DR1 - down-regulator of transcription 1 Gene

中文名称：转录下调因子 1

种属: Homo sapiens

同用名: NC2; NC2B; NCB2; NC2-BETA

基因 ID: 1810 | 基因类型: protein coding

关于 DR1

Cytogenetic location: 1p22.1 Genomic coordinates (GRCh38): 1:93,345,907-93,369,493 (from NCBI)

This gene has 3 transcripts (splice variants), 214 orthologues and 2 paralogues. Ubiquitous expression in testis (RPKM 31.0), lymph node (RPKM 21.9) and 25 other tissues.

功能概要

该基因编码一种 TBP- (TATA 盒结合蛋白) 相关的磷蛋白，可抑制基础和激活的转录水平。编码的蛋白质在体内被磷酸化，这种磷酸化影响其与 TBP 的相互作用。该蛋白质在氨基末端包含一个组蛋白折叠基序、一个 TBP 结合域以及一个富含谷氨酰胺和丙氨酸的区域。 DR1 阻遏物复合物与 TBP 启动子复合物的结合可能建立了一种机制，其中改变的 DNA 构象以及更高阶复合物的形成抑制了预起始复合物的组装并控制了 RNA 聚合酶 II 转录的速率。[RefSeq 提供，2008 年 7 月]

This gene encodes a TBP- (TATA box-binding protein) associated phosphoprotein that represses both basal and activated levels of transcription. The encoded protein is phosphorylated in vivo and this phosphorylation affects its interaction with TBP. This protein contains a histone fold motif at the amino terminus, a TBP-binding domain, and a glutamine- and alanine-rich region. The binding of DR1 repressor complexes to TBP-promoter complexes may establish a mechanism in which an altered DNA conformation, together with the formation of higher order complexes, inhibits the assembly of the preinitiation complex and controls the rate of RNA polymerase II transcription. [provided by RefSeq, Jul 2008]

DR1 基因产物(1)

mRNA	Protein	Name
NM_001938.3	NP_001929.1	protein Dr1

基因本体论

分子功能
生物过程
细胞组分

分子功能 GO 注释	逻辑证据	参考文献	来源
enables RNA polymerase II general transcription initiation factor activity	IDA IDA: 通过直接分析推断	8670811	GOA
enables TBP-class protein binding	IDA IDA: 通过直接分析推断	18838386	GOA
enables TBP-class protein binding	IPI IPI: 通过物理相互作用推断	8670811	GOA
enables protein binding	IPI IPI: 通过物理相互作用推断	8670811	GOA

生物过程 GO 注释	逻辑证据	参考文献	来源
involved in negative regulation of transcription by RNA polymerase II	IDA IDA: 通过直接分析推断	8670811	GOA
involved in regulation of DNA-templated transcription	IMP IMP: 通过突变表型推断	19936620	GOA
involved in regulation of cell cycle	IMP IMP: 通过突变表型推断	19103755	GOA
involved in regulation of cell division	IDA IDA: 通过直接分析推断	20562830	GOA
involved in regulation of transcription by RNA polymerase II	IDA IDA: 通过直接分析推断	22055187	GOA
involved in regulation of tubulin deacetylation	IMP IMP: 通过突变表型推断	20562830	GOA

细胞组分 GO 注释	逻辑证据	参考文献	来源
part of ATAC complex	IDA IDA: 通过直接分析推断	18838386	GOA
part of RNA polymerase II transcription regulator complex	IDA IDA: 通过直接分析推断	8670811	GOA

EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

DR1 蛋白结构

CBFD_NFYB_HMF

0
100
176 a.a.

