1. Gene
  2. MYD88 - MYD88 innate immune signal transduction adaptor Gene

MYD88 - MYD88 innate immune signal transduction adaptor Gene

中文名称:MYD88 先天性免疫信号转导接头

种属: Homo sapiens

同用名: IMD68; MYD88D

基因 ID: 4615 | 基因类型: protein coding

关于 MYD88

Cytogenetic location: 3p22.2 Genomic coordinates (GRCh38): 3:38,138,661-38,143,022 (from NCBI)

This gene has 16 transcripts (splice variants), 200 orthologues and is associated with 79 phenotypes. Ubiquitous expression in appendix (RPKM 32.5), bone marrow (RPKM 32.2) and 25 other tissues.

功能概要

该基因编码一种胞质衔接蛋白,该蛋白在先天性和适应性免疫反应中起着核心作用。这种蛋白质在白细胞介素 1 和 Toll 样受体信号通路中起着重要的信号转导作用。这些途径调节许多促炎基因的激活。编码的蛋白质由一个 N 端死亡结构域和一个 C 端 Toll-interleukin1 受体结构域组成。该基因缺陷的患者对化脓性细菌感染的易感性增加。交替剪接导致多个转录本变体。[RefSeq 提供,2010 年 2 月]

This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and Toll-like Receptor signaling pathways. These pathways regulate that activation of numerous proinflammatory genes. The encoded protein consists of an N-terminal death domain and a C-terminal Toll-interleukin1 receptor domain. Patients with defects in this gene have an increased susceptibility to pyogenic Bacterial infections. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2010]

MYD88 基因产物(10)

mRNA Protein Name
NM_001172567.2 NP_001166038.2 myeloid differentiation primary response protein MyD88 isoform 1
NM_001172568.2 NP_001166039.2 myeloid differentiation primary response protein MyD88 isoform 3
NR_164663.1
NM_001374788.1
NM_001374787.1 NP_001361716.1 myeloid differentiation primary response protein MyD88 isoform 8
NM_001365877.1 NP_001352806.1 myeloid differentiation primary response protein MyD88 isoform 7
NM_002468.5 NP_002459.3 myeloid differentiation primary response protein MyD88 isoform 2
NM_001172569.3 NP_001166040.2 myeloid differentiation primary response protein MyD88 isoform 4
NM_001365876.1 NP_001352805.1 myeloid differentiation primary response protein MyD88 isoform 6
NM_001172566.2 NP_001166037.2 myeloid differentiation primary response protein MyD88 isoform 5
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables TIR domain binding IPI
IPI: 通过物理相互作用推断
19509286 GOA
enables identical protein binding IPI
IPI: 通过物理相互作用推断
11544529 GOA
enables molecular adaptor activity IDA
IDA: 通过直接分析推断
9430229 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
10880445 GOA
enables signaling adaptor activity IDA
IDA: 通过直接分析推断
16751103 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in 3'-UTR-mediated mRNA stabilization IDA
IDA: 通过直接分析推断
15294994 GOA
involved in apoptotic process IMP
IMP: 通过突变表型推断
22155231 GOA
involved in cellular response to mechanical stimulus IEP
IEP: 通过表达模式推断
19593445 GOA
involved in defense response to bacterium IMP
IMP: 通过突变表型推断
20219467 GOA
involved in defense response to virus IDA
IDA: 通过直接分析推断
33718825 GOA
involved in interleukin-1-mediated signaling pathway IDA
IDA: 通过直接分析推断
9430229 GOA
involved in interleukin-33-mediated signaling pathway IDA
IDA: 通过直接分析推断
18802081 GOA
involved in phagocytosis IMP
IMP: 通过突变表型推断
30883606 GOA
involved in positive regulation of NF-kappaB transcription factor activity IMP
IMP: 通过突变表型推断
22155231 GOA
involved in positive regulation of NLRP3 inflammasome complex assembly IMP
IMP: 通过突变表型推断
33718825 GOA
involved in positive regulation of canonical NF-kappaB signal transduction IEP
IEP: 通过表达模式推断
12761501 GOA
involved in positive regulation of cytokine production involved in inflammatory response IMP
IMP: 通过突变表型推断
20219467 GOA
involved in positive regulation of interleukin-1 beta production IDA
IDA: 通过直接分析推断
33718825 GOA
involved in positive regulation of interleukin-8 production IMP
IMP: 通过突变表型推断
20219467 GOA
involved in positive regulation of type I interferon production IMP
IMP: 通过突变表型推断
23633945 GOA
involved in response to interleukin-1 IMP
IMP: 通过突变表型推断
19281832 GOA
involved in toll-like receptor 4 signaling pathway IDA
IDA: 通过直接分析推断
16751103 GOA
involved in toll-like receptor 5 signaling pathway IDA
IDA: 通过直接分析推断
16751103 GOA
involved in toll-like receptor 8 signaling pathway IDA
IDA: 通过直接分析推断
33718825 GOA
involved in toll-like receptor TLR6:TLR2 signaling pathway IDA
IDA: 通过直接分析推断
36964784 GOA
involved in type I interferon-mediated signaling pathway IMP
IMP: 通过突变表型推断
23633945 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
is active in cell surface IDA
IDA: 通过直接分析推断
22851693 GOA
is active in cytoplasm IDA
IDA: 通过直接分析推断
9430229 GOA
located in cytoplasm IDA
IDA: 通过直接分析推断
22155231 GOA
is active in extrinsic component of cytoplasmic side of plasma membrane IDA
IDA: 通过直接分析推断
16751103 GOA
is active in extrinsic component of plasma membrane IDA
IDA: 通过直接分析推断
9430229 GOA
located in nucleus IDA
IDA: 通过直接分析推断
22155231 GOA
is active in plasma membrane IDA
IDA: 通过直接分析推断
16751103 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

