2. Gene
  3. STK16 - serine/threonine kinase 16 Gene

STK16 - serine/threonine kinase 16 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：丝氨酸/苏氨酸激酶 16

种属: Homo sapiens

同用名: PSK; KRCT; MPSK; TSF1; hPSK; PKL12

基因 ID: 8576 | 基因类型: protein coding

关于 STK16

Cytogenetic location: 2q35 Genomic coordinates (GRCh38): 2:219,245,479-219,250,337 (from NCBI)

This gene has 13 transcripts (splice variants), 205 orthologues and 2 paralogues. Ubiquitous expression in thyroid (RPKM 7.6), brain (RPKM 6.9) and 25 other tissues.

功能概要

预测启用蛋白质丝氨酸/苏氨酸激酶活性。参与蛋白质自身磷酸化。位于胞质溶胶中；核质；和质膜。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable protein serine/threonine kinase activity. Involved in protein autophosphorylation. Located in cytosol; nucleoplasm; and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

STK16 基因产物(4)

mRNA Protein Name
NM_001008910.4 NP_001008910.1 serine/threonine-protein kinase 16 isoform 1
NM_001330213.2 NP_001317142.1 serine/threonine-protein kinase 16 isoform 1
NM_001330214.1 NP_001317143.1 serine/threonine-protein kinase 16 isoform 2
NM_001330215.2 NP_001317144.1 serine/threonine-protein kinase 16 isoform 3
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
16189514 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in protein autophosphorylation IDA
IDA: 通过直接分析推断
18184589 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

STK16 蛋白结构

Pkinase

Pkinase: Protein kinase domain (22 - 287)

