2. Gene
  3. TXN2 - thioredoxin 2 Gene

TXN2 - thioredoxin 2 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：硫氧还蛋白 2

种属: Homo sapiens

同用名: TXN; MTRX; TRX2; MT-TRX; COXPD29

基因 ID: 25828 | 基因类型: protein coding

关于 TXN2

Cytogenetic location: 22q12.3 Genomic coordinates (GRCh38): 22:36,467,046-36,481,640 (from NCBI)

This gene has 5 transcripts (splice variants), 207 orthologues, 4 paralogues and is associated with 2 phenotypes. Ubiquitous expression in adrenal (RPKM 39.7), kidney (RPKM 28.5) and 25 other tissues.

功能概要

该核基因编码硫氧还蛋白家族的线粒体成员，硫氧还蛋白家族是一组小型多功能氧化还原活性蛋白。编码的蛋白质可能在调节线粒体膜电位和防止氧化剂诱导的细胞凋亡方面发挥重要作用。[RefSeq 提供，2008 年 7 月]

This nuclear gene encodes a mitochondrial member of the thioredoxin family, a group of small multifunctional redox-active proteins. The encoded protein may play important roles in the regulation of the mitochondrial membrane potential and in protection against oxidant-induced Apoptosis. [provided by RefSeq, Jul 2008]

TXN2 基因产物(1)

mRNA Protein Name
NM_012473.4 NP_036605.2 thioredoxin, mitochondrial precursor

TXN2 蛋白结构

Thioredoxin

Thioredoxin: Thioredoxin (69 - 163)