MYD88 蛋白结构

Death

Death: Death domain (50 - 115)

TIR

TIR: TIR domain (176 - 304)

  • 0
  • 100
  • 200
  • 309 a.a.
蛋白主名 其他名称

myeloid differentiation primary response protein MyD88

TLR adaptor MYD88

mutant myeloid differentiation primary response 88

myeloid differentiation primary response 88

myeloid differentiation primary response gene (88)

MYD88 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
MYD88 Q99836 IRAK4 Homo sapiens Q69FE3
Y2H Prey Pooling
25416956
种属内
MYD88 Q99836 IRAK4 Homo sapiens Q69FE3
Validated Y2H
25416956
种属内
MYD88 Q99836 IRAK4 Homo sapiens Q69FE3
Y2H Array
25416956
种属内
MYD88 Q99836 SARM1 Homo sapiens Q6SZW1
MAPPIT
17258210
种属内
MYD88 Q99836 STAP2 Homo sapiens Q9UGK3
Anti Tag CoIP
16365431
种属内
MYD88 Q99836 RNF4 Homo sapiens P78317
Y2H Array
32296183
种属内
MYD88 Q99836 RNF4 Homo sapiens P78317
Y2H Prey Pooling
32296183
种属内
MYD88 Q99836 DOCK8 Homo sapiens Q8NF50
Anti Bait CoIP
22581261
种属内
MYD88 Q99836 SPOPL Homo sapiens Q6IQ16
Y2H Prey Pooling
32296183
种属内
MYD88 Q99836 SPOPL Homo sapiens Q6IQ16
Y2H Array
32296183
种属内
MYD88 Q99836 HDAC6 Homo sapiens Q9UBN7
Anti Bait CoIP
29281743
种属内
MYD88 Q99836 HDAC6 Homo sapiens Q9UBN7
Anti Tag CoIP
29281743
种属内
MYD88 Q99836 USP7 Homo sapiens Q93009
Y2H
21988832
种属内
MYD88 Q99836 USP7 Homo sapiens Q93009
Confocal
21988832
种属内
MYD88 Q99836 USP7 Homo sapiens Q93009
Anti Tag CoIP
21988832
种属内
MYD88 Q99836 IRAK1 Homo sapiens P51617
Anti Tag CoIP
10383454
种属内
MYD88 Q99836 MYD88 Homo sapiens Q99836
Y2H
21988832
种属内
MYD88 Q99836 MYD88 Homo sapiens Q99836
MAPPIT
17258210
种属内
MYD88 Q99836 MYD88 Homo sapiens Q99836
SLC
22155231
种属内
MYD88 Q99836 MYD88 Homo sapiens Q99836
Y2H
11544529
种属内
MYD88 Q99836 MYD88 Homo sapiens Q99836
Y2H Array
21988832
种属内
MYD88 Q99836 MYD88 Homo sapiens Q99836
Y2H
21516116
种属内
MYD88 Q99836 IRAK4 Homo sapiens Q9NWZ3
Y2H Array
25502805
种属内
MYD88 Q99836 IRAK4 Homo sapiens Q9NWZ3
Y2H Array
25910212
种属内
MYD88 Q99836 IRAK4 Homo sapiens Q9NWZ3
Y2H Prey Pooling
32296183
种属内
MYD88 Q99836 IRAK4 Homo sapiens Q9NWZ3
Validated Y2H
32296183
种属内
MYD88 Q99836 IRAK4 Homo sapiens Q9NWZ3
Y2H Array
32296183
种属内
MYD88 Q99836 IRAK4 Homo sapiens Q9NWZ3
SLC
25910212
种属内
MYD88 Q99836 IRAK4 Homo sapiens Q9NWZ3
Validated Y2H
25910212
种属内
MYD88 Q99836 IRAK4 Homo sapiens Q9NWZ3
Y2H
12860405
种属内
MYD88 Q99836 IRAK4 Homo sapiens Q9NWZ3
Y2H Array
31515488
种属内
MYD88 Q99836 IRAK4 Homo sapiens Q9NWZ3
Y2H Bait-Prey Pool
25910212
种属内
MYD88 Q99836 FADD Homo sapiens Q13158
CoIP
10880445
种属内
MYD88 Q99836 TNFRSF13B Homo sapiens O14836
Pull Down
20676093
种属内
MYD88 Q99836 TNFRSF13B Homo sapiens O14836
Confocal
20676093
种属内
MYD88 Q99836 TNFRSF13B Homo sapiens O14836
CoIP
20676093
种属内
MYD88 Q99836 TIRAP Homo sapiens P58753
Y2H
11544529
种属内
MYD88 Q99836 TLR4 Homo sapiens O00206
Anti Tag CoIP
15728506
种属内
MYD88 Q99836 TXN Homo sapiens P10599
Anti Tag CoIP
21988832
种属内
MYD88 Q99836 SPOP Homo sapiens O43791
Anti Tag CoIP
33961781
种属内
MYD88 Q99836 SPOP Homo sapiens O43791
Anti Tag CoIP
28514442
种属内
MYD88 Q99836 SPOP Homo sapiens O43791
Y2H Pooling
16189514
种属内
MYD88 Q99836 SPOP Homo sapiens O43791
Y2H Array
21988832
种属内
MYD88 Q99836 SIAH1 Homo sapiens Q8IUQ4
Confocal
21988832
种属内
MYD88 Q99836 SIAH1 Homo sapiens Q8IUQ4
Anti Tag CoIP
21988832
种属内
MYD88 Q99836 TLR2 Homo sapiens O60603
TSA
29990310
种属内
MYD88 Q99836 TLR2 Homo sapiens O60603
SPR
29990310
种属内
MYD88 Q99836 TLR2 Homo sapiens O60603
Confocal
16293622
种属间
MYD88 Q99836 q8yf33_brume Brucella melitensis biotype 1 Q8YF33
SLC
22155231
种属间
MYD88 Q99836 Q03463-PRO_0000278740 Hepatitis C virus Q03463-PRO_0000278740
Anti Tag CoIP
17567694
种属间: 跨种属相互作用 种属内: 同种属相互作用

