2. Gene
  3. NUTF2 - nuclear transport factor 2 Gene

NUTF2 - nuclear transport factor 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

中文名称：核运输因子 2

种属: Homo sapiens

同用名: NTF2; PP15; NTF-2

基因 ID: 10204 | 基因类型: protein coding

关于 NUTF2

Cytogenetic location: 16q22.1 Genomic coordinates (GRCh38): 16:67,846,933-67,872,567 (from NCBI)

This gene has 14 transcripts (splice variants), 235 orthologues and 2 paralogues. Ubiquitous expression in placenta (RPKM 14.8), testis (RPKM 14.7) and 25 other tissues.

功能概要

该基因编码促进蛋白质转运至细胞核的胞质因子。编码的蛋白质是小 Ras 样 GTP 酶 Ran 的核输入所必需的，它参与许多细胞过程。该蛋白质还与核孔复合糖蛋白 p62 相互作用。[RefSeq 提供，2016 年 4 月]

This gene encodes a cytosolic factor that facilitates protein transport into the nucleus. The encoded protein is required for nuclear import of the small Ras-like GTPase, Ran which is involved in numerous cellular processes. This protein also interacts with the nuclear pore complex glycoprotein p62. [provided by RefSeq, Apr 2016]

NUTF2 基因产物(5)

mRNA Protein Name
NM_001322038.2 NP_001308967.1 nuclear transport factor 2
NM_001322039.2 NP_001308968.1 nuclear transport factor 2
NM_001322040.2 NP_001308969.1 nuclear transport factor 2
NM_001322041.2 NP_001308970.1 nuclear transport factor 2
NM_005796.3 NP_005787.1 nuclear transport factor 2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables identical protein binding IPI
IPI: 通过物理相互作用推断
19098896 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
7744965 GOA
enables small GTPase binding IDA
IDA: 通过直接分析推断
10679025 GOA
enables small GTPase binding IPI
IPI: 通过物理相互作用推断
18266911 GOA
enables structural constituent of nuclear pore IDA
IDA: 通过直接分析推断
7744965 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in protein export from nucleus IDA
IDA: 通过直接分析推断
16449645 GOA
involved in protein import into nucleus IDA
IDA: 通过直接分析推断
7744965 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytosol IDA
IDA: 通过直接分析推断
7744965 GOA
located in nucleoplasm IDA
IDA: 通过直接分析推断
10679025 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

NUTF2 蛋白结构

NTF2

NTF2: Nuclear transport factor 2 (NTF2) domain (11 - 121)

