184B5
|
GI50 |
|
Cytotoxicity against human 184B5 cells at 20 uM chloroquine by SRB assay
Cytotoxicity against human 184B5 cells at 20 uM chloroquine by SRB assay
|
[PMID: 18691894]
|
184B5
|
GI50 |
|
Cytotoxicity against human 184B5 cells at 10 uM chloroquine by SRB assay
Cytotoxicity against human 184B5 cells at 10 uM chloroquine by SRB assay
|
[PMID: 18691894]
|
184B5
|
GI50 |
|
Cytotoxicity against human 184B5 cells by SRB assay
Cytotoxicity against human 184B5 cells by SRB assay
|
[PMID: 18691894]
|
AA5
|
IC50 |
|
Antiviral activity against of Human immunodeficiency virus 1 3B infected in AA5 cells infected with 3.13 uL of virus stock assessed as inhibition of viral Reverse transcriptase by [3H]TTP incorporation assay
Antiviral activity against of Human immunodeficiency virus 1 3B infected in AA5 cells infected with 3.13 uL of virus stock assessed as inhibition of viral Reverse transcriptase by [3H]TTP incorporation assay
|
[PMID: 20086149]
|
AA5
|
IC50 |
|
Antiviral activity against of Human immunodeficiency virus 1 3B infected in AA5 cells infected with 1.56 uL of virus stock assessed as inhibition of viral Reverse transcriptase by [3H]TTP incorporation assay
Antiviral activity against of Human immunodeficiency virus 1 3B infected in AA5 cells infected with 1.56 uL of virus stock assessed as inhibition of viral Reverse transcriptase by [3H]TTP incorporation assay
|
[PMID: 20086149]
|
AA5
|
IC50 |
|
Antiviral activity against of Human immunodeficiency virus 1 3B infected in AA5 cells infected with 0.78 uL of virus stock assessed as inhibition of viral Reverse transcriptase by [3H]TTP incorporation assay
Antiviral activity against of Human immunodeficiency virus 1 3B infected in AA5 cells infected with 0.78 uL of virus stock assessed as inhibition of viral Reverse transcriptase by [3H]TTP incorporation assay
|
[PMID: 20086149]
|
AA5
|
IC50 |
|
Antiviral activity against Human immunodeficiency virus 1 3B infected in AA5 cells infected with 3.13 uL of virus stock assessed as expression of p24 antigen after 6 days postinfection by ELISA
Antiviral activity against Human immunodeficiency virus 1 3B infected in AA5 cells infected with 3.13 uL of virus stock assessed as expression of p24 antigen after 6 days postinfection by ELISA
|
[PMID: 20086149]
|
AA5
|
IC50 |
|
Antiviral activity against Human immunodeficiency virus 1 3B infected in AA5 cells infected with 1.56 uL of virus stock assessed as expression of p24 antigen after 6 days postinfection by ELISA
Antiviral activity against Human immunodeficiency virus 1 3B infected in AA5 cells infected with 1.56 uL of virus stock assessed as expression of p24 antigen after 6 days postinfection by ELISA
|
[PMID: 20086149]
|
AA5
|
IC50 |
|
Antiviral activity against Human immunodeficiency virus 1 3B infected in AA5 cells infected with 0.78 uL of virus stock assessed as expression of p24 antigen after 6 days postinfection by ELISA
Antiviral activity against Human immunodeficiency virus 1 3B infected in AA5 cells infected with 0.78 uL of virus stock assessed as expression of p24 antigen after 6 days postinfection by ELISA
|
[PMID: 20086149]
|
AA5
|
IC50 |
|
Cytotoxicity against human AA5 cells by MTS assay
Cytotoxicity against human AA5 cells by MTS assay
|
[PMID: 20086149]
|
ACH-2 cell line
|
CC50 |
|
Cytotoxicity against human ACH2 cells infected with latent Human immunodeficiency virus 1 by MTS assay
