1. Gene
  2. PRKAA2 - protein kinase AMP-activated catalytic subunit alpha 2 Gene

PRKAA2 - protein kinase AMP-activated catalytic subunit alpha 2 Gene

中文名称:蛋白激酶 AMP 激活的催化亚基 alpha 2

种属: Homo sapiens

同用名: AMPK; AMPK2; PRKAA; AMPKa2

基因 ID: 5563 | 基因类型: protein coding

关于 PRKAA2

Cytogenetic location: 1p32.2 Genomic coordinates (GRCh38): 1:56,645,314-56,715,335 (from NCBI)

This gene has 1 transcript (splice variant), 222 orthologues and 17 paralogues. Biased expression in heart (RPKM 14.0), kidney (RPKM 6.8) and 8 other tissues.

功能概要

该基因编码的蛋白质是 AMP 活化蛋白激酶 (AMPK) 的催化亚基。 AMPK 是一种异源三聚体,由一个 α 催化亚基以及非催化 β 和 γ 亚基组成。 AMPK 是一种重要的能量感应酶,可监测细胞能量状态。响应细胞代谢应激,AMPK 被激活,从而使乙酰辅酶 A 羧化酶 (ACC) 和 β-羟基β-甲基戊二酰辅酶 A 还原酶 (HMGCR) 磷酸化和失活,这些酶是参与调节脂肪酸和胆固醇从头生物合成的关键酶.对小鼠对应物的研究表明,这种催化亚基可以控制全身胰岛素敏感性,并且是在缺血期间维持心肌能量稳态所必需的。[RefSeq 提供,2008 年 7 月]

The protein encoded by this gene is a catalytic subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing Enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates Acetyl-CoA Carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key Enzymes involved in regulating de novo biosynthesis of fatty acid and Cholesterol. Studies of the mouse counterpart suggest that this catalytic subunit may control whole-body Insulin sensitivity and is necessary for maintaining myocardial energy homeostasis during ischemia. [provided by RefSeq, Jul 2008]

PRKAA2 基因产物(1)

mRNA Protein Name
NM_006252.4 NP_006243.2 5'-AMP-activated protein kinase catalytic subunit alpha-2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables AMP-activated protein kinase activity IDA
IDA: 通过直接分析推断
14651849 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
18439900 GOA
enables protein serine/threonine kinase activity IDA
IDA: 通过直接分析推断
18439900 GOA
enables protein serine/threonine/tyrosine kinase activity IDA
IDA: 通过直接分析推断
22797923 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to glucose starvation IDA
IDA: 通过直接分析推断
14651849 GOA
involved in cellular response to nutrient levels IDA
IDA: 通过直接分析推断
25412657 GOA
acts upstream of positive effect lipid droplet disassembly IDA
IDA: 通过直接分析推断
34077757 GOA
involved in negative regulation of TORC1 signaling IDA
IDA: 通过直接分析推断
14651849 GOA
involved in negative regulation of hepatocyte apoptotic process IDA
IDA: 通过直接分析推断
32029622 GOA
involved in protein localization to lipid droplet IDA
IDA: 通过直接分析推断
34077757 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of nucleotide-activated protein kinase complex IPI
IPI: 通过物理相互作用推断
9693118 GOA
located in nucleus IDA
IDA: 通过直接分析推断
9693118 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

PRKAA2 蛋白结构

Pkinase

Pkinase: Protein kinase domain (16 - 268)

