2. GPCR/G Protein Neuronal Signaling
  3. mGluR
  4. Desmethyl-YM-298198 hydrochloride

Desmethyl-YM-298198 hydrochloride 

目录号: HY-103567
产品使用指南

摩尔计算器

Desmethyl-YM-298198 Hydrochloride 是一种高亲和力、选择性、非竞争性 mGluR1 拮抗剂 (IC50: 16 nM)。Desmethyl-YM-298198 Hydrochloride 对 Streptozotocin (HY-13753) 诱导的痛觉过敏小鼠具有镇痛作用。

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Desmethyl-YM-298198 hydrochloride Chemical Structure

Desmethyl-YM-298198 hydrochloride Chemical Structure

CAS No. : 1177767-57-5

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Desmethyl-YM-298198 hydrochloride 相关抗体

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Desmethyl-YM-298198 hydrochloride is a high-affinity, selective, and noncompetitive mGluR1 antagonist (IC50: 16 nM). Desmethyl-YM-298198 hydrochloride has analgesic effect in Streptozotocin (HY-13753)-induced hyperalgesic mice[1].

IC50 & Target

16 nM (mGluR1)[1]
分子量

364.89

Formula

C17H21ClN4OS
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Desmethyl-YM-298198 hydrochloride 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Desmethyl-YM-2981981177767-57-5mGluRMetabotropic glutamate receptorsanalgesicStreptozotocinhyperalgesicneurological disorderInhibitorinhibitorinhibit

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