Cytotoxicity against human ACH2 cells infected with latent Human immunodeficiency virus 1 by MTS assay
|
[PMID: 20086149]
|
ACH-2 cell line
|
CC50 |
|
Cytotoxicity against human ACH2 cells infected with latent Human immunodeficiency virus 1 by MTS assay in presence of tumor necrosis factor alpha
Cytotoxicity against human ACH2 cells infected with latent Human immunodeficiency virus 1 by MTS assay in presence of tumor necrosis factor alpha
|
[PMID: 20086149]
|
ACH-2 cell line
|
IC50 |
|
Antiviral activity against 5 x 10'3 cells/well Human immunodeficiency virus 1 infected in human ACH2 cells assessed as inhibition of viral Reverse transcriptase after 3 days by [3H]TTP incorporation assay in presence of 5 ng/ml tumor necrosis factor alpha
Antiviral activity against 5 x 10'3 cells/well Human immunodeficiency virus 1 infected in human ACH2 cells assessed as inhibition of viral Reverse transcriptase after 3 days by [3H]TTP incorporation assay in presence of 5 ng/ml tumor necrosis factor alpha
|
[PMID: 20086149]
|
BSC-1
|
IC50 |
23 μM
Compound: Triciribine(TCN)
|
Antiviral activity was tested using an enzyme-linked immunosorbent assay (ELISA) to detect HSV-1 (herpes simplex virus type 1) using BSC-1 cells
Antiviral activity was tested using an enzyme-linked immunosorbent assay (ELISA) to detect HSV-1 (herpes simplex virus type 1) using BSC-1 cells
|
[PMID: 10882371]
|
BSC-1
|
IC50 |
|
Antiviral activity against HSV-1 was determined using BSC-1 cells by an enzyme-linked immunosorbent assay (ELISA)
Antiviral activity against HSV-1 was determined using BSC-1 cells by an enzyme-linked immunosorbent assay (ELISA)
|
[PMID: 10882373]
|
CEM-SS
|
IC50 |
|
Antiviral activity against Human immunodeficiency virus 1 3B infected in human CEM-SS cells infected with 0.78 uL of virus stock assessed as expression of p24 antigen after 6 days postinfection by ELISA
Antiviral activity against Human immunodeficiency virus 1 3B infected in human CEM-SS cells infected with 0.78 uL of virus stock assessed as expression of p24 antigen after 6 days postinfection by ELISA
|
[PMID: 20086149]
|
CEM-SS
|
IC50 |
|
Antiviral activity against Human immunodeficiency virus 1 harboring plasmid TAK-1 infected in CEM-SS cells assessed as inhibition of viral Reverse transcriptase by [3H]TTP incorporation assay
Antiviral activity against Human immunodeficiency virus 1 harboring plasmid TAK-1 infected in CEM-SS cells assessed as inhibition of viral Reverse transcriptase by [3H]TTP incorporation assay
|
[PMID: 20086149]
|
CEM-SS
|
IC50 |
|
Cytotoxicity against human CEM-SS cells by MTS assay
Cytotoxicity against human CEM-SS cells by MTS assay
|
[PMID: 20086149]
|
CEM-SS
|
IC50 |
|
Antiviral activity against Human immunodeficiency virus 1 A12 harboring Tyr127His, Asp174Asn and Arg178Lys mutations in nef protein infecting in CEM-SS cells assessed as inhibition of viral Reverse transcriptase by [3H]TTP incorporation assay
Antiviral activity against Human immunodeficiency virus 1 A12 harboring Tyr127His, Asp174Asn and Arg178Lys mutations in nef protein infecting in CEM-SS cells assessed as inhibition of viral Reverse transcriptase by [3H]TTP incorporation assay
|
[PMID: 20086149]
|
CEM-SS
|
IC50 |
|
Antiviral activity against Human immunodeficiency virus 1 H10 harboring Tyr127His, Gly140Glu, Glu149Lys, Asp174Asn and Arg178Lys mutations in nef protein infecting in CEM-SS cells assessed as inhibition of viral Reverse transcriptase by [3H]TTP incorporat
