1. Gene
  2. YAP1 - Yes1 associated transcriptional regulator Gene

YAP1 - Yes1 associated transcriptional regulator Gene

中文名称:Yes1 相关的转录调节因子

种属: Homo sapiens

同用名: YAP; YKI; COB1; YAP2; YAP-1; YAP65

基因 ID: 10413 | 基因类型: protein coding

关于 YAP1

Cytogenetic location: 11q22.1 Genomic coordinates (GRCh38): 11:102,110,447-102,233,424 (from NCBI)

This gene has 11 transcripts (splice variants), 213 orthologues, 1 paralogue and is associated with 4 phenotypes. Ubiquitous expression in thyroid (RPKM 45.0), endometrium (RPKM 38.7) and 23 other tissues.

功能概要

该基因编码 Hippo 信号通路的下游核效应子,参与发育、生长、修复和体内平衡。已知该基因作为该信号通路的转录调节因子在多种癌症的发生和发展中发挥作用,并可作为癌症治疗的潜在靶点。可变剪接导致编码不同异构体的多个转录变体。[RefSeq 提供,2013 年 8 月]

This gene encodes a downstream nuclear effector of the Hippo signaling pathway which is involved in development, growth, repair, and homeostasis. This gene is known to play a role in the development and progression of multiple cancers as a transcriptional regulator of this signaling pathway and may function as a potential target for Cancer treatment. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2013]

YAP1 基因产物(14)

mRNA Protein Name
XM_011542555.3 XP_011540857.1 transcriptional coactivator YAP1 isoform X5
NM_001282097.2 NP_001269026.1 transcriptional coactivator YAP1 isoform 6
NM_001195044.2 NP_001181973.1 transcriptional coactivator YAP1 isoform 3
XM_005271378.4 XP_005271435.1 transcriptional coactivator YAP1 isoform X1
NM_006106.5 NP_006097.2 transcriptional coactivator YAP1 isoform 2
XM_005271381.4 XP_005271438.1 transcriptional coactivator YAP1 isoform X3
NM_001282100.2 NP_001269029.1 transcriptional coactivator YAP1 isoform 8
NM_001282098.2 NP_001269027.1 transcriptional coactivator YAP1 isoform 5
NM_001282101.2 NP_001269030.1 transcriptional coactivator YAP1 isoform 9
NM_001195045.2 NP_001181974.1 transcriptional coactivator YAP1 isoform 4
XM_005271380.4 XP_005271437.1 transcriptional coactivator YAP1 isoform X2
NM_001130145.3 NP_001123617.1 transcriptional coactivator YAP1 isoform 1
XM_005271383.4 XP_005271440.1 transcriptional coactivator YAP1 isoform X4
NM_001282099.2 NP_001269028.1 transcriptional coactivator YAP1 isoform 7
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables DNA-binding transcription factor binding IPI
IPI: 通过物理相互作用推断
20123905 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
7644498 GOA
enables transcription cis-regulatory region binding IDA
IDA: 通过直接分析推断
18280240 GOA
enables transcription coactivator activity IDA
IDA: 通过直接分析推断
16772533 GOA
enables transcription coactivator activity IMP
IMP: 通过突变表型推断
20123905 GOA
enables transcription coregulator activity IDA
IDA: 通过直接分析推断
18158288 GOA
enables transcription corepressor activity IDA
IDA: 通过直接分析推断
18158288 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in DNA damage response IDA
IDA: 通过直接分析推断
18280240 GOA
involved in cellular response to gamma radiation IDA
IDA: 通过直接分析推断
18280240 GOA
involved in hippo signaling IDA
IDA: 通过直接分析推断
35429439 GOA
involved in negative regulation of cilium assembly IMP
IMP: 通过突变表型推断
25849865 GOA
involved in negative regulation of epithelial cell apoptotic process IMP
IMP: 通过突变表型推断
29403552 GOA
involved in negative regulation of fat cell differentiation IMP
IMP: 通过突变表型推断
29496737 GOA
involved in negative regulation of gene expression IMP
IMP: 通过突变表型推断
29403552 GOA
involved in negative regulation of transcription by RNA polymerase II IMP
IMP: 通过突变表型推断
25849865 GOA
involved in positive regulation of DNA-templated transcription IDA
IDA: 通过直接分析推断
20368466 GOA
involved in positive regulation of DNA-templated transcription IMP
IMP: 通过突变表型推断
20123905 GOA
involved in positive regulation of cell growth IDA
IDA: 通过直接分析推断
17974916 GOA
involved in positive regulation of epithelial cell proliferation IMP
IMP: 通过突变表型推断
29403552 GOA
involved in positive regulation of gene expression IMP
IMP: 通过突变表型推断
29403552 GOA
involved in positive regulation of osteoblast differentiation IMP
IMP: 通过突变表型推断
29496737 GOA
involved in positive regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
20123905 GOA
involved in protein-containing complex assembly IDA
IDA: 通过直接分析推断
20368466 GOA
involved in protein-containing complex assembly IMP
IMP: 通过突变表型推断
20123905 GOA
acts upstream of or within regulation of neurogenesis IDA
IDA: 通过直接分析推断
25433207 GOA
acts upstream of or within regulation of stem cell proliferation IDA
IDA: 通过直接分析推断
25433207 GOA
involved in response to progesterone IDA
IDA: 通过直接分析推断
16772533 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of TEAD-YAP complex IDA
IDA: 通过直接分析推断
20123905 GOA
part of TEAD-YAP complex IPI
IPI: 通过物理相互作用推断
25384421 GOA
located in cytoplasm IDA
IDA: 通过直接分析推断
17974916 GOA
located in cytosol IDA
IDA: 通过直接分析推断
30865227 GOA
is active in nucleus IDA
IDA: 通过直接分析推断
35429439 GOA
located in nucleus IDA
IDA: 通过直接分析推断
17974916 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

