2. PROTAC Apoptosis Autophagy
  3. Autophagy Apoptosis Ligands for E3 Ligase
  4. tDHU, acid

tDHU, acid 是一种二氢嘧啶类 cereblon 配体，包含 E3 连接酶配体和苯甲酸连接子。tDHU, acid 可作为 E3 泛素连接酶配体-Linker 偶联物，用于 PROTACs 的开发。

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tDHU, acid Chemical Structure

tDHU, acid Chemical Structure

CAS No. : 2377643-37-1

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tDHU, acid 相关抗体

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von Hippel-Lindau (VHL) MDM2 Cereblon IAP

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

tDHU, acid is a dihydropyrimidinecereblon ligand that contains an E3 ligase ligand and a benzoic acid linker. tDHU, acid can be used as an E3 ubiquitin ligase ligand-Linker conjugate for the development of PROTACs[1].

IC50 & Target

cereblon[1]
分子量

248.23

Formula

C12H12N2O4
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

tDHU, acid 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

tDHU, acid2377643-37-1AutophagyApoptosisLigands for E3 LigaseE3 ligase-recruiting MoietyDihydropyrimidineE3 ligase ligandbenzoic acidInhibitorinhibitorinhibit

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