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  • 552 a.a.
蛋白主名 其他名称

5'-AMP-activated protein kinase catalytic subunit alpha-2

5'-AMP-activated protein kinase, catalytic alpha-2 chain

PRKAA2 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
PRKAA2 P54646 HOMEZ Homo sapiens Q8IX15-3 25416956
种属内
PRKAA2 P54646 KRTAP10-9 Homo sapiens P60411 32296183
种属内
PRKAA2 P54646 KRTAP10-9 Homo sapiens P60411 32296183
种属内
PRKAA2 P54646 KRTAP10-9 Homo sapiens P60411 32296183
种属内
PRKAA2 P54646 NECAB2 Homo sapiens Q7Z6G3-2 25416956
种属内
PRKAA2 P54646 NUTM1 Homo sapiens Q86Y26 25416956
种属内
PRKAA2 P54646 CDX4 Homo sapiens O14627 32296183
种属内
PRKAA2 P54646 CDX4 Homo sapiens O14627 32296183
种属内
PRKAA2 P54646 FOS Homo sapiens Q6FG41 25416956
种属内
PRKAA2 P54646 FOS Homo sapiens Q6FG41 25416956
种属内
PRKAA2 P54646 KIF24 Homo sapiens Q5T7B8-2 25416956
种属内
PRKAA2 P54646 KIF24 Homo sapiens Q5T7B8-2 25416956
种属内
PRKAA2 P54646 ZNF397 Homo sapiens Q8NF99 25416956
种属内
PRKAA2 P54646 ZNF397 Homo sapiens Q8NF99 25416956
种属内
PRKAA2 P54646 DNAAF6 Homo sapiens Q9NQM4 32296183
种属内
PRKAA2 P54646 DNAAF6 Homo sapiens Q9NQM4 32296183
种属内
PRKAA2 P54646 DNAAF6 Homo sapiens Q9NQM4 32296183
种属内
PRKAA2 P54646 FNDC3B Homo sapiens Q53EP0-3 32296183
种属内
PRKAA2 P54646 FNDC3B Homo sapiens Q53EP0-3 32296183
种属内
PRKAA2 P54646 FNDC3B Homo sapiens Q53EP0-3 32296183
种属内
PRKAA2 P54646 PRKAB2 Homo sapiens O43741 25416956
种属内
PRKAA2 P54646 PRKAB2 Homo sapiens O43741 32707033
种属内
PRKAA2 P54646 PRKAB2 Homo sapiens O43741 25416956
种属内
PRKAA2 P54646 PRKAB2 Homo sapiens O43741 20562859
种属内
PRKAA2 P54646 REL Homo sapiens Q04864-2 32296183
种属内
PRKAA2 P54646 REL Homo sapiens Q04864-2 32296183
种属内
PRKAA2 P54646 REL Homo sapiens Q04864-2 30886144
种属内
PRKAA2 P54646 REL Homo sapiens Q04864-2 32296183
种属内
PRKAA2 P54646 KIF16B Homo sapiens Q96L93-6 32296183
种属内
PRKAA2 P54646 KIF16B Homo sapiens Q96L93-6 32296183
种属内
PRKAA2 P54646 KIF16B Homo sapiens Q96L93-6 32296183
种属内
PRKAA2 P54646 CDC42EP1 Homo sapiens Q00587-2 32296183
种属内
PRKAA2 P54646 CDC42EP1 Homo sapiens Q00587-2 32296183
种属内
PRKAA2 P54646 CDC42EP1 Homo sapiens Q00587-2 32296183
种属内
PRKAA2 P54646 ABI2 Homo sapiens Q9NYB9-2 32296183
种属内
PRKAA2 P54646 ABI2 Homo sapiens Q9NYB9-2 32296183
种属内
PRKAA2 P54646 ABI2 Homo sapiens Q9NYB9-2 32296183
种属内
PRKAA2 P54646 GOLGA6A Homo sapiens Q9NYA3 32296183
种属内
PRKAA2 P54646 GOLGA6A Homo sapiens Q9NYA3 32296183
种属内
PRKAA2 P54646 GOLGA6A Homo sapiens Q9NYA3 32296183
种属内
PRKAA2 P54646 PRDM6 Homo sapiens Q9NQX0 32296183
种属内
PRKAA2 P54646 PRDM6 Homo sapiens Q9NQX0 32296183
种属内
PRKAA2 P54646 PRDM6 Homo sapiens Q9NQX0 32296183
种属内
PRKAA2 P54646 IKZF1 Homo sapiens Q13422-7 32296183
种属内
PRKAA2 P54646 IKZF1 Homo sapiens Q13422-7 32296183
种属内
PRKAA2 P54646 IKZF1 Homo sapiens Q13422-7 32296183
种属内
PRKAA2 P54646 MTUS2 Homo sapiens Q5JR59-3 30886144
种属内
