2. Gene
  3. PLN - phospholamban Gene

PLN - phospholamban Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：受磷蛋白

种属: Homo sapiens

同用名: PLB; CMD1P; CMH18

基因 ID: 5350 | 基因类型: protein coding

关于 PLN

Cytogenetic location: 6q22.31 Genomic coordinates (GRCh38): 6:118,548,296-118,561,716 (from NCBI)

This gene has 1 transcript (splice variant), 187 orthologues and is associated with 5 phenotypes. Biased expression in heart (RPKM 615.2), gall bladder (RPKM 62.5) and 1 other tissue.

功能概要

由该基因编码的蛋白质被发现为五聚体，是心肌中 cAMP 依赖性蛋白激酶的主要底物。编码的蛋白质是未磷酸化状态下心肌肌浆网 CA (2+) -ATP 酶的抑制剂，但蛋白质磷酸化后抑制作用解除。 CA (2+) 泵的后续激活导致肌肉松弛率增强，从而有助于 β 激动剂在心脏中引起的正性肌力反应。编码的蛋白质是心脏舒张功能的关键调节剂。该基因的突变是遗传性人类扩张型心肌病伴难治性充血性心力衰竭以及家族性肥厚性心肌病的原因。[RefSeq 提供，2016 年 4 月]

The protein encoded by this gene is found as a pentamer and is a major substrate for the cAMP-dependent protein kinase in cardiac muscle. The encoded protein is an inhibitor of cardiac muscle sarcoplasmic reticulum CA(2+)-ATPase in the unphosphorylated state, but inhibition is relieved upon phosphorylation of the protein. The subsequent activation of the CA(2+) pump leads to enhanced muscle relaxation rates, thereby contributing to the inotropic response elicited in heart by beta-agonists. The encoded protein is a key regulator of cardiac diastolic function. Mutations in this gene are a cause of inherited human dilated cardiomyopathy with refractory congestive heart failure, and also familial hypertrophic cardiomyopathy. [provided by RefSeq, Apr 2016]

PLN 基因产物(1)

mRNA Protein Name
NM_002667.5 NP_002658.1 cardiac phospholamban
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables ATPase inhibitor activity IDA
IDA: 通过直接分析推断
19708671 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
15598648 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in negative regulation of ATP-dependent activity IDA
IDA: 通过直接分析推断
19708671 GOA
involved in negative regulation of ATPase-coupled calcium transmembrane transporter activity IDA
IDA: 通过直接分析推断
19708671 GOA
involved in negative regulation of calcium ion binding IDA
IDA: 通过直接分析推断
19708671 GOA
involved in negative regulation of calcium ion transmembrane transporter activity IDA
IDA: 通过直接分析推断
19708671 GOA
involved in negative regulation of calcium ion transport IDA
IDA: 通过直接分析推断
19708671 GOA
involved in negative regulation of heart rate IMP
IMP: 通过突变表型推断
16432188 GOA
involved in regulation of ATPase-coupled calcium transmembrane transporter activity IDA
IDA: 通过直接分析推断
22427649 GOA
involved in regulation of calcium ion transport IDA
IDA: 通过直接分析推断
22427649 GOA
involved in regulation of heart contraction IMP
IMP: 通过突变表型推断
16432188 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of calcium ion-transporting ATPase complex IDA
IDA: 通过直接分析推断
19708671 GOA
located in membrane IDA
IDA: 通过直接分析推断
19708671 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

PLN 蛋白结构

Phospholamban

Phospholamban: Phospholamban (1 - 52)