YAP1 蛋白结构

WW

WW: WW domain (173 - 202)

WW

WW: WW domain (232 - 261)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 504 a.a.
蛋白主名 其他名称

transcriptional coactivator YAP1

65 kDa Yes-associated protein

Yes associated protein 1

protein yorkie homolog

yes-associated protein 2

yes-associated protein YAP65 homolog

yorkie homolog

YAP1 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
YAP1 P46937 NHERF2 Homo sapiens Q15599
Anti Tag CoIP
24255178
种属内
YAP1 P46937 PRKAA1 Homo sapiens Q13131
Anti Tag CoIP
25751140
种属内
YAP1 P46937 PRKAA1 Homo sapiens Q13131
TAP
25751139
种属内
YAP1 P46937 PTPN14 Homo sapiens Q15678
Anti Tag CoIP
24255178
种属内
YAP1 P46937 PTPN14 Homo sapiens Q15678
Anti Tag CoIP
24366813
种属内
YAP1 P46937 PTPN14 Homo sapiens Q15678
ITC
25283809
种属内
YAP1 P46937 PTPN14 Homo sapiens Q15678
TAP
25751139
种属内
YAP1 P46937 SMAD1 Homo sapiens Q15797
ITC
19914168
种属内
YAP1 P46937 SMAD1 Homo sapiens Q15797
Anti Tag CoIP
19914168
种属内
YAP1 P46937 TP63 Homo sapiens Q9H3D4
Phage Display
35044719
种属间
YAP1 P46937 Axin1 Mus musculus O35625
Anti Tag CoIP
24976009
种属内
YAP1 P46937 TP53BP2 Homo sapiens Q13625-2
Peptide Array
11278422
种属内
YAP1 P46937 TP53BP2 Homo sapiens Q13625-2
Y2H
11278422
种属内
YAP1 P46937 UVRAG Homo sapiens Q9P2Y5
Phage Display
37219487
种属内
YAP1 P46937 UVRAG Homo sapiens Q9P2Y5
Phage Display
35044719
种属内
YAP1 P46937 TBX5 Homo sapiens Q99593
CH-IP
23245941
种属内
YAP1 P46937 BTRC Homo sapiens Q9Y297
Anti Bait CoIP
24976009
种属内
YAP1 P46937 YWHAZ Homo sapiens P63104
Anti Tag CoIP
24255178
种属内
YAP1 P46937 YWHAZ Homo sapiens P63104
Pull Down
15161933
种属内
YAP1 P46937 TRERF1 Homo sapiens Q96PN7
Phage Display
37219487
种属内
YAP1 P46937 TRERF1 Homo sapiens Q96PN7
Phage Display
35044719
种属内
YAP1 P46937 YWHAE Homo sapiens P62258
TAP
25751139
种属内
YAP1 P46937 YWHAE Homo sapiens P62258
Anti Tag CoIP
24255178
种属内
YAP1 P46937 YWHAE Homo sapiens P62258
Pull Down
25751139
种属内
YAP1 P46937 YWHAE Homo sapiens P62258
Anti Tag CoIP
24366813
种属内
YAP1 P46937 YWHAB Homo sapiens P31946
Anti Tag CoIP
24255178
种属内
YAP1 P46937 YWHAB Homo sapiens P31946
Anti Tag CoIP
19439659
种属内
YAP1 P46937 YWHAB Homo sapiens P31946
Anti Tag CoIP
24366813
种属内
YAP1 P46937 YWHAB Homo sapiens P31946
CoIP
20048001
种属内
YAP1 P46937 SMAD7 Homo sapiens O15105
ITC
25283809
种属内
YAP1 P46937 WBP1 Homo sapiens Q96G27
Phage Display
35044719
种属内
YAP1 P46937 WBP1 Homo sapiens Q96G27
ITC
25283809
种属内
YAP1 P46937 TP73 Homo sapiens O15350
ITC
25283809
种属内
YAP1 P46937 TP73 Homo sapiens O15350
Phage Display
37219487
种属内
YAP1 P46937 TP73 Homo sapiens O15350
Phage Display
35044719
种属内
YAP1 P46937 TP73 Homo sapiens O15350-1
Anti Bait CoIP
11278685
种属内
YAP1 P46937 TP73 Homo sapiens O15350-1
Lambda Phage
11278685
种属内
YAP1 P46937 PRRG4 Homo sapiens Q9BZD6
Phage Display
37219487