PRKAA2 P54646 MTUS2 Homo sapiens Q5JR59-3 32296183
种属内
PRKAA2 P54646 MTUS2 Homo sapiens Q5JR59-3 32296183
种属内
PRKAA2 P54646 MTUS2 Homo sapiens Q5JR59-3 32296183
种属内
PRKAA2 P54646 USH1C Homo sapiens Q9Y6N9-4 32296183
种属内
PRKAA2 P54646 USH1C Homo sapiens Q9Y6N9-4 32296183
种属内
PRKAA2 P54646 USH1C Homo sapiens Q9Y6N9-4 32296183
种属内
PRKAA2 P54646 CPSF7 Homo sapiens Q8N684-3 32296183
种属内
PRKAA2 P54646 CPSF7 Homo sapiens Q8N684-3 32296183
种属内
PRKAA2 P54646 CPSF7 Homo sapiens Q8N684-3 32296183
种属内
PRKAA2 P54646 TLE5 Homo sapiens Q08117-2 32296183
种属内
PRKAA2 P54646 TLE5 Homo sapiens Q08117-2 32296183
种属内
PRKAA2 P54646 TLE5 Homo sapiens Q08117-2 32296183
种属内
PRKAA2 P54646 ABI1 Homo sapiens Q8IZP0-5 32296183
种属内
PRKAA2 P54646 ABI1 Homo sapiens Q8IZP0-5 32296183
种属内
PRKAA2 P54646 ABI1 Homo sapiens Q8IZP0-5 32296183
种属内
PRKAA2 P54646 EMILIN1 Homo sapiens Q9Y6C2-2 32296183
种属内
PRKAA2 P54646 EMILIN1 Homo sapiens Q9Y6C2-2 32296183
种属内
PRKAA2 P54646 EMILIN1 Homo sapiens Q9Y6C2-2 32296183
种属内
PRKAA2 P54646 KRTAP1-3 Homo sapiens Q8IUG1 32296183
种属内
PRKAA2 P54646 KRTAP1-3 Homo sapiens Q8IUG1 32296183
种属内
PRKAA2 P54646 CDR2 Homo sapiens Q01850 32296183
种属内
PRKAA2 P54646 CDR2 Homo sapiens Q01850 32296183
种属内
PRKAA2 P54646 CDR2 Homo sapiens Q01850 32296183
种属内
PRKAA2 P54646 PRKAG1 Homo sapiens P54619 31515488
种属内
PRKAA2 P54646 PRKAG1 Homo sapiens P54619 25416956
种属内
PRKAA2 P54646 PRKAG1 Homo sapiens P54619 32707033
种属内
PRKAA2 P54646 PRKAG1 Homo sapiens P54619 20562859
种属内
PRKAA2 P54646 LCN2 Homo sapiens P80188 32296183
种属内
PRKAA2 P54646 LCN2 Homo sapiens P80188 32296183
种属内
PRKAA2 P54646 LCN2 Homo sapiens P80188 32296183
种属内
PRKAA2 P54646 L3MBTL3 Homo sapiens Q96JM7-2 32296183
种属内
PRKAA2 P54646 L3MBTL3 Homo sapiens Q96JM7-2 32296183
种属内
PRKAA2 P54646 L3MBTL3 Homo sapiens Q96JM7-2 32296183
种属内
PRKAA2 P54646 SAXO4 Homo sapiens Q7Z5V6-2 32296183
种属内
PRKAA2 P54646 SAXO4 Homo sapiens Q7Z5V6-2 32296183
种属内
PRKAA2 P54646 SAXO4 Homo sapiens Q7Z5V6-2 32296183
种属内
PRKAA2 P54646 PLEKHN1 Homo sapiens Q494U1-3 32296183
种属内
PRKAA2 P54646 PLEKHN1 Homo sapiens Q494U1-3 32296183
种属内
PRKAA2 P54646 PLEKHN1 Homo sapiens Q494U1-3 32296183
种属内
PRKAA2 P54646 ZMYND12 Homo sapiens Q9H0C1 32296183
种属内
PRKAA2 P54646 ZMYND12 Homo sapiens Q9H0C1 32296183
种属内
PRKAA2 P54646 ZMYND12 Homo sapiens Q9H0C1 32296183
种属内
PRKAA2 P54646 EPN2 Homo sapiens O95208-2 32296183
种属内
PRKAA2 P54646 EPN2 Homo sapiens O95208-2 32296183
种属内
PRKAA2 P54646 VPS28 Homo sapiens Q9UK41-2 32296183
种属内
PRKAA2 P54646 VPS28 Homo sapiens Q9UK41-2 32296183
种属内
PRKAA2 P54646 VPS28 Homo sapiens Q9UK41-2 32296183
种属内
PRKAA2 P54646 ANAPC11 Homo sapiens Q9NYG5-2 32296183
种属内
PRKAA2 P54646 ANAPC11 Homo sapiens Q9NYG5-2 32296183
种属内
PRKAA2 P54646 ANAPC11 Homo sapiens Q9NYG5-2 32296183
种属内
PRKAA2 P54646 SLA2 Homo sapiens Q9H6Q3 32296183
种属内
PRKAA2 P54646 SLA2 Homo sapiens Q9H6Q3 32296183