MYD88 抗体

目录号 产品名 应用 反应物种
HY-P80760 MyD88 Antibody ICC/IF, WB, IHC-F, IHC-P, ELISA Human, Mouse, Rat

关联疾病

疾病名称 别名
Lymphoma, Non-Hodgkin, Familial

Non-Hodgkin Lymphoma

Lymphoma, Non-Hodgkin

NHL

Lymphoma, Non-Hodgkin, Somatic

Lymphoma, Follicular, Somatic

Familial Non-Hodgkin Lymphoma

Lymphoma Non-Hodgkins

Follicular Lymphoma, Somatic

Lymphosarcoma

Non-Hodgkins Lymphoma

Lymphoma

Lymphoid Cancer

Lymphomas

Lymphoid Cancers

Lymphoid Neoplasm

Lymphoma Nos

Nhl - [Non-Hodgkin Lymphoma]

Non-Hodgkin Lymphoma

Non-Hodgkin Lymphoma, Nos

Non-Hodgkin Malignant Lymphoma Nos

Myeloma, Multiple

Multiple Myeloma

Kahler Disease

Myelomatosis

Plasma Cell Myeloma

Medullary Plasmacytoma

Multiple Myeloma, Resistance To

Myeloma

Plasma Cell Dyscrasia

Multiple Myeloma, Susceptibility To

Myeloma - Multiple

Kahler'S Disease

Kahler-Bozzolo Disease

Plasma Cell Myelomas

MM

Plasma Cell Neoplasm

Primary Systemic Amyloidosis

Primary Amyloidosis

Immunoglobulin Deposition Disease

Plasmacytic Myeloma

Multiple Myelomata

Multiple Myeloma Nos

Multiple Myeloma Without Mention Of Remission

Monostotic Plasma Cell Myeloma

Mm - [Multiple Myeloma]