  • 0
  • 100
  • 166 a.a.
蛋白主名 其他名称

thioredoxin, mitochondrial

mitochondrial thioredoxin

TXN2 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
TXN2 Q99757 KRT40 Homo sapiens Q6A162
Validated Y2H
25416956
种属内
TXN2 Q99757 KRT40 Homo sapiens Q6A162
Y2H Prey Pooling
25416956
种属内
TXN2 Q99757 KRT40 Homo sapiens Q6A162
Y2H Array
25416956
种属内
TXN2 Q99757 ODAD1 Homo sapiens Q96M63
Y2H Array
25416956
种属内
TXN2 Q99757 ODAD1 Homo sapiens Q96M63
Y2H Prey Pooling
25416956
种属内
TXN2 Q99757 FAM9B Homo sapiens Q8IZU0
Y2H Prey Pooling
25416956
种属内
TXN2 Q99757 FAM9B Homo sapiens Q8IZU0
Y2H Array
25416956
种属内
TXN2 Q99757 ZBTB14 Homo sapiens O43829
Validated Y2H
25416956
种属内
TXN2 Q99757 ZBTB14 Homo sapiens O43829
Y2H Array
25416956
种属内
TXN2 Q99757 ZBTB14 Homo sapiens O43829
Y2H Prey Pooling
25416956
种属内
TXN2 Q99757 MAGEA11 Homo sapiens P43364-2
Validated Y2H
25416956
种属内
TXN2 Q99757 q6zn96_human Homo sapiens Q6ZN96
Y2H Array
32296183
种属内
TXN2 Q99757 q6zn96_human Homo sapiens Q6ZN96
Y2H Prey Pooling
32296183
种属内
TXN2 Q99757 PPP1R16B Homo sapiens Q96T49
Y2H Prey Pooling
32296183
种属内
TXN2 Q99757 PPP1R16B Homo sapiens Q96T49
Y2H Array
32296183
种属内
TXN2 Q99757 BCAS2 Homo sapiens O75934
Y2H Prey Pooling
32296183
种属内
TXN2 Q99757 BCAS2 Homo sapiens O75934
Y2H Array
32296183
种属内
TXN2 Q99757 UQCC2 Homo sapiens Q9BRT2
Validated Y2H
32296183
种属内
TXN2 Q99757 UQCC2 Homo sapiens Q9BRT2
Y2H Array
32296183
种属内
TXN2 Q99757 UQCC2 Homo sapiens Q9BRT2
Y2H Prey Pooling
32296183
种属内
TXN2 Q99757 CHMP1A Homo sapiens Q9HD42
Validated Y2H
32296183
种属内
TXN2 Q99757 CHMP1A Homo sapiens Q9HD42
Y2H Array
32296183
种属内
TXN2 Q99757 CHMP1A Homo sapiens Q9HD42
Y2H Prey Pooling
32296183
种属内
TXN2 Q99757 MAGEB2 Homo sapiens O15479
Y2H Array
32296183
种属内
TXN2 Q99757 MAGEB2 Homo sapiens O15479
Y2H Prey Pooling
32296183
种属内
TXN2 Q99757 RBM45 Homo sapiens Q8IUH3-3
Y2H Prey Pooling
32296183
种属内
TXN2 Q99757 RBM45 Homo sapiens Q8IUH3-3
Y2H Array
32296183
种属内
TXN2 Q99757 TFIP11 Homo sapiens Q9UBB9
Y2H Prey Pooling
32296183
种属内
TXN2 Q99757 TFIP11 Homo sapiens Q9UBB9
Validated Y2H
32296183
种属内
TXN2 Q99757 TFIP11 Homo sapiens Q9UBB9
Y2H Array
32296183
种属内
TXN2 Q99757 GPRASP3 Homo sapiens Q6PI77
Y2H Prey Pooling
32296183
种属内
TXN2 Q99757 GPRASP3 Homo sapiens Q6PI77
Y2H Array
32296183
种属内
TXN2 Q99757 MTUS2 Homo sapiens Q5JR59-3
Y2H Prey Pooling
32296183
种属内
TXN2 Q99757 MTUS2 Homo sapiens Q5JR59-3
Y2H Array
32296183
种属内
TXN2 Q99757 AGTRAP Homo sapiens Q6RW13-2
Y2H Prey Pooling
32296183
种属内
TXN2 Q99757 AGTRAP Homo sapiens Q6RW13-2
Y2H Array
32296183
种属内
TXN2 Q99757 AP2B1 Homo sapiens P63010-2
Y2H Prey Pooling
32296183
种属内
TXN2 Q99757 AP2B1 Homo sapiens P63010-2
Y2H Array
32296183
种属内
TXN2 Q99757 LCN2 Homo sapiens P80188
Y2H Prey Pooling
32296183
种属内
TXN2 Q99757 LCN2 Homo sapiens P80188
Y2H Array
32296183
种属内
TXN2 Q99757 SCYL3 Homo sapiens Q8IZE3-2
Y2H Array
32296183
种属内
TXN2 Q99757 SCYL3 Homo sapiens Q8IZE3-2
Y2H Prey Pooling
32296183
种属内
TXN2 Q99757 GUCD1 Homo sapiens Q96NT3-2
Y2H Prey Pooling
32296183
种属内
TXN2 Q99757 GUCD1 Homo sapiens Q96NT3-2
Y2H Array
32296183
种属内