种属内
PRKAA2 P54646 SLA2 Homo sapiens Q9H6Q3 32296183
种属内
PRKAA2 P54646 CTAG2 Homo sapiens O75638-2 32296183
种属内
PRKAA2 P54646 CTAG2 Homo sapiens O75638-2 32296183
种属内
PRKAA2 P54646 SOHLH1 Homo sapiens Q5JUK2 32296183
种属内
PRKAA2 P54646 SOHLH1 Homo sapiens Q5JUK2 32296183
种属内
PRKAA2 P54646 SOHLH1 Homo sapiens Q5JUK2 32296183
种属内
PRKAA2 P54646 ZNF212 Homo sapiens Q9UDV6 32296183
种属内
PRKAA2 P54646 ZNF212 Homo sapiens Q9UDV6 32296183
种属内
PRKAA2 P54646 ZNF212 Homo sapiens Q9UDV6 32296183
种属内
PRKAA2 P54646 AMOT Homo sapiens A2BDD9 32296183
种属内
PRKAA2 P54646 AMOT Homo sapiens A2BDD9 32296183
种属内
PRKAA2 P54646 MYCL Homo sapiens P12524-2 32296183
种属内
PRKAA2 P54646 MYCL Homo sapiens P12524-2 32296183
种属内
PRKAA2 P54646 KIFC3 Homo sapiens Q9BVG8 25416956
种属内
PRKAA2 P54646 MKRN3 Homo sapiens Q13064 32296183
种属内
PRKAA2 P54646 MKRN3 Homo sapiens Q13064 32296183
种属内
PRKAA2 P54646 MKRN3 Homo sapiens Q13064 32296183
种属内
PRKAA2 P54646 NRBF2 Homo sapiens Q96F24 32296183
种属内
PRKAA2 P54646 NRBF2 Homo sapiens Q96F24 32296183
种属内
PRKAA2 P54646 NRBF2 Homo sapiens Q96F24 32296183
种属内
PRKAA2 P54646 CCDC172 Homo sapiens P0C7W6 32296183
种属内
PRKAA2 P54646 CCDC172 Homo sapiens P0C7W6 32296183
种属内
PRKAA2 P54646 L3MBTL3 Homo sapiens Q96JM7 25416956
种属内
PRKAA2 P54646 VPS52 Homo sapiens Q8N1B4 25416956
种属内
PRKAA2 P54646 VPS52 Homo sapiens Q8N1B4 25416956
种属内
PRKAA2 P54646 PRKAR1B Homo sapiens P31321 32296183
种属内
PRKAA2 P54646 PRKAR1B Homo sapiens P31321 32296183
种属内
PRKAA2 P54646 ARRDC3 Homo sapiens Q96B67 32296183
种属内
PRKAA2 P54646 ARRDC3 Homo sapiens Q96B67 32296183
种属内
PRKAA2 P54646 ARRDC3 Homo sapiens Q96B67 32296183
种属内
PRKAA2 P54646 GLI1 Homo sapiens P08151 25416956
种属内
PRKAA2 P54646 GLI1 Homo sapiens P08151 25416956
种属内
PRKAA2 P54646 KIAA1328 Homo sapiens Q86T90 32296183
种属内
PRKAA2 P54646 KIAA1328 Homo sapiens Q86T90 32296183
种属内
PRKAA2 P54646 KIAA1328 Homo sapiens Q86T90 32296183
种属内
PRKAA2 P54646 RASAL3 Homo sapiens Q86YV0 32296183
种属内
PRKAA2 P54646 RASAL3 Homo sapiens Q86YV0 32296183
种属内
PRKAA2 P54646 RASAL3 Homo sapiens Q86YV0 32296183
种属内
PRKAA2 P54646 DNM2 Homo sapiens P50570 32296183
种属内
PRKAA2 P54646 DNM2 Homo sapiens P50570 32296183
种属内
PRKAA2 P54646 KRT16 Homo sapiens P08779 32296183
种属内
PRKAA2 P54646 KRT16 Homo sapiens P08779 32296183
种属内
PRKAA2 P54646 YWHAE Homo sapiens P62258 36931259
种属内
PRKAA2 P54646 AKAP8L Homo sapiens Q9ULX6 32296183
种属内
PRKAA2 P54646 AKAP8L Homo sapiens Q9ULX6 32296183
种属内
PRKAA2 P54646 AKAP8L Homo sapiens Q9ULX6 32296183
种属内
PRKAA2 P54646 TRIP13 Homo sapiens Q15645 32296183
种属内
PRKAA2 P54646 TRIP13 Homo sapiens Q15645 32296183
种属内
PRKAA2 P54646 TRIP13 Homo sapiens Q15645 32296183
种属内
PRKAA2 P54646 SKIC2 Homo sapiens Q15477 32296183
种属内
PRKAA2 P54646 SKIC2 Homo sapiens Q15477 32296183
种属内
PRKAA2 P54646 SKIC2 Homo sapiens Q15477 32296183
种属内
PRKAA2 P54646 SPRY1 Homo sapiens O43609 32296183