  • 0
  • 100
  • 127 a.a.
蛋白主名 其他名称

nuclear transport factor 2

placental protein 15

NUTF2 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
NUTF2 P61970 BEND7 Homo sapiens Q8N7W2-2
Y2H Prey Pooling
32296183
种属内
NUTF2 P61970 BEND7 Homo sapiens Q8N7W2-2
Y2H Array
32296183
种属内
NUTF2 P61970 BEND7 Homo sapiens Q8N7W2-2
Validated Y2H
32296183
种属内
NUTF2 P61970 PAX4 Homo sapiens Q3KNR5
Y2H Prey Pooling
32296183
种属内
NUTF2 P61970 PAX4 Homo sapiens Q3KNR5
Validated Y2H
32296183
种属内
NUTF2 P61970 PAX4 Homo sapiens Q3KNR5
Y2H Array
32296183
种属内
NUTF2 P61970 PBX4 Homo sapiens Q9BYU1
Y2H Prey Pooling
32296183
种属内
NUTF2 P61970 PBX4 Homo sapiens Q9BYU1
Validated Y2H
32296183
种属内
NUTF2 P61970 PBX4 Homo sapiens Q9BYU1
Y2H Array
32296183
种属内
NUTF2 P61970 NRIP3 Homo sapiens Q9NQ35
Y2H Prey Pooling
32296183
种属内
NUTF2 P61970 NRIP3 Homo sapiens Q9NQ35
Validated Y2H
32296183
种属内
NUTF2 P61970 NRIP3 Homo sapiens Q9NQ35
Y2H Array
32296183
种属内
NUTF2 P61970 CKMT1A Homo sapiens P12532
Y2H Array
32296183
种属内
NUTF2 P61970 CKMT1A Homo sapiens P12532
Y2H Prey Pooling
32296183
种属内
NUTF2 P61970 CLPP Homo sapiens Q16740
Y2H Prey Pooling
32296183
种属内
NUTF2 P61970 CLPP Homo sapiens Q16740
Validated Y2H
32296183
种属内
NUTF2 P61970 CLPP Homo sapiens Q16740
Y2H Array
32296183
种属内
NUTF2 P61970 BRWD1 Homo sapiens Q9NSI6-4
Validated Y2H
32296183
种属内
NUTF2 P61970 BRWD1 Homo sapiens Q9NSI6-4
Y2H Array
32296183
种属内
NUTF2 P61970 BRWD1 Homo sapiens Q9NSI6-4
Y2H Prey Pooling
32296183
种属内
NUTF2 P61970 TLE5 Homo sapiens Q08117-2
Validated Y2H
32296183
种属内
NUTF2 P61970 TLE5 Homo sapiens Q08117-2
Y2H Prey Pooling
32296183
种属内
NUTF2 P61970 TLE5 Homo sapiens Q08117-2
Y2H Array
32296183
种属内
NUTF2 P61970 LCE5A Homo sapiens Q5TCM9
Validated Y2H
32296183
种属内
NUTF2 P61970 LCE5A Homo sapiens Q5TCM9
Y2H Array
32296183
种属内
NUTF2 P61970 LCE5A Homo sapiens Q5TCM9
Y2H Prey Pooling
32296183
种属内
NUTF2 P61970 KRTAP9-8 Homo sapiens Q9BYQ0
Y2H Array
32296183
种属内
NUTF2 P61970 KRTAP9-8 Homo sapiens Q9BYQ0
Y2H Prey Pooling
32296183
种属内
NUTF2 P61970 KRTAP9-8 Homo sapiens Q9BYQ0
Validated Y2H
32296183
种属内
NUTF2 P61970 SPATC1L Homo sapiens Q9H0A9-2
Validated Y2H
32296183
种属内
NUTF2 P61970 SPATC1L Homo sapiens Q9H0A9-2
Y2H Array
32296183
种属内
NUTF2 P61970 SPATC1L Homo sapiens Q9H0A9-2
Y2H Prey Pooling
32296183
种属内
NUTF2 P61970 CAMK2G Homo sapiens Q13555-5
Y2H Array
32296183
种属内
NUTF2 P61970 CAMK2G Homo sapiens Q13555-5
Validated Y2H
32296183
种属内
NUTF2 P61970 CAMK2G Homo sapiens Q13555-5
Y2H Prey Pooling
32296183
种属内
NUTF2 P61970 YAF2 Homo sapiens Q8IY57-5
Y2H Prey Pooling
32296183
种属内
NUTF2 P61970 YAF2 Homo sapiens Q8IY57-5
Y2H Array
32296183
种属内
NUTF2 P61970 YAF2 Homo sapiens Q8IY57-5
Validated Y2H
32296183
种属内
NUTF2 P61970 CHMP4A Homo sapiens Q9BY43-2
Validated Y2H
32296183
种属内
NUTF2 P61970 CHMP4A Homo sapiens Q9BY43-2
Y2H Prey Pooling
32296183
种属内
NUTF2 P61970 CHMP4A Homo sapiens Q9BY43-2
Y2H Array
32296183
种属内
NUTF2 P61970 LCE1C Homo sapiens Q5T751