  • 0
  • 52 a.a.
蛋白主名 其他名称

cardiac phospholamban

PLN 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
PLN P26678 LDLRAD1 Homo sapiens Q5T700
Validated Y2H
32296183
种属内
PLN P26678 LDLRAD1 Homo sapiens Q5T700
Y2H Array
32296183
种属内
PLN P26678 LDLRAD1 Homo sapiens Q5T700
Y2H Prey Pooling
32296183
种属内
PLN P26678 LDLRAD1 Homo sapiens Q5T700
Y2H Array
24722188
种属内
PLN P26678 SDC3 Homo sapiens A0A0S2Z4U3
Y2H Array
32296183
种属内
PLN P26678 SDC3 Homo sapiens A0A0S2Z4U3
Y2H Prey Pooling
32296183
种属内
PLN P26678 SLC30A8 Homo sapiens Q8IWU4
Y2H Array
32296183
种属内
PLN P26678 SLC30A8 Homo sapiens Q8IWU4
Y2H Prey Pooling
32296183
种属内
PLN P26678 SLC30A8 Homo sapiens Q8IWU4
Validated Y2H
32296183
种属内
PLN P26678 LSMEM2 Homo sapiens Q8N112
Y2H Array
32296183
种属内
PLN P26678 LSMEM2 Homo sapiens Q8N112
Y2H Prey Pooling
32296183
种属内
PLN P26678 LSMEM2 Homo sapiens Q8N112
Validated Y2H
32296183
种属内
PLN P26678 SPAG4 Homo sapiens Q9NPE6
Validated Y2H
32296183
种属内
PLN P26678 SPAG4 Homo sapiens Q9NPE6
Y2H Array
32296183
种属内
PLN P26678 SPAG4 Homo sapiens Q9NPE6
Y2H Prey Pooling
32296183
种属内
PLN P26678 TMEM45A Homo sapiens Q9NWC5
Y2H Prey Pooling
32296183
种属内
PLN P26678 TMEM45A Homo sapiens Q9NWC5
Validated Y2H
32296183
种属内
PLN P26678 TMEM45A Homo sapiens Q9NWC5
Y2H Array
32296183
种属内
PLN P26678 MGST2 Homo sapiens Q99735
Y2H Prey Pooling
32296183
种属内
PLN P26678 MGST2 Homo sapiens Q99735
Validated Y2H
32296183
种属内
PLN P26678 MGST2 Homo sapiens Q99735
Y2H Array
32296183
种属内
PLN P26678 ARL13B Homo sapiens Q3SXY8
Y2H Prey Pooling
32296183
种属内
PLN P26678 ARL13B Homo sapiens Q3SXY8
Validated Y2H
32296183
种属内
PLN P26678 ARL13B Homo sapiens Q3SXY8
Y2H Array
32296183
种属内
PLN P26678 HIBADH Homo sapiens P31937
Validated Y2H
32296183
种属内
PLN P26678 HIBADH Homo sapiens P31937
Y2H Array
32296183
种属内
PLN P26678 HIBADH Homo sapiens P31937
Y2H Prey Pooling
32296183
种属内
PLN P26678 RTN3 Homo sapiens O95197-3
Y2H Array
32296183
种属内
PLN P26678 RTN3 Homo sapiens O95197-3
Y2H Prey Pooling
32296183
种属内
PLN P26678 GPX8 Homo sapiens Q8TED1
Y2H Prey Pooling
32296183
种属内
PLN P26678 GPX8 Homo sapiens Q8TED1
Validated Y2H
32296183
种属内
PLN P26678 GPX8 Homo sapiens Q8TED1
Y2H Array
32296183
种属内
PLN P26678 TMEM179B Homo sapiens Q7Z7N9
Y2H Prey Pooling
32296183
种属内
PLN P26678 TMEM179B Homo sapiens Q7Z7N9
Validated Y2H
32296183
种属内
PLN P26678 TMEM179B Homo sapiens Q7Z7N9
Y2H Array
32296183
种属内
PLN P26678 CLEC2D Homo sapiens Q9UHP7-3
Validated Y2H
32296183
种属内
PLN P26678 CLEC2D Homo sapiens Q9UHP7-3
Y2H Array
32296183
种属内
PLN P26678 CLEC2D Homo sapiens Q9UHP7-3
Y2H Prey Pooling
32296183
种属内
PLN P26678 MFF Homo sapiens Q9GZY8-5
Validated Y2H
32296183
种属内