种属内
PRKAA2 P54646 SPRY1 Homo sapiens O43609 32296183
种属内
PRKAA2 P54646 CYSRT1 Homo sapiens A8MQ03 32296183
种属内
PRKAA2 P54646 CYSRT1 Homo sapiens A8MQ03 32296183
种属内
PRKAA2 P54646 RNF11 Homo sapiens Q9Y3C5 32814053
种属内
PRKAA2 P54646 RNF11 Homo sapiens Q9Y3C5 32814053
种属内
PRKAA2 P54646 RNF11 Homo sapiens Q9Y3C5 32814053
种属内
PRKAA2 P54646 KCTD9 Homo sapiens Q7L273 32296183
种属内
PRKAA2 P54646 KCTD9 Homo sapiens Q7L273 32296183
种属内
PRKAA2 P54646 KCTD9 Homo sapiens Q7L273 32296183
种属内
PRKAA2 P54646 VPS37B Homo sapiens Q9H9H4 32296183
种属内
PRKAA2 P54646 VPS37B Homo sapiens Q9H9H4 32296183
种属内
PRKAA2 P54646 VPS37B Homo sapiens Q9H9H4 32296183
种属内
PRKAA2 P54646 TCF4 Homo sapiens P15884 25416956
种属内
PRKAA2 P54646 ZSCAN23 Homo sapiens Q3MJ62 32296183
种属内
PRKAA2 P54646 ZSCAN23 Homo sapiens Q3MJ62 32296183
种属内
PRKAA2 P54646 ZSCAN23 Homo sapiens Q3MJ62 32296183
种属内
PRKAA2 P54646 GOLGA2 Homo sapiens Q08379 32296183
种属内
PRKAA2 P54646 GOLGA2 Homo sapiens Q08379 32296183
种属内
PRKAA2 P54646 GOLGA2 Homo sapiens Q08379 32296183
种属内
PRKAA2 P54646 TLE5 Homo sapiens Q08117 25416956
种属内
PRKAA2 P54646 TLE5 Homo sapiens Q08117 25416956
种属内
PRKAA2 P54646 PRKAB1 Homo sapiens Q9Y478 32296183
种属内
PRKAA2 P54646 PRKAB1 Homo sapiens Q9Y478 32707033
种属内
PRKAA2 P54646 PRKAB1 Homo sapiens Q9Y478 32296183
种属内
PRKAA2 P54646 PRKAB1 Homo sapiens Q9Y478 32296183
种属内
PRKAA2 P54646 WFS1 Homo sapiens O76024 32814053
种属内
PRKAA2 P54646 WFS1 Homo sapiens O76024 32814053
种属内
PRKAA2 P54646 WFS1 Homo sapiens O76024 32814053
种属内
PRKAA2 P54646 TSC22D4 Homo sapiens Q9Y3Q8 25416956
种属内
PRKAA2 P54646 TSC22D4 Homo sapiens Q9Y3Q8 25416956
种属内
PRKAA2 P54646 CALCOCO2 Homo sapiens Q13137 32296183
种属内
PRKAA2 P54646 CALCOCO2 Homo sapiens Q13137 32296183
种属内
PRKAA2 P54646 CALCOCO2 Homo sapiens Q13137 32296183
种属内
PRKAA2 P54646 DVL3 Homo sapiens Q92997 32296183
种属内
PRKAA2 P54646 DVL3 Homo sapiens Q92997 32296183
种属内
PRKAA2 P54646 DVL3 Homo sapiens Q92997 32296183
种属内
PRKAA2 P54646 RBPMS Homo sapiens Q93062 25416956
种属内
PRKAA2 P54646 GRAP2 Homo sapiens O75791 32296183
种属内
PRKAA2 P54646 GRAP2 Homo sapiens O75791 32296183
种属内
PRKAA2 P54646 TIFA Homo sapiens Q96CG3 32296183
种属内
PRKAA2 P54646 TIFA Homo sapiens Q96CG3 32296183
种属内
PRKAA2 P54646 TIFA Homo sapiens Q96CG3 32296183
种属内
PRKAA2 P54646 LZTS2 Homo sapiens Q9BRK4 32296183
种属内
PRKAA2 P54646 LZTS2 Homo sapiens Q9BRK4 32296183
种属内
PRKAA2 P54646 LZTS2 Homo sapiens Q9BRK4 32296183
种属内
PRKAA2 P54646 TRIP6 Homo sapiens Q15654 25416956
种属内
PRKAA2 P54646 ZBTB8A Homo sapiens Q96BR9 25416956
种属内
PRKAA2 P54646 ZBTB8A Homo sapiens Q96BR9 25416956
种属内
PRKAA2 P54646 ZBTB8A Homo sapiens Q96BR9 25416956
种属内
PRKAA2 P54646 ABI2 Homo sapiens Q9NYB9 25416956
种属内
PRKAA2 P54646 ABI2 Homo sapiens Q9NYB9 29892012
种属内
PRKAA2 P54646 APPBP2 Homo sapiens Q92624 25416956
种属内
PRKAA2 P54646 APPBP2 Homo sapiens Q92624 25416956