  • 0
  • 100
  • 200
  • 305 a.a.
蛋白主名 其他名称

serine/threonine-protein kinase 16

TGF-beta-stimulated factor 1

STK16 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
STK16 O75716 KRTAP10-8 Homo sapiens P60410
Validated Y2H
25416956
种属内
STK16 O75716 KRTAP10-8 Homo sapiens P60410
Y2H Prey Pooling
32296183
种属内
STK16 O75716 KRTAP10-8 Homo sapiens P60410
Validated Y2H
32296183
种属内
STK16 O75716 KRTAP10-8 Homo sapiens P60410
Y2H Array
25416956
种属内
STK16 O75716 KRTAP10-8 Homo sapiens P60410
Y2H Array
32296183
种属内
STK16 O75716 KRTAP10-9 Homo sapiens P60411
Validated Y2H
25416956
种属内
STK16 O75716 KRTAP10-5 Homo sapiens P60370
Y2H Array
25416956
种属内
STK16 O75716 KRTAP10-7 Homo sapiens P60409
Y2H Prey Pooling
25416956
种属内
STK16 O75716 ADAMTSL4 Homo sapiens Q6UY14-3
Y2H Prey Pooling
32296183
种属内
STK16 O75716 ADAMTSL4 Homo sapiens Q6UY14-3
Validated Y2H
32296183
种属内
STK16 O75716 ADAMTSL4 Homo sapiens Q6UY14-3
Y2H Array
32296183
种属内
STK16 O75716 KCTD14 Homo sapiens Q9BQ13
Validated Y2H
25416956
种属内
STK16 O75716 KCTD14 Homo sapiens Q9BQ13
Y2H Array
25416956
种属内
STK16 O75716 KCTD14 Homo sapiens Q9BQ13
Y2H Array
29892012
种属内
STK16 O75716 ZNF774 Homo sapiens Q6NX45
Validated Y2H
32296183
种属内
STK16 O75716 ZNF774 Homo sapiens Q6NX45
Y2H Array
32296183
种属内
STK16 O75716 ZNF774 Homo sapiens Q6NX45
Y2H Prey Pooling
32296183
种属内
STK16 O75716 ZNF343 Homo sapiens Q6P1L6
Y2H Prey Pooling
32296183
种属内
STK16 O75716 ZNF343 Homo sapiens Q6P1L6
Y2H Array
32296183
种属内
STK16 O75716 ZNF343 Homo sapiens Q6P1L6
Validated Y2H
32296183
种属内
STK16 O75716 KRTAP11-1 Homo sapiens Q8IUC1
Y2H Array
32296183
种属内
STK16 O75716 KRTAP11-1 Homo sapiens Q8IUC1
Validated Y2H
32296183
种属内
STK16 O75716 KRTAP11-1 Homo sapiens Q8IUC1
Y2H Prey Pooling
32296183
种属内
STK16 O75716 KLHL20 Homo sapiens Q9BS75
Validated Y2H
32296183
种属内
STK16 O75716 KLHL20 Homo sapiens Q9BS75
Y2H Prey Pooling
32296183
种属内
STK16 O75716 KLHL20 Homo sapiens Q9BS75
Y2H Array
32296183
种属内
STK16 O75716 REL Homo sapiens Q04864-2
Y2H Array
32296183
种属内
STK16 O75716 REL Homo sapiens Q04864-2
Y2H Prey Pooling
32296183
种属内
STK16 O75716 REL Homo sapiens Q04864-2
Validated Y2H
32296183
种属内
STK16 O75716 KPRP Homo sapiens Q5T749
Y2H Prey Pooling
32296183
种属内
STK16 O75716 KPRP Homo sapiens Q5T749
Y2H Array
32296183
种属内
STK16 O75716 KPRP Homo sapiens Q5T749
Validated Y2H
32296183
种属内
STK16 O75716 FXR1 Homo sapiens P51114-2
Y2H Prey Pooling
32296183
种属内
STK16 O75716 FXR1 Homo sapiens P51114-2
Y2H Array
32296183
种属内
STK16 O75716 FXR1 Homo sapiens P51114-2
Validated Y2H
32296183
种属内
STK16 O75716 PRDM6 Homo sapiens Q9NQX0
Y2H Prey Pooling
32296183
种属内
STK16 O75716 PRDM6 Homo sapiens Q9NQX0
Validated Y2H
32296183
种属内
STK16 O75716 PRDM6 Homo sapiens Q9NQX0
Y2H Array
32296183
种属内
STK16 O75716 KRTAP1-3 Homo sapiens Q8IUG1
Y2H Array
32296183
种属内
STK16 O75716 KRTAP1-3 Homo sapiens Q8IUG1
Y2H Prey Pooling
32296183
种属内
STK16 O75716 KRTAP13-2 Homo sapiens Q52LG2
Y2H Array
32296183
种属内
STK16 O75716 KRTAP13-2 Homo sapiens Q52LG2
Validated Y2H
32296183
种属内
STK16 O75716 KRTAP13-2 Homo sapiens Q52LG2
Y2H Prey Pooling
32296183
种属内
STK16 O75716 KRTAP1-1 Homo sapiens Q07627
Validated Y2H
32296183
种属内
STK16 O75716 KRTAP1-1 Homo sapiens Q07627
Y2H Array
32296183
种属内