PLN P26678 MFF Homo sapiens Q9GZY8-5
Y2H Prey Pooling
32296183
种属内
PLN P26678 MFF Homo sapiens Q9GZY8-5
Y2H Array
32296183
种属内
PLN P26678 STX2 Homo sapiens P32856-2
Validated Y2H
32296183
种属内
PLN P26678 STX2 Homo sapiens P32856-2
Y2H Array
32296183
种属内
PLN P26678 STX2 Homo sapiens P32856-2
Y2H Prey Pooling
32296183
种属内
PLN P26678 FNDC9 Homo sapiens Q8TBE3
Y2H Array
32296183
种属内
PLN P26678 FNDC9 Homo sapiens Q8TBE3
Y2H Prey Pooling
32296183
种属内
PLN P26678 FNDC9 Homo sapiens Q8TBE3
Validated Y2H
32296183
种属内
PLN P26678 TMPRSS2 Homo sapiens O15393-2
Y2H Prey Pooling
32296183
种属内
PLN P26678 TMPRSS2 Homo sapiens O15393-2
Y2H Array
32296183
种属内
PLN P26678 ASGR2 Homo sapiens P07307-3
Y2H Prey Pooling
32296183
种属内
PLN P26678 ASGR2 Homo sapiens P07307-3
Y2H Array
32296183
种属内
PLN P26678 SLC34A2 Homo sapiens O95436-2
Y2H Prey Pooling
32296183
种属内
PLN P26678 SLC34A2 Homo sapiens O95436-2
Y2H Array
32296183
种属内
PLN P26678 SLC39A2 Homo sapiens Q9NP94
Y2H Prey Pooling
32296183
种属内
PLN P26678 SLC39A2 Homo sapiens Q9NP94
Validated Y2H
32296183
种属内
PLN P26678 SLC39A2 Homo sapiens Q9NP94
Y2H Array
32296183
种属内
PLN P26678 ATP6V0E1 Homo sapiens O15342
Y2H Array
32296183
种属内
PLN P26678 ATP6V0E1 Homo sapiens O15342
Y2H Prey Pooling
32296183
种属内
PLN P26678 GPR152 Homo sapiens Q8TDT2
Validated Y2H
32296183
种属内
PLN P26678 GPR152 Homo sapiens Q8TDT2
Y2H Array
32296183
种属内
PLN P26678 GPR152 Homo sapiens Q8TDT2
Y2H Prey Pooling
32296183
种属内
PLN P26678 SLC14A2 Homo sapiens Q15849
Y2H Prey Pooling
32296183
种属内
PLN P26678 SLC14A2 Homo sapiens Q15849
Validated Y2H
32296183
种属内
PLN P26678 SLC14A2 Homo sapiens Q15849
Y2H Array
32296183
种属内
PLN P26678 MUC1 Homo sapiens P15941-11
Y2H Prey Pooling
32296183
种属内
PLN P26678 MUC1 Homo sapiens P15941-11
Y2H Array
32296183
种属内
PLN P26678 SLC35C2 Homo sapiens Q9NQQ7-3
Y2H Prey Pooling
32296183
种属内
PLN P26678 SLC35C2 Homo sapiens Q9NQQ7-3
Validated Y2H
32296183
种属内
PLN P26678 SLC35C2 Homo sapiens Q9NQQ7-3
Y2H Array
32296183
种属内
PLN P26678 GJA8 Homo sapiens P48165
Validated Y2H
32296183
种属内
PLN P26678 GJA8 Homo sapiens P48165
Y2H Array
32296183
种属内
PLN P26678 GJA8 Homo sapiens P48165
Y2H Prey Pooling
32296183
种属内
PLN P26678 SPACA1 Homo sapiens Q9HBV2
Y2H Array
32296183
种属内
PLN P26678 SPACA1 Homo sapiens Q9HBV2
Y2H Prey Pooling
32296183
种属内
PLN P26678 SPACA1 Homo sapiens Q9HBV2
Validated Y2H
32296183
种属内
PLN P26678 CPLX4 Homo sapiens Q7Z7G2
Validated Y2H
32296183
种属内
PLN P26678 CPLX4 Homo sapiens Q7Z7G2
Y2H Array
32296183
种属内
PLN P26678 CPLX4 Homo sapiens Q7Z7G2
Y2H Prey Pooling
32296183
种属内
PLN P26678 HSD17B13 Homo sapiens Q7Z5P4
Y2H Prey Pooling
32296183
种属内
PLN P26678 HSD17B13 Homo sapiens Q7Z5P4
Validated Y2H
32296183