种属内
YAP1 P46937 PRRG4 Homo sapiens Q9BZD6
Phage Display
35044719
种属内
YAP1 P46937 LATS1 Homo sapiens O95835
Phage Display
35044719
种属内
YAP1 P46937 LATS1 Homo sapiens O95835
ITC
25283809
种属内
YAP1 P46937 LATS1 Homo sapiens O95835
Anti Tag CoIP
24366813
种属内
YAP1 P46937 LATS1 Homo sapiens O95835
Protein Kinase Assay
22863277
种属内
YAP1 P46937 LATS1 Homo sapiens O95835
TAP
25751139
种属内
YAP1 P46937 LATS1 Homo sapiens O95835
Anti Tag CoIP
24255178
种属内
YAP1 P46937 CTNNB1 Homo sapiens P35222
Anti Tag CoIP
22234184
种属内
YAP1 P46937 CTNNB1 Homo sapiens P35222
Anti Bait CoIP
24976009
种属内
YAP1 P46937 CTNNB1 Homo sapiens P35222
Anti Bait CoIP
21376238
种属内
YAP1 P46937 CTNNB1 Homo sapiens P35222
Anti Bait CoIP
23245941
种属内
YAP1 P46937 CTNNB1 Homo sapiens P35222
Pull Down
22234184
种属内
YAP1 P46937 MAP2K1 Homo sapiens Q02750
Anti Tag CoIP
24211253
种属内
YAP1 P46937 TEAD1 Homo sapiens P28347
Anti Tag CoIP
25751140
种属内
YAP1 P46937 TEAD1 Homo sapiens P28347
BioID
24255178
种属内
YAP1 P46937 TEAD1 Homo sapiens P28347
Anti Bait CoIP
24581491
种属内
YAP1 P46937 TEAD1 Homo sapiens P28347
Anti Bait CoIP
25751140
种属内
YAP1 P46937 TEAD1 Homo sapiens P28347
Anti Bait CoIP
22863277
种属内
YAP1 P46937 TEAD1 Homo sapiens P28347
TAP
25751139
种属间
YAP1 P46937 Wbp1 Mus musculus P97764
Filter Binding
7644498
种属间
YAP1 P46937 Wbp1 Mus musculus P97764
Filter Binding
9202023
种属内
YAP1 P46937 TEAD2 Homo sapiens Q15562
TAP
25751139
种属内
YAP1 P46937 AXIN1 Homo sapiens O15169
Anti Bait CoIP
24976009
种属内
YAP1 P46937 AXIN1 Homo sapiens O15169
Anti Tag CoIP
24976009
种属内
YAP1 P46937 TMEM139 Homo sapiens Q8IV31
Phage Display
35044719
种属内
YAP1 P46937 WBP2 Homo sapiens Q969T9
Anti Tag CoIP
24366813
种属内
YAP1 P46937 WBP2 Homo sapiens Q969T9
Anti Tag CoIP
24255178
种属内
YAP1 P46937 WBP2 Homo sapiens Q969T9
TAP
25751139
种属内
YAP1 P46937 WBP2 Homo sapiens Q969T9
ITC
25283809
种属间
YAP1 P46937 Prkaa1 Mus musculus Q5EG47
Pull Down
25751139
种属内
YAP1 P46937 RAB11A Homo sapiens P62491
Anti Bait CoIP
28468127
种属内
YAP1 P46937 DDX17 Homo sapiens Q92841
IF
24581491
种属内
YAP1 P46937 DDX17 Homo sapiens Q92841
Anti Bait CoIP
24581491
种属内
YAP1 P46937 DDX17 Homo sapiens Q92841
Anti Tag CoIP
24581491
种属内
YAP1 P46937 TEAD4 Homo sapiens Q15561
Anti Bait CoIP
24525233
种属内
YAP1 P46937 TEAD4 Homo sapiens Q15561
Pull Down
24525233
种属内
YAP1 P46937 TEAD4 Homo sapiens Q15561
Anti Tag CoIP
25751140
种属内
YAP1 P46937 TEAD4 Homo sapiens Q15561
Pull Down
25751139
种属内
YAP1 P46937 ERBB4 Homo sapiens Q15303
ITC
25283809
种属内
YAP1 P46937 PTCH1 Homo sapiens Q13635
ITC
25283809
种属内
YAP1 P46937 TEAD2 Homo sapiens Q15562-2
Validated Y2H
32296183
种属内
YAP1 P46937 PRRG2 Homo sapiens O14669
ITC
25283809
种属间
YAP1 P46937 M Rabies virus A3RM21
Phage Display
37100772
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
High Grade Ependymoma