STK16 O75716 KRTAP1-1 Homo sapiens Q07627
Y2H Prey Pooling
32296183
种属内
STK16 O75716 USP54 Homo sapiens Q70EL1-9
Validated Y2H
32296183
种属内
STK16 O75716 USP54 Homo sapiens Q70EL1-9
Y2H Array
32296183
种属内
STK16 O75716 USP54 Homo sapiens Q70EL1-9
Y2H Prey Pooling
32296183
种属内
STK16 O75716 NAA80 Homo sapiens Q93015-2
Validated Y2H
32296183
种属内
STK16 O75716 MIER3 Homo sapiens Q7Z3K6-2
Y2H Prey Pooling
32296183
种属内
STK16 O75716 MIER3 Homo sapiens Q7Z3K6-2
Validated Y2H
32296183
种属内
STK16 O75716 MIER3 Homo sapiens Q7Z3K6-2
Y2H Array
32296183
种属内
STK16 O75716 KCTD14 Homo sapiens Q9BQ13-2
Y2H Prey Pooling
32296183
种属内
STK16 O75716 KCTD14 Homo sapiens Q9BQ13-2
Validated Y2H
32296183
种属内
STK16 O75716 KCTD14 Homo sapiens Q9BQ13-2
Y2H Array
32296183
种属内
STK16 O75716 ATP23 Homo sapiens Q9Y6H3
Y2H Prey Pooling
32296183
种属内
STK16 O75716 ATP23 Homo sapiens Q9Y6H3
Validated Y2H
32296183
种属内
STK16 O75716 ATP23 Homo sapiens Q9Y6H3
Y2H Array
32296183
种属内
STK16 O75716 RSPO4 Homo sapiens Q2I0M5
Validated Y2H
32296183
种属内
STK16 O75716 RSPO4 Homo sapiens Q2I0M5
Y2H Prey Pooling
32296183
种属内
STK16 O75716 RSPO4 Homo sapiens Q2I0M5
Y2H Array
32296183
种属内
STK16 O75716 BHLHA9 Homo sapiens Q7RTU4
Y2H Prey Pooling
32296183
种属内
STK16 O75716 BHLHA9 Homo sapiens Q7RTU4
Validated Y2H
32296183
种属内
STK16 O75716 BHLHA9 Homo sapiens Q7RTU4
Y2H Array
32296183
种属内
STK16 O75716 NOTCH2NLC Homo sapiens P0DPK4
Y2H Prey Pooling
32296183
种属内
STK16 O75716 NOTCH2NLC Homo sapiens P0DPK4
Validated Y2H
32296183
种属内
STK16 O75716 NOTCH2NLC Homo sapiens P0DPK4
Y2H Array
32296183
种属内
STK16 O75716 KRTAP6-3 Homo sapiens Q3LI67
Y2H Array
32296183
种属内
STK16 O75716 KRTAP6-3 Homo sapiens Q3LI67
Y2H Prey Pooling
32296183
种属内
STK16 O75716 EFHC2 Homo sapiens Q5JST6
Y2H Array
25416956
种属内
STK16 O75716 TNFAIP1 Homo sapiens Q13829
Y2H Prey Pooling
25416956
种属内
STK16 O75716 TNFAIP1 Homo sapiens Q13829
Y2H Array
25416956
种属内
STK16 O75716 PKNOX2 Homo sapiens Q96KN3
Y2H Prey Pooling
32296183
种属内
STK16 O75716 PKNOX2 Homo sapiens Q96KN3
Validated Y2H
32296183
种属内
STK16 O75716 PKNOX2 Homo sapiens Q96KN3
Y2H Array
32296183
种属内
STK16 O75716 MIIP Homo sapiens Q5JXC2
Y2H Array
31515488
种属内
STK16 O75716 MIIP Homo sapiens Q5JXC2
Validated Y2H
25416956
种属内
STK16 O75716 MIIP Homo sapiens Q5JXC2
Y2H Array
25416956
种属内
STK16 O75716 PRKAR1B Homo sapiens P31321
Validated Y2H
32296183
种属内
STK16 O75716 PRKAR1B Homo sapiens P31321
Y2H Array
32296183
种属内
STK16 O75716 PRKAR1B Homo sapiens P31321
Y2H Prey Pooling
32296183
种属内
STK16 O75716 PTH1R Homo sapiens Q03431
Y2H Array
32296183
种属内
STK16 O75716 PTH1R Homo sapiens Q03431
Y2H Prey Pooling
32296183
种属内
STK16 O75716 PTH1R Homo sapiens Q03431
Validated Y2H
32296183
种属内
STK16 O75716 SKIL Homo sapiens P12757
Y2H Prey Pooling
25416956
种属内
STK16 O75716 SKIL Homo sapiens P12757
Validated Y2H
25416956
种属内
STK16 O75716 REL Homo sapiens Q04864
Y2H Prey Pooling
25416956
种属内
STK16 O75716 REL Homo sapiens Q04864
Validated Y2H
25416956
种属内
STK16 O75716 ZNF330 Homo sapiens Q9Y3S2
Y2H Array
32296183
种属内
STK16 O75716 ZNF330 Homo sapiens Q9Y3S2
Y2H Prey Pooling
32296183
种属内
STK16 O75716 ZNF330 Homo sapiens Q9Y3S2
Validated Y2H
32296183
种属内
STK16 O75716 CYSRT1 Homo sapiens A8MQ03
Y2H Prey Pooling
32296183
种属内
STK16 O75716 CYSRT1 Homo sapiens A8MQ03