Parasitic Protozoa Infectious Disease

Protozoan Infections

Mastigophora Infectious Disease

Sarcomastigophora Infectious Disease

Superficial Basal Cell Carcinoma

Multifocal Superficial Basal Cell Carcinoma

Multicentric Basal Cell Carcinoma

Superficial Multicentric Basal-Cell Carcinoma

Paracoccidioidomycosis

Mucocutaneous-Lymphangitic Paracoccidioidomycosis

Paracoccidioidal Mycosis

Lobo Disease

Lutz-Splendore-Almeida Disease

Pcm

Paracoccidioidal Granuloma

South American Blastomycosis

Lobomycosis

Brazilian Blastomycosis

Lutz Disease

Brazilian Blastomycotic

South American Blastomyces Infection

Paracoccidioides Brasiliensis Infection

Paracoccidioidomycosis Unspecified

Tularemia

Francisella Tularensis Infection

Deerfly Fever

Lemming Fever

Ohara Disease

Pahvant Valley Plague

Rabbit Fever

Yatobyo

Perinatal Necrotizing Enterocolitis

Necrotizing Enterocolitis

Enterocolitis Necrotizing

Enterocolitis, Necrotizing

Necrotizing Enterocolitis In Fetus Or Newborn

Perinatal Necrotising Enterocolitis

Pseudomembranous Enterocolitis In Newborn

Nec

Coccidiosis

Intestinal Coccidiosis

Enteric Coccidiosis

Salmonellosis

Salmonella Infections

Salmonella Infection

Skin Disease

Skin Diseases

Abnormality Of The Skin

Skin Diseases, Genetic

Genodermatosis

Skin And Subcutaneous Tissue Disease

Dermatologic Disorders

Commensal Bacterial Infectious Disease
Lichen Sclerosus Et Atrophicus

Lichen Sclerosus

LSA

Lichen Sclerosis

Lichen Sclerosis Et Atrophicus

Ls Et A - [Lichen Sclerosus Et Atrophicus]