蛋白主名

其他名称

protein Dr1

TATA-binding protein-associated phosphoprotein

DR1 蛋白互作信息

分类	蛋白名称	蛋白编号	互作蛋白	互作蛋白种属	互作蛋白编号	实验方法	参考文献
Intra	DR1	Q01658	ZSCAN22	Homo sapiens	P10073	Validated Y2H	32814053
Intra	DR1	Q01658	ZSCAN22	Homo sapiens	P10073	Y2H Array	32814053
Intra	DR1	Q01658	ZSCAN22	Homo sapiens	P10073	Y2H Pooling	32814053
Intra	DR1	Q01658	TBP	Homo sapiens	Q32MN6	Validated Y2H	32296183
Intra	DR1	Q01658	ASCL4	Homo sapiens	Q6XD76	Y2H Array	32814053
Intra	DR1	Q01658	ASCL4	Homo sapiens	Q6XD76	Y2H Pooling	32814053
Intra	DR1	Q01658	ASCL4	Homo sapiens	Q6XD76	Validated Y2H	32814053
Intra	DR1	Q01658	JADE3	Homo sapiens	Q92613	Validated Y2H	32814053
Intra	DR1	Q01658	JADE3	Homo sapiens	Q92613	Y2H Array	32814053
Intra	DR1	Q01658	JADE3	Homo sapiens	Q92613	Y2H Pooling	32814053
Intra	DR1	Q01658	PBX4	Homo sapiens	Q9BYU1	Y2H Array	32814053
Intra	DR1	Q01658	PBX4	Homo sapiens	Q9BYU1	Y2H Pooling	32814053
Intra	DR1	Q01658	PBX4	Homo sapiens	Q9BYU1	Validated Y2H	32814053
Intra	DR1	Q01658	q9h669_human	Homo sapiens	Q9H669	Validated Y2H	32814053
Intra	DR1	Q01658	q9h669_human	Homo sapiens	Q9H669	Y2H Array	32814053
Intra	DR1	Q01658	q9h669_human	Homo sapiens	Q9H669	Y2H Pooling	32814053
Intra	DR1	Q01658	LARP4B	Homo sapiens	Q92615	Y2H Pooling	32814053
Intra	DR1	Q01658	LARP4B	Homo sapiens	Q92615	Validated Y2H	32814053
Intra	DR1	Q01658	LARP4B	Homo sapiens	Q92615	Y2H Array	32814053
Intra	DR1	Q01658	MAGEC3	Homo sapiens	Q8TD91-2	Y2H Pooling	32814053
Intra	DR1	Q01658	MAGEC3	Homo sapiens	Q8TD91-2	Validated Y2H	32814053
Intra	DR1	Q01658	MAGEC3	Homo sapiens	Q8TD91-2	Y2H Array	32814053
Intra	DR1	Q01658	USP2	Homo sapiens	O75604-3	Y2H Pooling	32814053
Intra	DR1	Q01658	USP2	Homo sapiens	O75604-3	Validated Y2H	32814053
Intra	DR1	Q01658	USP2	Homo sapiens	O75604-3	Y2H Array	32814053
Intra	DR1	Q01658	C14orf93	Homo sapiens	Q9H972-2	Validated Y2H	32814053
Intra	DR1	Q01658	C14orf93	Homo sapiens	Q9H972-2	Y2H Pooling	32814053
Intra	DR1	Q01658	C14orf93	Homo sapiens	Q9H972-2	Y2H Array	32814053
Intra	DR1	Q01658	EMILIN1	Homo sapiens	Q9Y6C2-2	Y2H Array	32814053
Intra	DR1	Q01658	EMILIN1	Homo sapiens	Q9Y6C2-2	Y2H Pooling	32814053
Intra	DR1	Q01658	EMILIN1	Homo sapiens	Q9Y6C2-2	Validated Y2H	32814053
Intra	DR1	Q01658	CFAP100	Homo sapiens	Q494V2-2	Validated Y2H	32814053
Intra	DR1	Q01658	CFAP100	Homo sapiens	Q494V2-2	Y2H Array	32814053
Intra	DR1	Q01658	CFAP100	Homo sapiens	Q494V2-2	Y2H Pooling	32814053
Intra	DR1	Q01658	NFYC	Homo sapiens	Q13952-2	Validated Y2H	32296183
