2. Metabolic Enzyme/Protease
  3. Tyrosinase Endogenous Metabolite
  4. β-Sitostenone

β-Sitostenone  (Synonyms: Δ4-Sitosterol-3-one; β-Rosasterol oxide)

目录号: HY-N1238 纯度: ≥95.0%
COA 产品使用指南

摩尔计算器

β-Sitostenone 是一种从 Cochlospermum vitifolium 中分离得到的甾醇。β-Sitostenone 可抑制酪氨酸酶 (tyrosinase) 活性，并具有抗黑色素生成和抗肿瘤活性。

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β-Sitostenone Chemical Structure

β-Sitostenone Chemical Structure

CAS No. : 1058-61-3

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规格 价格 是否有货 数量
1 mg ￥800
In-stock
5 mg ￥2400
In-stock
10 mg   询价  
50 mg   询价  

* Please select Quantity before adding items.

β-Sitostenone 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

β-Sitostenone is a sterols that can be isolated from Cochlospermum vitifolium.β-Sitostenone inhibits tyrosinase activity, and has anti-melanogenic and anti-tumor activities[1][2][3].

IC50 & Target

Human Endogenous Metabolite

 

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
COLO 205 IC50
> 10 μM
Compound: 3
Cytotoxicity against human COLO205 cells after 24 hrs by MTT assay
Cytotoxicity against human COLO205 cells after 24 hrs by MTT assay
[PMID: 30199257]
COLO 320 IC50
> 10 μM
Compound: 3
Cytotoxicity against human COLO320 cells after 24 hrs by MTT assay
Cytotoxicity against human COLO320 cells after 24 hrs by MTT assay
[PMID: 30199257]
L5178Y IC50
> 10 μM
Compound: 3
Antiproliferative activity against mouse L5178Y cells after 72 hrs by MTT assay
Antiproliferative activity against mouse L5178Y cells after 72 hrs by MTT assay
[PMID: 30199257]
L5178Y IC50
> 10 μM
Compound: 3
Antiproliferative activity against mouse L5178Y cells harboring human ABCB1 after 72 hrs by MTT assay
Antiproliferative activity against mouse L5178Y cells harboring human ABCB1 after 72 hrs by MTT assay
[PMID: 30199257]
MRC5 IC50
> 10 μM
Compound: 3
Cytotoxicity against human MRC5 cells after 24 hrs by MTT assay
Cytotoxicity against human MRC5 cells after 24 hrs by MTT assay
[PMID: 30199257]
NIH3T3 IC50
> 10 μM
Compound: 3
Cytotoxicity against mouse NIH/3T3 cells after 24 hrs by MTT assay
Cytotoxicity against mouse NIH/3T3 cells after 24 hrs by MTT assay
[PMID: 30199257]
分子量

412.69

Formula

C29H48O
CAS 号
性状

固体

颜色

White to off-white

结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

溶解性数据
细胞实验： 

DMSO 中的溶解度 : 2.5 mg/mL (6.06 mM; 超声助溶 (<60°C); 吸湿的 DMSO 对产品的溶解度有显著影响，请使用新开封的 DMSO)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 2.4231 mL 12.1156 mL 24.2313 mL
5 mM 0.4846 mL 2.4231 mL 4.8463 mL
查看完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)。-80°C储存时，请在6个月内使用，-20°C储存时，请在1个月内使用。

  • 摩尔计算器

  • 稀释计算器

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量
=
浓度
×
体积
×
分子量 *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start)

C1

×
体积 (start)

V1

=
浓度 (final)

C2

×
体积 (final)

V2

动物溶解方案计算器
请输入动物实验的基本信息：

给药剂量

mg/kg

动物的平均体重

g

每只动物的给药体积

μL

动物数量

只
由于实验过程有损耗，建议您多配一只动物的量
计算结果
工作液所需浓度 : mg/mL
纯度 & 产品资料
参考文献

β-Sitostenone 相关分类

完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)。-80°C储存时，请在6个月内使用，-20°C储存时，请在1个月内使用。

可选溶剂 浓度 溶剂体积 质量 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.4231 mL 12.1156 mL 24.2313 mL 60.5782 mL
5 mM 0.4846 mL 2.4231 mL 4.8463 mL 12.1156 mL
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

β-Sitostenone1058-61-3Δ4-Sitosterol-3-one β-Rosasterol oxideTyrosinaseEndogenous MetaboliteAnti-tumoranti-melanogenicInhibitorinhibitorinhibit

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目录号：
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