Lichen Albus

B-Cell Lymphoma

Lymphoma, B-Cell

B-Cell Lymphomas

B-Cell Lymphocytic Neoplasm

Lymphoma B-Cell

B-Cell Lymphoma Nos

X-Linked Immunodeficiency 74

Immunodeficiency 74, Covid-19-Related, X-Linked

Imd74

Respiratory Insufficiency Due To Sars-Cov-2 Viral Infection

Tlr7 Deficiency

X-Linked Immunodeficiency 74,Covid-19-Related

Listeriosis

Listeria Infection

Infection By Listeria Monocytogenes

Listeria Monocytogenes Infection

Listeria Infections

Listerial Foodborne Infection

Circling Disease

Infection Due To Listeria Monocytogenes

Listerellosis

Autoimmune Disease Of Gastrointestinal Tract
Macroglobulinemia, Waldenstrom 1

Macroglobulinemia, Waldenstrom, Somatic

WM1

Macroglobulinemia, Waldenstrom, Susceptibility To, 1

Macroglobulinemia, Waldenstrom, 1

Colonic Benign Neoplasm

Colon Neoplasm

Colonic Mass

Colonic Tumor

Neoplasm Of Colon

Neoplasm Of The Colon

Colonic Neoplasms

Colon Cancer

Colon Carcinoma Nos

Colonic Cancer

Metastatic Colon Cancer Nos

Rosacea

Erythematotelangiectatic Rosacea

Papulopustular Rosacea

Phymatous Rosacea

Acne Roscea

Acne, Erythematosa

Granulomatous Rosacea

Ocular Rosacea

Acne Rosacea

Hypertrophic Rosacea

Toxoplasmosis

Disseminated Toxoplasmosis

Multisystemic Disseminated Toxoplasmosis

Acquired Toxoplasmosis

Toxoplasmosis Disease Or Disorder

Infection By Toxoplasma Gondii

Toxoplasmal

Toxoplasma

Leukemia, Chronic Lymphocytic

Chronic Lymphocytic Leukemia

B-Cell Chronic Lymphocytic Leukemia

CLL

B-Cell Chronic Lymphoid Leukemia

Chronic Lymphatic Leukemia

Chronic Lymphocytic Leukaemia

Lymphoplasmacytic Leukemia

Small Lymphocytic Lymphoma

Leukemia, Chronic Lymphatic

B-Cell Chronic Lymphocytic Leukaemia

Chronic Lymphatic Leukaemia

Lymphoplasmacytic Leukaemia

B Cell Chronic Lymphocytic Leukemia

Chronic B-Cell Lymphocytic Leukemia

Leukemia, Lymphocytic, Chronic

B-Cll

Chronic Lymphoid Leukemia

Leukemia Lymphocytic Chronic

Lymphoma Small Lymphocytic

Leukemia, Lymphocytic, Chronic, B-Cell

Legionellosis

Legionella Infection

Pontiac Fever

Legionnaires' Disease

Infection By Legionella Pneumophilia

Legionella Pneumophila Infection

Macroglobulinemia

Primary Macroglobulinemia

Waldenstrom Macroglobulinemia

Visceral Leishmaniasis

Kala-Azar

Leishmaniasis, Visceral

Infection By Visceral Leishmaniasis

Leishmaniasis Visceral

Sahib Disease

Ponos

Burdwan Fever

Mard El Bicha

Sirkari Disease

Indian Visceral Leishmaniasis

Dumdum Fever

Visceral Leishmaniasis Due To Leishmania Donovani

Mantle Cell Lymphoma

Lymphoma, Mantle Cell

Lcm

Mcl

Mantle Zone Lymphoma

Lymphoma Mantle-Cell

Lymphoma, Mantle-Cell

Malignant Lymphoma, Lymphocytic, Intermediate Differentiation, Diffuse

Malignant Lymphoma - Lymphocytic, Intermediate Differentiation

Diffuse Small Cleaved-Cell Lymphoma

Diffuse Small Cleaved Cell Malignant Lymphoma

Small Cleaved Cell Non-Hodgkin Lymphoma

Diffuse Non-Hodgkin Small Cleaved Cell Lymphoma

Malignant Lymphomatous Polyposis

Malignant Small Cell, Noncleaved, Diffuse Lymphoma

Malignant Undifferentiated Cell, Non-Burkitt Lymphoma

Cleaved Cell Lymphoma

Small Cell Mantle Cell Lymphoma

Small Cleaved Cell Malignant Lymphoma

Eye Lymphoma

Malignant Lymphoma Of Eye

Lymphoma Of Eye

Opportunistic Mycosis

Opportunistic Mycoses

Opportunistic Systemic Mycoses

Intraocular Lymphoma

Primary Intraocular Lymphoma

Piol

Primary Intraocular Non-Hodgkin Lymphoma

Primary Intraocular Non-Hodgkin Malignant Lymphoma

Diffuse Large B-Cell Lymphoma

Dlbcl

Diffuse Large B-Cell Lymphoma, Not Otherwise Specified

Large B-Cell Diffuse Lymphoma

Lymphoma, Large B-Cell, Diffuse

Dlbcl - [Diffuse Large B-Cell Lymphoma]

Diffuse Large Beta Cell Lymphoma

Testicular Lymphoma

Malignant Lymphoma Of Testis

Lymphoma Of The Testis

Central Nervous System Lymphoma

Microglioma

Primary Cns Lymphoma

Cns Lymphoma

Primary Central Nervous System Lymphoma

Fungal Infectious Disease

Mycoses

Mycosis

Cystic Fibrosis

Mucoviscidosis

CF

Pseudomonas Aeruginosa, Susceptibility To Chronic Infection By, In Cystic Fibrosis

Pseudomonas Aeruginosa Chronic Infection By, In Cystic Fibrosis

Cystic Fibrosis Lung Disease, Modifier Of

Cystic Fibrosis Of Pancreas

Fibrocystic Disease Of Pancreas

Cf - [Cystic Fibrosis]