Validated Y2H
32296183
种属内
NUTF2 P61970 LCE1C Homo sapiens Q5T751
Y2H Array
32296183
种属内
NUTF2 P61970 LCE1C Homo sapiens Q5T751
Y2H Prey Pooling
32296183
种属内
NUTF2 P61970 CCDC150 Homo sapiens Q8NCX0-3
Validated Y2H
32296183
种属内
NUTF2 P61970 CCDC150 Homo sapiens Q8NCX0-3
Y2H Array
32296183
种属内
NUTF2 P61970 CCDC150 Homo sapiens Q8NCX0-3
Y2H Prey Pooling
32296183
种属内
NUTF2 P61970 TEX35 Homo sapiens Q5T0J7-2
Validated Y2H
32296183
种属内
NUTF2 P61970 TEX35 Homo sapiens Q5T0J7-2
Y2H Array
32296183
种属内
NUTF2 P61970 TEX35 Homo sapiens Q5T0J7-2
Y2H Prey Pooling
32296183
种属内
NUTF2 P61970 THAP3 Homo sapiens Q8WTV1
Y2H Prey Pooling
32296183
种属内
NUTF2 P61970 THAP3 Homo sapiens Q8WTV1
Y2H Array
32296183
种属内
NUTF2 P61970 THAP3 Homo sapiens Q8WTV1
Validated Y2H
32296183
种属内
NUTF2 P61970 UBAP2 Homo sapiens Q5T6F2
Validated Y2H
32296183
种属内
NUTF2 P61970 UBAP2 Homo sapiens Q5T6F2
Y2H Prey Pooling
32296183
种属内
NUTF2 P61970 UBAP2 Homo sapiens Q5T6F2
Y2H Array
32296183
种属内
NUTF2 P61970 ZMAT2 Homo sapiens Q96NC0
Y2H Array
32296183
种属内
NUTF2 P61970 ZMAT2 Homo sapiens Q96NC0
Validated Y2H
32296183
种属内
NUTF2 P61970 ZMAT2 Homo sapiens Q96NC0
Y2H Prey Pooling
32296183
种属内
NUTF2 P61970 MRNIP Homo sapiens Q6NTE8
Validated Y2H
32296183
种属内
NUTF2 P61970 MRNIP Homo sapiens Q6NTE8
Y2H Array
32296183
种属内
NUTF2 P61970 MRNIP Homo sapiens Q6NTE8
Y2H Prey Pooling
32296183
种属内
NUTF2 P61970 PHF11 Homo sapiens Q9UIL8
Y2H Prey Pooling
32296183
种属内
NUTF2 P61970 PHF11 Homo sapiens Q9UIL8
Validated Y2H
32296183
种属内
NUTF2 P61970 PHF11 Homo sapiens Q9UIL8
Y2H Array
32296183
种属内
NUTF2 P61970 RAN Homo sapiens P62826
Comig Non-Denat Gel
19098896
种属内
NUTF2 P61970 RAN Homo sapiens P62826
Anti Tag CoIP
35271311
种属内
NUTF2 P61970 NUP62 Homo sapiens P37198
Y2H Prey Pooling
32296183
种属内
NUTF2 P61970 NUP62 Homo sapiens P37198
Y2H Array
31515488
种属内
NUTF2 P61970 NUP62 Homo sapiens P37198
Validated Y2H
25416956
种属内
NUTF2 P61970 NUP62 Homo sapiens P37198
Y2H Array
32296183
种属内
NUTF2 P61970 NUP62 Homo sapiens P37198
Y2H Array
25416956
种属内
NUTF2 P61970 SPRY4 Homo sapiens Q9C004
Validated Y2H
32296183
种属内
NUTF2 P61970 SPRY4 Homo sapiens Q9C004
Y2H Prey Pooling
32296183
种属内
NUTF2 P61970 SPRY4 Homo sapiens Q9C004
Y2H Array
32296183
种属内
NUTF2 P61970 PCNA Homo sapiens P12004
Y2H Prey Pooling
32296183
种属内
NUTF2 P61970 PCNA Homo sapiens P12004
Y2H Array
32296183
种属内
NUTF2 P61970 PFKP Homo sapiens Q01813
Validated Y2H
32296183
种属内
NUTF2 P61970 PFKP Homo sapiens Q01813
Y2H Array
32296183
种属内
NUTF2 P61970 PFKP Homo sapiens Q01813
Y2H Prey Pooling
32296183
种属内
NUTF2 P61970 MYOZ3 Homo sapiens Q8TDC0
Y2H Prey Pooling
32296183
种属内
NUTF2 P61970 MYOZ3 Homo sapiens Q8TDC0
Validated Y2H
32296183
种属内
NUTF2 P61970 MYOZ3 Homo sapiens Q8TDC0
Y2H Array
32296183
种属内
NUTF2 P61970 NUTF2 Homo sapiens P61970
Comig Non-Denat Gel
19098896
种属内
NUTF2 P61970 NUTF2 Homo sapiens P61970
Y2H Array
25416956
种属内
NUTF2 P61970 NUTF2 Homo sapiens P61970
GMS
