1. Gene
  2. CDK1 - cyclin dependent kinase 1 Gene

CDK1 - cyclin dependent kinase 1 Gene

中文名称:细胞周期蛋白依赖性激酶 1

种属: Homo sapiens

同用名: CDC2; CDC28A; P34CDC2

基因 ID: 983 | 基因类型: protein coding

关于 CDK1

Cytogenetic location: 10q21.2 Genomic coordinates (GRCh38): 10:60,778,331-60,794,852 (from NCBI)

This gene has 8 transcripts (splice variants), 246 orthologues and 26 paralogues. Broad expression in lymph node (RPKM 12.8), bone marrow (RPKM 12.8) and 18 other tissues.

功能概要

该基因编码的蛋白质是 Ser/Thr 蛋白激酶家族的成员。这种蛋白质是称为 M 期促进因子 (MPF) 的高度保守的蛋白激酶复合物的催化亚基,它对于真核细胞周期的 G1/S 和 G2/M 相转变至关重要。有丝分裂细胞周期蛋白稳定地与这种蛋白质结合并作为调节亚基发挥作用。该蛋白的激酶活性受细胞周期中细胞周期蛋白积累和破坏的控制。该蛋白的磷酸化和去磷酸化在细胞周期控制中也起着重要的调节作用。已发现该基因编码不同亚型的可变剪接转录物变体。[RefSeq 提供,2009 年 3 月]

The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle. Mitotic cyclins stably associate with this protein and function as regulatory subunits. The kinase activity of this protein is controlled by cyclin accumulation and destruction through the cell cycle. The phosphorylation and dephosphorylation of this protein also play important regulatory roles in cell cycle control. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]

CDK1 基因产物(7)

mRNA Protein Name
NM_001786.5 NP_001777.1 cyclin-dependent kinase 1 isoform 1
XM_005270303.4 XP_005270360.1 cyclin-dependent kinase 1 isoform X1
NM_001170406.1 NP_001163877.1 cyclin-dependent kinase 1 isoform 4
NM_001320918.1 NP_001307847.1 cyclin-dependent kinase 1 isoform 1
NM_001170407.2 NP_001163878.1 cyclin-dependent kinase 1 isoform 4
NM_001130829.1
NM_033379.5 NP_203698.1 cyclin-dependent kinase 1 isoform 2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables RNA polymerase II CTD heptapeptide repeat kinase activity IDA
IDA: 通过直接分析推断
12721286 GOA
enables cyclin binding IDA
IDA: 通过直接分析推断
7739547 GOA
enables cyclin binding IPI
IPI: 通过物理相互作用推断
1312467 GOA
enables cyclin-dependent protein kinase activity IDA
IDA: 通过直接分析推断
1312467 GOA
enables cyclin-dependent protein serine/threonine kinase activity IDA
IDA: 通过直接分析推断
2188730 GOA
enables cyclin-dependent protein serine/threonine kinase activity IMP
IMP: 通过突变表型推断
24746669 GOA
enables histone kinase activity IDA
IDA: 通过直接分析推断
21871177 GOA
enables kinase activity IDA
IDA: 通过直接分析推断
28575661 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
7815540 GOA
enables protein kinase activity IDA
IDA: 通过直接分析推断
22854038 GOA
enables protein serine/threonine kinase activity IDA
IDA: 通过直接分析推断
7588608 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in DNA damage response IDA
IDA: 通过直接分析推断
19202191 GOA
involved in G2/M transition of mitotic cell cycle IDA
IDA: 通过直接分析推断
2188730 GOA
involved in epithelial cell differentiation IEP
IEP: 通过表达模式推断
21492153 GOA
involved in microtubule cytoskeleton organization involved in mitosis IDA
IDA: 通过直接分析推断
10791892 GOA
involved in mitotic nuclear membrane disassembly IDA
IDA: 通过直接分析推断
2188730 GOA
involved in negative regulation of apoptotic process IDA
IDA: 通过直接分析推断
11069302 GOA
involved in peptidyl-serine phosphorylation IDA
IDA: 通过直接分析推断
11298763 GOA
involved in peptidyl-threonine phosphorylation IDA
IDA: 通过直接分析推断
11298763 GOA
involved in peptidyl-threonine phosphorylation IMP
IMP: 通过突变表型推断
27238018 GOA
involved in positive regulation of G2/M transition of mitotic cell cycle IMP
IMP: 通过突变表型推断
24746669 GOA
involved in positive regulation of mitochondrial ATP synthesis coupled electron transport IMP
IMP: 通过突变表型推断
24746669 GOA
involved in positive regulation of mitotic sister chromatid segregation IDA
IDA: 通过直接分析推断
26829474 GOA
involved in positive regulation of protein localization to nucleus IMP
IMP: 通过突变表型推断
21871177 GOA
involved in protein localization to kinetochore IDA
IDA: 通过直接分析推断
18195732 GOA
involved in protein localization to kinetochore IMP
IMP: 通过突变表型推断
28479321 GOA
involved in regulation of attachment of mitotic spindle microtubules to kinetochore IDA
IDA: 通过直接分析推断
28479321 GOA
involved in regulation of circadian rhythm IMP
IMP: 通过突变表型推断
27238018 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in centrosome IDA
IDA: 通过直接分析推断
17488717 GOA
part of cyclin B1-CDK1 complex IMP
IMP: 通过突变表型推断
24746669 GOA
part of cyclin B1-CDK1 complex IPI
IPI: 通过物理相互作用推断
17495531 GOA
part of cyclin-dependent protein kinase holoenzyme complex IDA
IDA: 通过直接分析推断
1312467 GOA
located in cytoplasm IDA
IDA: 通过直接分析推断
15767402 GOA
located in midbody IDA
IDA: 通过直接分析推断
11069302 GOA
colocalizes with mitochondrial matrix IDA
IDA: 通过直接分析推断
24746669 GOA
located in mitotic spindle IDA
IDA: 通过直接分析推断
17488717 GOA
located in nucleus IDA
IDA: 通过直接分析推断
15767402 GOA
located in spindle microtubule IDA
IDA: 通过直接分析推断
11069302 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