Antiviral activity against Human immunodeficiency virus 1 H10 harboring Tyr127His, Gly140Glu, Glu149Lys, Asp174Asn and Arg178Lys mutations in nef protein infecting in CEM-SS cells assessed as inhibition of viral Reverse transcriptase by [3H]TTP incorporat
|
[PMID: 20086149]
|
CEM-SS
|
IC50 |
|
Antiviral activity against Human immunodeficiency virus 1 3B expressing nef protein infecting in CEM-SS cells assessed as inhibition of viral Reverse transcriptase by [3H]TTP incorporation assay
Antiviral activity against Human immunodeficiency virus 1 3B expressing nef protein infecting in CEM-SS cells assessed as inhibition of viral Reverse transcriptase by [3H]TTP incorporation assay
|
[PMID: 20086149]
|
CEM-SS
|
IC50 |
|
Antiviral activity against Human immunodeficiency virus 1 3B infected in human CEM-SS cells infected with 0.78 uL of virus stock assessed as inhibition of viral Reverse transcriptase by [3H]TTP incorporation assay
Antiviral activity against Human immunodeficiency virus 1 3B infected in human CEM-SS cells infected with 0.78 uL of virus stock assessed as inhibition of viral Reverse transcriptase by [3H]TTP incorporation assay
|
[PMID: 20086149]
|
CEM-SS
|
IC50 |
|
Antiviral activity against Human immunodeficiency virus 1 SK1 infected in human CEM-SS cells assessed as inhibition of viral Reverse transcriptase by [3H]TTP incorporation assay
Antiviral activity against Human immunodeficiency virus 1 SK1 infected in human CEM-SS cells assessed as inhibition of viral Reverse transcriptase by [3H]TTP incorporation assay
|
[PMID: 20086149]
|
CEM-SS
|
IC50 |
|
Antiviral activity against Human immunodeficiency virus 1 3B infected in human CEM-SS cells infected with 1.56 uL of virus stock assessed as expression of p24 antigen after 6 days postinfection by ELISA
Antiviral activity against Human immunodeficiency virus 1 3B infected in human CEM-SS cells infected with 1.56 uL of virus stock assessed as expression of p24 antigen after 6 days postinfection by ELISA
|
[PMID: 20086149]
|
CEM-SS
|
IC50 |
|
Antiviral activity against Human immunodeficiency virus 1 harboring plasmid NL4-3 infected in CEM-SS cells assessed as inhibition of viral Reverse transcriptase by [3H]TTP incorporation assay
Antiviral activity against Human immunodeficiency virus 1 harboring plasmid NL4-3 infected in CEM-SS cells assessed as inhibition of viral Reverse transcriptase by [3H]TTP incorporation assay
|
[PMID: 20086149]
|
CEM-SS
|
IC50 |
|
Antiviral activity against Human immunodeficiency virus 1 3B infected in human CEM-SS cells infected with 3.13 uL of virus stock assessed as expression of p24 antigen after 6 days postinfection by ELISA
Antiviral activity against Human immunodeficiency virus 1 3B infected in human CEM-SS cells infected with 3.13 uL of virus stock assessed as expression of p24 antigen after 6 days postinfection by ELISA
|
[PMID: 20086149]
|
CEM-SS
|
IC50 |
|
Antiviral activity against Human immunodeficiency virus 1 3B infected in human CEM-SS cells infected with 1.56 uL of virus stock assessed as inhibition of viral Reverse transcriptase by [3H]TTP incorporation assay
Antiviral activity against Human immunodeficiency virus 1 3B infected in human CEM-SS cells infected with 1.56 uL of virus stock assessed as inhibition of viral Reverse transcriptase by [3H]TTP incorporation assay