Cystic Fibrosis Nos

Fibrocystic Disease

Fibrocystic Disease Of The Pancreas

Mucoviscidosis Of Pancreas

Nonproliferative Fibrocystic Disease

Pancreatic Cystic Fibrosis

Bacterial Sepsis
Viral Infectious Disease

Arbovirus Infections

Viral Disease

Virus Infection

Virus Diseases

Viral Infection

Viral Infections

Virus Infections

Silo Filler'S Disease

Silo Filler Disease

Silo-Fillers' Disease

Thrombocytopenia

Low Platelet Count

Low Platelets

Decreased Platelets

Platelet Dysfunction Nos

Peritonitis

Retractile Mesenteritis

Sclerosing Mesenteritis

Acute Generalized Peritonitis

Primary Bacterial Peritonitis

Idiopathic Sclerosing Mesenteritis

Mesenteric Panniculitis

Peritoneal Retractile Mesenteritis

Liposclerotic Mesenteritis

Mesenteric Fibromatosis

Mesenteric Lipodystrophy

Mesenteric Lipogranuloma

Fibromatosis, Abdominal

Peritoneum Inflammation

Peritonitis Of Undetermined Cause

Peritonitis Of Unspecified Cause

Pelviperitonitis

Pelvic Peritonitis, Nos

Generalised Peritonitis Nos

Abdominal Peritonitis

Acute Idiopathic Peritonitis

Acute Lesser Sac Peritonitis

Acute Peritoneal Inflammation

Diffuse Peritonitis

Peritoneal Inflammation

Acute Primary Peritonitis

Pneumococcal Peritonitis

Retina Lymphoma

Lymphoma Of Retina

Retinal Lymphoma

Malaria

Malaria, Susceptibility To

Malaria, Resistance To

Malaria, Cerebral

Cerebral Malaria

Malaria, Severe, Susceptibility To

Malaria, Severe, Resistance To

Malaria, Cerebral, Susceptibility To

Induced Malaria

Malaria, Vivax, Protection Against

Malaria, Severe

Malaria, Cerebral, Reduced Risk Of

Malaria, Protection Against

Resistance To Malaria Due To G6pd Deficiency

Malaria Due To G6pd Deficiency

Malarial Encephalitis

CM

Malaria Cerebral

Susceptibility To Malaria

Acute Pernicious Fever

Aestivo-Autumnal Fever

Aestivo Autumnal Malaria

Chagres Fever

Continued Malaria Fever

Estivo-Autumnal Fever

Estivo-Autumnal Malaria

Estivo-Autumnal Malarial Fever

Falciparum Fever

Malignant Tertian Fever

Malignant Tertian Malaria

Pernicious Intermittent Fever

Pernicious Malaria

Quotidian Malaria

Subtertian Fever

Subtertian Malaria Fever

Subtertian Malignant Tertian Malaria

Tropical Malaria

Algid Malaria

Bilious Haemoglobinuric Fever

Black Water Fever

Blackwater Fever

Malarial Blackwater Fever

Severe Malarial Falciparum

West African Fever

Malarial Haematinuria

Haemoglobinuric Fever

Haemoglobinuric Malaria

Severe Plasmodium Falciparum Malaria

Malarial Haemoglobinuria

Malarial Haematuria

Falciparum Malaria [Malignant Tertian]

Malaria Tropica

Malarial Shock

Chagres Virus Disease

Malignant Malaria

Mtm - [Malignant Tertian Malaria]

Tm -[Malignant Tertian Malaria]

Panama Fever

St - [Subtertian Malaria]

Malarial Quotidian

Benign Tertian Malaria

Tertian Ague

Vivax Fever

Plasmodium Vivax Malaria Nos

Btm - [Benign Tertian Malaria]

Bt - [Benign Tertian Malaria]

