2. Gene
  3. MAP1LC3B - microtubule associated protein 1 light chain 3 beta Gene

MAP1LC3B - microtubule associated protein 1 light chain 3 beta Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：微管相关蛋白 1 轻链 3 beta

种属: Homo sapiens

同用名: LC3B; ATG8F; MAP1LC3B-a; MAP1A/1BLC3

基因 ID: 81631 | 基因类型: protein coding

关于 MAP1LC3B

Cytogenetic location: 16q24.2 Genomic coordinates (GRCh38): 16:87,392,336-87,404,774 (from NCBI)

This gene has 6 transcripts (splice variants), 173 orthologues and 6 paralogues. Ubiquitous expression in bone marrow (RPKM 94.3), brain (RPKM 58.8) and 25 other tissues.

功能概要

该基因的产物是神经元微管相关 MAP1A 和 MAP1B 蛋白的亚基，它们参与微管组装，对神经发生很重要。对大鼠同系物的研究暗示了该基因在自噬中的作用，自噬是一种涉及细胞质成分大量降解的过程。[RefSeq 提供，2008 年 7 月]

The product of this gene is a subunit of neuronal microtubule-associated MAP1A and MAP1B proteins, which are involved in microtubule assembly and important for neurogenesis. Studies on the rat homolog implicate a role for this gene in Autophagy, a process that involves the bulk degradation of cytoplasmic component. [provided by RefSeq, Jul 2008]

MAP1LC3B 基因产物(1)

mRNA Protein Name
NM_022818.5 NP_073729.1 microtubule-associated proteins 1A/1B light chain 3B

MAP1LC3B 蛋白结构

Atg8

Atg8: Autophagy protein Atg8 ubiquitin like (15 - 120)

  • 0
  • 100
  • 125 a.a.
蛋白主名 其他名称

microtubule-associated proteins 1A/1B light chain 3B

MAP1 light chain 3-like protein 2

重组 MAP1LC3B 蛋白

目录号 产品名 蛋白编号 纯度
HY-P70909 MAP1LC3B Protein, Human Q9GZQ8 (M1-V125) ≥95%

关联疾病

疾病名称 别名
Liver Carcinoma In Situ

Carcinoma In Situ Of Liver And Biliary System

Carcinoma In Situ Of Liver, Gallbladder And Bile Ducts
Parkinson Disease, Late-Onset

Parkinson Disease

Parkinson'S Disease

PD

PARK

Parkinson Disease, Susceptibility To

Late Onset Parkinson'S Disease

Late Onset Parkinson Disease

Paralysis Agitans

Primary Parkinsonism

Idiopathic Parkinson Disease

Parkinson'S

Parkinson Disease, Late-Onset, Susceptibility To

Parkinson Disease, Age Of Onset, Modifier

Lewy Body Parkinson Disease

Idiopathic Parkinson'S Disease

Pd - [Parkinson Disease]

Parkinson Disease Nos

Parkinson, Nos

Primary Parkinson Disease
Amyotrophic Lateral Sclerosis 1

Amyotrophic Lateral Sclerosis

ALS

Lou Gehrig Disease

Amyotrophic Lateral Sclerosis Type 1

Charcot Disease

ALS1

Amyotrophic Lateral Sclerosis, Susceptibility To

Fals

Lou Gehrig'S Disease

Mnd

Motor Neuron Disease

Familial Amyotrophic Lateral Sclerosis

Amyotrophic Lateral Sclerosis 1, Familial

Amyotrophic Lateral Sclerosis 1, Autosomal Dominant

Motor Neuron Disease, Bulbar

Motor Neurone Disease

Amyotrophic Lateral Sclerosis With Dementia

Dementia With Amyotrophic Lateral Sclerosis

Motor Neuron Disease, Amyotrophic Lateral Sclerosis

Sclerosis, Lateral, Amyotrophic

Sclerosis, Lateral, Amyotrophic, Type 1

Amyotrophic Sclerosis

Als - [Amyotrophic Lateral Sclerosis]

Wasting Palsy

Amyotrophic Paralysis

Amyotrophy Lateral Sclerosis

Wasting Paralysis

Spinal Progressive Amyotrophy

Progressive Atrophic Paralysis
Nervous System Disease

Abnormality Of The Nervous System

Nervous System Diseases

Nervous System Disorder
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (2)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS08029 MAP1LC3B Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS08030 MAP1LC3B2 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus MAP1LC3B RGD RGD:621315
Mus musculus MAP1LC3B MGD MGI:1914693
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