Y2H Array
32296183
种属内
STK16 O75716 DNAJA3 Homo sapiens Q96EY1-2
Y2H Prey Pooling
25416956
种属内
STK16 O75716 SAXO1 Homo sapiens Q8IYX7
Validated Y2H
32296183
种属内
STK16 O75716 SAXO1 Homo sapiens Q8IYX7
Y2H Array
32296183
种属内
STK16 O75716 SAXO1 Homo sapiens Q8IYX7
Y2H Prey Pooling
32296183
种属内
STK16 O75716 TRIM42 Homo sapiens Q8IWZ5
Validated Y2H
32296183
种属内
STK16 O75716 TRIM42 Homo sapiens Q8IWZ5
Y2H Array
32296183
种属内
STK16 O75716 TRIM42 Homo sapiens Q8IWZ5
Y2H Prey Pooling
32296183
种属内
STK16 O75716 SOCS2 Homo sapiens O14508
Y2H Prey Pooling
32296183
种属内
STK16 O75716 SOCS2 Homo sapiens O14508
Y2H Array
32296183
种属内
STK16 O75716 GABPA Homo sapiens Q06546
Validated Y2H
32296183
种属间
STK16 O75716 tir Escherichia coli O157:H7 Q7DB77
Lumier
25519916
种属内
STK16 O75716 INCA1 Homo sapiens Q0VD86
Y2H Prey Pooling
32296183
种属内
STK16 O75716 INCA1 Homo sapiens Q0VD86
Validated Y2H
25416956
种属内
STK16 O75716 INCA1 Homo sapiens Q0VD86
Validated Y2H
32296183
种属内
STK16 O75716 INCA1 Homo sapiens Q0VD86
Y2H Array
25416956
种属内
STK16 O75716 INCA1 Homo sapiens Q0VD86
Y2H Array
32296183
种属内
STK16 O75716 AGR2 Homo sapiens O95994
Validated Y2H
32296183
种属内
STK16 O75716 AGR2 Homo sapiens O95994
Y2H Array
32296183
种属内
STK16 O75716 AGR2 Homo sapiens O95994
Y2H Prey Pooling
32296183
种属内
STK16 O75716 TLE5 Homo sapiens Q08117
Y2H Prey Pooling
25416956
种属内
STK16 O75716 TLE5 Homo sapiens Q08117
Validated Y2H
25416956
种属内
STK16 O75716 TRIM27 Homo sapiens P14373
Validated Y2H
25416956
种属内
STK16 O75716 TRIM27 Homo sapiens P14373
Y2H Prey Pooling
25416956
种属内
STK16 O75716 DRG1 Homo sapiens Q9Y295
Y2H Array
25416956
种属内
STK16 O75716 DRG1 Homo sapiens Q9Y295
Validated Y2H
25416956
种属内
STK16 O75716 TCF12 Homo sapiens Q99081
Validated Y2H
25416956
种属内
STK16 O75716 FRS3 Homo sapiens O43559
Y2H Array
32296183
种属内
STK16 O75716 FRS3 Homo sapiens O43559
Y2H Prey Pooling
32296183
种属内
STK16 O75716 PLA2G10 Homo sapiens O15496
Y2H Array
32296183
种属内
STK16 O75716 PLA2G10 Homo sapiens O15496
Y2H Prey Pooling
32296183
种属内
STK16 O75716 CALCOCO2 Homo sapiens Q13137
Y2H Prey Pooling
25416956
种属内
STK16 O75716 CALCOCO2 Homo sapiens Q13137
Validated Y2H
25416956
种属内
STK16 O75716 PLSCR1 Homo sapiens O15162
Y2H Prey Pooling
25416956
种属内
STK16 O75716 ADAMTSL4 Homo sapiens Q6UY14
Y2H Array
19060904
种属内
STK16 O75716 ADAMTSL4 Homo sapiens Q6UY14
Y2H Pooling
19060904
种属内
STK16 O75716 ADAMTSL4 Homo sapiens Q6UY14
Y2H Pooling
16189514
种属内
STK16 O75716 DDIT4L Homo sapiens Q96D03
Y2H Prey Pooling
32296183
种属内
STK16 O75716 DDIT4L Homo sapiens Q96D03
Validated Y2H
32296183
种属内
STK16 O75716 DDIT4L Homo sapiens Q96D03
Y2H Array
32296183
种属内
STK16 O75716 TRIP6 Homo sapiens Q15654
Y2H Prey Pooling
25416956
种属内
STK16 O75716 SPRY2 Homo sapiens O43597
Y2H Prey Pooling
25416956
种属内
STK16 O75716 MTUS2 Homo sapiens Q5JR59
Y2H Array
25416956
种属内
STK16 O75716 MTUS2 Homo sapiens Q5JR59
Y2H Prey Pooling
25416956
种属内
STK16 O75716 EFEMP2 Homo sapiens O95967
Validated Y2H
32296183
种属内
STK16 O75716 EFEMP2 Homo sapiens O95967
Y2H Prey Pooling
32296183
种属内
STK16 O75716 EFEMP2 Homo sapiens O95967
Y2H Array
32296183
种属内
STK16 O75716 EFEMP2 Homo sapiens O95967
Y2H Array
25416956
种属内
STK16 O75716 KCTD17 Homo sapiens Q8N5Z5
Y2H Prey Pooling