|
[PMID: 20086149]
|
CEM-SS
|
IC50 |
|
Antiviral activity against Human immunodeficiency virus 1 3B infected in human CEM-SS cells infected with 3.13 uL of virus stock assessed as inhibition of viral Reverse transcriptase by [3H]TTP incorporation assay
Antiviral activity against Human immunodeficiency virus 1 3B infected in human CEM-SS cells infected with 3.13 uL of virus stock assessed as inhibition of viral Reverse transcriptase by [3H]TTP incorporation assay
|
[PMID: 20086149]
|
CEM-SS
|
IC50 |
|
Antiviral activity against Human immunodeficiency virus 1 D1 harboring Tyr127His mutation in nef protein infecting in CEM-SS cells assessed as inhibition of viral Reverse transcriptase by [3H]TTP incorporation assay
Antiviral activity against Human immunodeficiency virus 1 D1 harboring Tyr127His mutation in nef protein infecting in CEM-SS cells assessed as inhibition of viral Reverse transcriptase by [3H]TTP incorporation assay
|
[PMID: 20086149]
|
CEM-SS
|
IC50 |
|
Antiviral activity against Human immunodeficiency virus 1 A7 harboring Tyr127His mutation in nef protein infecting in CEM-SS cells assessed as inhibition of viral Reverse transcriptase by [3H]TTP incorporation assay
Antiviral activity against Human immunodeficiency virus 1 A7 harboring Tyr127His mutation in nef protein infecting in CEM-SS cells assessed as inhibition of viral Reverse transcriptase by [3H]TTP incorporation assay
|
[PMID: 20086149]
|
CEM-SS
|
IC50 |
|
Antiviral activity against Human immunodeficiency virus 2 ROD infected in human CEM-SS cells assessed as inhibition of viral Reverse transcriptase by [3H]TTP incorporation assay
Antiviral activity against Human immunodeficiency virus 2 ROD infected in human CEM-SS cells assessed as inhibition of viral Reverse transcriptase by [3H]TTP incorporation assay
|
[PMID: 20086149]
|
CEM-SS
|
CC50 |
|
Cytotoxicity against human CEM-SS cells infected with Human immunodeficiency virus 2 ROD by MTS assay
Cytotoxicity against human CEM-SS cells infected with Human immunodeficiency virus 2 ROD by MTS assay
|
[PMID: 20086149]
|
CEM-SS
|
CC50 |
|
Cytotoxicity against human CEM-SS cells by MTS assay
Cytotoxicity against human CEM-SS cells by MTS assay
|
[PMID: 20086149]
|
CEM-SS
|
CC50 |
|
Cytotoxicity against human CEM-SS cells infected with Human immunodeficiency virus 1 SK1 by MTS assay
Cytotoxicity against human CEM-SS cells infected with Human immunodeficiency virus 1 SK1 by MTS assay
|
[PMID: 20086149]
|
H9
|
IC50 |
|
Antiviral activity against Human immunodeficiency virus 1 3B infected in human H9 cells infected with 12.5 uL of virus stock assessed as expression of p24 antigen after 6 days postinfection by ELISA
Antiviral activity against Human immunodeficiency virus 1 3B infected in human H9 cells infected with 12.5 uL of virus stock assessed as expression of p24 antigen after 6 days postinfection by ELISA
|
[PMID: 20086149]
|
H9
|
IC50 |
|
Antiviral activity against Human immunodeficiency virus 1 3B infected in human H9 cells infected with 6.25 uL of virus stock assessed as expression of p24 antigen after 6 days postinfection by ELISA
Antiviral activity against Human immunodeficiency virus 1 3B infected in human H9 cells infected with 6.25 uL of virus stock assessed as expression of p24 antigen after 6 days postinfection by ELISA
|
[PMID: 20086149]
|
H9
|
IC50 |
|