Ependymal Neoplasm

Ependymal Tumors

Malignant Ependymoma

Ependymal Tumor

Anaplastic Ependymoma

Experimental Organism Malignant Ependymoma

Ependymoma Of Brain

Plasma Cell Neoplasm

Plasma Cell Dyscrasia

Paraproteinemias

Plasma Cell Tumour

Plasmacytic Tumor

Multiple Myeloma

Plasmacytoma

Plasma Cell Tumours

Plasma Cells Dyscrasia

Coloboma Of Macula

Coloboma

Congenital Ocular Coloboma

Microphthalmia, Isolated, With Coloboma

Agenesis Of Macula

Hereditary Macular Coloboma

Ocular Coloboma

Coloboma Of Eye

Macular Coloboma

Uveoretinal Coloboma

Eccrine Porocarcinoma

Eccrine Porocarcinoma Of Skin

Malignant Eccrine Poroma

Porocarcinoma

Sveinsson Chorioretinal Atrophy

SCRA

Atrophia Areata

Helicoid Peripapillary Chorioretinal Degeneration

Hpcd

Aa

Peripapillary Chorioretinal Degeneration, Icelandic Type

Helicoidal Peripapillary Chorioretinal Degeneration

Atrophy, Chorioretinal, Sveinsson

Neurofibroma

Neurofibromas

Neurofibromatoses

Nerve Sheath Tumors

Cleft Lip/Palate

Cleft Lip And Palate

Alveolar Cleft Lip And Palate

Cleft Lip-Alveolus-Palate Syndrome

Flp

Gastric Cancer

Stomach Cancer

Stomach Carcinoma

Gastric Carcinoma

Gastric Cancer, Somatic

Gastric Neoplasm

Carcinoma Of Stomach

Stomach Neoplasms

Malignant Neoplasm Of Stomach

Gastric Cancer Risk After H. Pylori Infection

Cancer Of The Stomach

Adult Stomach Cancer

Adult Stomach Carcinoma

GASC

Gastric Cancer Intestinal

Gastric Cancers

Gastric Carcinomas

Cancer, Gastric

Stomach Neoplasm

Malignant Neoplasm Of Body Of Stomach

Malignant Tumor Of Lesser Curve Of Stomach

Gastrocarcinoma Of Unspecified Site

Leather Bottle Stomach

Carcinoma Of Fundus Of Stomach

Cancer Of Fundus Of Stomach

Primary Malignant Neoplasm Of Body Of Stomach

Cancer Of Body Of Stomach

Primary Malignant Neoplasm Of Pyloric Antrum

Pyloric Antrum Cancer

Malignant Tumour Of Stomach

Epithelioid Hemangioendothelioma

Hemangioendothelioma Epithelioid

Epithelioid Hemangioendothelioma, Malignant

Cholangiocarcinoma

Cholangiocarcinoma, Susceptibility To

Extrahepatic Cholangiocarcinoma

Intrahepatic Cholangiocarcinoma

Chlc

Chlc, Susceptibility To

Cc

Cholangiocarcinoma Of Biliary Tract

Cholangiocellular Carcinoma

Distal Cholangiocarcinoma

Perihilar Cholangiocarcinoma

Bile Duct Cancer

Cca

Adult Primary Cholangiocellular Carcinoma

Bile Duct Carcinoma

Cerebral Ventricle Cancer

Cerebral Ventricle Neoplasms

Cerebral Ventricle Neoplasm

Intraventricular Tumor Of Brain

Spinocerebellar Ataxia 45

SCA45

Spinocerebellar Ataxia Type 45

Supratentorial Cancer

Supratentorial Neoplasms

Brain Neoplasm, Supratentorial

Malignant Supratentorial Tumor

Cancer, Supratentorial