CDK1 蛋白结构

Pkinase

Pkinase: Protein kinase domain (4 - 287)

  • 0
  • 100
  • 200
  • 297 a.a.
蛋白主名 其他名称

cyclin-dependent kinase 1

cell cycle controller CDC2

cell division control protein 2 homolog

cell division cycle 2, G1 to S and G2 to M

cell division protein kinase 1

p34 protein kinase

CDK1 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
CDK1 P06493 FOXO1 Homo sapiens Q12778
Anti Tag CoIP
18408765
种属内
CDK1 P06493 FOXO1 Homo sapiens Q12778
Protein Kinase Assay
18408765
种属内
CDK1 P06493 DEDD Homo sapiens O75618-1
Anti Bait CoIP
17283331
种属内
CDK1 P06493 DEDD Homo sapiens O75618-1
Anti Tag CoIP
17283331
种属内
CDK1 P06493 UBC Homo sapiens P0CG48
Anti Tag CoIP
20395957
种属内
CDK1 P06493 ALYREF Homo sapiens Q86V81
Crosslink
29128334
种属内
CDK1 P06493 CDKN1A Homo sapiens P38936
Anti Tag CoIP
33961781
种属内
CDK1 P06493 CDKN1A Homo sapiens P38936
TAP
23602568
种属内
CDK1 P06493 CDKN1A Homo sapiens P38936
Anti Tag CoIP
28514442
种属内
CDK1 P06493 CDKN1A Homo sapiens P38936
Pull Down
32707033
种属内
CDK1 P06493 CDKN1A Homo sapiens P38936
Anti Tag CoIP
23543736
种属内
CDK1 P06493 LATS1 Homo sapiens O95835
CoIP
9988268
种属内
CDK1 P06493 CKS1B Homo sapiens P61024
Anti Tag CoIP
25852190
种属内
CDK1 P06493 CKS1B Homo sapiens P61024
Anti Tag CoIP
33961781
种属内
CDK1 P06493 CKS1B Homo sapiens P61024
TAP
23602568
种属内
CDK1 P06493 CKS1B Homo sapiens P61024
MAPPIT
25416956
种属内
CDK1 P06493 CKS1B Homo sapiens P61024
Validated Y2H
25416956
种属内
CDK1 P06493 CKS1B Homo sapiens P61024
Anti Tag CoIP
26496610
种属内
CDK1 P06493 CKS1B Homo sapiens P61024
Y2H Prey Pooling
25416956
种属内
CDK1 P06493 CKS1B Homo sapiens P61024
Y2H Array
25416956
种属内
CDK1 P06493 CKS1B Homo sapiens P61024
Pull Down
32707033
种属内
CDK1 P06493 PKMYT1 Homo sapiens Q99640
Anti Tag CoIP
33961781
种属内
CDK1 P06493 PKMYT1 Homo sapiens Q99640
Anti Tag CoIP
28514442
种属内
CDK1 P06493 PKMYT1 Homo sapiens Q99640
Anti Tag CoIP
25852190
种属内
CDK1 P06493 PKMYT1 Homo sapiens Q99640
Protein Kinase Assay
10373560
种属内
CDK1 P06493 PKMYT1 Homo sapiens Q99640
TAP
23602568
种属内
CDK1 P06493 PKMYT1 Homo sapiens Q99640
Pull Down
32707033
种属内
CDK1 P06493 CCNB1 Homo sapiens P14635
Protein Kinase Assay
12612082
种属内
CDK1 P06493 CCNB1 Homo sapiens P14635
Protein Kinase Assay
19879842
种属内
CDK1 P06493 CCNB1 Homo sapiens P14635
Pull Down
32707033
种属内
CDK1 P06493 CCNB1 Homo sapiens P14635
Anti Bait CoIP
17283331
种属内
CDK1 P06493 CCNB1 Homo sapiens P14635
Anti Tag CoIP
17283331
种属内
CDK1 P06493 CCNB1 Homo sapiens P14635
Protein Kinase Assay
18408765
种属内
CDK1 P06493 CCNB1 Homo sapiens P14635
Anti Bait CoIP
23799914
种属内
CDK1 P06493 CCNB1 Homo sapiens P14635
Anti Tag CoIP
26496610
种属内
CDK1 P06493 CCNB1 Homo sapiens P14635
Anti Tag CoIP
25852190
种属内
CDK1 P06493 CCNB1 Homo sapiens P14635
Protein Kinase Assay
33037310
种属内
CDK1 P06493 CCNB1 Homo sapiens P14635
TAP
23602568
种属内
CDK1 P06493 CCNB1 Homo sapiens P14635
Anti Tag CoIP
28514442
种属内
CDK1 P06493 BIRC5 Homo sapiens O15392
IF
17681274
种属内
CDK1 P06493 CDKN1B Homo sapiens P46527
Anti Tag CoIP
28514442
种属内
CDK1 P06493 CDKN1B Homo sapiens P46527
Anti Tag CoIP
23543736
种属内
CDK1 P06493 CDKN1B Homo sapiens P46527
Anti Bait CoIP
24358021
种属内
CDK1 P06493 CDKN1B Homo sapiens P46527
Pull Down
32707033
种属内
CDK1 P06493 CDKN1B Homo sapiens P46527
Anti Tag CoIP
33961781
种属内
CDK1 P06493 CDKN1B Homo sapiens P46527
TAP
23602568
种属间
CDK1 P06493 lt_sv40 Simian virus 40 P03070
Pull Down
7815540
种属内
CDK1 P06493 EIF2AK2 Homo sapiens P19525
Protein Kinase Assay
20395957
种属内
CDK1 P06493 TNFSF12 Homo sapiens O43508
Y2H Array
32814053
种属内
CDK1 P06493 TNFSF12 Homo sapiens O43508
Validated Y2H
32814053
种属内
CDK1 P06493 TNFSF12 Homo sapiens O43508
Y2H Pooling
32814053
种属内
CDK1 P06493 CDC25C Homo sapiens P30307
Anti Tag CoIP
17349584
种属间: 跨种属相互作用 种属内: 同种属相互作用

