2. Gene
  3. HCCS - holocytochrome c synthase Gene

HCCS - holocytochrome c synthase Gene

  • 基因
  • 蛋白
  • 相关产品

种属: Homo sapiens (human)

同用名: MLS; CCHL; MCOPS7; LSDMCA1

基因 ID: 3052 | 基因类型: protein coding

关于 HCCS

功能概要

The protein encoded by this gene is an Enzyme that covalently links a heme group to the apoprotein of cytochrome c. Defects in this gene are a cause of microphthalmia syndromic type 7 (MCOPS7). Three transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jan 2010]

HCCS 基因产物(1)

mRNA Protein Name
NM_001122608.3 NP_001116080.1 holocytochrome c-type synthase
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables heme binding IDA
IDA: 通过直接分析推断
23150584 GOA
enables holocytochrome-c synthase activity IDA
IDA: 通过直接分析推断
23150584 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
28514442 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cytochrome c-heme linkage IDA
IDA: 通过直接分析推断
23150584 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in membrane IDA
IDA: 通过直接分析推断
23150584 GOA
located in mitochondrion IDA
IDA: 通过直接分析推断
11827457 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

holocytochrome c-type synthase

cytochrome c heme-lyase

cytochrome c-type heme lyase

holocytochrome-c synthetase

microphthalamia with linear skin defects

microphthalmia with linear skin defects

HCCS 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra HCCS P53701 AGK Homo sapiens Q53H12
Anti Tag CoIP
33961781
Intra HCCS P53701 AGK Homo sapiens Q53H12
Anti Tag CoIP
28514442
Intra HCCS P53701 SNX1 Homo sapiens Q13596
Validated Y2H
32296183
Intra HCCS P53701 CIDEB Homo sapiens Q9UHD4
Y2H Array
32296183
Intra HCCS P53701 CIDEB Homo sapiens Q9UHD4
Validated Y2H
32296183
Intra HCCS P53701 CIDEB Homo sapiens Q9UHD4
Y2H Prey Pooling
32296183
Intra HCCS P53701 SENP2 Homo sapiens Q9HC62
Validated Y2H
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

