1. Gene
  2. Mical1 - microtubule associated monooxygenase, calponin and LIM domain containing 1 Gene

Mical1 - microtubule associated monooxygenase, calponin and LIM domain containing 1 Gene

种属: Mus musculus

同用名: MICAL; Nical; MICAL-1

基因 ID: 171580 | 基因类型: protein coding

关于 Mical1

功能概要

Enables several functions, including FAD binding activity; actin binding activity; and Enzyme binding activity. Involved in several processes, including actin filament depolymerization; negative regulation of cellular protein metabolic process; and sulfur oxidation. Located in hippocampal mossy fiber expansion. Orthologous to human MICAL1 (microtubule associated monooxygenase, calponin and LIM domain containing 1). [provided by Alliance of Genome Resources, Apr 2022]

Mical1 基因产物(4)

mRNA Protein Name
NM_001164433.1 NP_001157905.1 [F-actin]-monooxygenase MICAL1 isoform 2
NM_001358838.1 NP_001345767.1 [F-actin]-monooxygenase MICAL1 isoform 3
NM_001358839.1 NP_001345768.1 [F-actin]-monooxygenase MICAL1 isoform 4
NM_138315.2 NP_612188.1 [F-actin]-monooxygenase MICAL1 isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables FAD binding IDA
IDA: 通过直接分析推断
26935886 MGI
enables actin binding IDA
IDA: 通过直接分析推断
23911929 MGI
enables monooxygenase activity IMP
IMP: 通过突变表型推断
16275926 MGI
enables oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen IDA
IDA: 通过直接分析推断
23911929 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
21730291 MGI
enables protein kinase binding IDA
IDA: 通过直接分析推断
25007825 MGI
enables small GTPase binding IPI
IPI: 通过物理相互作用推断
18094055 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in actin filament depolymerization IDA
IDA: 通过直接分析推断
23911929 MGI
involved in negative regulation of apoptotic process IMP
IMP: 通过突变表型推断
21730291 MGI
involved in negative regulation of cysteine-type endopeptidase activity involved in apoptotic process IMP
IMP: 通过突变表型推断
21730291 MGI
involved in negative regulation of protein phosphorylation IMP
IMP: 通过突变表型推断
21730291 MGI
involved in regulation of regulated secretory pathway IMP
IMP: 通过突变表型推断
25007825 MGI
involved in sulfur oxidation IDA
IDA: 通过直接分析推断
23911929 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in hippocampal mossy fiber expansion IMP
IMP: 通过突变表型推断
25007825 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

[F-actin]-monooxygenase MICAL1

F-actin-monooxygenase MICAL1

CasL interacting molecule MICAL

NEDD9-interacting protein with calponin homology and LIM domains

[F-actin]-methionine sulfoxide oxidase MICAL1

microtubule associated monoxygenase, calponin and LIM domain containing 1

molecule interacting with CasL pro

Mical1 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
Mical1 Q8VDP3 Stk38 Mus musculus Q91VJ4
Anti Tag CoIP
21730291
种属间
Mical1 Q8VDP3 Stk38l Rattus norvegicus A4GW50
Anti Tag CoIP
21730291
种属间: 跨种属相互作用 种属内: 同种属相互作用

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Mical1 NCBI NCBI:64780