重组 CDK1 蛋白

目录号 产品名 蛋白编号 纯度
HY-P74257 CDK1-CCNE1 Heterodimer Protein, Human (sf9, His-GST) NP_001777.1 (M1-M297)& NP_001229.1 (M1-A410) ≥95%
HY-P75668 CDK1 Protein, Human (sf9, GST) P06493 (M1-M297) ≥95%

关联疾病

疾病名称 别名
Colorectal Cancer

Colon Cancer

Colorectal Carcinoma

Colon Carcinoma

Colorectal Cancer, Susceptibility To

Carcinoma Of Colon

CRC

Colorectal Cancer With Chromosomal Instability, Somatic

Colon Cancer, Somatic

Colon Cancer, Susceptibility To

Colonic Neoplasms

Colorectal Neoplasms

Colorectal Cancer, Somatic

Colon Cancer, Advanced, Somatic

Colonic Carcinoma

Colorectal Carcinomas

Colon Cancers

Colorectal Cancers

Cancer, Colorectal, Somatic

Cancer, Colon

Cancer, Colorectal, Susceptibility To

Colorectal Neoplasm

Colonic Neoplasm

Malignant Tumor Of Colon

Hepatocellular Carcinoma

Liver Cancer

Primary Liver Cancer

HCC

Hepatoma

Malignant Neoplasm Of Liver

Liver Neoplasms

Cancer, Hepatocellular

Liver Cell Carcinoma

Lcc

Hepatoblastoma, Somatic

Hepatic Cancer

Primary Malignant Neoplasm Of Liver

Rare Tumor Of Liver And Intrahepatic Biliary Tract

Hepatocellular Carcinoma, Somatic

Hepatocellular Carcinoma, Childhood Type, Somatic

Hepatocellular Cancer, Somatic

Ca Liver - Primary

Hepatic Neoplasm

Malignant Hepato-Biliary Neoplasm

Malignant Neoplasm Of Liver, Not Specified As Primary Or Secondary

Malignant Neoplasm Of Liver, Primary

Malignant Tumor Of Liver

Neoplasm Of Liver

Non-Resectable Primary Hepatic Malignant Neoplasm

Resectable Malignant Neoplasm Of Liver

Resectable Malignant Neoplasm Of The Liver

Primary Liver Carcinoma

Primary Malignant Liver Neoplasm

Primary Cancer Of Liver

Primary Tumor Of The Liver

Rare Tumor Of Liver And Ibt

Hepatocellular Cancer

Neoplasm Of The Liver

Hepatomas

Liver Neoplasm

Liver Carcinoma

Liver And Intrahepatic Biliary Tract Carcinoma

Malignant Hepatobiliary Neoplasm

Adult Primary Hepatocellular Carcinoma

Hepatoblastoma

Carcinoma Of Liver

Malignant Liver Tumour

Malignant Hepatic Tumour

Thrombocytopenia

Low Platelet Count

Low Platelets

Decreased Platelets

Platelet Dysfunction Nos

Peripheral Nervous System Disease

Peripheral Neuropathy

Peripheral Nerve Disease

Peripheral Nerve Disorders

Neuropathy, Peripheral

Peripheral Neuropathy Due To Vitamin Pyridoxine Hyperalimentation

Nervous System Disease

Abnormality Of The Nervous System

Nervous System Diseases

Nervous System Disorder

Neuroblastoma

Nb

Neuroblastoma, Susceptibility To

Neuroblastomas

Central Neuroblastoma

Squamous Cell Carcinoma, Head And Neck

Squamous Cell Carcinoma Of The Head And Neck

HNSCC

Head And Neck Squamous Cell Carcinoma

Head And Neck Cancer

Squamous Cell Carcinoma Of Lip

Squamous Cell Carcinoma, Head And Neck, Somatic

Carcinoma Of The Head And Neck

Squamous Cell Carcinomas Of Head And Neck

Scchn