种属内
PLN P26678 HSD17B13 Homo sapiens Q7Z5P4
Y2H Array
32296183
种属内
PLN P26678 PLPPR1 Homo sapiens Q8TBJ4
Y2H Prey Pooling
32296183
种属内
PLN P26678 PLPPR1 Homo sapiens Q8TBJ4
Validated Y2H
32296183
种属内
PLN P26678 PLPPR1 Homo sapiens Q8TBJ4
Y2H Array
32296183
种属内
PLN P26678 TMEM52B Homo sapiens Q4KMG9
Validated Y2H
32296183
种属内
PLN P26678 TMEM52B Homo sapiens Q4KMG9
Y2H Array
32296183
种属内
PLN P26678 TMEM52B Homo sapiens Q4KMG9
Y2H Prey Pooling
32296183
种属内
PLN P26678 FAM209A Homo sapiens Q5JX71
Validated Y2H
32296183
种属内
PLN P26678 FAM209A Homo sapiens Q5JX71
Y2H Array
32296183
种属内
PLN P26678 FAM209A Homo sapiens Q5JX71
Y2H Prey Pooling
32296183
种属内
PLN P26678 ELOVL4 Homo sapiens Q9GZR5
Validated Y2H
32296183
种属内
PLN P26678 ELOVL4 Homo sapiens Q9GZR5
Y2H Array
32296183
种属内
PLN P26678 ELOVL4 Homo sapiens Q9GZR5
Y2H Prey Pooling
32296183
种属内
PLN P26678 TMEM86B Homo sapiens Q8N661
Y2H Prey Pooling
32296183
种属内
PLN P26678 TMEM86B Homo sapiens Q8N661
Y2H Array
32296183
种属内
PLN P26678 TMEM86B Homo sapiens Q8N661
Validated Y2H
32296183
种属内
PLN P26678 TMEM106C Homo sapiens Q9BVX2
Y2H Array
32296183
种属内
PLN P26678 TMEM106C Homo sapiens Q9BVX2
Validated Y2H
32296183
种属内
PLN P26678 TMEM106C Homo sapiens Q9BVX2
Y2H Prey Pooling
32296183
种属内
PLN P26678 GPR37L1 Homo sapiens O60883
Y2H Prey Pooling
32296183
种属内
PLN P26678 GPR37L1 Homo sapiens O60883
Y2H Array
32296183
种属内
PLN P26678 SAR1A Homo sapiens Q9NR31
Y2H Array
32296183
种属内
PLN P26678 SAR1A Homo sapiens Q9NR31
Y2H Prey Pooling
32296183
种属内
PLN P26678 SAR1A Homo sapiens Q9NR31
Validated Y2H
32296183
种属内
PLN P26678 MFSD5 Homo sapiens Q6N075
Validated Y2H
32296183
种属内
PLN P26678 MFSD5 Homo sapiens Q6N075
Y2H Array
32296183
种属内
PLN P26678 MFSD5 Homo sapiens Q6N075
Y2H Prey Pooling
32296183
种属内
PLN P26678 TMEM45B Homo sapiens Q96B21
Y2H Prey Pooling
32296183
种属内
PLN P26678 TMEM45B Homo sapiens Q96B21
Validated Y2H
32296183
种属内
PLN P26678 TMEM45B Homo sapiens Q96B21
Y2H Array
32296183
种属内
PLN P26678 MTIF3 Homo sapiens Q9H2K0
Validated Y2H
32296183
种属内
PLN P26678 MTIF3 Homo sapiens Q9H2K0
Y2H Prey Pooling
32296183
种属内
PLN P26678 MTIF3 Homo sapiens Q9H2K0
Y2H Array
32296183
种属内
PLN P26678 EDA Homo sapiens Q92838
Y2H Array
32296183
种属内
PLN P26678 EDA Homo sapiens Q92838
Y2H Prey Pooling
25416956
种属内
PLN P26678 EDA Homo sapiens Q92838
Y2H Prey Pooling
32296183
种属内
PLN P26678 EDA Homo sapiens Q92838
Y2H Array
31515488
种属内
PLN P26678 EDA Homo sapiens Q92838
Y2H Bait-Prey Pool
25910212
种属内
PLN P26678 EDA Homo sapiens Q92838
Y2H Array
24722188
种属内
PLN P26678 EDA Homo sapiens Q92838
Y2H Array
25910212
种属内
PLN P26678 EDA Homo sapiens Q92838
Validated Y2H
25910212
种属内
PLN P26678 EDA Homo sapiens Q92838