TXN2 Q99757 CRACR2B Homo sapiens Q8N4Y2-3
Y2H Prey Pooling
32296183
种属内
TXN2 Q99757 CRACR2B Homo sapiens Q8N4Y2-3
Y2H Array
32296183
种属内
TXN2 Q99757 KAZN Homo sapiens Q674X7-2
Y2H Prey Pooling
32296183
种属内
TXN2 Q99757 KAZN Homo sapiens Q674X7-2
Y2H Array
32296183
种属内
TXN2 Q99757 ZMYND12 Homo sapiens Q9H0C1
Validated Y2H
32296183
种属内
TXN2 Q99757 ZMYND12 Homo sapiens Q9H0C1
Y2H Prey Pooling
32296183
种属内
TXN2 Q99757 ZMYND12 Homo sapiens Q9H0C1
Y2H Array
32296183
种属内
TXN2 Q99757 ANKRD36B Homo sapiens Q8N2N9-4
Y2H Prey Pooling
32296183
种属内
TXN2 Q99757 ANKRD36B Homo sapiens Q8N2N9-4
Y2H Array
32296183
种属内
TXN2 Q99757 POMC Homo sapiens P01189
Y2H Array
32296183
种属内
TXN2 Q99757 POMC Homo sapiens P01189
Y2H Prey Pooling
32296183
种属内
TXN2 Q99757 CIB4 Homo sapiens A0PJX0
Y2H Array
32296183
种属内
TXN2 Q99757 CIB4 Homo sapiens A0PJX0
Y2H Prey Pooling
32296183
种属内
TXN2 Q99757 MYL9 Homo sapiens P24844-2
Y2H Prey Pooling
32296183
种属内
TXN2 Q99757 MYL9 Homo sapiens P24844-2
Y2H Array
32296183
种属内
TXN2 Q99757 CSTPP1 Homo sapiens Q9H6J7-2
Y2H Prey Pooling
32296183
种属内
TXN2 Q99757 CSTPP1 Homo sapiens Q9H6J7-2
Validated Y2H
32296183
种属内
TXN2 Q99757 CSTPP1 Homo sapiens Q9H6J7-2
Y2H Array
32296183
种属内
TXN2 Q99757 SCYL3 Homo sapiens Q8IZE3
Y2H Array
31515488
种属内
TXN2 Q99757 REEP6 Homo sapiens Q96HR9-2
Y2H Prey Pooling
32296183
种属内
TXN2 Q99757 REEP6 Homo sapiens Q96HR9-2
Y2H Array
32296183
种属内
TXN2 Q99757 MEOX2 Homo sapiens Q6FHY5
Y2H Array
32296183
种属内
TXN2 Q99757 MEOX2 Homo sapiens Q6FHY5
Y2H Prey Pooling
32296183
种属内
TXN2 Q99757 CDCA4 Homo sapiens Q9BXL8
Validated Y2H
32296183
种属内
TXN2 Q99757 CDCA4 Homo sapiens Q9BXL8
Y2H Array
32296183
种属内
TXN2 Q99757 CDCA4 Homo sapiens Q9BXL8
Y2H Prey Pooling
32296183
种属内
TXN2 Q99757 RBM45 Homo sapiens Q8IUH3
Y2H Array
25416956
种属内
TXN2 Q99757 RBM45 Homo sapiens Q8IUH3
Validated Y2H
25416956
种属内
TXN2 Q99757 HAUS1 Homo sapiens Q96CS2
Y2H Prey Pooling
32296183
种属内
TXN2 Q99757 SSNA1 Homo sapiens O43805
Y2H Prey Pooling
25416956
种属内
TXN2 Q99757 SSNA1 Homo sapiens O43805
Y2H Prey Pooling
32296183
种属内
TXN2 Q99757 SSNA1 Homo sapiens O43805
Y2H Array
25416956
种属内
TXN2 Q99757 SSNA1 Homo sapiens O43805
Y2H Array
32296183
种属内
TXN2 Q99757 MIPOL1 Homo sapiens Q8TD10
Y2H Prey Pooling
32296183
种属内
TXN2 Q99757 MIPOL1 Homo sapiens Q8TD10
Y2H Array
32296183
种属内
TXN2 Q99757 HAUS8 Homo sapiens Q9BT25
Y2H Array
32296183
种属内
TXN2 Q99757 HAUS8 Homo sapiens Q9BT25
Y2H Prey Pooling
32296183
种属内
TXN2 Q99757 HAUS8 Homo sapiens Q9BT25
Validated Y2H
32296183
种属内
TXN2 Q99757 VPS52 Homo sapiens Q8N1B4
Y2H Prey Pooling
25416956
种属内
TXN2 Q99757 VPS52 Homo sapiens Q8N1B4
Y2H Prey Pooling
32296183
种属内
TXN2 Q99757 VPS52 Homo sapiens Q8N1B4
Y2H Array
25416956
种属内
TXN2 Q99757 VPS52 Homo sapiens Q8N1B4
Y2H Array
32296183
种属内
TXN2 Q99757 KRT27 Homo sapiens Q7Z3Y8
Y2H Prey Pooling
32296183
种属内
TXN2 Q99757 KRT27 Homo sapiens Q7Z3Y8
Y2H Array
32296183
种属内
TXN2 Q99757 PSME3 Homo sapiens P61289
Y2H Prey Pooling
25416956
种属内
TXN2 Q99757 PSME3 Homo sapiens P61289
Validated Y2H
25416956
种属内
TXN2 Q99757 STUB1 Homo sapiens Q9UNE7
Y2H Prey Pooling
25416956
种属内