Squamous Cell Carcinoma Of The Hypopharynx

Squamous Cell Carcinoma Of The Oropharynx

Squamous Cell Carcinoma Of Salivary Glands

Squamous Cell Carcinoma Of The Nasal Cavity And Paranasal Sinuses

Squamous Cell Carcinoma Of The Nasal Cavity And Sinuses

Squamous Cell Carcinoma Of The Oral Cavity

Squamous Cell Carcinoma Of The Lip

Carcinoma, Squamous Cell Of Head And Neck

Lip Squamous Cell Carcinoma

Cancer, Head/Neck

Carcinoma, Squamous Cell, Head And Neck

Salivary Gland Squamous Cell Carcinoma

Cancer Of Head And Neck

Squamous Cell Carcinoma Of Oropharynx Nos

Prostate Cancer

Prostate Carcinoma

Prostate Cancer, Familial

Prostate Neoplasm

Prostate Cancer, Somatic

Prostate Cancer, Susceptibility To

Prostatic Cancer

Prostatic Neoplasms

Hereditary Prostate Cancer

Prostatic Neoplasm

Cancer Of Prostate

Carcinoma Of Prostate

Familial Prostate Cancer

Familial Prostate Carcinoma

Malignant Tumor Of Prostate

Malignant Neoplasm Of Prostate

Prostate Cancer, Familial, Susceptibility To

Malignant Tumor Of The Prostate

Ngp - New Growth Of Prostate

Tumor Of The Prostate

Prostate Cancer, Hereditary

Cancer Of The Prostate

Malignant Neoplasm Of The Prostate

Prostatic Carcinoma

PC

Prca

Cancer, Prostate

Malignant Prostatic Tumour

Malignant Tumour Of Prostate

Primary Prostate Cancer

Primary Malignant Neoplasm Of Prostate

Prostate Gland Cancer

Bladder Cancer

Urinary Bladder Cancer

Bladder Carcinoma

Urinary Bladder Carcinoma

Bladder Neoplasm

Bladder Tumor

Cancer, Bladder

Malignant Neoplasm Of Urinary Bladder

Carcinoma Of Bladder

Bladder Cancer, Somatic

Tumor Of The Bladder

Carcinoma Of Urinary Bladder

Bladder Carcinoma Urinary

Cancer Of The Urinary Bladder

Cancer, Urinary Bladder

Malignant Bladder Neoplasm

Malignant Bladder Tumor

Neoplasm Of The Bladder

Neoplasm Of The Urinary Bladder

Tumor Of The Urinary Bladder

Urinary Bladder Neoplasm

BLC

Urothelial Carcinoma Of The Bladder

Bladder Tumors

Urinary Bladder Neoplasms

Bladder Cancer Nos

Vesical Cancer Nos

Malignant Neoplasm Of Bladder, Part Unspecified

Malignant Tumour Of Urinary Bladder

Primary Malignant Neoplasm Of Bladder

Gallbladder Cancer

Gallbladder Carcinoma

Gallbladder Neoplasm

Malignant Neoplasm Of Gallbladder

Malignant Tumour Of Gallbladder

Gallbladder Ca

Localized Malignant Gallbladder Neoplasm

Malignant Tumor Of The Gallbladder

Tumor Of The Gallbladder

Cancer Of The Gallbladder

Carcinoma Gallbladder

Carcinoma Of Gallbladder

Gallbladder Neoplasms

Malignant Neoplasm Of Gallbladder Localized

Cancer Of Gallbladder

Primary Malignant Neoplasm Of Gallbladder

Leukemia, Acute Lymphoblastic

Acute Lymphoblastic Leukemia

ALL

Acute Lymphocytic Leukemia

Leukemia, Acute Lymphocytic, Susceptibility To, 1

Acute Lymphoblastic Leukaemia

Precursor Lymphoblastic Lymphoma/Leukemia