Validated Y2H
32296183
种属内
PLN P26678 EDA Homo sapiens Q92838
Y2H Array
25416956
种属内
PLN P26678 CREB3 Homo sapiens O43889-2
Validated Y2H
25910212
种属内
PLN P26678 CREB3 Homo sapiens O43889-2
Y2H Bait-Prey Pool
25910212
种属内
PLN P26678 CREB3 Homo sapiens O43889-2
Y2H Array
25910212
种属内
PLN P26678 TMEM205 Homo sapiens Q6UW68
Y2H Array
32296183
种属内
PLN P26678 TMEM205 Homo sapiens Q6UW68
Y2H Prey Pooling
32296183
种属内
PLN P26678 TMEM205 Homo sapiens Q6UW68
Validated Y2H
32296183
种属内
PLN P26678 CD53 Homo sapiens P19397
Y2H Prey Pooling
32296183
种属内
PLN P26678 CD53 Homo sapiens P19397
Y2H Array
32296183
种属内
PLN P26678 DMPK Homo sapiens Q09013
Anti Tag CoIP
15598648
种属内
PLN P26678 CREB3L1 Homo sapiens Q96BA8
Validated Y2H
25910212
种属内
PLN P26678 CREB3L1 Homo sapiens Q96BA8
Y2H Array
25910212
种属内
PLN P26678 CREB3L1 Homo sapiens Q96BA8
Y2H Bait-Prey Pool
25910212
种属内
PLN P26678 SIT1 Homo sapiens Q9Y3P8
Y2H Prey Pooling
32296183
种属内
PLN P26678 SIT1 Homo sapiens Q9Y3P8
Validated Y2H
32296183
种属内
PLN P26678 SIT1 Homo sapiens Q9Y3P8
Y2H Array
32296183
种属内
PLN P26678 BIK Homo sapiens Q13323
Y2H Array
32296183
种属内
PLN P26678 BIK Homo sapiens Q13323
Y2H Prey Pooling
32296183
种属内
PLN P26678 BIK Homo sapiens Q13323
Validated Y2H
32296183
种属内
PLN P26678 STX1A Homo sapiens Q16623
Y2H Prey Pooling
32296183
种属内
PLN P26678 STX1A Homo sapiens Q16623
Validated Y2H
32296183
种属内
PLN P26678 STX1A Homo sapiens Q16623
Y2H Array
32296183
种属内
PLN P26678 MS4A7 Homo sapiens Q9GZW8
Y2H Prey Pooling
32296183
种属内
PLN P26678 MS4A7 Homo sapiens Q9GZW8
Validated Y2H
32296183
种属内
PLN P26678 MS4A7 Homo sapiens Q9GZW8
Y2H Array
32296183
种属内
PLN P26678 MGST3 Homo sapiens O14880
Y2H Array
32296183
种属内
PLN P26678 MGST3 Homo sapiens O14880
Y2H Prey Pooling
32296183
种属内
PLN P26678 FKBP8 Homo sapiens Q14318
Y2H Array
32296183
种属内
PLN P26678 FKBP8 Homo sapiens Q14318
Y2H Prey Pooling
32296183
种属内
PLN P26678 FKBP8 Homo sapiens Q14318
Validated Y2H
32296183
种属内
PLN P26678 CLDN7 Homo sapiens O95471
Y2H Prey Pooling
32296183
种属内
PLN P26678 BCL2L13 Homo sapiens Q9BXK5
Validated Y2H
32296183
种属内
PLN P26678 BCL2L13 Homo sapiens Q9BXK5
Y2H Prey Pooling
32296183
种属内
PLN P26678 BCL2L13 Homo sapiens Q9BXK5
Y2H Array
32296183
种属内
PLN P26678 BCL2L13 Homo sapiens Q9BXK5
Validated Y2H
25910212
种属内
PLN P26678 BCL2L13 Homo sapiens Q9BXK5
Y2H Bait-Prey Pool
25910212
种属内
PLN P26678 BCL2L13 Homo sapiens Q9BXK5
Y2H Array
25910212
种属内
PLN P26678 KIR2DL3 Homo sapiens P43628
Y2H Prey Pooling
32296183
种属内
PLN P26678 KIR2DL3 Homo sapiens P43628
Validated Y2H
32296183
种属内
PLN P26678 KIR2DL3 Homo sapiens P43628
Y2H Array
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