种属内
PRKAA2 P54646 APPBP2 Homo sapiens Q92624 25416956
种属内
PRKAA2 P54646 WWP2 Homo sapiens O00308 32296183
种属内
PRKAA2 P54646 WWP2 Homo sapiens O00308 32296183
种属内
PRKAA2 P54646 CCNB1IP1 Homo sapiens Q9NPC3 31515488
种属内
PRKAA2 P54646 CCNB1IP1 Homo sapiens Q9NPC3 25416956
种属内
PRKAA2 P54646 RFX6 Homo sapiens Q8HWS3 25416956
种属内
PRKAA2 P54646 RFX6 Homo sapiens Q8HWS3 25416956
种属内
PRKAA2 P54646 AMOTL2 Homo sapiens Q9Y2J4 32296183
种属内
PRKAA2 P54646 AMOTL2 Homo sapiens Q9Y2J4 32296183
种属内
PRKAA2 P54646 AMOTL2 Homo sapiens Q9Y2J4 32296183
种属内
PRKAA2 P54646 IKZF3 Homo sapiens Q9UKT9 32296183
种属内
PRKAA2 P54646 IKZF3 Homo sapiens Q9UKT9 32296183
种属内
PRKAA2 P54646 IKZF3 Homo sapiens Q9UKT9 32296183
种属内
PRKAA2 P54646 GRN Homo sapiens P28799 32814053
种属内
PRKAA2 P54646 GRN Homo sapiens P28799 32814053
种属内
PRKAA2 P54646 GRN Homo sapiens P28799 32814053
种属内
PRKAA2 P54646 SERTAD3 Homo sapiens Q9UJW9 32296183
种属内
PRKAA2 P54646 SERTAD3 Homo sapiens Q9UJW9 32296183
种属内
PRKAA2 P54646 SERTAD3 Homo sapiens Q9UJW9 32296183
种属内
PRKAA2 P54646 CALCOCO1 Homo sapiens Q9P1Z2 32296183
种属内
PRKAA2 P54646 CALCOCO1 Homo sapiens Q9P1Z2 32296183
种属内
PRKAA2 P54646 CALCOCO1 Homo sapiens Q9P1Z2 32296183
种属内
PRKAA2 P54646 PRPH Homo sapiens P41219 32296183
种属内
PRKAA2 P54646 PRPH Homo sapiens P41219 32296183
种属内
PRKAA2 P54646 USH1G Homo sapiens Q495M9 32296183
种属内
PRKAA2 P54646 USH1G Homo sapiens Q495M9 32296183
种属内
PRKAA2 P54646 USH1G Homo sapiens Q495M9 32296183
种属间
PRKAA2 P54646 Stk11 Mus musculus Q9WTK7 19274086
种属内
PRKAA2 P54646 AVPI1 Homo sapiens Q5T686 32296183
种属内
PRKAA2 P54646 AVPI1 Homo sapiens Q5T686 32296183
种属内
PRKAA2 P54646 AVPI1 Homo sapiens Q5T686 32296183
种属内
PRKAA2 P54646 NAB2 Homo sapiens Q15742 32296183
种属内
PRKAA2 P54646 NAB2 Homo sapiens Q15742 32296183
种属内
PRKAA2 P54646 NAB2 Homo sapiens Q15742 32296183
种属内
PRKAA2 P54646 KCTD1 Homo sapiens Q719H9 25416956
种属内
PRKAA2 P54646 KCTD1 Homo sapiens Q719H9 25416956
种属内
PRKAA2 P54646 ULK1 Homo sapiens O75385 21072212
种属内
PRKAA2 P54646 ULK1 Homo sapiens O75385 20562859
种属内
PRKAA2 P54646 NOTCH2NLA Homo sapiens Q7Z3S9 25416956
种属内
PRKAA2 P54646 GIGYF1 Homo sapiens O75420 32296183
种属内
PRKAA2 P54646 GIGYF1 Homo sapiens O75420 32296183
种属内
PRKAA2 P54646 KRT31 Homo sapiens Q15323 25416956
种属内
PRKAA2 P54646 KRT31 Homo sapiens Q15323 25416956
种属内
PRKAA2 P54646 STAC2 Homo sapiens Q6ZMT1 32296183
种属内
PRKAA2 P54646 STAC2 Homo sapiens Q6ZMT1 32296183
种属内
PRKAA2 P54646 STAC2 Homo sapiens Q6ZMT1 32296183
种属内
PRKAA2 P54646 MORN3 Homo sapiens Q6PF18 32296183
种属内
PRKAA2 P54646 MORN3 Homo sapiens Q6PF18 32296183
种属内
PRKAA2 P54646 MORN3 Homo sapiens Q6PF18 32296183
种属内
PRKAA2 P54646 MRFAP1 Homo sapiens Q9Y605 32296183
种属内
PRKAA2 P54646 MRFAP1 Homo sapiens Q9Y605 32296183
种属内
PRKAA2 P54646 MRFAP1 Homo sapiens Q9Y605 32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