Precursor Lymphoid Neoplasm

Leukemia, Acute Lymphoblastic, Susceptibility To

B-Cell Acute Lymphoblastic Leukemia

Leukemia, Acute Lymphocytic 1

Acute Lymphocytic Leukaemia

Acute Lymphoblastic Leukemia/Lymphoma

All1

Childhood Acute Lymphoblastic Leukemia

Leukemia Acute Lymphoblastic 1

Leukemia Acute Lymphoblastic B-Hyperdiploid

Leukemia Acute Lymphocytic

Leukemia Acute Lymphocytic 1

Leukemia B-Cell Acute Lymphoblastic

Leukemia T-Cell Acute Lymphoblastic

Leukemia, Acute Lymphoblastic, 3

ALL3

Lymphoblastic Leukemia Acute

Leukemia, Acute, Lymphoblastic

Precursor Cell Lymphoblastic Leukemia Lymphoma

Leukemia, Lymphocytic, Acute, L1

Leukemia, Acute Lymphoblastic, Susceptibility To, 3

Ovarian Cancer

Ovarian Carcinoma

Ovarian Neoplasm

Malignant Tumour Of Ovary

Epithelial Ovarian Cancer

Neoplasm Of Ovary

Ovarian Neoplasms

Ovarian Cancers

Malignant Neoplasm Of Ovary

Primary Malignant Neoplasm Of Ovary

Ovarian Cancer, Somatic

Malignant Ovarian Tumor

Ovary Neoplasm

Primary Ovarian Cancer

Tumor Of The Ovary

Cancer Of The Ovary

Malignant Neoplasm Of The Ovary

Malignant Tumor Of The Ovary

Ovarian Malignant Tumor

OC

Ovarian Carcinomas

Cancer, Ovarian

Cancer Of Ovary

Ovary Cancer

Ca Ovary

Lymphoma, Non-Hodgkin, Familial

Non-Hodgkin Lymphoma

Lymphoma, Non-Hodgkin

NHL

Lymphoma, Non-Hodgkin, Somatic

Lymphoma, Follicular, Somatic

Familial Non-Hodgkin Lymphoma

Lymphoma Non-Hodgkins

Follicular Lymphoma, Somatic

Lymphosarcoma

Non-Hodgkins Lymphoma

Leukemia, Chronic Lymphocytic

Chronic Lymphocytic Leukemia

B-Cell Chronic Lymphocytic Leukemia

CLL

B-Cell Chronic Lymphoid Leukemia

Chronic Lymphatic Leukemia

Chronic Lymphocytic Leukaemia

Lymphoplasmacytic Leukemia

Small Lymphocytic Lymphoma

Leukemia, Chronic Lymphatic

B-Cell Chronic Lymphocytic Leukaemia

Chronic Lymphatic Leukaemia

Lymphoplasmacytic Leukaemia

B Cell Chronic Lymphocytic Leukemia

Chronic B-Cell Lymphocytic Leukemia

Leukemia, Lymphocytic, Chronic

B-Cll

Chronic Lymphoid Leukemia

Leukemia Lymphocytic Chronic

Lymphoma Small Lymphocytic

Leukemia, Lymphocytic, Chronic, B-Cell

Fanconi Anemia, Complementation Group A

Fanconi Anemia

Fanconi Pancytopenia

Fanconi Anemia Complementation Group A

FANCA

Fa

Fanconi Panmyelopathy

Fanconi'S Anemia

Fanconi Anaemia

Fanconi'S Anaemia

Fanconi Hypoplastic Anemia

Estren-Dameshek Variant Of Fanconi Anemia

Estren-Dameshek Variant Of Fanconi Pancytopenia

Fanconi Anemia Estren-Dameshek Variant

Fanconis Anemia

Congenital Nervous System Abnormality

Congenital Neurologic Anomaly

Congenital Nervous System Disorder

Leukemia, Acute Myeloid

Acute Myeloid Leukemia

Leukemia, Acute Myelogenous

Acute Myelogenous Leukemia

AML

Leukemia, Acute Myeloid, Susceptibility To

Acute Myeloblastic Leukemia

Leukemia, Acute Myeloid, Reduced Survival In, Somatic

