1. Gene
  2. C2 - complement component 2 (within H-2S) Gene

C2 - complement component 2 (within H-2S) Gene

种属: Mus musculus

基因 ID: 12263 | 基因类型: protein coding

关于 C2

功能概要

This gene encodes component C2 of the classical pathway of the Complement System. The encoded protein undergoes proteolytic processing mediated by component C1 resulting in C2a and C2b fragments. C2a fragment, in turn, selectively cleaves components C3 and C5 of the Complement System. Mice lacking the encoded protein are found to be more susceptible to Bacterial infections. Mutations in the human homolog of this gene are associated with disorders such as systemic lupus erythematosus, Henoch-Schonlein purpura, or polymyositis. [provided by RefSeq, Mar 2015]

C2 基因产物(1)

mRNA Protein Name
NM_013484.2 NP_038512.2 complement C2 preproprotein
蛋白主名 其他名称

complement C2

MHC complement component C2

classical-complement pathway C3/C5 convertase

complement component C2

complement factor C2

重组 C2 蛋白

目录号 产品名 蛋白编号 纯度
HY-P74374 C2/Complement C2 Protein, Mouse (HEK293, His) P21180-1 (A19-L760) ≥95%

直系同源

种属 基因名 来源 基因 ID
Homo sapiens C2 NCBI NCBI:717
Canis familiaris C2 NCBI NCBI:474853
Macaca fascicularis C2 NCBI NCBI:102137096
Rattus norvegicus C2 NCBI NCBI:24231
Macaca mulatta C2 NCBI NCBI:106997899