重组 PRKAA2 蛋白

目录号 产品名 蛋白编号 纯度
HY-P76142 AMPK gamma 1/beta 1/alpha 2 Heterotrimer Protein, Human (sf9, His-GST) P54619 (M1-P331)&Q9Y478 (M1-I270)&P54646 (M1-R552) ≥95%
HY-P76144 AMPK gamma 1/beta 2/alpha 2 Heterotrimer Protein, Human (sf9, His-GST) P54619 (M1-P331)&O43741 (M1-I272)&P54646 (M1-R552) ≥95%

PRKAA2 抗体

目录号 产品名 应用 反应物种
HY-P80540 AMPK alpha 2 Antibody (YA623) WB, IP Human, Rat
HY-P80541 AMPK alpha Antibody WB, IP Human
HY-P80791 Phospho-AMPK alpha 2 (Thr172) Antibody WB Human, Mouse, Rat

关联疾病

疾病名称 别名
Peutz-Jeghers Syndrome

PJS

Polyposis, Hamartomatous Intestinal

Polyps-And-Spots Syndrome

Lentiginosis, Perioral

Periorificial Lentiginosis Syndrome

Hamartomatous Intestinal Polyposis

Hamartomatous Polyp

Colonic Hamartomatous Polyp

Gastric Peutz-Jeghers Polyp

Peutz Jeghers Colon Polyp

Peutz Jeghers Polyp

Peutz-Jeghers Polyp Of Small Intestine

Peutz-Jeghers Small Bowel Hamartoma

Peutz Jeghers Polyposis

Intestinal Polyposis-Cutaneous Pigmentation Syndrome

Peutz-Jeghers Polyposis

Polyposis, Intestinal, Ii

Intestinal Hamartomatous Polyposis

Peutz-Jeghers Polyp

Peutz-Jeghers Polyp Of The Stomach

Peutz Jehgers Polyp

Peutz-Jeghers Polyps Of Small Bowel

Ischemia

Acute Coronary Syndrome

Wolff-Parkinson-White Syndrome

Wolff-Parkinson-White Pattern

Wpw Syndrome

Anomalous Atrioventricular Excitation

Anomalous A-V Excitation

Ventricular Pre-Excitation With Arrhythmia

WPWS

Ventricular Familial Preexcitation Syndrome

Preexcitation Syndrome

Ventricular Preexcitation

Wpw - [Wolff-Parkinson- White] Syndrome

Pre-Excitation Syndrome

Tuberous Sclerosis

Tuberous Sclerosis Syndrome

Bourneville'S Disease

Epiloia

Cerebral Sclerosis

Tuberose Sclerosis

Tuberous Sclerosis 1

Bourneville Disease

Bourneville Phakomatosis

Pringle'S Disease

Hyperglycemia
Type 2 Diabetes Mellitus

Insulin Resistance

NIDDM

Type 2 Diabetes

Diabetes Mellitus, Non-Insulin-Dependent

T2D

Noninsulin-Dependent Diabetes Mellitus

Diabetes Mellitus, Type Ii

Maturity-Onset Diabetes

Insulin Resistance, Severe, Digenic

Diabetes Mellitus, Type 2

Diabetes Mellitus, Noninsulin-Dependent

Diabetes Mellitus, Noninsulin-Dependent, Association With

Diabetes Mellitus, Noninsulin-Dependent, Late Onset

Hypertension, Insulin Resistance-Related, Susceptibility To

Insulin Resistance, Susceptibility To

Non-Insulin-Dependent Diabetes Mellitus

Type Ii Diabetes Mellitus

Adult-Onset Diabetes Mellitus

Maturity-Onset Diabetes Mellitus

Diabetes Mellitus Type 2

Type Ii Diabetes

Type 2 Diabetes Mellitus, Susceptibility To

Diabetes, Type 2

Diabetes Mellitus, Noninsulin-Dependent, Susceptibility To

Diabetes Mellitus, Non-Insulin-Dependent, Susceptibility To

Diabetes Mellitus, Type 2, Susceptibility To