Vivax Malaria

Benign Tertian Vivax Malaria

Tertian Malaria

Quartan Malaria

Quartan Ague

Quartan Fever

Plasmodium Malariae Malaria Nos

Quartan Malarial

Malaria By Plasmodium Malariae

Malariae Malaria

Ovale Tertian Malaria

Plasmodium Ovale Fever

Malaria Fever By Plasmodium Ovale

Ovale Malaria

Malaria By Plasmodium Ovale

Malarial Ovale

Marsh Fever

Remittent Congestive Fever

Coastal Fever

Remittent Gastric Fever

Miasmatic Fever

Congestive Remittent Fever

Intermittent Fever

Jungle Fever

Paludism

Cameroon Fever

Ague

Corsican Fever

Intermittent Bilious Fever

Disease Due To Plasmodiidae

Malarial Fever

Plasmodiosis

Remittent Fever

Roman Fever

Malaria Fever Nos

Malaria Nos

Paludal Fever

Clinically Diagnosed Malaria

Clinically Diagnosed Malaria Without Parasitological Confirmation

Congestive Fever

Malarial Cachexia

Marsh Cachexia

Paludal Cachexia

Recurrent Malaria

Remittent Malaria

Autoimmune Disease

Autoimmune Diseases

Autoimmune Hypersensitivity Disease

Hypersensitivity Reaction Type Ii Disease

Type Ii Hypersensitivity Reaction Disease

Heavy Chain Disease

Hcd

Pneumonic Tularemia

Pulmonary Tularemia

Bronchopneumonic Tularemia

Pneumonic Tularaemia

Celiac Disease 1

Celiac Disease

Coeliac Disease

Celiac Sprue

Celiac Disease, Susceptibility To

Gluten-Sensitive Enteropathy

Nontropical Sprue

Sprue

CELIAC1

Celiac Disease, Susceptibility To, 1

Celiac Sprue 1

Celiac Sprue, Susceptibility To, 1

Gluten-Sensitive Enteropathy 1

Gluten-Sensitive Enteropathy, Susceptibility To, 1

Idiopathic Steatorrhea

Cœliac Disease

Gluten Intolerance

Gluten-Induced Enteropathy

Gluten Enteropathy

Celiac Disease, Susceptibility To, Type 1

Childhood Celiac Disease

Coeliac Rickets

Gee Disease

Gee-Herter Disease

Heubner-Herter Disease

Idiopathic Steatorrhoea

Thaysen'S Disease

Herter Gee Syndrome

Plasma Protein Metabolism Disease
Mycobacterium Tuberculosis 1

Tuberculosis

Tuberculosis, Susceptibility To

Tuberculoma

Mycobacterium Tuberculosis, Susceptibility To, 1

Mtbs1

TB

Measles

Rubeola

Morbilli

Measles Nos

Koplik Spots

Glanders

Farcy Pipes

Infection Due To Pseudomonas Mallei

Burkholderia Mallei

Burkholderia Mallei Infection

Equina

Equine Glanders

Farcy

Farcy Buds

Farcy Cords

Infection Due To Actinobacillus Mallei

Infection Due To Malleomyces Mallei

Maliasmus

Malleus

Farce

Actinobacillosis

Actinobacillus Infection

Plasma Cell Neoplasm

Plasma Cell Dyscrasia

Paraproteinemias

Plasma Cell Tumour

Plasmacytic Tumor

Multiple Myeloma

Plasmacytoma

Plasma Cell Tumours

Plasma Cells Dyscrasia

Bacterial Infectious Disease

Bacterial Infections

Bacterial Infection Nos

Disease Caused By Bacteria

Bacterial Disease Or Disorder

Q Fever

Infection Due To Coxiella Burnetii

Quadrilateral Fever

Query Fever

Nine Mile Fever

Coxiella Burnetii Fever

Q Fever Pneumonia

Coxiellosis

Pneumonia In Q Fever

Australian Q Fever

Balkan Grippe

Primary Central Nervous System Lymphoma

Pcnsl

Primary Cns Lymphoma

Primary Brain Lymphoma

Primary Lymphoma, Cns

Primary Cerebral Lymphoma

Lipoprotein Quantitative Trait Locus

Coronary Artery Disease

Coronary Artery Disease, Susceptibility To

Coronary Artery Anomaly

Myocardial Ischemia

Congenital Anomaly Of Coronary Artery

Coronary Arteriosclerosis

Coronary Disease

Coronary Heart Disease

Coronary Artery Disorder

LPAQTL

Lpa Deficiency, Congenital

Coronary Artery Abnormality

Coronary Artery Anomaly, Congenital

Chd

Coronary Syndrome

Congenital Malformations Of Coronary Vessels

Malformation Of Coronary Vessels

Congenital Coronary Artery Anomaly

Congenital Coronary Artery Deformity

Congenital Coronary Artery Disorder

Abnormal Coronary Artery

Congenital Coronary Artery Malposition

Congenital Coronary Disease

Congenital Anomaly Of Coronary Arteries

Splenic Disease

Splenic Diseases

Dyssplenism

Spleen Disease

Abnormality Of The Spleen

Spleen Diseases

Schnitzler Syndrome

Chronic Urticaria With Gammopathy

Chronic Urticaria With Macroglobulinemia

Chronic Urticaria With Gammapathy

Zebrafish Allergy

Danio Rerio Allergy

Human Monocytic Ehrlichiosis

Ehrlichiosis Chafeensis

Hme

Human Ehrlichial Infection, Human Monocytic Type

Nervous System Disease

Abnormality Of The Nervous System

Nervous System Diseases

Nervous System Disorder

Monoclonal Gammopathy Of Uncertain Significance

Monoclonal Gammopathy Of Undetermined Significance

Mgus

Mgus - [Monoclonal Gammopathy Of Undetermined Significance]

Monoclonal Gammopathy Nos

Iga Gammopathy

Monoclonal Gammoglobulinopathy

Lymphoplasmacytic Lymphoma

Waldenstrom Macroglobulinemia

Malignant Lymphoma - Lymphoplasmacytic

Waldenström Macroglobulinaemia

Waldenström Macroglobulinaemia Without Mention Of Remission

Idiopathic Macroglobulinaemia

Primary Macroglobulinaemia

Systemic Lupus Erythematosus

Lupus Nephritis

SLE

Disseminated Lupus Erythematosus

Systemic Lupus Erythematosus, Susceptibility To

Lupus Erythematosus, Systemic

Lupus Nephritis, Susceptibility To

Libman-Sacks Disease

Systemic Lupus Erythematosus Susceptibility To

Sle - Lupus Erythematosus, Systemic

Le Syndrome

Lupus

Lupus Erythematosus Systemic

Lupus Erythematosus, Systemic, Susceptibility To

Lupus Vulgaris

Lupus Erythematosus, Discoid

Lupus Erythematosus

Systemic Lupus Erythematosus Nos

Sle - [Systemic Lupus Erythematosus]

Hepatitis B

Chronic Hepatitis B

Hepatitis B Infection

Serum Hepatitis

HBV

Hepatitis B Chronic

Hbv, Susceptibility To

Hepatitis B, Chronic

Chronic Hepatitis B Without Delta Agent

Chronic Hbv - [Hepatitis B Virus] Infection

Hepatitis B Nos

Chronic Type B Viral Hepatitis

Hep B Nos

Crohn'S Disease

Crohn Disease

Pediatric Crohn'S Disease

Regional Enteritis

Crohn'S Disease Of Large Bowel

Enteritis, Granulomatous

Crohn'S Disease Of Colon

Granulomatous Colitis

Colitis, Granulomatous

Crohn'S Enteritis

Enteritis, Regional

Enteritis

Ileitis

Adenoviral Enteritis

Acute Gastroenteropathy Due To Norwalk Agent

Viral Gastroenteritis Due To Norwalk Agent

Winter Vomiting

Epidemic Winter Vomiting Disease

Small Round Structured Virus Enteritis

Epidemic Vomiting Syndrome

Epidemic Vomiting

Epidemic Nausea

Epidemic Viral Gastroenteritis Due To Norwalk Virus

Noroviral Enteritis

Crohn Disease Nos

Crohns

Cd - [Crohn'S Disease]

