Il6 - interleukin 6 Gene

中文名称：白细胞介素 6

种属: Rattus norvegicus

同用名: ILg6; Ifnb2

关于 Il6

功能概要

该基因编码的蛋白可启动细胞因子活性和白细胞介素 6 受体结合活性。参与多个过程，包括细胞对脂质的反应；细胞通讯的正向调节；和对肽激素的反应。位于细胞质和细胞外空间。用于研究多种疾病，包括急性坏死性胰腺炎；弥散性血管内凝血;脂肪肝病；高血压（多发性）；和阳痿。多种疾病的生物标志物，包括急性坏死性胰腺炎；动脉疾病（多发性）；听觉系统疾病（多种）；缺铁性贫血;和肺部疾病（多种）。该基因的人类直系同源物与多种疾病有关，包括自身免疫性疾病（多种）；眼病（多发）；胃肠系统癌症（多发性）；糖代谢疾病（多种）；和牙周病（多种）。与人 IL6（白细胞介素 6）同源。 [由基因组资源联盟提供，2022 年 4 月]

Enables cytokine activity and interleukin-6 receptor binding activity. Involved in several processes, including cellular response to lipid; positive regulation of cell communication; and response to peptide hormone. Located in cytoplasm and extracellular space. Used to study several diseases, including acute necrotizing pancreatitis; disseminated intravascular coagulation; fatty liver disease; hypertension (multiple); and impotence. Biomarker of several diseases, including acute necrotizing pancreatitis; artery disease (multiple); auditory system disease (multiple); iron deficiency anemia; and lung disease (multiple). Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); eye disease (multiple); gastrointestinal system Cancer (multiple); glucose metabolism disease (multiple); and periodontal disease (multiple). Orthologous to human IL6 (interleukin 6). [provided by Alliance of Genome Resources, Apr 2022]