重组 PLN 蛋白

目录号 产品名 蛋白编号 纯度
HY-P72275 Cardiac phospholamban/PLN, Human (P.pastoris, GST) P26678 (M1-L52) ≥95%

PLN 抗体

目录号 产品名 应用 反应物种
HY-P81873 Phospho-Phospholamban (Ser16) Antibody (YA1618) WB Human, Mouse
HY-P81877 Phospholamban Antibody (YA1622) WB, IHC-P, IP Human, Mouse, Rat

关联疾病

疾病名称 别名
Cardiomyopathy, Dilated, 1p

Dilated Cardiomyopathy 1p

CMD1P

Cardiomyopathy, Dilated 1p

Cardiomyopathy, Dilated, Type 1p
Cardiomyopathy, Familial Hypertrophic, 18

Hypertrophic Cardiomyopathy 18

CMH18

Cardiomyopathy, Hypertrophic, 18

Cardiomyopathy Familial Hypertrophic 18

Cardiomyopathy, Familial Hypertrophic 18

Cardiomyopathy, Hypertrophic, Familial, Type 18
Arrhythmogenic Right Ventricular Dysplasia, Familial, 9

Arrhythmogenic Right Ventricular Dysplasia 9

ARVD9

Arrhythmogenic Right Ventricular Cardiomyopathy 9

Arvc9

Familial Arrhythmogenic Right Ventricular Dysplasia 9

Dysplasia, Arrhythmogenic Right Ventricular, Type 9
Dilated Cardiomyopathy

Familial Dilated Cardiomyopathy

Primary Dilated Cardiomyopathy

Idiopathic Dilated Cardiomyopathy

Congestive Cardiomyopathy

Idiopathic Dilation Cardiomyopathy

Primary Familial Dilated Cardiomyopathy

Cardiomyopathy, Dilated

DCM

Cardiomyopathy, Familial Dilated

Dilated Cardiomyopathy, Familial

Hypokinetic Dilated Cardiomyopathy, Familial

Familial Idiopathic Cardiomyopathy

Fdc

Cardiomyopathy, Familial Idiopathic

Idiopathic Cardiomegaly

Dilated Congestive Cardiomyopathy

Chronic Dilated Cardiomyopathy

Ccm - [Congestive Cardiomyopathy]

Cocm - [Congestive Cardiomyopathy]

Dcm - [Dilated Cardiomyopathy]

Dilated-Hypokinetic Cardiomyopathy

Congestive Idiopathic Cardiomyopathy

Primary Idiopathic Dilated Cardiomyopathy
Hypertrophic Cardiomyopathy

Hypertrophic Obstructive Cardiomyopathy

Cardiomyopathy, Hypertrophic

Cardiomyopathy Hypertrophic Obstructive

Cardiomyopathy, Hypertrophic, Familial

Idiopathic Myocardial Hypertrophy

Idiopathic Hypertrophic Cardiomyopathy

Obstructive Idiopathic Hypertrophic Cardiomyopathy

Obstructive Cardiomyopathy

Idiopathic Hypertrophic Subaortic Stenosis

Muscular Subaortic Stenosis

Hypertrophic Obstructive Subaortic Stenosis
Sudden Infant Death Syndrome

SIDS

Sudden Infant Death Syndrome, Susceptibility To

Cot Death

Crib Death

Sudden Death Of Nonspecific Cause In Infancy

Sudden Infant Death

Death, Sudden, Syndrome, Infant
Familial Isolated Dilated Cardiomyopathy

Familial Or Idiopathic Dilated Cardiomyopathy
Cardiac Arrest

Cardiopulmonary Arrest

Circulatory Arrest

Heart Arrest
Congestive Heart Failure

Congestive Heart Disease

Heart Failure

Cardiac Failure Congestive

Chf

Weak Heart

Heart Failure Congestive

Ccf - [Congestive Cardiac Failure]

Chf - [Congestive Heart Failure]

