2. 一站式药筛
  3. 化合物库
  4. 生物活性化合物库系列
  5. 已知活性化合物库
  6. 靶点多样性化合物库
靶点多样性化合物库 - Targeted Diversity Library

Cat. No.: HY-L099

靶点多样性化合物库包含 2,312 种化合物，涵盖 1000 多种靶点及亚型，如GPCR蛋白家族、离子通道、多种激酶等。每种靶点及亚型精心挑选 1-3 种高活性高特异性小分子化合物，每种化合物的生物活性信息均有明确的文献报道，是一个精简且靶点覆盖全面的小分子化合物集合，可以以较低的成本进行相对全面的化合物筛选，是进行不同表型筛选的有效工具。

我们将在明确您的产品用途后，向符合资质的客户通过定制合成服务的方式提供 MCE 靶点多样性化合物库，我们为该库中的所有产品提供溶液包装或粉末包装。溶液包装中，2,278 个产品以 10 mM 浓度提供，33 个产品以 2 mM 浓度提供，1 个产品以 3 mg/mL 浓度提供。

溶液包装中，我们对于溶液状态稳定且溶解度不低于 10 mM 的产品，提供 10 mM 溶液；对于溶液状态稳定且溶解度介于 2~10 mM 的产品，我们提供 2 mM 溶液；对于溶液状态稳定、分子量不确定且溶解度不低于 3 mg/mL产品，我们提供 3 mg/mL 溶液。

  • 96-well Plate with Peelable Foil Seal
  • 384-well Microplate with Peelable Foil Seal
  • 96-well Storage Tubes with Rack
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MCE 顾客使用化合物库产品发表的文献

  • 生物活性
  • 产品详情
  • 化合物库组成

活性描述 & 特点

Biological Activity

•   A unique collection of 2,312 bioactive compounds covering more than 1000 targets and isoforms.

•   1-3 compounds with high potency and selectivity were carefully selected for each target and isoform.

•   Target diverse, medicinally active and cell permeable.

•   Bioactivity and safety confirmed by preclinical research and clinical trials. Some have been approved by FDA.

•   More detailed compound information with structure, IC50, and other chemical & biological data.

•   High purity and quality validated by NMR and LC/MS.

产品详情

Product Details

Formulation:

A collection of 2,312 Targeted Diversity compounds supplied as pre-dissolved Solutions or Solid.
Solution: 2,278 compounds supplied in 10 mM solution, 33 compounds supplied in 2 mM solution, 1 compounds supplied in 3 mg/mL solution.

Layout:

96-well storage tube or 96-well plate: 1st and 12th column are left empty.
384-well plate: the first two columns and the last two columns are left empty.
Compounds with different concentrations or dissolved in different solvents will be put on separate plates. This way of layout may increase the number of plates because there could be three solvents and three concentrations.
If you have other requirements, please let us know.

Container:

96- or 384-well Plate with Peelable Foil Seal; 96-well Format Sample Storage Tube With Screw Cap and Optional 2D Barcode.

Storage:

-80°C

Shipping:

Blue ice or dry ice

化合物库组成

Composition

CDK (42)

PI3K (41)

EGFR (25)

HIV (21)

mGluR (20)

CCR (19)

HDAC (19)

Akt (18)

VEGFR (18)

CXCR (17)

FGFR (16)

mAChR (16)

STAT (16)

HSP (15)

MMP (15)

PKC (14)

HCV (13)

IKK (13)

JAK (13)

PARP (12)

COX (11)

ERK (11)

GSK-3 (11)

mTOR (11)

PI4K (11)

Raf (11)

MEK (10)

PDGFR (10)

PPAR (10)

JNK (9)

LXR (9)

AMPK (8)

相关服务推荐
定制您专属的化合物库
  •  特定化合物
  •  化合物数量
  •  产品排布图
  •  浓度
  •  形式（固体或溶液）
  •  YES
联系专家定制
  • 96-well Plate with Peelable Foil Seal
  • 384-well Microplate with Peelable Foil Seal
  • 96-well Storage Tubes with Rack
  • 96-well Plate with Peelable Foil Seal
  • 384-well Microplate with Peelable Foil Seal
  • 96-well Storage Tubes with Rack

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    产品名称：
    Targeted Diversity Library
    目录号：
    HY-L099
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