Rela Fusion-Positive Ependymoma

Supratentorial C11orf95-Rela Fused Ependymoma

C11orf95 Fusion-Positive Supratentorial Ependymoma

Cerebral Cavernous Malformations

Cerebral Cavernous Malformation

Cavernous Malformations Of Cns And Retina

Cerebral Cavernous Malformation 1

Cavernous Angiomatous Malformations

Cerebral Capillary Malformations

CCM

Hyperkeratotic Cutaneous Capillary-Venous Malformations Associated With Cerebral Capillary Malformations

Familial Cavernous Angioma

Familial Cerebral Cavernous Malformation

Cerebral Cavernous Malformations 1

Cavernous Angioma, Familial

Cam

Cerebral Cavernous Malformations-1

Cavernoma

Cavernous Angioma

Central Nervous System Cavernous Hemangioma

Cerebral Cavernous Hemangioma

Familial Cavernous Hemangioma

Familial Cavernous Malformation

Familial Cerebral Cavernous Angioma

Intracerebral Cavernous Hemangioma

CCM1

Cavernous Hemangioma Of The Brain

Cerebral Cavernoma

Cerebral Cavernous Malformations, Type 1

Hemangioma, Cavernous, Central Nervous System

Hemangioma, Cavernous

Angioma, Cavernous

Malignant Pleural Mesothelioma

Malignant Mesothelioma Of Pleura

Pleural Malignant Mesothelioma

Childhood Angiosarcoma

Paediatric Angiosarcoma

Paediatric Hemangiosarcoma

Pediatric Angiosarcoma

Pediatric Hemangiosarcoma

Medulloblastoma

MDB

Cpnet

Localized Primitive Neuroectodermal Tumor

Classic Medulloblastoma

Desmoplastic/Nodular Medulloblastoma

Medulloblastoma With Extensive Nodularity

Desmoplastic Medulloblastoma

Medulloblastoma, Somatic

Medulloblastoma, Desmoplastic

Brain Medulloblastoma

Cns Pnet

Infratentorial Primitive Neuroectodermal Tumor

Mben

Medulloblastoma Desmoplastic

Neuroectodermal Tumors, Primitive

Medulloblastomas

Medulloblastoma, With Extensive Nodularity

Medulloblastoma Of Unspecified Site

Medullomyoblastoma Of Unspecified Site

Pilomatrixoma

Pilomatricoma

PTR

Epithelioma Calcificans Of Malherbe

Benign Pilomatricoma

Calcifying Epithelioma Of Malherbe

Pilomatricoma, Somatic

Benign Pilomatrixoma

Malherbe Calcifying Epithelioma

Cystadenocarcinoma
Hepatoblastoma
Posterior Fossa Ependymoma
Myeloma, Multiple

Multiple Myeloma

Kahler Disease

Myelomatosis

Plasma Cell Myeloma

Medullary Plasmacytoma

Multiple Myeloma, Resistance To

Myeloma

Plasma Cell Dyscrasia

Multiple Myeloma, Susceptibility To

Myeloma - Multiple

Kahler'S Disease

Kahler-Bozzolo Disease

Plasma Cell Myelomas

MM

Plasma Cell Neoplasm

Primary Systemic Amyloidosis

Primary Amyloidosis

Immunoglobulin Deposition Disease

Plasmacytic Myeloma

Multiple Myelomata

Multiple Myeloma Nos

Multiple Myeloma Without Mention Of Remission

Monostotic Plasma Cell Myeloma

Mm - [Multiple Myeloma]

