoxicity against human UACC62 cells by SRB assay
Cytotoxicity against human UACC62 cells by SRB assay
|
[PMID: 26257861]
|
UACC-62
|
GI50 |
|
Growth inhibition of human UACC62 cells after 48 hrs by sulforhodamine B assay
Growth inhibition of human UACC62 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 24388833]
|
UO-31
|
GI50 |
0.019 μM
Compound: CA4, NSC 613729
|
Growth inhibition of human UO31 cells after 48 hrs by SRB assay
Growth inhibition of human UO31 cells after 48 hrs by SRB assay
|
[PMID: 24387982]
|
UO-31
|
GI50 |
0.019 μM
Compound: 2, combretastatin A-4, CA-4, NSC 613729
|
Growth inhibition of human UO31 cells after 48 hrs by SRB assay
Growth inhibition of human UO31 cells after 48 hrs by SRB assay
|
[PMID: 22982122]
|
UO-31
|
GI50 |
0.019 μM
Compound: CA4; NSC 613729
|
Cytotoxicity against human UO31 cells by SRB assay
Cytotoxicity against human UO31 cells by SRB assay
|
[PMID: 26257861]
|
UO-31
|
GI50 |
|
Growth inhibition of human UO31 cells after 48 hrs by sulforhodamine B assay
Growth inhibition of human UO31 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 24388833]
|
WI-38
|
IC50 |
31.57 μM
Compound: 1; CA-4
|
Cytotoxicity against human WI-38 cells assessed as reduction in cell growth incubated for 72 hrs by MTT assay
Cytotoxicity against human WI-38 cells assessed as reduction in cell growth incubated for 72 hrs by MTT assay
|
[PMID: 33421913]
|