Acute Myeloid Leukaemia

Leukemia, Myelocytic, Acute

Therapy Related Acute Myeloid Leukemia And Myelodysplastic Syndrome

Secondary Aml

Acute Myelocytic Leukemia

Leukemia, Myeloid, Acute

Acute Myeloid Leukemia, Somatic

Leukemia, Acute Myeloid, Somatic

Myeloid Leukemia, Acute, M4/M4eo Subtype, Somatic

Acute Myeloblastic Leukaemia

Acute Myelogenous Leukaemia

Aml - Acute Myeloid Leukemia

Acute Myeloid Leukemia With Cebpa Somatic Mutations

Aml With Cebpa Somatic Mutations

Inherited Acute Myeloid Leukemia

Familial Aml

Inherited Aml

Pure Familial Aml

Pure Familial Acute Myeloid Leukemia

Secondary Acute Myeloid Leukemia

Therapy-Related Aml And Myelodysplastic Syndrome

Acute Myeloid Leukemia, Secondary

Acute Non-Lymphoblastic Leukemia

Acute Non-Lymphocytic Leukemia

Acute Biphenotypic Leukemia

Acute Undifferentiated Leukemia

Acute Myeloblastic Leukaemia With Multilineage Dysplasia

Acute Myeloid Leukaemia With Multilineage Dysplasia Without Mention Of Remission

Acute Myeloid Leukaemia With Myelodysplasia-Related Features

Retinal Cancer

Malignant Neoplasm Of Retina

Retinal Neoplasms

Malignant Retinal Neoplasm

Malignant Tumor Of Retina

Neoplasm Of Retina

Retinal Tumor

Retinal Neoplasm

Cancer Of The Retina

Malignant Retinal Tumour

Malignant Tumour Of Retina

Primary Malignant Neoplasm Of Retina

Seckel Syndrome 4

SCKL4

Seckel Syndrome, Type 4

Ataxia-Telangiectasia

Ataxia Telangiectasia

Louis-Bar Syndrome

AT

At1

Ataxia-Telangiectasia Syndrome

Ataxia - Telangiectasia Variant

Boder-Sedgwick Syndrome

Louis Bar Syndrome

Cerebello-Oculocutaneous Telangiectasia

Immunodeficiency With Ataxia Telangiectasia

A-T

Ataxia Telangiectasia Syndrome

Atm

Telangiectasia, Cerebello-Oculocutaneous

Ataxia-Telangiectasia Variant

Frontotemporal Dementia

Pallidopontonigral Degeneration

Frontotemporal Lobar Degeneration

Semantic Dementia

FTD

Frontotemporal Lobe Dementia

Multiple System Tauopathy With Presenile Dementia

Dementia, Frontotemporal

Frontotemporal Dementia With Parkinsonism

Mstd

Frontotemporal Lobar Degeneration With Tau Inclusions

Ftld With Tau Inclusions

Dementia, Frontotemporal, With Parkinsonism

Fldem

Ftdp17

Disinhibition-Dementia-Parkinsonism-Amyotrophy Complex

Ddpac

Wilhelmsen-Lynch Disease

Wld

Ppnd

Dementia, Frontotemporal, With Or Without Parkinsonism

Semantic Primary Progressive Aphasia

Semantic Variant Ppa

Wilhemsen-Lynch Disease

Frontotemporal Dementia-Amyotrophic Lateral Sclerosis

Frontotemporal Dementia And Parkinsonism Linked To Chromosome 17

Ftd-Als

Ftld

Pick Complex

Pick Disease Of The Brain

Frontotemporal Dementia With Parkinsonism-17

Grn-Related Frontotemporal Dementia

Frontotemporal Dementia With Motor Neuron Disease

Dementia In Fronto-Temporal Lobar Degeneration

Ftd - [Frontotemporal Dementia]