Antiviral activity against Human immunodeficiency virus 1 3B infected in human H9 cells infected with 25 uL of virus stock assessed as inhibition of viral Reverse transcriptase by [3H]TTP incorporation assay
Antiviral activity against Human immunodeficiency virus 1 3B infected in human H9 cells infected with 25 uL of virus stock assessed as inhibition of viral Reverse transcriptase by [3H]TTP incorporation assay
|
[PMID: 20086149]
|
H9
|
IC50 |
|
Antiviral activity against Human immunodeficiency virus 1 3B infected in human H9 cells infected with 12.5 uL of virus stock assessed as inhibition of viral Reverse transcriptase by [3H]TTP incorporation assay
Antiviral activity against Human immunodeficiency virus 1 3B infected in human H9 cells infected with 12.5 uL of virus stock assessed as inhibition of viral Reverse transcriptase by [3H]TTP incorporation assay
|
[PMID: 20086149]
|
H9
|
IC50 |
|
Antiviral activity against Human immunodeficiency virus 1 3B infected in human H9 cells infected with 6.25 uL of virus stock assessed as inhibition of viral Reverse transcriptase by [3H]TTP incorporation assay
Antiviral activity against Human immunodeficiency virus 1 3B infected in human H9 cells infected with 6.25 uL of virus stock assessed as inhibition of viral Reverse transcriptase by [3H]TTP incorporation assay
|
[PMID: 20086149]
|
H9
|
IC50 |
|
Antiviral activity against Human immunodeficiency virus 1 3B infected in human H9 cells infected with 50 uL of virus stock assessed as expression of p24 antigen after 6 days postinfection by ELISA
Antiviral activity against Human immunodeficiency virus 1 3B infected in human H9 cells infected with 50 uL of virus stock assessed as expression of p24 antigen after 6 days postinfection by ELISA
|
[PMID: 20086149]
|
H9
|
IC50 |
|
Antiviral activity against Human immunodeficiency virus 1 3B infected in human H9 cells infected with 25 uL of virus stock assessed as expression of p24 antigen after 6 days postinfection by ELISA
Antiviral activity against Human immunodeficiency virus 1 3B infected in human H9 cells infected with 25 uL of virus stock assessed as expression of p24 antigen after 6 days postinfection by ELISA
|
[PMID: 20086149]
|
H9
|
IC50 |
|
Antiviral activity against Human immunodeficiency virus 1 SK1 infected in human H9 cells assessed as inhibition of viral Reverse transcriptase by [3H]TTP incorporation assay
Antiviral activity against Human immunodeficiency virus 1 SK1 infected in human H9 cells assessed as inhibition of viral Reverse transcriptase by [3H]TTP incorporation assay
|
[PMID: 20086149]
|
H9
|
IC50 |
|
Antiviral activity against Human immunodeficiency virus 1 3B infected in human H9 cells infected with 50 uL of virus stock assessed as inhibition of viral Reverse transcriptase by [3H]TTP incorporation assay
Antiviral activity against Human immunodeficiency virus 1 3B infected in human H9 cells infected with 50 uL of virus stock assessed as inhibition of viral Reverse transcriptase by [3H]TTP incorporation assay
|
[PMID: 20086149]
|
H9
|
IC50 |
|
Cytotoxicity against human H9 cells by MTS assay
Cytotoxicity against human H9 cells by MTS assay
|
[PMID: 20086149]
|
H9
|
CC50 |
|
Cytotoxicity against human H9 cells by MTS assay
Cytotoxicity against human H9 cells by MTS assay
|
[PMID: 20086149]
|
HFF
|
IC50 |
|
Visual cytotoxicity was determined in uninfected HFF cells using plaque assay
Visual cytotoxicity was determined in uninfected HFF cells using plaque assay