TXN2 Q99757 STUB1 Homo sapiens Q9UNE7
Validated Y2H
25416956
种属内
TXN2 Q99757 SPTA1 Homo sapiens P02549
Y2H Prey Pooling
32296183
种属内
TXN2 Q99757 SPTA1 Homo sapiens P02549
Y2H Array
32296183
种属内
TXN2 Q99757 AP2B1 Homo sapiens P63010
Y2H Prey Pooling
25416956
种属内
TXN2 Q99757 AP2B1 Homo sapiens P63010
Validated Y2H
25416956
种属内
TXN2 Q99757 GPRASP2 Homo sapiens Q96D09
Y2H
21988832
种属内
TXN2 Q99757 GPRASP2 Homo sapiens Q96D09
Y2H Prey Pooling
32296183
种属内
TXN2 Q99757 GPRASP2 Homo sapiens Q96D09
Y2H Array
32296183
种属内
TXN2 Q99757 GOLGA6L9 Homo sapiens A6NEM1
Y2H Prey Pooling
32296183
种属内
TXN2 Q99757 GOLGA6L9 Homo sapiens A6NEM1
Y2H Array
32296183
种属内
TXN2 Q99757 PEX19 Homo sapiens P40855
Y2H Prey Pooling
32296183
种属内
TXN2 Q99757 PEX19 Homo sapiens P40855
Y2H Array
32296183
种属内
TXN2 Q99757 GTPBP2 Homo sapiens Q9BX10
Validated Y2H
32296183
种属内
TXN2 Q99757 GTPBP2 Homo sapiens Q9BX10
Y2H Array
32296183
种属内
TXN2 Q99757 GTPBP2 Homo sapiens Q9BX10
Y2H Prey Pooling
32296183
种属内
TXN2 Q99757 SYCE1 Homo sapiens Q8N0S2
Y2H Prey Pooling
32296183
种属内
TXN2 Q99757 SYCE1 Homo sapiens Q8N0S2
Y2H Array
32296183
种属内
TXN2 Q99757 SAT1 Homo sapiens P21673
Y2H Prey Pooling
32296183
种属内
TXN2 Q99757 SAT1 Homo sapiens P21673
Y2H Array
32296183
种属内
TXN2 Q99757 ETHE1 Homo sapiens O95571
Y2H Prey Pooling
32296183
种属内
TXN2 Q99757 ETHE1 Homo sapiens O95571
Y2H Array
32296183
种属内
TXN2 Q99757 CGGBP1 Homo sapiens Q9UFW8
Validated Y2H
32296183
种属内
TXN2 Q99757 CGGBP1 Homo sapiens Q9UFW8
Y2H Prey Pooling
32296183
种属内
TXN2 Q99757 CGGBP1 Homo sapiens Q9UFW8
Y2H Array
32296183
种属内
TXN2 Q99757 MDFI Homo sapiens Q99750
Y2H Prey Pooling
32296183
种属内
TXN2 Q99757 MDFI Homo sapiens Q99750
Y2H Array
32296183
种属内
TXN2 Q99757 PPCDC Homo sapiens Q96CD2
Y2H Array
32296183
种属内
TXN2 Q99757 PPCDC Homo sapiens Q96CD2
Y2H Prey Pooling
32296183
种属内
TXN2 Q99757 MAPRE3 Homo sapiens Q9UPY8
Y2H Prey Pooling
32296183
种属内
TXN2 Q99757 MAPRE3 Homo sapiens Q9UPY8
Validated Y2H
25416956
种属内
TXN2 Q99757 MAPRE3 Homo sapiens Q9UPY8
Validated Y2H
32296183
种属内
TXN2 Q99757 MAPRE3 Homo sapiens Q9UPY8
Y2H Array
32296183
种属内
TXN2 Q99757 CEP70 Homo sapiens Q8NHQ1
Y2H Prey Pooling
32296183
种属内
TXN2 Q99757 CEP70 Homo sapiens Q8NHQ1
Y2H Array
32296183
种属内
TXN2 Q99757 MAPRE2 Homo sapiens Q15555
Validated Y2H
25416956
种属内
TXN2 Q99757 MAPRE2 Homo sapiens Q15555
Y2H Prey Pooling
32296183
种属内
TXN2 Q99757 MAPRE2 Homo sapiens Q15555
Y2H Array
25416956
种属内
TXN2 Q99757 MAPRE2 Homo sapiens Q15555
Y2H Array
32296183
种属内
TXN2 Q99757 TIFA Homo sapiens Q96CG3
Y2H Array
25416956
种属内
TXN2 Q99757 ABI3 Homo sapiens Q9P2A4
Y2H Prey Pooling
32296183
种属内
TXN2 Q99757 ABI3 Homo sapiens Q9P2A4
Validated Y2H
32296183
种属内
TXN2 Q99757 ABI3 Homo sapiens Q9P2A4
Y2H Array
32296183
种属内
TXN2 Q99757 TRIP6 Homo sapiens Q15654
Validated Y2H
25416956
种属内
TXN2 Q99757 DDIT3 Homo sapiens P35638
Y2H Array
32296183
种属内
TXN2 Q99757 DDIT3 Homo sapiens P35638
Y2H Prey Pooling
32296183
种属内
TXN2 Q99757 MTUS2 Homo sapiens Q5JR59
Y2H Array
25416956
种属内
TXN2 Q99757 MAGEA4 Homo sapiens P43358
Y2H Prey Pooling
32296183
种属内
TXN2 Q99757 MAGEA4 Homo sapiens P43358
Y2H Array