Intra	DR1	Q01658	ZC2HC1C	Homo sapiens	Q53FD0-2	Validated Y2H	32814053
Intra	DR1	Q01658	ZC2HC1C	Homo sapiens	Q53FD0-2	Y2H Array	32814053
Intra	DR1	Q01658	ZC2HC1C	Homo sapiens	Q53FD0-2	Y2H Pooling	32814053
Intra	DR1	Q01658	PRMT1	Homo sapiens	Q99873-2	Y2H Pooling	32814053
Intra	DR1	Q01658	PRMT1	Homo sapiens	Q99873-2	Validated Y2H	32814053
Intra	DR1	Q01658	PRMT1	Homo sapiens	Q99873-2	Y2H Array	32814053
Intra	DR1	Q01658	ZNF829	Homo sapiens	Q3KNS6-3	Y2H Pooling	32814053
Intra	DR1	Q01658	ZNF829	Homo sapiens	Q3KNS6-3	Validated Y2H	32814053
Intra	DR1	Q01658	ZNF829	Homo sapiens	Q3KNS6-3	Y2H Array	32814053
Intra	DR1	Q01658	NVL	Homo sapiens	O15381-5	Validated Y2H	32814053
Intra	DR1	Q01658	NVL	Homo sapiens	O15381-5	Y2H Array	32814053
Intra	DR1	Q01658	NVL	Homo sapiens	O15381-5	Y2H Pooling	32814053
Intra	DR1	Q01658	DPP9	Homo sapiens	Q86TI2-2	Validated Y2H	32814053
Intra	DR1	Q01658	DPP9	Homo sapiens	Q86TI2-2	Y2H Array	32814053
Intra	DR1	Q01658	DPP9	Homo sapiens	Q86TI2-2	Y2H Pooling	32814053
Intra	DR1	Q01658	GOLGA2P5	Homo sapiens	Q9HBQ8	Validated Y2H	32814053
Intra	DR1	Q01658	GOLGA2P5	Homo sapiens	Q9HBQ8	Y2H Array	32814053
Intra	DR1	Q01658	GOLGA2P5	Homo sapiens	Q9HBQ8	Y2H Pooling	32814053
Intra	DR1	Q01658	PHF19	Homo sapiens	Q5T6S3	Validated Y2H	32814053
Intra	DR1	Q01658	PHF19	Homo sapiens	Q5T6S3	Y2H Pooling	32814053
Intra	DR1	Q01658	PHF19	Homo sapiens	Q5T6S3	Y2H Array	32814053
Intra	DR1	Q01658	RNF34	Homo sapiens	Q969K3	Y2H Pooling	32814053
Intra	DR1	Q01658	RNF34	Homo sapiens	Q969K3	Validated Y2H	32814053
Intra	DR1	Q01658	RNF34	Homo sapiens	Q969K3	Y2H Array	32814053
Intra	DR1	Q01658	DPF1	Homo sapiens	Q92782-2	Validated Y2H	32814053
Intra	DR1	Q01658	DPF1	Homo sapiens	Q92782-2	Y2H Array	32814053
Intra	DR1	Q01658	DPF1	Homo sapiens	Q92782-2	Y2H Pooling	32814053
Intra	DR1	Q01658	ANXA8	Homo sapiens	P13928	Validated Y2H	32814053
Intra	DR1	Q01658	ANXA8	Homo sapiens	P13928	Y2H Pooling	32814053
Intra	DR1	Q01658	ANXA8	Homo sapiens	P13928	Y2H Array	32814053
Intra	DR1	Q01658	ZNF488	Homo sapiens	Q96MN9-2	Validated Y2H	32814053
Intra	DR1	Q01658	ZNF488	Homo sapiens	Q96MN9-2	Y2H Pooling	32814053
Intra	DR1	Q01658	ZNF488	Homo sapiens	Q96MN9-2	Y2H Array	32814053
Intra	DR1	Q01658	HES4	Homo sapiens	Q9HCC6	Validated Y2H	32814053
Intra	DR1	Q01658	HES4	Homo sapiens	Q9HCC6	Y2H Array	32814053
Intra	DR1	Q01658	HES4	Homo sapiens	Q9HCC6	Y2H Pooling	32814053
Intra	DR1	Q01658	KLF15	Homo sapiens	Q9UIH9	Validated Y2H	32814053
