2. JAK/STAT Signaling Protein Tyrosine Kinase/RTK
  3. EGFR
  4. BIBX 1382 dihydrochloride

BIBX 1382 dihydrochloride 是一种 ErbB 激酶抑制剂，有显著的抗病毒活性。BIBX 1382 主要通过抑制 ErbB 激酶家族成员来能影响病毒进入宿主细胞的能力。可用于对病毒与宿主之间的相互作用机制以及对高致病性病毒广谱干预的研究。

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BIBX 1382 dihydrochloride Chemical Structure

BIBX 1382 dihydrochloride Chemical Structure

CAS No. : 1216920-18-1

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BIBX 1382 dihydrochloride 的其他形式现货产品:

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BIBX 1382 dihydrochloride 相关抗体

Top Publications Citing Use of Products

    BIBX 1382 dihydrochloride purchased from MCE. Usage Cited in: Neuroscience. 2015 Jul 20;304:109-121.  [Abstract]

    GluN2B Y1472 phosphorylation in whole-cell lysate is increased after 5 and 10 min of EGF treatment in cultured neurons which could be blocked by BIBX-1382. EGFR activation increases SFK activity and phosphorylation of GluN2B Y1472. (A) Representative Western blot result of whole lysate samples from hippocampal slices treated with 50 ng/mL EGF incubation for 10 min. (B) Western blot of EGFR-treated DIV14 cultured hippocampal neurons with minimum glia composition shows increased phosphorylation of

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    • 生物活性

    • 纯度 & 产品资料

    • 参考文献

    生物活性

    BIBX 1382 dihydrochloride is an ErbB kinase inhibitor with significant antiviral activity. BIBX 1382 affects the ability of viruses to enter host cells by inhibiting members of the ErbB kinase family. It can be used to study the interaction mechanism between virus and host and the broad spectrum intervention of highly pathogenic viruses[1].

    分子量

    460.76

    Formula

    C18H21Cl3FN7
    CAS 号
    运输条件

    Room temperature in continental US; may vary elsewhere.
    储存方式

    Please store the product under the recommended conditions in the Certificate of Analysis.
    纯度 & 产品资料
    参考文献

    BIBX 1382 dihydrochloride 相关分类

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    • 稀释计算器

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    • Do most proteins show cross-species activity?

      Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

    Keywords:

    BIBX 13821216920-18-1BIBX1382BIBX-1382EGFREpidermal growth factor receptorErbB-1HER1Antiviral activitykinase inhibitorErbBInhibitorinhibitorinhibit

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    目录号：
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