Spinal Cord Ependymoma

Ependymal Neoplasm Of The Spinal Cord

Ependymoma Of Spinal Cord

Esophageal Cancer

Esophageal Carcinoma

Carcinoma Of Esophagus

Esophageal Squamous Cell Carcinoma, Somatic

Esophageal Carcinoma, Somatic

Esophagus Cancer

Gastric Cardia Adenocarcinoma

Esophageal Neoplasms

Esophageal Cancer, Somatic

Cancer Of Esophagus

Cancer Of Oesophagus

Carcinoma Of Oesophagus

Ca Lower Third Oesophagus

Ca Middle Third Oesophagus

Malignant Neoplasm Of Distal Third Of Esophagus

Malignant Neoplasm Of Lower Third Of Oesophagus

Malignant Neoplasm Of Middle Third Of Oesophagus

Malignant Neoplasm Of Proximal Third Of Esophagus

Malignant Neoplasm Of Upper Third Esophagus

Malignant Tumor Of Abdominal Esophagus

Malignant Tumor Of Distal Third Of Esophagus

Malignant Tumor Of Proximal Third Of Esophagus

Malignant Tumor Of The Middle Third Of The Esophagus

ESCR

Aerodigestive Tract Cancer

Escc

Esophageal Squamous Cell Carcinoma

Cancer, Esophageal

Malignant Neoplasm Of Esophagus

Squamous Cell Carcinoma Of Esophagus

Malignant Neoplasm Of Middle Third Of Esophagus

Retinitis Pigmentosa

RP

Rod-Cone Dystrophy

Autosomal Recessive Retinitis Pigmentosa

Non-Syndromic Retinitis Pigmentosa

Pericentral Pigmentary Retinopathy

Pigmentary Retinopathy

Tapetoretinal Degeneration

Rcd

Retinitis Pigmentosa Autosomal Recessive

ARRP

Retinitis Pigmentosa, Autosomal Recessive

Retinitis Pigmentosa 1

Neurofibromatosis, Type Ii

Neurofibromatosis 2

Neurofibromatosis, Type 2

NF2

Neurofibromatosis Type Ii

Bilateral Acoustic Neurofibromatosis

Banf

Acn

Central Neurofibromatosis

Neurofibromatosis, Central Type

Acoustic Schwannomas, Bilateral

Acoustic Neurinoma, Bilateral

Bilateral Acoustic Neurinoma

Bilateral Acoustic Schwannomas

Familial Acoustic Neuromas

Supratentorial Ependymoma
Melanoma, Uveal

Uveal Melanoma

Choroidal Melanoma

Melanoma Of Uvea

Iris Melanoma

Malignant Melanoma Of Choroid

Malignant Melanoma Of Iris

Microphthalmia

Microphthalmos

Isolated Anophthalmia-Microphthalmia Syndrome

Isolated Microphthalmia-Anophthalmia-Coloboma

Simple Microphthalmos

Clinical Anophthalmia

Isolated Anophthalmia - Microphthalmia

Isolated Pure Microphthalmia

Mac Spectrum

Microphthalmia-Anophthalmia-Coloboma Spectrum

Primitive Anophthalmia

Globe Of Eye Small

Small Eyeball

Hypoplasia Of Eye

Isolated Nanophthalmos

Rudimentary Eye

Dysplasia Of Eye

Anaplastic Ependymoma

Ependymoma, Anaplastic

Undifferentiated Ependymoma

Rhabdomyosarcoma
Huntington Disease

Huntington'S Disease

Huntington Chorea

HD

Huntington'S Chorea

Huntington Chronic Progressive Hereditary Chorea

Juvenile Huntington Disease

Chronic Progressive Chorea

Chronic Progressive Hereditary Chorea

Hc - [Huntington Chorea]