相关产品

Approval
生物活性分子 (20)
目录号 产品名 作用方式
纯度 是否罕见病
HY-50767 Palbociclib Inhibitor 99.94% 否
HY-17386 Rosiglitazone 99.94% 是
HY-15306 Eltrombopag 99.94% 是
HY-50767A Palbociclib monohydrochloride Inhibitor 99.98% 否
HY-A0065 Palbociclib isethionate Inhibitor 99.99% 否
HY-B0402 Amantadine 99.90% 是
HY-50767C Palbociclib hydrochloride Inhibitor 99.93% 否
HY-N7073 Silymarin Inhibitor ≥80.0% 否
HY-107193 Bacitracin Inhibitor / 是
HY-15306A Eltrombopag Olamine 99.96% 是
HY-B0402A Amantadine hydrochloride ≥98.0% 是
HY-100008 Peretinoin 99.79% 是
HY-17386A Rosiglitazone hydrochloride 99.31% 是
HY-N2591 Isocorydine 99.95% 否
HY-B0310 Nizatidine Antagonist 99.68% 否
HY-17386B Rosiglitazone potassium / 否
HY-50767B Palbociclib dihydrochloride Inhibitor / 否
HY-50767D Palbociclib orotate Inhibitor / 否
HY-B0402B Amantadine sulfate / 否
HY-N2591A Isocorydine hydrochloride / 否
抗体抑制剂 (1)
目录号 产品名 作用方式
纯度 是否罕见病
HY-P9971 Camrelizumab Inhibitor 98.80% 否
Clinical Phase
生物活性分子 (3)
目录号 产品名 作用方式
纯度 Phase
HY-18750 Zorifertinib 99.76% Phase 3
HY-100492 Fisogatinib Inhibitor 99.87% Phase 2
HY-116000 Glumetinib Inhibitor 99.92% Phase 2
抗体抑制剂 (3)
目录号 产品名 作用方式
纯度 Phase
HY-P99108 Penpulimab Inhibitor 98.80% Phase 4
HY-P99013 Codrituzumab Inhibitor 95.70% Phase 2
HY-P99353 Ascrinvacumab Inhibitor 97.45% Phase 2
Pre-clinical Phase
生物活性分子 (145)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-N2334 Glycochenodeoxycholic acid ≥98.0% 否
HY-16706A Remodelin hydrobromide Inhibitor 99.52% 否
HY-N0751 Scutellarin Inhibitor 98.56% 否
HY-131045 HADA hydrochloride 99.08% 否
HY-111226 GSK5182 99.85% 否
HY-116761 GSK467 Inhibitor 99.55% 否
HY-N2334A Glycochenodeoxycholic acid sodium salt 99.36% 否
HY-15897 LDN-212854 Inhibitor 99.70% 否
HY-15449 Kaempferide 99.35% 否
HY-N0220 Dauricine 99.91% 否
HY-N0070 Solasonine 99.19% 否
HY-W015309 Decanoic acid Inhibitor ≥98.0% 否
HY-113261 Oleoylcarnitine 99.82% 否
HY-111126 K67 Activator 98.43% 否
HY-12794 Vps34-PIK-III Inhibitor 99.63% 否
HY-123921 Gefitinib-based PROTAC 3 Inhibitor 99.98% 否
HY-N0876 Arenobufagin Inhibitor 99.86% 否
HY-19832 SC66 99.47% 否
HY-N6739 Beauvericin 99.95% 否
HY-153360 MC-GGFG-AM-(10Me-11F-Camptothecin) Inhibitor 98.06% 否
HY-15485 Zardaverine 98.73% 否
HY-115449 Chromeceptin 99.91% 否
HY-N0222 Avicularin 99.80% 否
HY-101519 BETd-260 99.59% 否
HY-147918 Anticancer agent 73 Inhibitor 99.92% 否
HY-19345A Vacquinol-1 dihydrochloride 99.44% 否
HY-139781 PD-L1-IN-1 Inhibitor 98.01% 否
HY-139434 JMJD6-IN-1 Inhibitor 99.69% 否
HY-150538 STAT3-IN-12 99.92% 否
HY-150750 ODN M362 / 否
HY-132177 α-L-Fucosidase, Microorganism / 否
HY-13267 Droxinostat 98.91% 否
HY-P5133 Synstatin (92-119) Inhibitor 97.16% 否
HY-137506 XST-14 99.26% 否
HY-115901 4-PQBH 99.08% 否
HY-121799A Taurohyocholic acid sodium salt 96.80% 否
HY-142956 ROS-ERS inducer 1 99.65% 否
HY-160765 WNTinib 99.95% 否
HY-W013514 2-Acetamidofluorene 98.83% 否
HY-10174 PD184161 98.08% 否
HY-121204 Iberverin Inducer ≥98.0% 否
HY-150750A ODN M362 sodium 93.61% 否
HY-N6896 Isoviolanthin Inhibitor 99.66% 否
HY-W011434 Triglycidyl isocyanurate ≥98.0% 否
HY-130173 Bafilomycin C1 ≥99.0% 否
HY-150072 DS89002333 Inhibitor 99.87% 否
HY-153901 PROTAC EGFR degrader 8 Inhibitor 98.90% 否
HY-157581 MS39 Degrader 99.2% 否
HY-16196 ENMD-1198 Inhibitor 98.87% 否
HY-131704 FGFR4-IN-5 Inhibitor 98.03% 否
HY-147187 MNK8 99.76% 否
HY-W001925 7-Methoxy-1-tetralone 99.93% 否