32296183
种属内
TXN2 Q99757 RPIA Homo sapiens P49247
Y2H Array
25416956
种属内
TXN2 Q99757 RPIA Homo sapiens P49247
Y2H Array
32296183
种属内
TXN2 Q99757 RPIA Homo sapiens P49247
Y2H Prey Pooling
25416956
种属内
TXN2 Q99757 RPIA Homo sapiens P49247
Y2H Prey Pooling
32296183
种属内
TXN2 Q99757 STN1 Homo sapiens Q9H668
Y2H Prey Pooling
32296183
种属内
TXN2 Q99757 STN1 Homo sapiens Q9H668
Validated Y2H
32296183
种属内
TXN2 Q99757 STN1 Homo sapiens Q9H668
Y2H Array
32296183
种属内
TXN2 Q99757 MRFAP1L1 Homo sapiens Q96HT8
Y2H Prey Pooling
25416956
种属内
TXN2 Q99757 MRFAP1L1 Homo sapiens Q96HT8
Validated Y2H
25416956
种属内
TXN2 Q99757 MRFAP1L1 Homo sapiens Q96HT8
Y2H Prey Pooling
32296183
种属内
TXN2 Q99757 MRFAP1L1 Homo sapiens Q96HT8
Y2H Array
25416956
种属内
TXN2 Q99757 MRFAP1L1 Homo sapiens Q96HT8
Y2H Array
32296183
种属内
TXN2 Q99757 REEP6 Homo sapiens Q96HR9
Y2H Prey Pooling
25416956
种属内
TXN2 Q99757 REEP6 Homo sapiens Q96HR9
Validated Y2H
25416956
种属内
TXN2 Q99757 REEP6 Homo sapiens Q96HR9
Y2H Array
25416956
种属内
TXN2 Q99757 FHL5 Homo sapiens Q5TD97
Y2H Array
32296183
种属内
TXN2 Q99757 FHL5 Homo sapiens Q5TD97
Y2H Prey Pooling
32296183
种属内
TXN2 Q99757 CCDC197 Homo sapiens Q8NCU1
Y2H Array
32296183
种属内
TXN2 Q99757 CCDC197 Homo sapiens Q8NCU1
Y2H Prey Pooling
32296183
种属内
TXN2 Q99757 TRIM21 Homo sapiens P19474
Y2H Prey Pooling
25416956
种属内
TXN2 Q99757 TRIM21 Homo sapiens P19474
Y2H Prey Pooling
32296183
种属内
TXN2 Q99757 TRIM21 Homo sapiens P19474
Y2H Array
32296183
种属内
TXN2 Q99757 TRIM21 Homo sapiens P19474
Validated Y2H
25416956
种属内
TXN2 Q99757 TTC32 Homo sapiens Q5I0X7
Y2H Prey Pooling
32296183
种属内
TXN2 Q99757 TTC32 Homo sapiens Q5I0X7
Y2H Array
32296183
种属内
TXN2 Q99757 RABGEF1 Homo sapiens Q9UJ41
Y2H Prey Pooling
25416956
种属内
TXN2 Q99757 TMOD4 Homo sapiens Q9NZQ9
Y2H Prey Pooling
32296183
种属内
TXN2 Q99757 TMOD4 Homo sapiens Q9NZQ9
Validated Y2H
32296183
种属内
TXN2 Q99757 TMOD4 Homo sapiens Q9NZQ9
Y2H Array
32296183
种属内
TXN2 Q99757 MRFAP1 Homo sapiens Q9Y605
Validated Y2H
32296183
种属内
TXN2 Q99757 MRFAP1 Homo sapiens Q9Y605
Y2H Prey Pooling
32296183
种属内
TXN2 Q99757 MRFAP1 Homo sapiens Q9Y605
Y2H Array
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

重组 TXN2 蛋白

目录号 产品名 蛋白编号 纯度
HY-P71393 TXN2 Protein, Human (His) Q99757 (T60-G166) ≥95%

TXN2 抗体

目录号 产品名 应用 反应物种
HY-P82447 Thioredoxin 2 Antibody (YA2192) WB, IHC-F, IHC-P, ICC/IF Human, Mouse, Rat

关联疾病

疾病名称 别名
Combined Oxidative Phosphorylation Deficiency 29

COXPD29

Combined Oxidative Phosphorylation Defect Type 29
Ocular Hypertension

Hypertension, Ocular

Intraocular Pressure Increase

Oh - [Ocular Hypertension]

Oht - [Ocular Hypertension]
Dystonia

Dystonic Disease

Dystonic Disorder

Dystonia Disorders

Neuroleptic Dyskinesia
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS15288 TXN2 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus TXN2 RGD RGD:71040
Canis familiaris TXN2 VGNC VGNC:48009
Bos taurus TXN2 VGNC VGNC:36533
Felis catus TXN2 VGNC VGNC:66723
Mus musculus TXN2 MGD MGI:1929468
Others TXN2 NCBI
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Y

Z

热 A B C F G H J L N Q S T X Y Z