Diabetes Mellitus, Noninsulin-Dependent, 2

Diabetes Mellitus, Type Ii, Susceptibility To

Hypertension, Insulin Resistance-Related

Adult-Onset Diabetes

Aodm

Diabetes Mellitus, Adult-Onset

Diabetes Mellitus Type Ii

Diabetes Mellitus Type 2, Susceptibility To

Diabetes, Type Ii, Susceptibility To

Diabetes Type 2

Diabetes Mellitus

Adult Onset Diabetes

Maturity Onset Diabetes

Nonketotic Diabetes

Non-Insulin Dependent Diabetes Mellitus

T2dm - [Type 2 Diabetes Mellitus]

Niddm - [Non Insulin Dependent Diabetes Mellitus]

Dm2

Dm Type Ii

Diabetic Type 2

Insulin Requiring Type 2 Diabetes

Noninsulin Dependent Diabetes

Non-Insulin-Dependent Diabetes Mellitus Without Complications

Diabetes Due To Insulin Secretory Defect

Diabetes Mellitus Due To Insulin Secretory Defect

Non-Insulin-Dependent Diabetes Of The Young

Senile Diabetes

Nonketotic Hyperglycaemia

Stable Diabetes

Glycogen Storage Disease

Glycogenosis

Glycogenoses

Gsd

Storage Disease, Glycogen

Gsd - [Glycogen Storage Disease]

Glycogen Thesaurismosis

Diffuse Glycogenosis

Generalised Glycogen Storage Disease

Generalised Glycogenosis

Generalised Glycogen Storage Disease Of Infants

Glycogen Synthase Deficiency

Ichthyosis, Congenital, Autosomal Recessive 3

Autosomal Recessive Congenital Ichthyosis 3

ARCI3

Lamellar Ichthyosis 5

Collodion Baby, Self-Healing

Ichthyosis, Lamellar, 5, Formerly

Li5, Formerly

Li5

Self-Healing Collodion Baby

Ichthyosis, Congenital, Autosomal Recessive, Type 3

Body Mass Index Quantitative Trait Locus 11

OBESITY

Obesity, Susceptibility To

Leanness, Inherited

Obesity, Susceptibility To, Bmiq11

Obesity, Mild, Early-Onset

Obesity, Association With

Obesity, Early-Onset, Susceptibility To

Obesity, Severe

Obesity, Severe, And Type Ii Diabetes

Obesity, Late-Onset

Obesity , Susceptibility To

BMIQ11

Obesity Bmiq11

Obesity, Early-Onset

Simple Obesity Nos

Excess Fat

Obesity, Not Elsewhere Classified, Body Mass Index Not Elsewhere Classified

Adiposis

Hypertrophic Cardiomyopathy

Hypertrophic Obstructive Cardiomyopathy

Cardiomyopathy, Hypertrophic

Cardiomyopathy Hypertrophic Obstructive

Cardiomyopathy, Hypertrophic, Familial

Idiopathic Myocardial Hypertrophy

Idiopathic Hypertrophic Cardiomyopathy

Obstructive Idiopathic Hypertrophic Cardiomyopathy

Obstructive Cardiomyopathy

Idiopathic Hypertrophic Subaortic Stenosis

Muscular Subaortic Stenosis

Hypertrophic Obstructive Subaortic Stenosis

Diabetes Mellitus

Diabetes

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus PRKAA2 RGD RGD:620893
Macaca mulatta PRKAA2 VGNC VGNC:76400
Canis familiaris PRKAA2 VGNC VGNC:53435
Bos taurus PRKAA2 VGNC VGNC:50249
Mus musculus PRKAA2 MGD MGI:1336173
Felis catus PRKAA2 VGNC VGNC:69046
Others PRKAA2 NCBI