Intra	DR1	Q01658	KLF15	Homo sapiens	Q9UIH9	Y2H Pooling	32814053
Intra	DR1	Q01658	KLF15	Homo sapiens	Q9UIH9	Y2H Array	32814053
Intra	DR1	Q01658	GPSM3	Homo sapiens	Q9Y4H4	Y2H Array	32814053
Intra	DR1	Q01658	GPSM3	Homo sapiens	Q9Y4H4	Y2H Pooling	32814053
Intra	DR1	Q01658	GPSM3	Homo sapiens	Q9Y4H4	Validated Y2H	32814053
Intra	DR1	Q01658	RPS4X	Homo sapiens	P62701	Validated Y2H	32814053
Intra	DR1	Q01658	RPS4X	Homo sapiens	P62701	Y2H Pooling	32814053
Intra	DR1	Q01658	RPS4X	Homo sapiens	P62701	Y2H Array	32814053
Intra	DR1	Q01658	RPP25	Homo sapiens	Q9BUL9	Y2H Array	32814053
Intra	DR1	Q01658	RPP25	Homo sapiens	Q9BUL9	Y2H Pooling	32814053
Intra	DR1	Q01658	RPP25	Homo sapiens	Q9BUL9	Validated Y2H	32814053
Intra	DR1	Q01658	FAM117B	Homo sapiens	Q6P1L5	Validated Y2H	32814053
Intra	DR1	Q01658	FAM117B	Homo sapiens	Q6P1L5	Y2H Array	32814053
Intra	DR1	Q01658	FAM117B	Homo sapiens	Q6P1L5	Y2H Pooling	32814053
Intra	DR1	Q01658	MYC	Homo sapiens	P01106	Validated Y2H	32814053
Intra	DR1	Q01658	MYC	Homo sapiens	P01106	Y2H Array	32814053
Intra	DR1	Q01658	MYC	Homo sapiens	P01106	Y2H Pooling	32814053
Intra	DR1	Q01658	LPIN1	Homo sapiens	Q14693	Y2H Pooling	32814053
Intra	DR1	Q01658	LPIN1	Homo sapiens	Q14693	Validated Y2H	32814053
Intra	DR1	Q01658	LPIN1	Homo sapiens	Q14693	Y2H Array	32814053
Intra	DR1	Q01658	FAM98C	Homo sapiens	Q17RN3	Y2H Array	32814053
Intra	DR1	Q01658	FAM98C	Homo sapiens	Q17RN3	Y2H Pooling	32814053
Intra	DR1	Q01658	FAM98C	Homo sapiens	Q17RN3	Validated Y2H	32814053
Intra	DR1	Q01658	SAP30	Homo sapiens	O75446	Y2H Pooling	32814053
Intra	DR1	Q01658	SAP30	Homo sapiens	O75446	Validated Y2H	32814053
Intra	DR1	Q01658	SAP30	Homo sapiens	O75446	Y2H Array	32814053
Intra	DR1	Q01658	VSX2	Homo sapiens	P58304	Validated Y2H	32814053
Intra	DR1	Q01658	VSX2	Homo sapiens	P58304	Y2H Pooling	32814053
Intra	DR1	Q01658	VSX2	Homo sapiens	P58304	Y2H Array	32814053
Intra	DR1	Q01658	DRAP1	Homo sapiens	Q14919	SLC	31467278
Intra	DR1	Q01658	DRAP1	Homo sapiens	Q14919	BRET	29997244
Intra	DR1	Q01658	DRAP1	Homo sapiens	Q14919	Y2H Pooling	18692475
Intra	DR1	Q01658	DRAP1	Homo sapiens	Q14919	Lumier	29997244
Intra	DR1	Q01658	DRAP1	Homo sapiens	Q14919	Y2H Array	31467278
Intra	DR1	Q01658	STRN4	Homo sapiens	Q9NRL3	Validated Y2H	32814053
Intra	DR1	Q01658	STRN4	Homo sapiens	Q9NRL3	Y2H Pooling	32814053
Intra	DR1	Q01658	STRN4	Homo sapiens	Q9NRL3	Y2H Array	32814053
Intra	DR1	Q01658	MPC2	Homo sapiens	O95563	Validated Y2H	32814053
Intra	DR1	Q01658	MPC2	Homo sapiens	O95563	Y2H Array	32814053