19098896
种属内
NUTF2 P61970 PPP1R16A Homo sapiens Q96I34
Validated Y2H
32296183
种属内
NUTF2 P61970 PPP1R16A Homo sapiens Q96I34
Y2H Prey Pooling
32296183
种属内
NUTF2 P61970 PPP1R16A Homo sapiens Q96I34
Y2H Array
32296183
种属内
NUTF2 P61970 CCDC106 Homo sapiens Q9BWC9
Y2H Array
32296183
种属内
NUTF2 P61970 CCDC106 Homo sapiens Q9BWC9
Validated Y2H
32296183
种属内
NUTF2 P61970 CCDC106 Homo sapiens Q9BWC9
Y2H Prey Pooling
32296183
种属内
NUTF2 P61970 HMG20B Homo sapiens Q9P0W2
Y2H Array
32296183
种属内
NUTF2 P61970 HMG20B Homo sapiens Q9P0W2
Y2H Prey Pooling
32296183
种属内
NUTF2 P61970 HMG20B Homo sapiens Q9P0W2
Validated Y2H
32296183
种属内
NUTF2 P61970 LENG1 Homo sapiens Q96BZ8
Y2H Prey Pooling
32296183
种属内
NUTF2 P61970 LENG1 Homo sapiens Q96BZ8
Validated Y2H
32296183
种属内
NUTF2 P61970 LENG1 Homo sapiens Q96BZ8
Y2H Array
32296183
种属内
NUTF2 P61970 HMG20A Homo sapiens Q9NP66
Y2H Prey Pooling
32296183
种属内
NUTF2 P61970 HMG20A Homo sapiens Q9NP66
Validated Y2H
32296183
种属内
NUTF2 P61970 HMG20A Homo sapiens Q9NP66
Y2H Array
32296183
种属内
NUTF2 P61970 NUP54 Homo sapiens Q7Z3B4
Validated Y2H
32296183
种属内
NUTF2 P61970 NUP54 Homo sapiens Q7Z3B4
Y2H Array
32296183
种属内
NUTF2 P61970 NUP54 Homo sapiens Q7Z3B4
Y2H Prey Pooling
32296183
种属内
NUTF2 P61970 NME1 Homo sapiens P15531
Y2H Prey Pooling
32296183
种属内
NUTF2 P61970 NME1 Homo sapiens P15531
Y2H Array
32296183
种属内
NUTF2 P61970 FAM50B Homo sapiens Q9Y247
Validated Y2H
32296183
种属内
NUTF2 P61970 FAM50B Homo sapiens Q9Y247
Y2H Array
32296183
种属内
NUTF2 P61970 FAM50B Homo sapiens Q9Y247
Y2H Prey Pooling
32296183
种属内
NUTF2 P61970 CHCHD3 Homo sapiens Q9NX63
Y2H Prey Pooling
32296183
种属内
NUTF2 P61970 CHCHD3 Homo sapiens Q9NX63
Validated Y2H
32296183
种属内
NUTF2 P61970 CHCHD3 Homo sapiens Q9NX63
Y2H Array
32296183
种属内
NUTF2 P61970 NME4 Homo sapiens O00746
Y2H Prey Pooling
32296183
种属内
NUTF2 P61970 NME4 Homo sapiens O00746
Y2H Array
32296183
种属内
NUTF2 P61970 RPRD1B Homo sapiens Q9NQG5
Validated Y2H
32296183
种属内
NUTF2 P61970 RPRD1B Homo sapiens Q9NQG5
Y2H Array
32296183
种属内
NUTF2 P61970 RPRD1B Homo sapiens Q9NQG5
Y2H Prey Pooling
32296183
种属内
NUTF2 P61970 LASP1 Homo sapiens Q14847-2
Y2H Prey Pooling
32296183
种属内
NUTF2 P61970 LASP1 Homo sapiens Q14847-2
Y2H Array
32296183
种属内
NUTF2 P61970 LASP1 Homo sapiens Q14847-2
Validated Y2H
32296183
种属内
NUTF2 P61970 KHDC4 Homo sapiens Q7Z7F0-4
Validated Y2H
32296183
种属内
NUTF2 P61970 KHDC4 Homo sapiens Q7Z7F0-4
Y2H Array
32296183
种属内
NUTF2 P61970 KHDC4 Homo sapiens Q7Z7F0-4
Y2H Prey Pooling
32296183
种属内
NUTF2 P61970 KRT86 Homo sapiens O43790
Y2H Array
32296183
种属内
NUTF2 P61970 KRT86 Homo sapiens O43790
Y2H Prey Pooling
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

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直系同源

种属 基因名 来源 基因 ID
Felis catus NUTF2 VGNC VGNC:97543
Rattus norvegicus NUTF2 RGD RGD:1359213
Mus musculus NUTF2 MGD MGI:1915301
Bos taurus NUTF2 VGNC VGNC:32371
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