Temple Dementia

Frontal Lobe Dementia

Eye Disease

Eye Diseases

Abnormality Of The Eye

Toxoplasma Oculopathy

Lung Cancer

Lung Carcinoma

Non-Small Cell Lung Carcinoma

Lung Cancer, Protection Against

Lung Cancer, Susceptibility To

Adenocarcinoma Of Lung, Somatic

Nonsmall Cell Lung Cancer

Adenocarcinoma Of Lung, Response To Tyrosine Kinase Inhibitor In

Lung Neoplasm

Carcinoma Of Lung

Lung Non-Small Cell Carcinoma

Non-Small Cell Lung Cancer

Nsclc

Lung Neoplasms

Malignant Neoplasm Of Lung

Alveolar Cell Carcinoma

Nonsmall Cell Lung Cancer, Somatic

Nonsmall Cell Lung Cancer, Response To Tyrosine Kinase Inhibitor In

Nonsmall Cell Lung Cancer, Susceptibility To

Lung Cancer, Somatic

Lung Cancer, Resistance To

Cancer Of Lung

Cancer Of Bronchus

Cancer Of The Lung

Lung Malignancies

Lung Malignant Tumors

Malignant Lung Tumor

Malignant Tumor Of Lung

Pulmonary Cancer

Pulmonary Carcinoma

Pulmonary Neoplasms

Respiratory Carcinoma

LNCR

Adenocarcinoma Of Lung

Neoplasm Of Lung

Cancer Lung

Carcinoma Non-Small Cell Lung

Carcinoma, Non-Small-Cell Lung

Lung Cancers

Lung Carcinomas

Cancer, Lung

Cancer, Lung, Non-Small Cell

Primary Malignant Neoplasm Of Lung

Bronchioloalveolar Adenocarcinoma

Bone Cancer

Malignant Bone Neoplasm

Bone Carcinoma

Bone Neoplasms

Bone Neoplasm

Bone Tumour

Ca - Bone Cancer

Malignant Bone Tumour

Malignant Neoplasm Of Bone

Malignant Osseous Tumor

Neoplasm Of Bone

Osseous Tumor

Osteosarcoma Of Bone

Osteogenic Neoplasm

Rhabdomyosarcoma
Primary Autosomal Recessive Microcephaly

Autosomal Recessive Primary Microcephaly

Mcph

True Microcephaly

Microcephalia Vera

Microcephaly Vera

Microcephaly Primary Hereditary

Microcephaly, Primary, Autosomal Recessive

Primary Microcephaly

Alzheimer Disease, Familial, 1

Alzheimer Disease

Alzheimer'S Disease

Presenile And Senile Dementia

AD1

Alzheimer Disease, Susceptibility To

Alzheimer Disease, Late-Onset, Susceptibility To

Alzheimer Disease 1, Familial

AD

Familial Alzheimer Disease

Alzheimer Disease, Late-Onset

Alzheimers Dementia

Alzheimer Dementia

Alzheimer Sclerosis

Alzheimer Syndrome

Alzheimer-Type Dementia

Dat

Primary Senile Degenerative Dementia

Sdat

Alzheimer Disease 1

Autosomal Dominant Alzheimer Disease

Early-Onset Alzheimer Disease With Cerebral Amyloid Angiopathy

Late Onset Alzheimer Disease

Alzheimers Disease

Alzheimer Disease, Early-Onset, With Cerebral Amyloid Angiopathy

Late-Onset Alzheimers Disease

Alzheimer'S Disease Pathway Kegg

Dementia Due To Alzheimer'S Disease

Alzheimer Disease Type 1

Alzheimers

Gastric Cancer

Stomach Cancer

Stomach Carcinoma

Gastric Carcinoma

Gastric Cancer, Somatic

Gastric Neoplasm

Carcinoma Of Stomach

Stomach Neoplasms

Malignant Neoplasm Of Stomach

Gastric Cancer Risk After H. Pylori Infection

Cancer Of The Stomach

Adult Stomach Cancer

Adult Stomach Carcinoma

GASC

Gastric Cancer Intestinal

Gastric Cancers

Gastric Carcinomas

Cancer, Gastric

Stomach Neoplasm

Malignant Neoplasm Of Body Of Stomach

Malignant Tumor Of Lesser Curve Of Stomach

Gastrocarcinoma Of Unspecified Site

Leather Bottle Stomach

Carcinoma Of Fundus Of Stomach

Cancer Of Fundus Of Stomach

Primary Malignant Neoplasm Of Body Of Stomach

Cancer Of Body Of Stomach

Primary Malignant Neoplasm Of Pyloric Antrum

Pyloric Antrum Cancer

Malignant Tumour Of Stomach

Cataract 36

CTRCT36

Catc4

Autosomal Recessive Congenital Cataract 4

Cataract, Autosomal Recessive Congenital 4

Cataract, Type 36

Autosomal Recessive Nonsyndromic Deafness 32

Deafness, Autosomal Recessive 32

Autosomal Recessive Deafness 105

Autosomal Recessive Deafness 32

Dfnb32