Intra	DR1	Q01658	MPC2	Homo sapiens	O95563	Y2H Pooling	32814053
Intra	DR1	Q01658	RNF183	Homo sapiens	Q96D59	Validated Y2H	32814053
Intra	DR1	Q01658	RNF183	Homo sapiens	Q96D59	Y2H Array	32814053
Intra	DR1	Q01658	RNF183	Homo sapiens	Q96D59	Y2H Pooling	32814053
Intra	DR1	Q01658	POLE3	Homo sapiens	Q9NRF9	Complementation	32296183
Intra	DR1	Q01658	POLE3	Homo sapiens	Q9NRF9	Y2H Pooling	16189514
Intra	DR1	Q01658	POLE3	Homo sapiens	Q9NRF9	Validated Y2H	32296183
Intra	DR1	Q01658	ZNF581	Homo sapiens	Q9P0T4	Y2H Array	32814053
Intra	DR1	Q01658	ZNF581	Homo sapiens	Q9P0T4	Y2H Pooling	32814053
Intra	DR1	Q01658	ZNF581	Homo sapiens	Q9P0T4	Validated Y2H	32814053
Intra	DR1	Q01658	RAI2	Homo sapiens	Q9Y5P3	Y2H Pooling	32814053
Intra	DR1	Q01658	RAI2	Homo sapiens	Q9Y5P3	Validated Y2H	32814053
Intra	DR1	Q01658	RAI2	Homo sapiens	Q9Y5P3	Y2H Array	32814053
Intra	DR1	Q01658	TACO1	Homo sapiens	Q9BSH4	Y2H Pooling	32814053
Intra	DR1	Q01658	TACO1	Homo sapiens	Q9BSH4	Validated Y2H	32814053
Intra	DR1	Q01658	TACO1	Homo sapiens	Q9BSH4	Y2H Array	32814053
Intra	DR1	Q01658	GMPPA	Homo sapiens	Q96IJ6	Y2H Array	32814053
Intra	DR1	Q01658	GMPPA	Homo sapiens	Q96IJ6	Y2H Pooling	32814053
Intra	DR1	Q01658	GMPPA	Homo sapiens	Q96IJ6	Validated Y2H	32814053
Intra	DR1	Q01658	SEM1	Homo sapiens	P60896	Validated Y2H	32814053
Intra	DR1	Q01658	SEM1	Homo sapiens	P60896	Y2H Array	32814053
Intra	DR1	Q01658	SEM1	Homo sapiens	P60896	Y2H Pooling	32814053
Intra	DR1	Q01658	SPPL2B	Homo sapiens	Q8TCT7-2	Validated Y2H	32814053
Intra	DR1	Q01658	SPPL2B	Homo sapiens	Q8TCT7-2	Y2H Array	32814053
Intra	DR1	Q01658	SPPL2B	Homo sapiens	Q8TCT7-2	Y2H Pooling	32814053
Intra	DR1	Q01658	FAM9A	Homo sapiens	Q8IZU1	Validated Y2H	32814053
Intra	DR1	Q01658	FAM9A	Homo sapiens	Q8IZU1	Y2H Array	32814053
Intra	DR1	Q01658	FAM9A	Homo sapiens	Q8IZU1	Y2H Pooling	32814053
Intra	DR1	Q01658	TIMM44	Homo sapiens	O43615	Y2H Array	32814053
Intra	DR1	Q01658	TIMM44	Homo sapiens	O43615	Validated Y2H	32814053
Intra	DR1	Q01658	TIMM44	Homo sapiens	O43615	Y2H Pooling	32814053
Intra	DR1	Q01658	CSNK1D	Homo sapiens	P48730-2	Y2H Array	32814053
Intra	DR1	Q01658	CSNK1D	Homo sapiens	P48730-2	Validated Y2H	32814053
Intra	DR1	Q01658	CSNK1D	Homo sapiens	P48730-2	Y2H Pooling	32814053
Intra	DR1	Q01658	LOC401296	Homo sapiens	A2RU56	Y2H Array	32814053
Intra	DR1	Q01658	LOC401296	Homo sapiens	A2RU56	Y2H Pooling	32814053
Intra	DR1	Q01658	LOC401296	Homo sapiens	A2RU56	Validated Y2H	32814053