|
[PMID: 15916436]
|
HFF
|
IC50 |
2.5 μM
Compound: Triciribine(TCN)
|
HCMV plaque assay was performed using HFF cells and effect was calculated as a percentage of reduction in number of plaques
HCMV plaque assay was performed using HFF cells and effect was calculated as a percentage of reduction in number of plaques
|
[PMID: 10882371]
|
HFF
|
IC50 |
|
Antiviral activity against HCMV was determined by plaque reduction assay using HFF cells
Antiviral activity against HCMV was determined by plaque reduction assay using HFF cells
|
[PMID: 10882373]
|
Huh-7
|
CC50 |
|
Cytotoxicity using HCV replicon assay
Cytotoxicity using HCV replicon assay
|
[PMID: 15177464]
|
MCF7
|
GI50 |
|
Cytotoxicity against human MCF7 cells in presence of 20 uM chloroquine by SRB assay
Cytotoxicity against human MCF7 cells in presence of 20 uM chloroquine by SRB assay
|
[PMID: 18691894]
|
MCF7
|
GI50 |
|
Cytotoxicity against human MCF7 cells in presence of 10 uM chloroquine by SRB assay
Cytotoxicity against human MCF7 cells in presence of 10 uM chloroquine by SRB assay
|
[PMID: 18691894]
|
MCF7
|
GI50 |
|
Cytotoxicity against human MCF7 cells by SRB assay
Cytotoxicity against human MCF7 cells by SRB assay
|
[PMID: 18691894]
|
MDA-MB-231
|
GI50 |
|
Cytotoxicity against human MDA-MB-231 cells in presence of 20 uM chloroquine by SRB assay
Cytotoxicity against human MDA-MB-231 cells in presence of 20 uM chloroquine by SRB assay
|
[PMID: 18691894]
|
MDA-MB-231
|
GI50 |
|
Cytotoxicity against human MDA-MB-231 cells in presence of 10 uM chloroquine by SRB assay
Cytotoxicity against human MDA-MB-231 cells in presence of 10 uM chloroquine by SRB assay
|
[PMID: 18691894]
|
MDA-MB-231
|
GI50 |
|
Cytotoxicity against human MDA-MB-231 cells by SRB assay
Cytotoxicity against human MDA-MB-231 cells by SRB assay
|
[PMID: 18691894]
|
MDA-MB-468
|
GI50 |
|
Cytotoxicity against human MDA-MB-468 cells in presence of 20 uM chloroquine by SRB assay
Cytotoxicity against human MDA-MB-468 cells in presence of 20 uM chloroquine by SRB assay
|
[PMID: 18691894]
|
MDA-MB-468
|
GI50 |
|
Cytotoxicity against human MDA-MB-468 cells in presence of 10 uM chloroquine by SRB assay
Cytotoxicity against human MDA-MB-468 cells in presence of 10 uM chloroquine by SRB assay
|
[PMID: 18691894]
|
MDA-MB-468
|
GI50 |
|
Cytotoxicity against human MDA-MB-468 cells by SRB assay
Cytotoxicity against human MDA-MB-468 cells by SRB assay
|
[PMID: 18691894]
|
U1
|
IC50 |
|
Antiviral activity against Human immunodeficiency virus 1 infected in human U1 cells assessed as inhibition of viral Reverse transcriptase by [3H]TTP incorporation assay
Antiviral activity against Human immunodeficiency virus 1 infected in human U1 cells assessed as inhibition of viral Reverse transcriptase by [3H]TTP incorporation assay
|
[PMID: 20086149]
|
U1
|
CC50 |
|
Cytotoxicity against human U1 cells infected with latent Human immunodeficiency virus 1 by MTS assay
Cytotoxicity against human U1 cells infected with latent Human immunodeficiency virus 1 by MTS assay
|
[PMID: 20086149]
|
U1
|
CC50 |
|
Cytotoxicity against human U1 cells infected with latent Human immunodeficiency virus 1 by MTS assay in presence of tumor necrosis factor alpha
Cytotoxicity against human U1 cells infected with latent Human immunodeficiency virus 1 by MTS assay in presence of tumor necrosis factor alpha
|
[PMID: 20086149]
|