Hearing Impairment Infertile Male Syndrome

Hiims

Deafness, Autosomal Recessive, Type 32

Cockayne Syndrome

Cockayne'S Syndrome

Dwarfism-Retinal Atrophy-Deafness Syndrome

Neill-Dingwall Syndrome

Progeria-Like Syndrome

Progeroid Nanism

Cs

B-Cell Lymphoma

Lymphoma, B-Cell

B-Cell Lymphomas

B-Cell Lymphocytic Neoplasm

Lymphoma B-Cell

B-Cell Lymphoma Nos

Cornelia De Lange Syndrome

De Lange Syndrome

Brachmann De Lange Syndrome

Brachmann-De Lange Syndrome

Cdls

Bdls

Typus Degenerativus Amstelodamensis

Polyploidy

Polyploid

Polyploidy Syndrome

Retinoblastoma

RB

Trilateral Retinoblastoma

RB1

Retinoblastoma, Trilateral

Neuroblastoma Of Retina

Rb - Retinoblastoma

Eye Cancer, Retinoblastoma

Retinal Cancer

Retinal Tumor

Glioma, Retinal

Non-Hereditary Retinoblastoma

Childhood Cancer Retinoblastoma

Malignant Neoplasm Of Retina

Retinal Neoplasms

Breast Cancer

Breast Carcinoma

Breast Cancer, Familial

Malignant Neoplasm Of Breast

Male Breast Cancer

Breast Cancer, Susceptibility To

Breast Cancer, Early-Onset

Malignant Tumor Of Breast

Carcinoma Of Male Breast

Breast Cancer, Invasive Ductal

Breast Cancer, Protection Against

Breast Cancer, Somatic

Breast Cancer, Male

Breast Cancer, Lobular, Somatic

Breast Tumor

Mammary Cancer

Mammary Tumor

Malignant Neoplasm Of Male Breast

Mammary Carcinoma

Male Breast Carcinoma

Familial Cancer Of Breast

Invasive Ductal Breast Carcinoma

Breast Cancer Susceptibility

Breast Cancer, Male, Susceptibility To

Breast Cancer, Early-Onset, Susceptibility To

Malignant Tumor Of The Breast

Mammary Neoplasm

Primary Breast Cancer

Neoplasm Of Male Breast

Carcinoma Of Breast

Breast Cancer In Men

Familial Breast Cancer

Cancer Of Breast

BC

Breast Cancer Familial

Breast Cancer Familial Male

Breast Cancer, Familial Male

Breast Male Carcinoma

Breast Neoplasms

Breast Neoplasms, Male

Mammary Tumors

Mammary Carcinomas

Cancer, Breast

Cancer, Breast, Susceptibility

Invasive Breast Ductal Carcinoma

Breast Neoplasm

Susceptibility To Breast Cancer

Mammary Neoplasms

Animal Mammary Neoplasms

Primary Malignant Neoplasm Of Breast

Infiltrating Ductal Carcinoma Of Breast

Infiltrating Duct Carcinoma Of Unspecified Site

Infiltrating Ductular Carcinoma Of Unspecified Site

Invasive Breast Carcinoma Of No Special Type

Microinvasive Carcinoma Of Breast

Carcinoma With Apocrine Differentiation

Esophageal Cancer

Esophageal Carcinoma

Carcinoma Of Esophagus

Esophageal Squamous Cell Carcinoma, Somatic

Esophageal Carcinoma, Somatic

Esophagus Cancer

Gastric Cardia Adenocarcinoma

Esophageal Neoplasms

Esophageal Cancer, Somatic

Cancer Of Esophagus

Cancer Of Oesophagus

Carcinoma Of Oesophagus

Ca Lower Third Oesophagus

Ca Middle Third Oesophagus

Malignant Neoplasm Of Distal Third Of Esophagus

Malignant Neoplasm Of Lower Third Of Oesophagus

Malignant Neoplasm Of Middle Third Of Oesophagus

Malignant Neoplasm Of Proximal Third Of Esophagus

Malignant Neoplasm Of Upper Third Esophagus

Malignant Tumor Of Abdominal Esophagus

Malignant Tumor Of Distal Third Of Esophagus

Malignant Tumor Of Proximal Third Of Esophagus

Malignant Tumor Of The Middle Third Of The Esophagus

ESCR

Aerodigestive Tract Cancer

Escc

Esophageal Squamous Cell Carcinoma

Cancer, Esophageal

Malignant Neoplasm Of Esophagus

Squamous Cell Carcinoma Of Esophagus

Malignant Neoplasm Of Middle Third Of Esophagus

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Mus musculus CDK1 MGD MGI:88351
Rattus norvegicus CDK1 RGD RGD:2319
Felis catus CDK1 VGNC VGNC:97378
Canis familiaris CDK1 VGNC VGNC:39042
Bos taurus CDK1 VGNC VGNC:27115
Macaca mulatta CDK1 VGNC VGNC:100309
Others CDK1 NCBI