25416956
种属内
STK16 O75716 KCTD17 Homo sapiens Q8N5Z5
Y2H Prey Pooling
32296183
种属内
STK16 O75716 KCTD17 Homo sapiens Q8N5Z5
Validated Y2H
32296183
种属内
STK16 O75716 KCTD17 Homo sapiens Q8N5Z5
Y2H Array
32296183
种属内
STK16 O75716 KCTD17 Homo sapiens Q8N5Z5
Y2H Pooling
16189514
种属内
STK16 O75716 RPIA Homo sapiens P49247
Validated Y2H
25416956
种属内
STK16 O75716 RPIA Homo sapiens P49247
Y2H Pooling
16189514
种属内
STK16 O75716 RFX6 Homo sapiens Q8HWS3
Validated Y2H
25416956
种属内
STK16 O75716 RFX6 Homo sapiens Q8HWS3
Y2H Array
25416956
种属内
STK16 O75716 IKZF3 Homo sapiens Q9UKT9
Y2H Array
25416956
种属内
STK16 O75716 IKZF3 Homo sapiens Q9UKT9
Validated Y2H
25416956
种属内
STK16 O75716 CRX Homo sapiens O43186
Y2H Array
25416956
种属内
STK16 O75716 CRX Homo sapiens O43186
Y2H Prey Pooling
25416956
种属内
STK16 O75716 MEOX2 Homo sapiens P50222
Y2H Prey Pooling
25416956
种属内
STK16 O75716 MEOX2 Homo sapiens P50222
Y2H Array
25416956
种属内
STK16 O75716 PLSCR3 Homo sapiens Q9NRY6
Y2H Prey Pooling
25416956
种属内
STK16 O75716 PLSCR3 Homo sapiens Q9NRY6
Validated Y2H
25416956
种属内
STK16 O75716 PLSCR3 Homo sapiens Q9NRY6
Y2H Prey Pooling
32296183
种属内
STK16 O75716 PLSCR3 Homo sapiens Q9NRY6
Validated Y2H
32296183
种属内
STK16 O75716 PLSCR3 Homo sapiens Q9NRY6
Y2H Array
32296183
种属内
STK16 O75716 PCSK5 Homo sapiens Q92824
Y2H Prey Pooling
25416956
种属内
STK16 O75716 ARNT2 Homo sapiens Q9HBZ2
Y2H Prey Pooling
32296183
种属内
STK16 O75716 ARNT2 Homo sapiens Q9HBZ2
Y2H Array
32296183
种属内
STK16 O75716 CBX3 Homo sapiens Q13185
Y2H Prey Pooling
32296183
种属内
STK16 O75716 CBX3 Homo sapiens Q13185
Validated Y2H
32296183
种属内
STK16 O75716 CBX3 Homo sapiens Q13185
Y2H Array
32296183
种属间
STK16 O75716 Drg1 Mus musculus P32233
Y2H
18184589
种属间
STK16 O75716 Drg1 Mus musculus P32233
Pull Down
18184589
种属间
STK16 O75716 Drg1 Mus musculus P32233
Protein Kinase Assay
18184589
种属间
STK16 O75716 Drg1 Mus musculus P32233
Anti Bait CoIP
18184589
种属内
STK16 O75716 CFP Homo sapiens P27918
Y2H Array
32296183
种属内
STK16 O75716 CFP Homo sapiens P27918
Y2H Prey Pooling
32296183
种属内
STK16 O75716 CFP Homo sapiens P27918
Validated Y2H
32296183
种属内
STK16 O75716 NOTCH2NLA Homo sapiens Q7Z3S9
Validated Y2H
25416956
种属内
STK16 O75716 KRT31 Homo sapiens Q15323
Y2H Prey Pooling
32296183
种属内
STK16 O75716 KRT31 Homo sapiens Q15323
Validated Y2H
32296183
种属内
STK16 O75716 KRT31 Homo sapiens Q15323
Y2H Array
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

重组 STK16 蛋白

目录号 产品名 蛋白编号 纯度
HY-P76097 STK16 Protein, Human (His) O75716 (M1-I305) ≥95%

关联疾病

疾病名称 别名
Diffuse Mesangial Sclerosis

Familial Mesangial Sclerosis

Mesangial Sclerosis, Diffuse

Dms

Diffuse Isolated Mesangial Sclerosis

Isolated Diffuse Mesangial Sclerosis

Nephrotic Syndrome, Early Onset With Diffuse Mesangial Sclerosis
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-19353 SR7826 Inhibitor 99.30% 否
HY-101270 STK16-IN-1 Inhibitor 99.95% 否
HY-RS13923 STK16 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Felis catus STK16 VGNC VGNC:65776
Mus musculus STK16 MGD MGI:1313271
Rattus norvegicus STK16 RGD RGD:629474
Canis familiaris STK16 VGNC VGNC:46906
Bos taurus STK16 VGNC VGNC:35387
Macaca mulatta STK16 VGNC VGNC:77912
Others STK16 NCBI
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