HY-19617A EGFR-IN-1 hydrochloride Inhibitor / 否
HY-19617 EGFR-IN-1 Inhibitor / 否
HY-119694 Rotenolone ≥97.0% 否
HY-119833 Rubone Modulator 99.1% 否
HY-146349 PROTAC EGFR degrader 4 Inhibitor / 否
HY-162616 SelSA 99.83% 否
HY-163490 PKMYT1-IN-1 Inhibitor / 否
HY-19617B EGFR-IN-1 TFA Inhibitor 99.38% 否
HY-N4168B Methyl chlorogenate 99.13% 否
HY-N5136 25(R,S)-Ruscogenin Inhibitor 99.83% 否
HY-W011616 Cardionogen 1 Inhibitor 99.21% 否
HY-157950 DSPE-PEG2000-triGalNAc ammonium 97.4% 否
HY-18750A Zorifertinib hydrochloride / 否
HY-101021 Ascochlorin / 否
HY-159147 SIA​​IS039 / 否
HY-100443 PX20606 Agonist / 否
HY-146407 Anticancer agent 53 Inducer / 否
HY-147515 FGFR4-IN-11 Inhibitor / 否
HY-151287 KRAS inhibitor-20 Inhibitor / 否
HY-19551 Apogossypolone / 否
HY-115902 FGFR4-IN-7 / 否
HY-120349 LL-Z1640-4 Inhibitor / 否
HY-120356 T-1101 / 否
HY-121160 Amiprilose Inhibitor / 否
HY-141813 Autophagy-IN-C1 Inhibitor / 否
HY-142945 KRAS G12C inhibitor 43 Inhibitor / 否
HY-143881 FGFR4-IN-6 Inhibitor / 否
HY-144605 PROTAC EGFR degrader 3 Inhibitor 97.39% 否
HY-144724 HSP90-IN-10 Inhibitor / 否
HY-144759 FGFR4-IN-9 Inhibitor / 否
HY-145389 SZ-015268 Inhibitor / 否
HY-146395 HBV-IN-23 / 否
HY-146422 PROTAC EGFR degrader 5 / 否
HY-146423 PROTAC EGFR degrader 6 / 否
HY-146504 Topoisomerase I/II inhibitor 3 / 否
HY-147793 FGFR4-IN-12 Inhibitor / 否
HY-149063 Antitumor agent-92 Inducer / 否
HY-149475 VEGFR-2-IN-33 Inhibitor / 否
HY-150596 CT1-3 / 否
HY-151461 CHNQD-01255 Inhibitor / 否
HY-155046 FGFR4-IN-14 Inhibitor / 否
HY-155139 Tubulin polymerization-IN-45 / 否
HY-155172 ZX-J-19j / 否
HY-155178 Antiproliferative agent-34 Inhibitor / 否
HY-155248 HL23 / 否
HY-158248 FGFR4-IN-19 Inhibitor / 否
HY-158439 anti-TNBC agent-7 Modulator / 否
HY-161373 PI3Kα-IN-22 Inhibitor / 否
HY-161617 LASSBio-2052 Agonist / 否
HY-161647 Antitumor agent-156 Inducer / 否
HY-161706 c-Fms-IN-15 Inhibitor / 否
HY-161824 Antiproliferative agent-52 / 否
HY-161825 Tubulin polymerization-IN-66 / 否
HY-161854 LASSBio-1911 Inhibitor / 否
HY-161934 PARP1-IN-27 / 否
HY-162099 VEGFR-IN-4 Inhibitor / 否
HY-162259 QC-182 Degrader / 否
HY-162650 SL44 Inhibitor / 否
HY-162679 c-Met degrader-1 / 否
HY-162890 EGFR-IN-122 Inhibitor / 否
HY-162968 MRTF-A-IN-1 Inhibitor / 否
HY-162969 MRTF-A-IN-2 Inhibitor / 否
HY-163461 4F-DDC Inhibitor / 否
HY-163491 PKMYT1-IN-2 Inhibitor / 否
HY-164349 WZ-2-033 Inhibitor / 否
HY-164372 17-Demethoxy-reblastatin / 否
HY-164410 MO-I-1100 Inhibitor / 否
HY-168029 eEF2K degrader-1 / 否
HY-168085 CV-4-26 / 否
HY-168187 Src Inhibitor 3 Inhibitor / 否
HY-168574 SZU-B6 / 否
HY-168609 CRI9 / 否
HY-169262 PLD-IN-1 / 否
HY-19345 Vacquinol-1 / 否
HY-D2312 Mito-Rh-S / 否
HY-E70272 2-Hydroxystearoyl-CoA / 否
HY-N11429 Glycochenodeoxycholic acid 3-glucuronide / 否
HY-N1244 Sarmentosin / 否
HY-N1260 Scutebarbatine A Inducer 98.76% 否
HY-N12601 Diselaginellin B Inducer / 否
HY-N6623 Malvidin-3-galactoside chloride / 否
HY-N7803 De-O-Methyllasiodiplodin Inducer / 否
HY-N8439 Questiomycin A / 否
HY-P10553 ARF(26–44), cell-permeable / 否
HY-W653905 Amantadine-d15 hydrochloride / 否
HY-121799 Taurohyocholic acid / 否
HY-123697 VE-465 Inhibitor / 否
HY-164384 DFX117 / 否
HY-164520 PMED-1 Inhibitor / 否
HY-168165 Adefovir diphosphate / 否
HY-17386S1 Rosiglitazone-d4 / 否
HY-N2858 Alpinumisoflavone acetate Inducer / 否
HY-N7507A Sempervirine nitrate Inhibitor / 否
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