Regional Enteritis Of Bowel

Crohn'S Regional Enteritis

Cobble-Stone Appearance Of Intestine

Intestinal Ulcer And Erosion Due To Crohn Disease

Granulomatous Enteritis

Lymphocytic Choriomeningitis

Lcm

Lymphocytic Meningitis

Lymphocytic Choriomeningitis Virus Encephalomyelitis

Lymphocytic Meningoencephalitis

Non-Arthropod Borne Lymphocytic Choriomeningitis

Lcm - [Lymphocytic Choriomeningitis]

Benign Lymphocytic Meningitis

Meningitis Due To Lymphocytic Choriomeningitis Virus

Diabetes Mellitus

Diabetes

Primary Bacterial Infectious Disease
Bacterial Pneumonia

Gram-Negative Pneumonia

Pneumonia Due To Other Gram-Negative Bacteria

Pneumonia Bacterial

Pneumonia, Bacterial

Acute Bacillus Pneumonia

Acute Bacterial Pneumonia

Bacillus Double Pneumonia

Bacillus Pneumonia

Bacteria Pneumonia

Bacterial Double Pneumonia

Bacterial Lobar Pneumonia

Bacterial Purulent Pneumonia

Bronchopneumonia Due To Bacteria Other Than S. Pneumoniae And H. Influenzae

Legionnaire Disease

Legionnaires' Disease

Legionnaires Disease

Legionnaire Disease, Susceptibility To

Legionella

Legionella Pneumonia

Infection By Legionella Pneumophilia

Legionnaire'S Disease

Legionellosis

Legionaire Disease, Susceptibility To

Legionnaires Pneumonia

Splenic Marginal Zone Lymphoma

Smzl

Splenic Marginal Zone B-Cell Lymphoma

Plague

Yersiniosis

Yersinia Infections

Infection By Yersinia Pestis

Pasteurella Pestis Infection

Pestilential Fever

Yersinia Pestis Infection

Lymphoma, Mucosa-Associated Lymphoid Type

Malt Lymphoma

Gastric Lymphoma, Primary

Lymphoma, Malt, Somatic

Mucosa-Associated Lymphoid Tissue Lymphoma

Extranodal Marginal Zone B-Cell Lymphoma

MALTOMA

Marginal Zone B-Cell Lymphoma

Mucosa-Associated Lymphatic Tissue Lymphoma

Primary Gastric Lymphoma

Gastric Lymphoma

Familial Primary Gastric Lymphoma

Immunodeficiency 68

Myd88 Deficiency

Pyogenic Bacterial Infections Due To Myd88 Deficiency

IMD68

Myd88d

Bacterial Susceptibility Due To Tlr Signaling Pathway Deficiency

Pyogenic Bacterial Infections, Recurrent, Due To Myd88 Deficiency

Kawasaki Disease

Mucocutaneous Lymph Node Syndrome

Acute Febrile Mucocutaneous Lymph Node Syndrome

Kawasaki Syndrome

Kd

Infantile Polyarteritis

Kawasaki Disease, Susceptibility To

Acute Febrile Mcls

Kawasaki'S Disease

Mlns

KWD

Marginal Zone B-Cell Lymphoma

Marginal Zone Lymphoma

Mzl

Mucosa-Associated Lymphoid Tissue Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstrom Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstrom'S Macroglobulinaemia

Waldenstrom'S Syndrome

Waldenström Macroglobulinemia

Waldenstrom'S Macroglobulinemia

Wm

Waldenström'S Macroglobulinemia

Malignant Lymphoma - Lymphoplasmacytic

Congenital Toxoplasmosis

Toxoplasmosis, Congenital

Mother-To-Child Transmission Of Toxoplasmosis

Toxoplasma Embryofetopathy

Toxoplasma Embryopathy

Toxoplasmosis - Congen.

Toxoplasmosis Congenital

Bronchopneumonia

Lobular Pneumonia

Bronchial Pneumonia

Chest Infection - Bronchopneumonia

Central Nervous System Hematologic Cancer

Cns Hematopoietic Tumor

Hematopoietic Neoplasm Of Central Nervous System

Central Nervous System Hematopoietic Neoplasm

Inflammatory Bowel Disease

Inflammatory Bowel Diseases

Bowel Disease, Inflammatory

Spleen Cancer

Spleen Neoplasm

Splenic Neoplasm

Splenic Neoplasms

Malignant Splenic Tumor

Malignant Tumour Of Spleen

Tumor Of Spleen

Malignant Neoplasm Of Spleen

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus MYD88 RGD RGD:735043
Canis familiaris MYD88 VGNC VGNC:43531
Bos taurus MYD88 VGNC VGNC:31789
Mus musculus MYD88 MGD MGI:108005
Macaca mulatta MYD88 VGNC VGNC:84149
Felis catus MYD88 VGNC VGNC:102779
Others MYD88 NCBI