种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称

别名

Oesophagostomiasis

Infection By Oesophagostomum

Oesophagostomosis

Trichostrongylosis

Trichostrongyliasis	Infection By Trichostrongylus
Infection By Trichostrongylus Species	Trichostrongylus Infestation

Recessive Dystrophic Epidermolysis Bullosa

Autosomal Recessive Dystrophic Epidermolysis Bullosa Generalisata Gravis	Autosomal Recessive Dystrophic Epidermolysis Bullosa, Hallopeau-Siemens Type
Rdeb, Hallopeau-Siemens Type	Severe Generalized Rdeb
Severe Generalized Recessive Dystrophic Epidermolysis Bullosa	Rdeb Generalisata Gravis
Rdeb, Severe Generalized	Rdeb-Sev Gen
Recessive Dystrophic Epidermolysis Bullosa, Severe Generalized	Hallopeau-Siemens Disease

Epidermolysis Bullosa Dystrophica, Pretibial

Epidermolysis Bullosa, Pretibial	Pretibial Dystrophic Epidermolysis Bullosa
Deb-Pt	Dystrophic Epidermolysis Bullosa, Pretibial
Deb, Pretibial	Pretibial Epidermolysis Bullosa
Pretibial Deb	Localized Dystrophic Epidermolysis Bullosa, Pretibial Form
Localized Deb, Pretibial Form	Epidermolysis Bullosa Dystrophica, Pretibial Type
PR-DEB

Corneal Dystrophy, Subepithelial Mucinous

Subepithelial Mucinous Corneal Dystrophy

SMCD

Spondyloepimetaphyseal Dysplasia, Strudwick Type

Spondylometaphyseal Dysplasia	Strudwick Syndrome
Dappled Metaphysis Syndrome	Semd, Strudwick Type
Spondylometaepiphyseal Dysplasia Congenita, Strudwick Type	Smed, Strudwick Type
Smd	Smed Strudwick Type
SEMDSTWK	Smed, Type I
Semdc	Smed Type 1
Spondyloepimetaphyseal Dysplasia Strudwick Type	Sed Strudwick
Spondyloepimetaphyseal Dysplasia Congenita, Strudwick Type	Smed Type I
Spondyloepiphyseal Dysplasia Congenita With Dappled Metaphyses	Dysplasia, Spondyloepimetaphyseal, Strudwick Type
Dysplasia, Spondylometaphyseal

