Alk - anaplastic lymphoma kinase Gene

中文名称：间变性淋巴瘤激酶

种属: Mus musculus

同用名: Tcrz; CD246

关于 Alk

功能概要

预测该基因编码的蛋白可实现相同的蛋白结合活性和跨膜受体蛋白酪氨酸激酶活性。参与能量稳态；脂质分解代谢过程的负调节；和树突发育的正调控。作用于多个过程的上游或内部，包括海马体发育；对环境富集的反应；和游泳行为。预测位于轴突；胞体；和质膜。预计是受体复合体的一部分。预计是质膜的组成部分。以多种结构表达，包括消化系统；泌尿生殖系统；外皮系统；神经系统;和感觉器官。与人类 ALK（ALK 受体酪氨酸激酶）同源。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable identical protein binding activity and transmembrane receptor protein tyrosine kinase activity. Involved in energy homeostasis; negative regulation of lipid catabolic process; and positive regulation of dendrite development. Acts upstream of or within several processes, including hippocampus development; response to environmental enrichment; and swimming behavior. Predicted to be located in axon; cell body; and plasma membrane. Predicted to be part of receptor complex. Predicted to be integral component of plasma membrane. Is expressed in several structures, including alimentary system; genitourinary system; integumental system; nervous system; and sensory organ. Orthologous to human ALK (ALK receptor tyrosine kinase). [provided by Alliance of Genome Resources, Apr 2022]