Congestive Cardiac Diseases

Congested Heart Failure

Congestive Cardiac Failure

Cardiac Anasarca

Cardiac Oedema

Cardiac Stasis

Cardiovascular Oedema

Cardiac Hydrops

Congestive Failure

Heart Congestion

Heart Fluid

Oedematous Heart
Brody Disease

Brody Myopathy

BROD

Sarcoplasmic Reticulum -Ca2+Atpase Deficiency

Myopathy, Brody
Schwartz-Jampel Syndrome, Type 1

Schwartz-Jampel Syndrome

SJS1

Schwartz-Jampel-Aberfeld Syndrome

Sjs

Chondrodystrophic Myotonia

Schwartz-Jampel Syndrome Type 1

Sja Syndrome

Aberfeld Syndrome

Burton Skeletal Dysplasia

Burton Syndrome

Catel-Hempel Syndrome

Myotonic Chondrodystrophy

Myotonic Myopathy, Dwarfism, Chondrodystrophy, Ocular And Facial Anomalies

Osteochondromuscular Dystrophy

Myotonic Myopathy, Dwarfism, Chondrodystrophy, And Ocular And Facial Abnormalities

Schwartz-Jampel Syndrome 1

Dysostosis Enchondralis Metaepiphysaria, Catel-Hempel Type

Catel-Hempel Type Dysostosis Enchondralis Metaepiphysaria

Schwartz Jampel Syndrome

Myotonic Myopathy Dwarfism Chondrodystrophy And Ocular And Facial Abnormalities

Schwartz Jampel Aberfeld Syndrome

Congenital Blepharophimosis, Myopia, Myopathy Syndrome

Kniest-Like Dysplasia With Pursed Lips And Ectopia Lentis
Arrhythmogenic Right Ventricular Cardiomyopathy

Arrhythmogenic Right Ventricular Dysplasia

Arvc

Arvd

Arrhythmogenic Right Ventricular Dysplasia/Cardiomyopathy

Arvc Cardiomyopathy

Arrhythmogenic Right Ventricular Cardiomyopathy-Dysplasia

Arvd/C

Right Ventricular Dysplasia, Arrhythmogenic

Ventricular Dysplasia, Right, Arrhythmogenic

Cardiomyopathy, Ventricular, Right, Arrhythmogenic

Dysplasia, Arrhythmogenic Right Ventricular
Brugada Syndrome

Sudden Unexpected Nocturnal Death Syndrome

Sudden Unexplained Nocturnal Death Syndrome

Bangungut

Brugada Type Idiopathic Ventricular Fibrillation

Pokkuri Death Syndrome

Sunds

Idiopathic Ventricular Fibrillation, Brugada Type

Sudden Unexplained Death

Dream Disease

Right Bundle Branch Block, St Segment Elevation, And Sudden Death Syndrome

Sudden Unexplained Death Syndrome

Suds

Sunds - [Sudden Unexplained Nocturnal Death Syndrome]
Periarthritis
Cantu Syndrome

Hypertrichotic Osteochondrodysplasia

Hypertrichotic Osteochondrodysplasia Cantu Type

Cantú Syndrome

Craniofaciocardioskeletal Syndrome

Hypertrichosis-Osteochondrodysplasia-Cardiomegaly Syndrome

Congenital Hypertrichosis-Acromegaloid Facial Features Spectrum

Congenital Hypertrichosis-Coarse Facial Features Spectrum

HTOCD

Osteochondrodysplasia, Hypertrichotic
Heart Disease

Heart Failure

Congenital Heart Disease

Heart Diseases

Congenital Heart Defects

Congenital Heart Defect

Heart Malformation

Congenital Anomaly Of Heart

Heart Defect

Heart-Congenital Defect

Congenital Heart Disorder

Heart Defects Congenital

Heart Defects, Congenital

Heart Defects

Heart Disease, Congenital

Disease, Heart, Congenital

Congestive Heart Failure
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-137561 Bexotegrast Inhibitor 99.67% 否
HY-47888 PLN-1474 Inhibitor 99.35% 否
HY-137561A Bexotegrast hydrochloride Inhibitor / 否
HY-RS10727 PLN Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus PLN RGD RGD:619894
Felis catus PLN VGNC VGNC:68906
Mus musculus PLN MGD MGI:97622
Canis familiaris PLN VGNC VGNC:44700
Bos taurus PLN VGNC VGNC:33038
Others PLN NCBI
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