Hereditary Chorea

Progressive Hereditary Chorea

Intestinal Obstruction

Inspissated Milk Syndrome

Milk Curd Syndrome

Coloboma, Ocular, Autosomal Dominant

Coloboma, Ocular

Coloboma Of Iris, Choroid, And Retina

Coi

Coloboma, Uveoretinal

COAD

Ocular Coloboma

Uveoretinal Coloboma

Chronic Obstructive Airway Disease

Cerebrum Cancer

Cerebral Cancer

Neoplasm Of Cerebrum

Tumor Of Cerebrum

Malignant Neoplasm Of Cerebrum

Childhood Supratentorial Ependymoma

Paediatric Cerebral Ependymoma

Paediatric Supratentorial Ependymoblastoma

Paediatric Supratentorial Ependymoma

Pediatric Cerebral Ependymoma

Pediatric Supratentorial Ependymoblastoma

Pediatric Supratentorial Ependymoma

Eccrine Acrospiroma

Acrospiroma

Poroma

Eccrine Hidradenoma

Eccrine Hidradenoma Of Skin

Hidradenoma

Adenoma, Sweat Gland

Benign Neoplasm Of Sweat Gland

Eccrine Poroma

Histiocytoid Hemangioma

Angiolymphoid Hyperplasia With Eosinophilia

Epithelioid Haemangioma

Epithelioid Hemangioma

Eccrine Sweat Gland Cancer

Malignant Eccrine Skin Neoplasm

Malignant Eccrine Tumor

Eccrine Sweat Gland Neoplasm

Eccrine Skin Neoplasm

Eccrine Tumor

Eccrine Neoplasm

Malignant Eccrine Neoplasm

Coloboma, Ocular, With Or Without Hearing Impairment, Cleft Lip/Palate, And/Or Mental Retardation

Uveal Coloboma-Cleft Lip And Palate-Intellectual Disability

COB1

Coloboma-Microphthalmos Syndrome

Coloboma-Microphthalmos Syndrome Associated With Sensorineural Hearing Loss, Hematuria, And Cleft Lip/Palate

Uveal Coloboma-Cleft Lip/Palate-Mental Retardation Syndrome

Coloboma, Cleft Lip-Palate And Mental Retardation Syndrome

Ocular Coloboma With Or Without Hearing Impairment, Cleft Lip/Palate, And/Or Mental Retardation

Coloboma, Ocular, With Or Without Hearing Impairment, Cleft Lip/Palate, And/Or Intellectual Disability

Coloboma, Ocular, With/Without Hearing Impairment, Cleft Lip/Palate, And/Or Mental Retardation

Spinal Ependymoma, Mycn
Myxopapillary Ependymoma

Ependymoma Myxopapillary

Hepatocellular Carcinoma

Liver Cancer

Primary Liver Cancer

HCC

Hepatoma

Malignant Neoplasm Of Liver

Liver Neoplasms

Cancer, Hepatocellular

Liver Cell Carcinoma

Lcc

Hepatoblastoma, Somatic

Hepatic Cancer

Primary Malignant Neoplasm Of Liver

Rare Tumor Of Liver And Intrahepatic Biliary Tract

Hepatocellular Carcinoma, Somatic

Hepatocellular Carcinoma, Childhood Type, Somatic

Hepatocellular Cancer, Somatic

Ca Liver - Primary

Hepatic Neoplasm

Malignant Hepato-Biliary Neoplasm

Malignant Neoplasm Of Liver, Not Specified As Primary Or Secondary

Malignant Neoplasm Of Liver, Primary

Malignant Tumor Of Liver

Neoplasm Of Liver

Non-Resectable Primary Hepatic Malignant Neoplasm

Resectable Malignant Neoplasm Of Liver

Resectable Malignant Neoplasm Of The Liver

Primary Liver Carcinoma

Primary Malignant Liver Neoplasm

Primary Cancer Of Liver

Primary Tumor Of The Liver

Rare Tumor Of Liver And Ibt

Hepatocellular Cancer

Neoplasm Of The Liver

Hepatomas

Liver Neoplasm

Liver Carcinoma

Liver And Intrahepatic Biliary Tract Carcinoma

Malignant Hepatobiliary Neoplasm

Adult Primary Hepatocellular Carcinoma

Hepatoblastoma

Carcinoma Of Liver

Malignant Liver Tumour

Malignant Hepatic Tumour

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus YAP1 RGD RGD:1306035
Mus musculus YAP1 MGD MGI:103262
Felis catus YAP1 VGNC VGNC:105820
Macaca mulatta YAP1 VGNC VGNC:79018
Bos taurus YAP1 VGNC VGNC:57367
Canis familiaris YAP1 VGNC VGNC:49698
Others YAP1 NCBI