Trichostrongyloidiasis

Anisakiasis

Infection By Anisakis Larva	Anisakis Infection
Pseudoterranova Infection	Anisakiasis Due To Anisakis Simplex
Anisakiasis Due To Pseudoterranova Decipiens	Anisakis Infestation
Infection Due To Anisakis Larvae

Metaphyseal Chondrodysplasia, Schmid Type

MCDS	Schmid Metaphyseal Chondrodysplasia
Metaphyseal Chondrodysplasia Schmid Type	Spondylometaphyseal Dysplasia, Japanese Type
Japanese Type Spondylometaphyseal Dysplasia	Schmid Type Metaphyseal Dysplasia
Metaphyseal Chondrodysplasia Type Schmid	Schmid Type Metaphyseal Chondrodysplasia
SMCD	Chondrodysplasia, Metaphyseal, Schmid Type
Corneal Dystrophy, Subepithelial Mucinous

Ancylostomiasis

Ankylostomiasis	Hookworm Infection
Hookworm Infections	Ancylostomiasis Due To Ancylostoma Duodenale
Ancylostoma Duodenale Infection

Transient Bullous Dermolysis Of The Newborn

TBDN	Transient Bullous Of The Newborn
Epidermolysis Bullosa Dystrophica, Neonatal Form	Dystrophic Epidermolysis Bullosa, Neonatal
Deb, Bullous Dermolysis Of The Newborn	Deb-Bdn
Epidermolysis Bullosa Dystrophica, Dominant Neonatal Form	Self-Improving Dystrophic Epidermolysis Bullosa
Self-Improving Deb	Epidermolysis Bullosa Dystrophica Dominant Neonatal Type

Traumatic Glaucoma

Glaucoma Associated With Ocular Trauma

Epidermolysis Bullosa Dystrophica

Dystrophic Epidermolysis Bullosa	Deb
Dermolytic Epidermolysis Bullosa	Epidermolysis Bullosa, Dermolytic
Epidermolysis Bullosa, Dystrophic	Epidermolysis Bullosa Dystrophic
Dystrophic Eb - [Epidermolysis Bullosa]

Internal Hordeolum

Noonan Syndrome 2

NS2	Noonan Syndrome, Autosomal Recessive
Noonan Syndrome 2, Autosomal Recessive	Noonan Syndrome, Type 2

Hypoparathyroidism-Deafness-Renal Disease Syndrome

Barakat Syndrome	Hypoparathyroidism, Deafness, Renal Disease Syndrome
Hdr Syndrome	Hypoparathyroidism, Sensorineural Deafness, And Renal Disease

Acquired Color Blindness

Acquired Color Vision Deficiencies	Acquired Color Vision Deficiency
Acquired Colour Blindness	Acquired Colour Vision Deficiencies
Acquired Colour Vision Deficiency

Toxocariasis

Toxocara Infection	Visceral Larva Migrans
Larva Migrans, Visceral	Infection By Toxascaris
Larva Migrans Visceral	Larva Migrans Visceralis
Toxocaral Visceral Larva Migrans	Visceral Larva Migrans Syndrome
Toxocara Infestation

Bullous Skin Disease

Skin Diseases Bullous

Skin Diseases, Bullous

Epithelial And Subepithelial Dystrophy

疾病名称	别名
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	产品名	作用方式	纯度	是否罕见病
HY-150069	UBX1325		99.16%	否
HY-139170	CAY10746	Inhibitor	99.77%	否
HY-157269	J10-1		/	否
HY-RS03986	DR1 Human Pre-designed siRNA Set A	Pre-designed Sets	/	否

直系同源

种属	基因名	来源	基因 ID
Felis catus	DR1	VGNC	VGNC:80190
Mus musculus	DR1	MGD	MGI:1100515
Bos taurus	DR1	VGNC	VGNC:28200
Rattus norvegicus	DR1	RGD	RGD:1305201
Canis familiaris	DR1	VGNC	VGNC:40087
Others	DR1	NCBI

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